99results about How to "High efficiency load" patented technology

The invention discloses a block chain multi-node secure communication method for an industrial internet, and the method comprises the steps: constructing a multi-chain cooperation mechanism, and obtaining an inter-chain interaction path table; determining a task partition optimization scheme and inter-chain interaction path update data based on the inter-chain interaction path table; matching an adaptive node resource for each task according to a task partition optimization scheme; determining an encryption mechanism between a cross-chain protocol and a block chain according to the security requirement of the task; constructing a multi-level block chain node hierarchical architecture and an intra-chain and inter-chain communication architecture, and formulating a parallel communication scheduling scheme; formulating a dynamic load balancing strategy based on the node resource use condition and the task execution state; and obtaining the task execution progress and the resource use condition of each block chain node, and adjusting the task scheduling and cross-chain communication path. Through the multi-dimensional collaborative design, the execution efficiency, the resource utilization rate and the communication security of the industrial internet are remarkably improved, and the stability and the reliability in a complex multi-chain collaborative scene are ensured.

The invention discloses a hydrogel compound, a preparation method and application, and belongs to the technical field of hydrogel. The hydrogel compound provided by the invention is prepared from the following raw materials: a hydrogel matrix, sodium glycerophosphate pentahydrate and a functional drug, the hydrogel matrix is prepared from chitosan, hydroxybutyl chitosan and methacrylated gelatin; the functional medicines comprise cannabidiol, tobramycin and acetylsalicylic acid; the hydrogel compound provided by the invention has excellent mechanical properties and water vapor permeability, also has excellent slow release property and wound healing ability, and can be widely applied to preparation of medicines for treating wounds. In addition, the preparation method of the hydrogel compound provided by the invention is simple to operate and beneficial to practical application.

The embodiment of the invention provides an embolism microsphere capable of loading platinum drugs, a drug-loaded embolism microsphere and a preparation method, and relates to the technical field of medical instruments. The structural main chain of the embolism microsphere capable of loading the platinum medicine contains adjacent carboxyl groups, and the two adjacent carboxyl groups and platinum ions in the platinum medicine can form an annular structure. The embolism microsphere provided by the embodiment of the invention can be used for efficiently loading platinum drugs.

The invention discloses a high-definition video signal transmission system based on optical signals, relates to the technical field of video signal transmission, and solves the problems that video signals are difficult to reasonably divide, and meanwhile, signal transmission is difficult to manage and distribute in a video stream signal transmission process. And stable and safe transmission of high-definition video signals is inconvenient to guarantee. Comprising a central node, an optical fiber network and a plurality of video transmission nodes, a video signal is divided into a plurality of independent video streams, so that flexible allocation according to network bandwidth and node performance is facilitated, and the overall transmission efficiency is improved; the compressed independent video stream can be transmitted more quickly through a network, so that the waiting time of a data packet is shortened, and the overall delay is reduced; different video streams can be dynamically distributed to different optical fibers according to actual requirements, so that more efficient resource utilization and load balancing are realized.

The invention discloses preparation and application of a biological material for targeted therapy of osteoarthritis, and the preparation method comprises the following steps: according to a phage screening principle, after phages are combined with cartilage cells, washing off phages which are not combined with the cartilage cells, are not firmly combined with the cartilage cells and are non-specifically combined with the cartilage cells; eluting the specifically bound bacteriophage with glycine acid; after the specific binding bacteriophage is amplified by escherichia coli, screening is carried out by utilizing a bacteriophage display technology and cartilage cells; the preparation method comprises the following steps: preparing a small-size porous microgel loaded drug by adopting a multiple Pickering emulsion template method; and grafting the screened cartilage targeting peptide to the surface of the porous hydrogel microsphere to obtain the HS-SP microsphere. According to the invention, the problem of OA targeting can be effectively solved by adopting a phage display technology, and a drug is precisely targeted and delivered to an OA lesion region; the porous hydrogel microspheres with small particle size are prepared by adopting a multiple Pickering emulsion method, so that the use of a large number of surfactants is avoided, and the efficient loading and release of drugs can be realized.

