A polypeptide compound fertilizer mainly adopts an oil cake additive, rice bran, a mineral fertilizer and an insect decomposing additive as main components, also urea, egg shells, distiller's grains,fish bones and the like are added, and pond mud, photosynthetic bacteria, fish bone zinc gluconate and yeast are added. The component source is friendly to environment, green, cheap, and rich in nutrient. After the peptide compound fertilizer is applied to soil, the soil organic matter content is high, and the quality is relatively good, the content of compounds, ashy substances, cellulose and thelike is high, also the soil contains trace elements such as boron, zinc and molybdenum, and can provide comprehensive nutrition for crops, thereby increasing the yield of vegetables.