The invention relates to a
system (1) for real-
time synchronization of
biological data with
millisecond-level time precision. The
system comprises a screen (10) for displaying visual stimuli; a
control unit (20) connected to the screen (10) for transmitting visual stimuli; an optical sensor (30) connected to the screen (10) for detecting a visual stimulus; a
neuron activity measurement device (40) having an internal
clock (41) connected to the
control unit (20) for transmitting
neuron activity recorded by the internal
clock (41); a feedback device (50) comprising a plurality of depression buttons (51) adapted to detect a response of the subject to the visual stimuli, and a stop button (52) adapted to stop the display of the visual stimuli. The
system (1) is characterized by the fact that it comprises a
microcontroller (60) with a real-time
clock (61) connected to the optical sensor (30) and to a feedback device (50) for real-time recording of their events with
millisecond-level accuracy using the real-time clock (61), where the
microcontroller (60) is capable of generating a synchronized
time signal for each recorded event, and the feedback device (50) is capable of generating a synchronized
time signal for each recorded event. And a
microcontroller (60) connected to the
control unit (20) for transmitting the recorded events and their associated synchronization time signals; wherein the control unit (20) is configured such that it is adapted to receive each event recorded by the real-time clock (61) and neuronal activity events recorded by the internal clock (41), and to associate them based on the synchronization
time signal. The system further comprises an opto-
isolator (70) adapted to provide electrical insulation of the connection between the microcontroller (60) and the neuronal
activity measurement device (40). The invention also relates to a method for a system (1) for real-
time synchronization of
biological data of a subject with
millisecond-level time accuracy.