Contact lens care solution and preparation method

A contact lens and care solution technology, applied in chemical instruments and methods, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as dry eyes, corneal loss, inflammation, and eye injuries

Inactive Publication Date: 2020-08-11
BLOOMAGE BIOTECHNOLOGY CORP LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, contact lenses cannot be worn continuously for a long time, and must be removed for cleaning and disinfection every day
[0004] The basic function of contact lens care solution is to clean, disinfect and remove protein from contact lenses. Currently, most contact lens care solutions on the market contain disinfectant ingredients such as chlorhexidine and geramine, which are harmful to the eyes
In addition, the moisturizing function of the existing contact lens care solution is not enough, and the user is prone to dry eyes, corneal loss and inflammation after wearing it.

Method used

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  • Contact lens care solution and preparation method
  • Contact lens care solution and preparation method
  • Contact lens care solution and preparation method

Examples

Experimental program
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Effect test

preparation example Construction

[0121] The application also provides a preparation method of contact lens care solution, comprising the following steps:

[0122] Step 1: Add water for injection in the dissolving tank;

[0123] Step 2: Add the moisturizing agent into the dissolving tank while stirring, and stir until completely dissolved;

[0124] Step 3: Mix ectoine or ophthalmologically acceptable ectoine derivatives, surfactants, antibacterial agents, moisturizing agents, buffers, osmotic pressure regulators, and chelating agents, and then slowly add to In the dissolving tank, stir to make it all dissolve to obtain mixed solution 1;

[0125] Step 4: Using hydrochloric acid or sodium hydroxide to adjust the pH of the mixed solution 1 to obtain the mixed solution 2;

[0126] Step 5: The mixed solution in the dissolution tank is filtered, and the filtered liquid is a contact lens care solution.

[0127] In this application, the water in the dissolving tank is heated to 80-85°C before adding the moisturizin...

Embodiment 1

[0137] Add water for injection in the dissolving tank; the molecular weight is 1.3×10 6 Da and 0.3×10 6 Da sodium hyaluronate (1.3 x 10 6 Da and 0.3×10 6 The mass ratio of Da is 1:4) into the dissolution tank while stirring, and stir until completely dissolved; 0.01g ectoine, 0.01g poloxamer 407, 0.05g dipotassium glycyrrhizinate, 0.005g borate Buffer, 0.01g sodium chloride, and 0.001g EDTA-2Na are mixed evenly, then slowly added to the dissolution tank, stirred to make them all dissolve, and mixed solution 1 is obtained; the pH of the mixed solution 1 is adjusted to 7.2 with hydrochloric acid , Obtain mixed solution two; Mixed solution two in the described dissolving tank is filtered, and the liquid that obtains after filtering is contact lens care solution, and the osmotic pressure of described contact lens care solution is 290mOsm / L, and concrete parameter is as shown in table 1.

[0138] Embodiment 2-Example 9 and Comparative Example 1-Comparative Example 2 are differen...

Embodiment 10

[0139] The difference between Example 10 and Example 4 is that there is only one molecular weight of sodium hyaluronate in Example 10, and the specific parameters are shown in Table 1.

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Abstract

The invention discloses a contact lens care solution. The contact lens care solution comprises ectoin or an eye science acceptable ectoin derivative, a surfactant, an antibacterial agent, a humectant,a buffer agent, an osmotic pressure regulator and a chelating agent. The invention further provides a preparation method of the contact lens care solution. According to the contact lens care solutionprovided by the invention, the moisturizing and lubricating performance of contact lenses can be improved, the wearing comfort is improved, a repairing effect is achieved, and the phenomena of redness, swelling, inflammation and the like caused by long-term wearing of the contact lenses can be eliminated.

Description

technical field [0001] The present application relates to the technical field of contact lenses, in particular to a contact lens care solution and a preparation method. Background technique [0002] With the change of people's lifestyle and working conditions, people spend more and more time using their eyes, such as watching computers, watching TV, playing video games, etc., contact lenses not only improve myopia and hyperopia in terms of appearance and convenience. , astigmatism and other refractive error patients have brought great improvement, and has the advantages of large field of view, less image distortion, etc., more and more people choose to wear contact lenses. [0003] Contact lenses are exposed to an environment that is likely to be in contact with microorganisms when worn or stored, and have the disadvantages of easily becoming a breeding ground for microorganisms and being easily contaminated. Soft contact lenses are highly hydrophilic, and most of them are ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C11D1/72C11D3/22C11D3/28C11D3/04C11D3/33C11D3/32C11D3/30C11D3/48C11D3/60A61K31/505A61P27/02
CPCA61K31/505A61P27/02C11D1/722C11D3/046C11D3/221C11D3/227C11D3/28C11D3/30C11D3/323C11D3/33C11D3/48
Inventor 王静耿凤邵萌郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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