31 results about "Microscopic exam" patented technology

The invention discloses a microbial spatial distribution monitoring method and system based on a multi-level microscopic scanning image, relates to the technical field of image processing, and is used for carrying out multi-level grid traversal type scanning image acquisition on an observation area of microscopic examination data. Identifying and counting the number of each target microorganism in each image and the position information of each target microorganism in the corresponding hierarchical grid, and storing the information into a to-be-identified hierarchical data set corresponding to each target microorganism; and according to the ecological type of each target microorganism, respectively inputting the corresponding to-be-identified hierarchical data set into the corresponding trained multi-organism distribution probability density model to obtain a spatial distribution rule of each microorganism in the microscopic examination data. By adopting multi-stage magnification grading scanning, the interaction and distribution rules among microbial species are respectively described according to microbial ecological types, and the accuracy of microbial distribution observation is improved.

The preparation method of the visible component microscopic examination sample comprises the following steps: preparing at least two samples with different light transmittances, and selecting at least two different sample treatment methods; comprising any two treatment methods as follows: a method A: for a light-proof to-be-detected sample, taking a set volume of light-proof sample, adding a set volume of water into the light-proof sample, and diluting to obtain an intermediate sample; taking the intermediate sample, and adding a reagent with a set volume or a set weight to obtain a microscopic examination sample; the method B comprises the following steps: for a to-be-detected semi-transparent sample, taking a semi-transparent sample with a set volume, and adding a reagent with a set volume or a set weight to obtain a microscopic examination sample; the method C comprises the following steps: enriching a light-transmitting sample with a set volume for a light-transmitting to-be-detected sample, and adding a reagent with a set volume or a set weight into an enriched intermediate sample with a set volume to obtain a microscopic sample. Corresponding methods are selected according to different light transmittances of the to-be-detected samples, so that the to-be-detected samples in different states can be prepared into microscopic examination samples suitable for efficient imaging of a microscope.

In the preparation method of the visible component detection dry reagent, the redissolving reagent and the microscopic examination sample, the visible component detection dry reagent is formed by drying a liquid dyeing reagent; the liquid staining reagent comprises a staining agent and an acid-base regulator; the pH regulator is used for regulating the pH value of the liquid dyeing reagent; the liquid dyeing reagent is filtered before being dried. Before drying, dividing the liquid dyeing reagent into small parts, and drying separately; the liquid dyeing reagent is divided into single parts with set volume, and then is dried to remove moisture. The single part of the set capacity is 300 ul to 3000 ul per piece. The visible component is used for detecting the dry reagent, so that the reagent is more convenient to store and transport, and the quality guarantee period is longer.

This invention relates to the field of sputum smear cytology examination technology, and discloses an automated sputum cell analysis method and system based on deep learning. The method includes specimen collection and preprocessing, image preparation and acquisition, data preprocessing and dataset construction, improved YOLOv8 algorithm training, cell identification and statistics, large-scale model analysis, and report generation. This invention automates sputum cell analysis, significantly reducing specimen processing and interpretation time. The efficiency of each specimen analysis is several times higher than manual microscopic examination, reducing labor costs and efficiently handling the demand for large-scale specimen testing. The improved YOLOv8 algorithm, through the C2f-DCNv3 module, SPD-Conv, and color and texture attention mechanisms, accurately captures the differential characteristics of similar cells, significantly improving cell classification accuracy, reducing subjective and fatigue errors in manual interpretation, and resulting in more objective and reliable results.

The invention relates to the technical field of medical engineering, in particular to a microscope lifting support for medical engineering, which comprises a detection platform, a lifting rod, a microscope connecting frame, a bubble level, a connector, a positioning rod, a correction assembly and a balance base, the right side of the movable part is connected with a first control bolt, the left end of the movable part is fixedly provided with a microscope connecting frame, and the front end of the microscope connecting frame is connected with a second control bolt; according to the invention, through ingenious cooperation of the bubble level, the positioning rod and the correction assembly, the angle of the detection platform can be flexibly adjusted to realize rapid calibration, so that horizontal installation of the detection platform is ensured, and the problem that fluid detection objects overflow due to slight inclination of the object carrying platform is prevented; the support has the advantages of being flexible in control and correction, convenient to adjust and the like, and provides powerful support for microscopy in the field of medical engineering.

