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Hydrogel antipyretic patch and preparation process thereof

A preparation process and technology of antipyretic paste, applied in the field of medicine, can solve the problems of slow heat transfer speed, insignificant heat absorption effect, and inappropriate use in large quantities, and achieve the effects of fast antipyretic speed, improved permeability and low cost

Inactive Publication Date: 2018-06-08
NANJING FANKANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cooling speed of the hydrogel antipyretic patch in the prior art is relatively slow, mainly because the macromolecule water-fixing effect of the hydrogel antipyretic patch is too strong, there are few evaporable water molecules, and the air permeability is not good, resulting in The heat transfer speed is slow, and the heat absorption effect is not significant
[0003] Also can add peppermint in the existing hydrogel patch as cooling agent, peppermint can produce cooling effect and property of medicine is not strong, can produce effect to the temperature sensor of human body, makes the feeling of giving coolness by cold sensor; But because of its Strong odor and strong irritation to skin, mucous membrane tissue and eyes, so it is not suitable to use in large quantities

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] A hydrogel antipyretic patch, comprising the following components by weight:

[0054] NP-700: 150 copies;

[0055] Glycerin: 650 parts;

[0056] Aluminum glycylate: 3 parts;

[0057] EDTA disodium salt: 2 parts;

[0058] PVPP: 20 copies;

[0059] CMC: 18 copies;

[0060] Purified water: 1600 parts;

[0061] PVP-K120: 160 copies;

[0062] Tartaric acid: 6 parts;

[0063] Bright blue: 0.006 parts;

[0064] Ethanol: 14 parts;

[0065] WS-23: 3 copies;

[0066] Ice flakes: 3 parts;

[0067] DMDMH: 6 servings.

Embodiment 2

[0069] NP-700: 150 copies;

[0070] Glycerin: 750 parts;

[0071] Aluminum glycylate: 4.5 parts;

[0072] EDTA disodium salt: 3 parts;

[0073] PVPP: 30 copies;

[0074] CMC: 21 copies;

[0075] Purified water: 1800 parts;

[0076] PVP-K120: 170 copies;

[0077] Tartaric acid: 8 parts;

[0078] Bright blue: 0.007 parts;

[0079] Ethanol: 18 parts;

[0080] WS-23: 6 copies;

[0081] Ice flakes: 6 parts;

[0082] DMDMH: 9 parts.

Embodiment 3

[0084] A hydrogel antipyretic patch, comprising the following components by weight:

[0085] NP-700: 150 copies;

[0086] Glycerin: 850 parts;

[0087] Aluminum glycylate: 6 parts;

[0088] EDTA disodium salt: 4 parts;

[0089] PVPP: 40 copies;

[0090] CMC: 24 copies;

[0091] Purified water: 2000 parts;

[0092] PVP-K120: 180 copies;

[0093] Tartaric acid: 10 parts;

[0094] Bright blue: 0.009 parts;

[0095] Ethanol: 22 parts;

[0096] WS-23: 9 copies;

[0097] Ice flakes: 9 parts;

[0098] DMDMH: 12 servings.

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PUM

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a hydrogel antipyretic patch and a preparation process thereof. The hydrogel antipyretic patch provided by the invention is made by using NP-700 as a hydrophilic polymer and then being supplemented with a gel polymer, a gel rate control agent, a preservative, a moisturizer, a pH (potential of Hydrogen) control agent, a thickener and a cooling compound; the hydrogel antipyretic patch is safe in component and quick in antipyretic speed, has no pungent smell, has a light aroma, and is high in use comfort degree; nerol added into the hydrogel antipyretic patch can be closely combined with a high-molecular skeleton due to a unique molecular structure, and is used for dispersing the adsorptive power, to a water molecule, of a high molecule; at a certain temperature, the permeability of hydrogel is ameliorated; the vaporized water molecule can be quickly diffused; the effect of quickly lowering a temperature is achieved; in addition; the fresh smell of the nerol can be also used for promoting the use feeling of the antipyretic patch; the process for preparing the hydrogel antipyretic patch, which is provided by the invention, is simple; the cost is low; the making procedure is nontoxic and pollution-free.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a hydrogel antipyretic patch and a preparation process thereof. Background technique [0002] As a material with high water absorption and high water retention, hydrogel can be used in physical cooling products for the human body; when the hydrogel patch is applied to the surface of the human body, sufficient water in the hydrogel vaporizes and absorbs heat to remove body heat, thereby reducing the body temperature . The hydrogel antipyretic patch in the prior art has a slow antipyretic speed, mainly because the polymer water-fixing effect of the hydrogel antipyretic patch is too strong, there are few evaporable water molecules, and the air permeability is not good, resulting in The heat transfer speed is slow, and the heat absorption effect is not significant. [0003] Mint can also be added as a cooling agent in the existing hydrogel patch. Mint can produce a cooling effect ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/32A61K47/38A61K47/10A61K47/18A61K31/045A61P29/00
CPCA61K9/7023A61K9/7061A61K31/045A61K47/10A61K47/18A61K47/32A61K47/38
Inventor 蔡金山
Owner NANJING FANKANG MEDICAL TECH
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