The application relates to a serum-loaded ionic catgut and a preparation method thereof, and belongs to the technical field of
traditional Chinese medicine external treatment. The preparation method of the serum-loaded ionic catgut comprises the following steps: performing ionic surface treatment on medical absorbable catgut to obtain ionic catgut, and immersing the ionic catgut in
autologous serum of a patient to obtain the serum-loaded ionic catgut after soaking. The serum-loaded ionic catgut takes the
autologous serum of the patient as a core treatment material, has excellent
biocompatibility and no rejection risk, and has completely individualized active ingredients, so that the serum-loaded ionic catgut can adjust to the
pathological state of the patient itself, breaks through the limitation of traditional buried thread "one
drug thread is universal", and realizes truly individualized precision treatment.