The invention discloses an inspection method for rapidly processing a wire rod metallographic specimen, and belongs to the technical field of metallographic detection. The invention provides an inspection method for rapidly processing a wire rod metallographic specimen in order to solve the problems of inconvenience in specimen processing operation marking, long inspection time, material mixing and material loss during hook-by-hook sampling inspection of a wire rod bearing steel rolling body product. The method comprises the steps of incoming material acceptance check, sample sorting, sample processing, metallographic sample preparation and microscopic examination, an auxiliary device is made of 45 # steel and is of a cuboid structure of 390mm * 75mm * 50mm, circular grooves are formed in the upper surface of the auxiliary device and are arranged in the width direction of the auxiliary device, every two circular grooves form one group, and ten groups of circular grooves are arranged; the diameter of each circular groove is 30 mm, the depth of each circular groove is 30 mm, and the gap between every two adjacent circular grooves is 5 mm. By adding an auxiliary device and a new technological process method, one-person operation can be reduced, the processing time is shortened by half, the probability of sample mixing and losing is 0%, and the accuracy and the efficiency of hook-by-hook inspection of the wire rod are greatly improved.

This invention discloses a self-cleaning, anti-interference snail crushing device and its usage method for microscopic examination. The device includes a main body, a flat crushing unit, a snail placement unit, a pressure plate cleaning unit, and a snail placement plate detachably installed on the upper surface of the snail placement unit for placing and positioning snails. It employs automated pressure application technology, solving the technical problem that manual crushing methods inevitably cause uneven stress on the snails and varying degrees of crushing when handling a large number of snails for microscopic examination, thus affecting the quality of subsequent microscopic examinations. Furthermore, by integrating the pressure plate cleaning unit into the device, the pressure plate cleaning scheme is optimized, improving the efficiency of snail crushing. Simultaneously, multiple snail placement grooves are provided within the snail placement plate, effectively solving the problem of difficulty in neatly arranging snails during simultaneous crushing and microscopic examination of a large number of snails, and the technical problem of cross-contamination of fluids from adjacent crushed snails.

Each of the multifunctional detection sample accommodating device and the multifunctional detection device comprises a detection part A and a detection part B; the detection part A comprises a cavity A; the cavity A is used for accommodating a sample A, the cavity A is used for shooting a microscopic magnification image of a microscopic examination sample, and the microscopic magnification image is used for visible component analysis; the detection part B comprises a cavity B; the cavity B is used for accommodating a sample B, the cavity B is used for optical detection analysis of the sample, and the optical detection analysis is used for detection-free analysis of the sample B. The multifunctional detection device comprises a microscopic amplification digital imaging assembly and an optical detection assembly, the microscopic magnification digital imaging assembly is used for shooting a microscopic magnification image of the microscopic examination sample; and obtaining an image of the sample in the cavity A for visible component analysis. Light in the optical detection assembly irradiates a sample in a cavity B of the external multifunctional detection device, and detection-free analysis of the sample is carried out according to optical reaction characteristics of the sample.

This application relates to a method, apparatus, computer device, and storage medium for executing sample detection tasks. The method includes: receiving a sample detection instruction; responding to the sample detection instruction, sequentially determining whether there are any tasks to be executed in the task queue corresponding to each detection task type according to the priority order of each detection task type in a set of detection task types; if there are tasks to be executed in the current detection task type, then designating the tasks to be executed as target detection tasks; controlling a sample position transformer to perform position transformation according to the task execution position corresponding to the target detection task, so that the target detection sample corresponding to the target detection task is located at the task execution position, and executing the task operation corresponding to the target detection task at the task execution position. This method can improve the execution effect of microscopic examination tasks.