The invention relates to the technical field of biological medicine materials, and provides a preparation method and application of biological polysaccharide macromolecule polymerization coated PQQ, a polysaccharide macromolecule slow-release skeleton carrier used for coating in the method comprises konjac glucomannan and chitosan, the carrier can form a honeycomb net structure, PQQ can be embedded into the net structure, and the PQQ can be embedded into the honeycomb net structure. The coated PQQ has a slow release function in the intestinal environment, the three-dimensional honeycomb structure can be extended under the intestinal environment condition, the PQQ is slowly released, and more than 90% of the PQQ is released within 8 hours.

The invention discloses an intelligent dynamic load balancing method and system based on Clico-VPP. The method comprises the following steps: acquiring a load state index of a back-end service pod; according to the load state index and a service capability coefficient corresponding to the back-end service pod, calculating a dynamic traffic allocation weight of the back-end service pod through a weighted calculation model; based on a dynamic threshold synchronization strategy, synchronizing the state of a first hash ring located in a control plane to a second hash ring located in a forwarding plane; and based on the second hash ring, determining a target pod for the input data stream through consistency lookup. A double-loop decoupling architecture is provided, hash rings of a control plane and a forwarding plane are separated, a synchronization strategy is determined through a dynamic threshold value, decision intelligence and forwarding stability are both considered, and jitter is avoided; meanwhile, a dynamic weight-driven consistent Hash algorithm is adopted, a real-time load index and Pod service capability are fused to calculate a dynamic weight, and the dynamic weight is mapped into the number of virtual nodes, so that intelligent scheduling based on capability and maximum maintenance of connection during capacity expansion and contraction are realized.

The invention relates to the technical field of fiber acid dyeing, and particularly discloses a sheep villus fiber acid dyeing fixation method which comprises the following steps: mixing acetic acid, triethanolamine and cardanol polyoxyethylene (n) ether sulfate to obtain a prefabricated material a; caprolactam is mixed with rhamnolipid, polyvinylpyrrolidone and acylation modified chitosan, and a prefabricated material b is obtained; mesoporous silica, saturated ammonia water, tetraethoxysilane, potassium methoxide, dioxane and succinic anhydride are adopted to prepare a prefabricated material c; adding the prefabricated material a into the prefabricated material b, stirring, then adding the prefabricated material c, uniformly mixing, adjusting the pH value of the system to 5-6, adding cashmere fibers, keeping the temperature at 5-10 DEG C for 10-20 minutes, heating to 40-50 DEG C, keeping the temperature for 10-20 minutes, adding an acid dye and anhydrous sodium sulfate, uniformly stirring, keeping the temperature for 1-2 hours, heating to 80-90 DEG C, keeping the temperature for 30-50 minutes, taking out, washing, and airing at room temperature.

The invention provides a distributed Internet of Things simulation system based on time synchronization, event driving and a message bus, and the system comprises a simulation model which is used for simulating different types of Internet of Things equipment or communication entities; the model management system is used for managing and controlling the life cycle, configuration and version management of the simulation model so as to ensure that the system adds, deletes or modifies different simulation models; the time synchronizer is used for ensuring that all nodes in distributed simulation keep a unified time reference so as to ensure the sequence and synchronous execution of events; the message bus is used for transmitting messages, events and data among the simulation nodes so as to ensure real-time communication and cooperation of each unit in the distributed system; and the front-end interface is used for monitoring a simulation process, operating equipment and checking simulation data in real time. According to the invention, the problem of low operation and maintenance efficiency of Internet of Things simulation software in the prior art can be solved.

