9 results about "Mycosis" patented technology

The invention discloses a construction method of a novel composite biocontrol flora for preventing and treating cotton verticillium wilt, and relates to the technical field of biological prevention and treatment of agricultural plant diseases. The bacillus polymyxa and the bacillus cereus with the optimal antagonistic activity are respectively screened out through plate confrontation and buckling tests, and the bacillus pseudomycoides is obtained through screening by taking the growth promoting capability of dissolving phosphorus and producing indoleacetic acid as indexes. Through pairwise cross culture verification, the three strains are completely compatible and have no mutual inhibition effect. The method comprises the following steps: respectively and independently activating the three strains, carrying out enlarged culture, preparing single bacterial liquid with the OD600 value of 1.0, and uniformly mixing according to a volume ratio, so as to obtain the novel composite biocontrol flora for preventing and treating the cotton verticillium wilt. According to the invention, antagonistic bacillus and growth-promoting bacillus with complementary functions are screened, single bacteria are independently cultured and then are compounded according to a ratio of 1: 1: 1 to construct a composite flora, so that the synergistic interaction of efficient prevention and control of cotton verticillium wilt, cotton growth promotion and soil phosphorus solubilization is realized.

The application discloses a kind of multiple qPCR detection primer combinations of superficial mycosis pathogen, it includes the specific primer and probe of detecting Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Microsporum audouinii, Microsporum gypseum, Candida albicans, Malassezia furfur;The application detects pathogen target gene using real-time fluorescent quantitative PCR technology;The method has the advantages of short time consumption, high specificity, low cost, and can detect multiple pathogens at a time, provides a convenient method for the detection of superficial mycosis pathogen, and has important significance for the early molecular diagnosis of superficial fungal infection patients.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a compound ointment preparation for treating fungal infection and a preparation method and application thereof. According to the compound ointment preparation, chlortetracycline hydrochloride, econazole nitrate and triamcinolone acetonide compound serve as core components, no chemical incompatibility exists among chlortetracycline hydrochloride, econazole nitrate and triamcinolone acetonide, and comprehensive treatment on external auditory canal mycosis is achieved through the pharmacological synergistic effect. Meanwhile, adaptive plant essential oil is specially selected, and the proportion of active ingredients is optimized, so that the compound ointment preparation can effectively control bacteria, fungi and inflammation, the hormone amount is obviously reduced, and side effects are reduced.

The invention provides lactobacillus plantarum NX87 and application thereof, the lactobacillus plantarum NX87 is lactobacillus plantarum NX87, the lactobacillus plantarum NX87 is preserved in the Guangdong Microbial Culture Collection Center on April 23, 2025, the address is No.59 building, No.100 courtyard, Xianlie Middle Road, Guangzhou, and the preservation number is GDMCC No. 66203; the lactobacillus plantarum NX87 is used for preventing and treating the streptococcus suis, the escherichia coli and the balloon mycosis, and the lactobacillus plantarum NX87 is used for preventing and treating the streptococcus suis, the escherichia coli and the balloon mycosis. The strain disclosed by the invention has relatively strong inhibition capability on streptococcus suis, escherichia coli and balloon mycosis, has relatively strong tolerance to acid, has good cholate tolerance, and is beneficial to colonization at parts such as intestinal mucosa and the like.

The invention relates to the use of kahalalide-type depsipeptide compounds of formulae I and / or II, obtained from the green alga Pedobesia sp., for controlling a broad spectrum of fungal plant pathogens. The invention also encompasses fungicidal compositions comprising said compounds with a phytologically acceptable carrier, a process for their preparation from Pedobesia biomass, and their use for the preparation of a medicament for treating mycosis such as that caused by Candida albicans or Trichophyton rubrum.

Methods and compositions for treating, preventing and controlling fungal infections, including superficial infections, using compounds of the β-carboline class are disclosed. Pharmaceutical compositions comprising β-carbolines alone, or in combination with therapeutically effective amounts of an antimycotic, are administered to a subject to treat or prevent a superficial fungus infection such as those caused by fungi selected from the Candida or Trichophyton genus, infections such as dermatomycosis, diaper rash (yeast dermatitis), athletes' foot (tinea pedis), jock itch (tinea cruris), ringworm (tinea capitis) and cutaneous candidiasis. Methods of treating, preventing or controlling fungal infections in a plant are also disclosed, wherein a composition comprising an agriculturally acceptable amount of a β-carboline and a fungicide is administered to the plant and / or the locus of the plant, β-carbolines having the following formula are preferred. (Formula I).

The invention discloses a primer group for simultaneously detecting eight pet dermatophytes and application of the primer group. The primer group comprises a forward PCR (Polymerase Chain Reaction) amplification primer, a reverse PCR amplification primer and a control primer sequence and a template of eight pet skin fungi, wherein the eight pet skin fungi comprise microsporum canine, microsporum gypsiformis, malassezia, megasporum, trichophyton mentagrophytes, trichophyton fibraureae, histoplasma capsulatum and globularia; the sequences of the primers are respectively shown as SEQ ID NO.1-SEQ ID NO.19. The primers can detect eight pet dermatomycosis, have very high sensitivity and specificity, have certain development, utilization and popularization values, and can provide technical support for clinical diagnosis of pet dermatomycosis.

This invention provides a compound called *Paris polyphylla* saponin A, its pharmaceutical composition, preparation method, and application, belonging to the fields of pharmaceutical technology and cosmetic technology. It provides *Paris polyphylla* saponin A, as well as *Paris polyphylla* saponins A-D and *Paris polyphylla* saponin A in the preparation of drugs for the prevention and treatment of superficial fungal infections of the skin. The above compounds are effective against *Trichophyton rubrum* (…). Trichophyton rubrum Epidermophyton floccosum ( Epidermophyton floccosum ) and Microsporum gypseum ( Microsporum gypseum It has a significant inhibitory effect on dermatophytes such as dermatophytes and can be used to prepare drugs for the prevention and treatment of superficial fungal infections of the skin.

The invention relates generally to the treatment of onychomycosis and, more particularly, to the treatment of onychomycosis using compositions comprising trichostatin A (TSA) and compositions for use in such methods.