The invention discloses a multi-mode ultrasonic scanning and high-power microscopic examination fused plastic package device chip bonding layer layering judgment method, relates to the technical field of plastic package device defect detection, and aims at a plastic package device composed of a plastic package material, a chip, a bonding layer, a back exposed substrate and a lead frame. Firstly, the layering possibility below a chip is preliminarily judged through front C scanning, and T scanning is synchronously used for proving abnormity; the layering condition is verified from the depth dimension through back C scanning and B scanning, and each ultrasonic scanning mode is clear in parameter setting so as to guarantee the detection consistency; and finally, preparing a sample for the layered device, and visually confirming defects through microscopic examination of a 10000-times high-power microscope. According to the method, multi-mode ultrasonic scanning and high-power microscopic examination are fused, theoretical analysis and actual verification are combined, detection is comprehensive, judgment is accurate, and the method is not only suitable for chip bonding layer layering, but also can be used for defect judgment of plastic package material cavities, layering of substrates and plastic package materials and the like, and is wide in applicability.

The invention discloses a preparation method of a monoclonal antibody for detecting trichophyton rubrum and application of the monoclonal antibody in fungal skin disease detection, and belongs to the field of biological medicine. The monoclonal antibody provided by the invention only has specific reaction with trichophyton rubrum, and has no cross reaction with common fungi such as trichophyton mentagrophytes, epidermophyton flocculent, candida albicans, malassezia and the like and normal flora of a human body, so that a false positive result is effectively avoided. Based on the double-antibody sandwich principle, the detection sensitivity can reach 200 pg / mL level, trace trichophyton rubrum in a clinical sample can be detected, and the positive rate is obviously higher than that of direct microscopic examination. The whole detection process can be completed within 15-20 min and is far faster than fungus culture for several weeks, a rapid diagnosis basis can be provided for doctors, and early treatment is facilitated. The kit provided by the invention has standardized operation steps, does not need complex instruments and special training, and is suitable for popularization and use in clinical laboratories of hospitals at all levels, outpatient clinics of dermatology and even basic medical institutions.

The utility model relates to the technical field of sample smearing equipment, and discloses sample smearing equipment capable of quickly drying, which comprises a drying box, a storage box and a telescopic dyeing frame arranged at the bottom of the equipment, a drying frame, a temperature sensor, a time controller, a small fan and a small ozone generator are arranged in the drying bin; the telescopic dyeing frame is provided with a silica gel suction cup pad and a dyeing liquid anti-overflow partition plate, the drying frame is of a push-pull structure, the surface of the drying frame is provided with an anti-skid pad, and the small ozone generator is used for disinfecting the drying bin and the peripheral environment. According to the utility model, the telescopic dyeing frame is matched with the silica gel suction cup pad and the anti-overflow partition plate, so that stable fixation and liquid spilling prevention during smear dyeing are realized in a shaking environment such as a ship, and temperature sensing, time control and a hot air circulating system in the drying bin can accelerate smear drying and guarantee film integrity; and the preparation speed and quality of the microscopic examination specimen are obviously improved.

The invention discloses a construction method of a Dcaf17 gene modified golden hamster model and application of the Dcaf17 gene modified golden hamster model. The method comprises the following steps: under a red light source, injecting a Cas9 functional element and sgRNA of a targeted Dcaf17 gene exon 1 through a two-cell embryo, and transplanting the embryo into a receptor body, so as to obtain the Dcaf17 gene modified golden hamster. The Dcaf17 gene modified golden hamster model is constructed by utilizing two-cell stage embryo gene editing, and the Dcaf17 gene modified golden hamster homozygous male rat has the phenotype characteristics of no fertilization ability, normal testis and the like, and is used for replacing ligation male rats to prepare false pregnancy receptor rats. The receptor can efficiently identify and utilize a false pregnancy receptor through microscopic examination of sperms by a microscope. Therefore, the invention solves the technical difficulty of receptor preparation in related experiments of assisted reproduction of the golden hamster, and can be used for phenotype research of the Dcaf17 gene and related applications of assisted reproduction of the golden hamster.