The invention discloses an iron-based MOFs composite electrode and application thereof. The preparation method comprises the following steps: firstly preparing Cu-coated Fe-ZIF powder in a coprecipitation manner, then preparing Fe2O3-coated Cu-coated Fe-ZIF powder by a hydrothermal reaction, step-by-step ultrasonic and vacuum arc method, and then fusing with S at high temperature by a hot melting method; and preparing the active material Fe2O3 (at) Cu (at) Fe-ZIF (at) S for the iron-based MOFs composite electrode. The Fe-ZIF material is selected as a metal frame to coat the surface of Cu, the Fe-ZIF material and Fe oxide are mixed, calcined and subjected to a direct-current vacuum arc method to synthesize the wooden-stick-shaped nanosphere particles, the defect concentration in a Fe2O3 structure can be effectively increased under the synergistic effect of the advantages of Cu-coated Fe-ZIF components, more loading space is provided for subsequent components such as sulfur, and the Fe-coated Fe-ZIF composite material has a good application prospect. The sulfur loading effect is improved, the sulfur utilization rate is improved, the volume change is relieved, and the battery performance is further improved.

The invention discloses self-adaptive drug-loading hydrogel as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials.According to the self-adaptive drug-loading hydrogel, formylated gamma-cyclodextrin, sodium hyaluronate grafted coumarin and sodium hyaluronate grafted adipic dihydrazide are used as carrier raw materials; an antibacterial agent and an insulin substance are loaded on a carrier, and the self-adaptive drug-loading hydrogel is prepared through the host-guest complexing effect of gamma-cyclodextrin and coumarin and the series connection effect of an aldehyde group of aldehyded gamma-cyclodextrin and a hydrazone bond of a hydrazide group of sodium hyaluronate grafted adipic dihydrazide. The self-adaptive hydrogel-loaded hydrogel not only can rearrange a gel network and effectively fill and match a wound surface with a complex shape, but also can release levofloxacin and insulin on the wound surface in a long-acting manner to play roles in inhibiting bacterial infection, promoting endothelial cell proliferation, angiogenesis, collagen deposition and the like; therefore, the healing process of diabetes infected wounds is obviously accelerated.

The invention belongs to the technical field of chemistry, and particularly relates to a water-based stable transdermal preparation based on a structural nanoemulsion and a preparation method of the water-based stable transdermal preparation. 1% to 10% of a polyether block copolymer; 5%-20% of a co-emulsion; 0.1% to 15% of an active ingredient; and the balance of deionized water. Through a compounding system of an amino acid surfactant and a gemini surfactant and in combination with the synergistic effect of a specific polyether block copolymer, a nanoemulsion drug delivery system with a stable structure is constructed. Through a compound system of the amino acid surfactant and the gemini surfactant and by combining the synergistic effect of the polyether block copolymer, a nano-emulsion drug delivery system with a stable structure is constructed, and the nano-emulsion drug delivery system has good long-term storage stability and temperature adaptability, is not easy to layer and is uniform in particle size distribution.

The invention discloses a multifunctional nano-composite as well as a preparation method and application thereof. The multifunctional nano-composite comprises a DNA carrier, a photothermal agent and an anti-tumor drug, the DNA carrier comprises a long DNA single chain with n repetitive units, n DNA complementary single chains, n aptamer chains with cancer cell targeting capability and n SH-DNA chains connected with photo-thermal agent nanoparticles, wherein n is an integer between 5 and 150; each repetitive unit of the long DNA single chain has 63 basic groups, and the basic groups in each repetitive unit are respectively paired and connected with the DNA complementary single chain, the aptamer chain and the SH-DNA chain. According to the invention, the aptamer with multivalent targeting capability and a large amount of photothermal agents and chemotherapeutic drugs are loaded by utilizing a multi-repetitive unit of the long DNA single-chain carrier, so that a chemotherapy / photothermal / chemical power synergistic treatment system with multivalent aptamer positioning is constructed, and cancer cells can be effectively killed.

