This invention relates to the field of radioactive
separation technology, and discloses an automated solution preparation and delivery control method and
system for At-211 separation, comprising: Step 1, determining the column
bed volume, setting the minimum operating volume particle size, and determining the pump
running time; Step 2, solidifying the
reagent and matching it with the valve inlet, obtaining the
background current and determining the low
threshold current, high
threshold current,
tail threshold current, and volume confirmation rules for the
buffer solution; Step 3, generating the loading solution; Step 4, delivering the low-
acid washing column solution,
buffer solution, and preset equilibration solution to obtain the
separation column; Step 5, loading the sample and comparing the output current of the
ionization chamber with the low threshold current and high threshold current to determine the three states; Step 6, switching the collection valve to the product
bottle and
cutting off the organic
elution solvent; Step 7, controlling the collection valve and determining the actual product volume. This invention achieves automated and quantitative control of solution preparation, delivery,
elution, and collection during the At-211
separation process.