The application provides a pollen grain target detection system and method fusing multiple morphological priors, and relates to the technical field of pollen detection. The application comprises the following steps: performing feature extraction on a pollen grain image to be detected to obtain an initial feature map, convolving the initial feature map using a pre-constructed morphological kernel library to obtain a morphological response feature map; performing adaptive weighted feature fusion based on the morphological response feature map to obtain a morphological confidence map; processing a fusion feature obtained based on the morphological confidence map and a global context feature extracted from the initial feature map to obtain a spatial attention map; performing feature re-labeling on the initial feature map using the spatial attention map to obtain an enhanced feature map, and then performing target detection on the enhanced feature map to obtain pollen grain information output. The beneficial effects are as follows: effectively solving the problems of multiple background interferences and difficult morphological differentiation in pollen automatic detection, supporting high-time-efficiency pollen concentration monitoring, and overcoming the disadvantages of traditional manual microscopic examination processes, such as complexity, long cycle and dependence on professional personnel.

The application discloses a blood pushing machine and method. The blood pushing machine comprises a pushing device, an image processing device and a dyeing device. The pushing device is used for pushing and processing a sample to be detected on a blood smear to form a blood film sample on the blood smear. The image processing device is used for acquiring a detection image of the blood film sample and determining whether the blood smear meets a qualified condition based on the detection image. The dyeing device is used for dyeing and processing the blood film sample on the blood smear meeting the qualified condition. Through the above implementation, whether the blood smear meets the qualified condition is determined based on the detection image, and then the dyeing device only dyes and processes the blood film sample meeting the qualified condition, so that the quality of the blood film is greatly improved, and the problem of low microscopic examination efficiency caused by unqualified smears is solved.

The present invention pertains to a heterogeneous mixture separation process and to use thereof for the detection of gastrointestinal parasites in humans and animals. The process proposed herein, in an unprecedented manner, comprises steps for preparing faecal material, saturating water with dissolved air, employing surfactants and chemical polymers with positive and negative ionic forces, separating the processed faecal material by means of dissolved air flotation, and using the material of interest for microscopic examination.

The invention provides a skin fungus microscopic examination image identification method and system, and the method comprises the steps: determining a high-frequency component and a low-frequency component of a fungus microscopic examination image, and reconstructing the fungus microscopic examination image into a denoised clear image; synchronously extracting optical features of spore edges during optical diffraction and texture features of spore surface textures for multi-channel feature fusion to obtain an enhanced texture feature map during fungal microscopic examination; according to a spatial topological relation of different feature units in the enhanced textural feature map in a preset neighborhood, generating discrimination features of a spore configuration, and further determining a confidence level of a spore target in the different feature units in the enhanced textural feature map through the discrimination features; and performing adaptive threshold segmentation on the enhanced texture feature map based on all confidence levels, and generating a confidence detection report of the fungal spores on the skin of the patient through a segmentation result. By adopting the scheme of the invention, the key identification features of the spores can be completely reserved while the image noise is inhibited.

This application discloses a slide reading device and a slide reading method. The slide reading device includes: a sample feeding device for feeding a sample slide to be tested; a slide transfer device for picking up a target slide from the sample slide and transferring the target slide to an operating position, the operating position including an oil-dropping position and a microscopic examination position; an oil-dropping device corresponding to the oil-dropping position and used to perform an oil-dropping operation on the target slide located at the oil-dropping position; and a microscopic examination device for performing a microscopic examination operation on the target slide located at the microscopic examination position. The slide reading device provided in this application performs a preset oil-dropping operation on the target slide transferred to the oil-dropping position through the oil-dropping device corresponding to the oil-dropping position, which solves the problems of the complex structure and large volume of existing slide reading devices, as well as the problems of the lengthy slide reading process and the long processing time.