The invention discloses a component optimization method for preparing a liquid fertilizer from acetylisovaleryltylosin tartrate waste liquid, and relates to the technical field of fertilizer preparation, and the component optimization method comprises the following specific steps: step 1, selecting nanoscale activated carbon with the specific surface area of 1000m < 2 > / g-1500m < 2 > / g as a base material, the method has the advantages that a microbial flora system is constructed by screening out pseudomonas bacteria, actinomycetes and bacillus, and the pseudomonas bacteria can effectively decompose complex organic pollutants in the waste liquid by virtue of the mineralization effect of the pseudomonas bacteria and gradually convert the complex organic pollutants into carbon dioxide, water and simple organic acid, so that the primary purification of the waste liquid is realized; actinomycetes can utilize secreted enzymes to convert acetylisovaleryltylosin tartrate into small molecule compounds containing nitrogen, phosphorus, potassium and other nutrient elements, bacillus further promotes synthesis and stability of the nutrient small molecules, it is ensured that the liquid fertilizer is comprehensive in nutrient and accurate in content, the plant growth requirement can be better met, and the liquid fertilizer has a good application prospect. The resource utilization rate of the acetylisovaleryltylosin tartrate waste liquid is greatly improved.

This invention relates to a biomass char composite electrocatalyst supported on nickel-cobalt sulfides, its preparation, and its application. The preparation method includes: subjecting biomass material to high-temperature carbonization to obtain a biomass char substrate with a porous structure; immersing the biomass char substrate in a solution containing nickel and cobalt salts, and obtaining biomass char supported on nickel-cobalt oxides through a hydrothermal reaction; placing the biomass char supported on nickel-cobalt oxides in a solution containing a sulfur source, and obtaining the biomass char composite electrocatalyst supported on nickel-cobalt sulfides through a hydrothermal reaction. The biomass char composite electrocatalyst supported on nickel-cobalt sulfides of this invention can be applied in biomass electrocatalytic oxidation reactions, achieving selective control of the biomass oxidation reaction and oxygen evolution reaction through an external magnetic field, thereby improving the efficiency of high-value conversion of biomass. The magnetic field control method of this invention has advantages such as non-contact control, simple system, and strong applicability, and has good application prospects.

This invention discloses a nanoRNA delivery system and its application in the control of Sclerotinia sclerotinia disease, relating to the field of biotechnology. The preparation method of the nanoRNA delivery system includes the following steps: mixing chitosan, sucrose, and aspartic acid uniformly and then subjecting them to a hydrothermal reaction to obtain a quantum dot-chitosan degradation product complex; mixing the quantum dot-chitosan degradation product complex with double-stranded RNA to obtain the nanoRNA delivery system; the double-stranded RNA is used to silence Sclerotinia sclerotinia virulence-related transcription factor genes. The nanoRNA delivery system provided by this invention can effectively protect RNA and exhibits a very high inhibitory effect on Sclerotinia sclerotinia in plants, providing a novel technical solution for the green and precise control of Sclerotinia sclerotinia disease.

The invention relates to the technical field of image transmission, in particular to an energy consumption self-adaptive management method and system of a wireless image transmission module. Comprising the steps of obtaining operation data of at least one node, and analyzing a network load to adjust interaction frequency configuration; load balancing parameters are determined according to interaction frequency configuration, transmission task priorities are dynamically adjusted, node energy consumption data are collected, and resource waste points are checked to update an energy consumption distribution scheme; predicting the traffic of a transmission path according to an energy consumption distribution scheme, optimizing path allocation and reallocating resources when the traffic is greater than a set value, and updating node state shared data; and finally, the network operation state is calibrated according to the node state shared data, and energy consumption optimization configuration is obtained, so that energy consumption is reduced, and network efficiency is improved. According to the invention, the problem that the energy consumption management of the wireless image transmission network is difficult to finely regulate and control along with the load change is solved, and the self-adaptive energy conservation and stable transmission of the distributed image transmission module are realized.

The application discloses a multifunctional antibacterial coating bone implant device based on a selective vacuum perfusion process and a preparation method thereof. The method comprises the following steps: 1) pretreating a titanium alloy base; 2) performing anodic oxidation treatment on the pretreated titanium alloy base to construct a nanotube structure on the surface of the titanium alloy base; 3) selectively coating the treated titanium alloy base with a hydrogel adhesive, then immersing the titanium alloy base in a povidone iodine mixed solution to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a bone growth promoting factor to perform vacuum perfusion, and performing post-treatment, then again performing selective coating, immersing the titanium alloy base in a solution containing a blood vessel growth promoting factor to perform vacuum perfusion, and performing post-treatment; and 4) encapsulating the obtained sample surface with an in-situ self-polymerized polydopamine layer, washing and freeze-drying. The bone implant device has antibacterial, bone growth promoting and blood vessel growth promoting functions, and can greatly improve the curative effect on bone fracture symptoms accompanied by infection.

