Liquid dressing and preparation method thereof

A technology of liquid dressing and film-forming agent, which is applied in medical science, bandages and other directions, can solve the problems of high skin irritation, affect the use experience, and high cost, and achieve the effects of simple preparation method, blocking bacterial infection, and safe ingredients.

Pending Publication Date: 2019-09-20
SHAANXI BIO REGENERATIVE MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this technical solution, a relatively high content of absolute ethanol and formaldehyde is added, which is highly irritatin

Method used

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  • Liquid dressing and preparation method thereof
  • Liquid dressing and preparation method thereof
  • Liquid dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The present embodiment provides a liquid dressing, comprising the following components in parts by mass:

[0032] Film-forming agent Ⅰ: 5 parts of polyvinyl formal;

[0033] Film-forming agent Ⅱ: 2 parts of polyvinylpyrrolidone, 2 parts of polydimethylsiloxane;

[0034] Volatile solvent: 50 parts of ethanol;

[0035] Plasticizer: 0.5 part of triethyl citrate, 0.5 part of tributyl citrate;

[0036] Auxiliary: 2 parts of solid paraffin.

[0037] Method of preparing said liquid dressing:

[0038] (1) Add the volatile solvent to the liquid mixing tank, stir at 30°C and 700r / min for 10min, so that the solvent is evenly mixed;

[0039] (2) The temperature of the liquid mixing tank is raised to 40°C, and the stirring is continued at 700r / min, and the film-forming agent I is added to the solvent prepared in step (1), and mixed evenly;

[0040] (3) At 30°C and 700r / min, slowly add film-forming agent II to the mixed solution prepared in step (2), continue stirring at 1000r / m...

Embodiment 2

[0043] The present embodiment provides a liquid dressing, comprising the following components in parts by mass:

[0044] Film-forming agent Ⅰ: 5 parts of polyvinyl butyral;

[0045] Film-forming agent Ⅱ: 4 parts of ethyl cellulose, 2 parts of nitrocellulose, 2 parts of polyvinylpyrrolidone;

[0046] Volatile solvents: 10 parts of ethanol, 10 parts of isopropanol, 10 parts of polydimethylsiloxane, 5 parts of polyhexamethyldisiloxane, 5 parts of isooctane, 10 parts of acetone, and 5 parts of ether;

[0047] Plasticizer: 2 parts of triethyl citrate, 1 part of tributyl citrate, 1 part of isopropyl palmitate, 1 part of triacetin, 2 parts of dimethyl phthalate, phthalate 1 part of diethyl formate, 1 part of dibutyl phthalate, 1 part of dibutyl sebacate;

[0048] Softener: 2 parts of glycerin;

[0049] Auxiliary: 5 parts of liquid paraffin.

[0050] Method of preparing said liquid dressing:

[0051] (1) Add the volatile solvent to the liquid mixing tank, stir at 35°C and 600r / min ...

Embodiment 3

[0056] The present embodiment provides a liquid dressing, comprising the following components in parts by mass:

[0057] Film-forming agent Ⅰ: 10 parts of polyvinyl butyral;

[0058] Volatile solvent: 20 parts of ethanol, 40 parts of isopropanol, 20 parts of polyhexamethyldisiloxane;

[0059] Plasticizer: 5 parts of triethyl citrate;

[0060] Softener: 3 parts of glycerin;

[0061] Additives: 1 part of solid paraffin, 1 part of liquid paraffin.

[0062] Method of preparing said liquid dressing:

[0063] (1) Add the volatile solvent to the liquid mixing tank, stir at 20°C and 500r / min for 20min, so that the solvent is evenly mixed;

[0064] (2) The temperature of the liquid mixing tank is raised to 25°C, 600r / min is continuously stirred, and the film-forming agent I is added to the solvent prepared in step (1), and mixed evenly;

[0065] (3) Under the conditions of 20°C and 500r / min, add plasticizer, softener and additives in sequence to the mixed solution prepared in step...

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PUM

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Abstract

The invention belongs to the field of wound surface nursing, and particularly relates to a liquid dressing and a preparation method thereof. The liquid dressing comprises the following components in parts by weight: 5-12 parts of a film forming agent I, 0-8 parts of a film forming agent II, 50-90 parts of a volatile solvent and 1-10 parts of a plasticizer. The liquid dressing has the characteristics of safe components and comfortable skin feel, the preparation method of the liquid dressing is simple, the cost is low, and the liquid dressing is suitable for industrial application.

Description

technical field [0001] The invention belongs to the field of wound care, and in particular relates to a liquid dressing and a preparation method thereof. Background technique [0002] In daily life, superficial skin injuries are very common, including abrasions, scratches, scalds and burns. Traditional wound care products such as band-aids / gauze have disadvantages such as strong foreign body sensation, easy adhesion to the wound, and easy to fall off after being wet. [0003] In the 1960s, the wet healing theory pointed out that a humid environment can increase the migration speed of epidermal cells, making the wound healing time shorter than that of wound scabs in a dry environment; in addition, a humid environment can promote the interaction between cell growth factors and receptors. Combined, it is beneficial to maintain the activity of wound cells and promote wound healing. Based on the theory of moist healing, liquid dressings for superficial skin injuries have become...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0019A61L26/0023A61L26/0061C08L29/04C08L39/06C08L83/04C08L1/28
Inventor 阮潇潇
Owner SHAANXI BIO REGENERATIVE MEDICINE CO LTD
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