The invention discloses a visible component detection module preheating device and a visible component microscopic examination sample preparation method. The visible component detection module preheating device comprises a control module, a heating plate and a supporting assembly, the supporting assembly is used for supporting; the control module is installed in the supporting assembly. The heating plate is mounted on the supporting assembly; the heating plate is used for placing a component detection module; the heating plate is used for raising the temperature of the visible component detection module; the control module is electrically connected with the heating plate; the control module is used for providing electric energy for the heating plate. And a suitable temperature condition is provided for the visible component detection module, so that the state of the visible component in the visible component detection module is ensured to be a state suitable for microscopic imaging and recognition.

A microscope, which is a confocal microscope converted into a light sheet microscope, includes a microscope body and a mechanical receiving apparatus for microscope objectives, through which a microscope beam path extends. An optical module attachable to the receiving apparatus is configured to illuminate a sample volume and collect and transmit light from the sample volume. The optical module comprises: first and second optical arrangements with first and second beam paths that intersect in the sample volume, an optical beam path selector configured to combine the first and / or second beam path with the microscope beam path, and an attachment element arranged between the first or second optical arrangement and the sample volume, wherein the first or second beam path extend at least in sections through the attachment element in order to generate a light sheet. An area sensor is configured to detect light collected from the sample volume.

The present application belongs to the technical field of food source research of relic gull, and particularly relates to a kind of relic gull feces microscopic examination device, including sample sampling tube and isolator cover, and microscope and object table are arranged in isolator cover, and slide placing table is arranged on isolator cover, and placing opening is arranged on placing table, and first conveying belt, first telescopic positioner and second telescopic positioner are arranged on object table, and collecting groove is installed in isolator cover, and step motor and placing tube are installed on isolator cover, and connecting shaft is connected on the rotating shaft of step motor, and mounting shaft is installed on connecting shaft, and mounting frame and mounting frame are installed on mounting shaft, and through hole is formed on mounting frame, and C type buckle and top ring are arranged on mounting frame, and U type frame is installed on isolator cover, and boss is arranged on U type frame, and recovery groove is installed in isolator cover, and pry plate is arranged above recovery groove, for solving the problem that relic gull feces microscopic examination is manually operated at present, and directly contacted with sample, which affects the health of test personnel.

The disposable sampling file for dermatological fungus microscopic examination comprises a knife handle and a knife body fixed on the knife handle, and the knife body is provided with a scraper part and a file part; the temporary storage strip is mounted on the knife body; the protective shell is rotationally mounted on the knife handle; the locking assembly is used for limiting rotation of the protective shell, the rasping function and the scraping function are integrated, two tools do not need to be used, materials are saved, the protective shell can protect the tool body, a user is prevented from touching the tool body by mistake, safety is improved, the temporary storage groove is formed in the tool body, and the safety of the user is improved. And the temporary storage strip which can be taken down is mounted in the temporary storage groove and is used for temporarily storing the samples, so that the convenience of taking the samples is improved.

The invention relates to a temperature control unit for microscopic examination of living cells and tissues, for precisely heating both the tissue and the fluid supplying the tissue to the desired temperature, and for maintaining a constant body temperature of animals under anesthesia for prolonged periods of time, which produces electrical noise that is either completely absent from electrophysiological recordings or so minimal that it does not affect the recordings.

The utility model discloses a tablet pressing device for improving a Krattan thick smear method. The utility model comprises a glass slide base, wherein the upper surface of the glass slide base is provided with a clamping groove for fixing a glass slide; the spring supporting rod is mounted on the glass slide base and is used for supporting the slide pressing plate and providing elastic support; the knob type sheet pressing plate is connected with the spring supporting rod and is used for performing sheet pressing operation on a feces sample on a glass slide, the knob type sheet pressing plate comprises a knob disc and a sheet pressing fixing plate, and the sheet pressing fixing plate is attached to and separated from the glass slide through the spring supporting rod. The device is used for tabletting by adopting an improved thick smear method, so that the thickness and the size of a tablet can be well controlled, excrement is prevented from overflowing when the smear is pressed, each smear manufactured by the device is standardized, and a quality guarantee is provided for subsequent microscopic examination of a microscope.