The invention discloses an iron-carbon catalytic material based on coal gasification slag as well as a preparation method and application of the iron-carbon catalytic material, and belongs to the technical field of industrial solid waste recycling. The preparation method comprises the following steps: adding dried coal gasification slag into an oxalic acid solution for extraction to obtain a suspension A; adding a reducing agent into the suspension A, carrying out precipitation reaction, and then carrying out solid-liquid separation to obtain a solid B; and sintering the solid B to obtain the composite material. The invention further discloses the iron-carbon catalytic material based on the coal gasification slag prepared by the method and application of the iron-carbon catalytic material. According to the method, the industrial solid waste coal gasification slag is used as a carrier, endogenous iron in the coal gasification slag is converted by adopting an acid leaching-reduction precipitation-roasting method, the iron-supported catalytic material with a stable structure and excellent performance is obtained, the process is green, the cost is low, the organic wastewater treatment capacity is excellent, and the practical value is relatively good.

The invention relates to the technical field of artificial intelligence, in particular to an AI-based intelligent calculation platform management method. The method comprises the following steps: S1, receiving target data and carrying out segmentation processing; s2, adjusting a preset character length; step S3, storing the segmented real-time target segments on different database nodes according to the change curve; and S4, analyzing the demand of the database node, and classifying the current transmission network according to an analysis result. By flexibly adjusting the length of the preset character, segmentation and processing of the data can better adapt to actual access requirements, so that the efficiency and accuracy of data processing are improved, storage resources are reasonably distributed on different database nodes, the storage layout is optimized, the speed of data retrieval and processing is improved, and the data retrieval and processing efficiency is improved. Through demand analysis and network classification of database nodes, resources are reasonably allocated, redundancy is reduced, and it is ensured that the system is kept efficient when facing different data loads.

The invention relates to the technical field of aerogel microsphere preparation, in particular to a method for preparing composite nanocellulose aerogel microspheres based on electrostatic field auxiliary regulation and control. Comprising the following steps: forming uniform liquid drops from a silane modified nano cellulose suspension through an electrostatic spraying device provided with an annular electrode group and a real-time monitoring feedback system; the liquid drops are induced by an electrostatic field in a pre-cooling area to be initially set and then subjected to liquid nitrogen cryogenic treatment, gradient freeze drying is conducted, and aerogel microspheres are obtained; and finally, carrying out surface modification on the aerogel microspheres, and loading nano microspheres under the assistance of an alternating electric field to obtain the composite nano cellulose aerogel microspheres. Through the synergistic effect of the multi-stage electric field, accurate regulation and control on the whole process of microsphere forming, internal structure construction and functional compounding are realized, so that the composite nanocellulose aerogel microspheres with narrow particle size distribution, uniform size and adjustable functions are prepared, and the composite nanocellulose aerogel microspheres have wide application prospects in the fields of adsorption, catalysis, biological medicine and the like.

The application discloses a preparation method and equipment of a chlorin supermolecular assembly, and belongs to the technical field of functional nanomaterials. The Y+S composite microfluidic chip is designed, the nucleation and growth kinetics of Ce6 molecules are precisely controlled by using the Dean vortex flow induced by the S-shaped flow channel, directional preparation of the nanospherical Ce6 supermolecular assembly is realized, and meanwhile, the assembly has a narrow particle size distribution (PDI<0.1), and the problems of great morphology heterogeneity and poor controllability of the traditional method are completely solved, thereby providing technical support for the morphology standardized preparation of the Ce6-based nanodelivery system.