A system and procedure are provided for collecting and analyzing airborne particles at a user's site. The system includes a blower module for mobilizing dust from surfaces, a sampling system with an integrated vacuum pump for collecting particles on a slide for microscopic examination, and a mobile microscope for analyzing the collected particles. The system also includes an artificial intelligence (AI) module for classifying and counting particle types, and an app connectivity module for wireless communication with a mobile device. The procedure involves using the powerful blower to remove dust from surfaces, collecting particles on a slide, and analyzing the collected particles using the mobile microscope and the AI ​​modules.The system enables the analysis of airborne particles and allows users to detect and monitor particle concentrations in their environment. The system is delivered in a shipping / packaging box.

The invention relates to the technical field of cell detection, in particular to a centrifugal blood cell sheet pushing device which comprises a centrifugal disc and a sheet pusher. The slide pushing device is detachably arranged on the centrifugal disc, an adhesive glass slide is obliquely fixed in the slide pushing device, a blood guide plate is arranged above the adhesive glass slide, a gap with a high front part and a low rear part is formed between the blood guide plate and the adhesive glass slide, and a blood sample is dispersed in the gap due to a capillary effect; and under the action of centrifugal force, the glass slide is continuously turned upwards and forwards, and finally a uniform ultrathin or single-layer cell coating is formed on the adhered glass slide. The problems that a traditional manual blood pushing piece is not uniform in thickness and is greatly influenced by manual operation factors are solved, an ultrathin or single-layer cell coating can be stably obtained, the microscopic examination efficiency and accuracy of a pushing piece sample are improved, the blood cell pushing piece operation is standardized, and the working efficiency is improved. The method has important significance in improving the morphological diagnosis rate, the detection efficiency and the accuracy of the blood cells.

The invention discloses endoscopic detection equipment and Brillouin microscopic detection equipment used for the endoscopic detection equipment. A Brillouin microscopic detection device for an endoscopic detection device comprises a first laser module, a second laser module, an optical fiber and a detection assembly. The first laser module generates pump light and the second laser module generates cost-oscillating light. The optical fiber transmits the pump light to irradiate the portion to be detected to generate spontaneous Brillouin scattering light. The optical fiber transmits the spontaneous Brillouin scattering light to the detection module. The detection module receives the spontaneous Brillouin scattered light and the local oscillator light to perform heterodyne detection thereon to generate a detection result, which is processed to perform Brillouin microscopic detection.

This invention discloses a smart wastewater treatment method and system based on data fusion, relating to the field of wastewater treatment technology. Compared with traditional monitoring methods that rely on a single indicator, this invention integrates key parameters such as pollutant type, sludge volume index, and filamentous bacteria biomass, and combines them with a dynamic normalization algorithm to generate a comprehensive pollution load index. This allows for more accurate identification of the coupling effect between organic matter impact and filamentous bacteria activity, avoiding misjudgment based on a single parameter. Furthermore, by triggering a response strategy with a preset threshold, regulation can be initiated at the initial stage of filamentous bacteria activity exceeding the standard. Compared with the traditional microscopic examination method with a lag of 4-8 hours, the response speed is effectively improved. At the same time, using the recovery of floc structure as the termination condition can avoid carbon source waste caused by over-regulation and shorten the system recovery cycle by 30%.

In the preparation method of the visible component detection freeze-drying reagent, the redissolving reagent and the microscopic examination sample, a coloring agent is included; preparing a dyeing base solution from the dyeing agent and water; filtering the dyeing base solution to form a dyeing solution; and removing moisture in the staining solution by freezing to obtain the visible component detection freeze-drying reagent. Comprising an acid-base regulator; preparing a dyeing base solution from the dyeing agent, an acid-base regulator and water; filtering the dyeing base solution to form a dyeing solution; and removing moisture in the staining solution through freeze drying to obtain the visible component detection freeze-drying reagent. Comprising an excipient; preparing a dyeing base solution from a dyeing agent, an excipient and water; and removing moisture in the dyeing base solution through freeze-drying to obtain the visible component detection freeze-drying reagent. And the visible component is used for detecting the freeze-dried reagent, so that the reagent is more convenient to store and transport, and the shelf life is longer.