The application discloses an LDH-based vaccine adjuvant and a preparation method and application thereof, and belongs to the technical field of aluminum adjuvant preparation of vaccines, and the preparation method comprises the following steps: mixing at least one of soluble magnesium salt, soluble zinc salt, soluble manganese salt and soluble calcium salt with soluble aluminum salt, and then performing a co-precipitation reaction with a sodium hydroxide aqueous solution in a colloid mill device, and performing crystallization to obtain LDH nanosheets; dispersing the LDH nanosheets in a PBS solution, adding a hepatitis B surface antigen molecule drug, uniformly mixing, and then performing centrifugation to obtain the LDH-based vaccine adjuvant. The LDH-based vaccine adjuvant can significantly promote the maturation of DC cells and the activation of T cells, and the total IgG level reflects the overall humoral immune response intensity of the body to vaccines or pathogens; the LDH-based vaccine adjuvant forms a "storage library" at an injection site to store antigens and slowly release the antigens, and the purpose of long-time continuous stimulation of the immune system in the body is achieved.

The present invention provides a ready-to-use mesoporous mineralized silk fibroin microsphere and a preparation method and application thereof. SilMA hydrogel microspheres are prepared by a photocrosslinking oil / water emulsification method, and then dry mesoporous mineralized SilMA microspheres (mSilMA for short) are prepared by combining biomimetic mineralization with a critical point drying method. Silk fibroin materials that are not easily degraded and have good biocompatibility are selected as carriers to solve the problems of easy loss and inability to retain BMP-2 for a long time; biomimetic mineralization forms a calcium phosphate coating to achieve efficient loading and controlled release of BMP-2; critical point drying forms a mesoporous structure, which is conducive to drug loading and release. mSilMA is applied to BMP-2 loading and controlled release, with high protein loading efficiency and long-term low-volume sustained release. The present invention has simple ingredients, mild preparation conditions, and is easy to obtain, providing a new approach for bone defect repair and has broad clinical application prospects.

The invention provides a load balancing-oriented cell switching method, device and equipment and a storage medium, and belongs to the technical field of communication, and the method comprises the steps: constructing a load distribution diagram by using neighbor cell nodes determined based on candidate neighbor cells of a current cell and user nodes determined based on transfer users connected with the current cell; each edge of the load distribution diagram is used for associating a neighbor cell node and a user node; utilizing an edge weight prediction model to predict the edge weight of each edge in the load distribution diagram to obtain a load distribution diagram after the edge weight is updated; and determining a target cell switched by the transfer user based on the load distribution diagram after the edge weight is updated. According to the load balancing-oriented cell switching method, device and equipment and the storage medium provided by the invention, the load balancing problem is converted into the edge prediction problem of the heterogeneous bipartite graph, the topological structure information of a communication network can be fully utilized, the target cell most suitable for switching can be accurately matched for a user, and the user experience is improved. Therefore, the optimal load balancing among the cells is realized.

The invention discloses a targeted nano photosensitizer carrier and a preparation method and application thereof, and relates to the technical field of photosensitizer carriers, the preparation method of the targeted nano photosensitizer carrier comprises the following steps: activating 4-carboxyphenylboronic acid, dropwise adding the activated 4-carboxyphenylboronic acid into a methanol solution of polyethyleneimine, and reacting to obtain phenylboronic acid modified polyethyleneimine; dissolving the polyethyleneimine into a phosphate buffer solution, dropwise adding a methanol solution of 1, 2, 4-trihydroxy anthraquinone, and reacting in a dark place to obtain anthraquinone-boric acid ester modified polyethyleneimine; and activating and reacting with a folic acid solution to obtain the folic acid. The prepared targeted nano photosensitizer carrier can stably load a photosensitizer containing an aromatic ring structure, realizes light-controlled release and pH response, can specifically recognize tumor cells with high folate receptor expression, and has a wide application prospect in the field of photodynamic therapy.

The invention belongs to the technical field of multiple sclerosis, and particularly relates to a tolerogen vaccine microneedle patch for multiple sclerosis, the tolerogen vaccine microneedle patch for multiple sclerosis comprises methacryloyl gelatin and zeolite imidazole skeleton-8 for encapsulating tolerogen polypeptides, the tolerogen polypeptides are encapsulated by using the large aperture and extremely high specific surface area of ZIF-8 nanoparticles, and the tolerogen vaccine microneedle patch for multiple sclerosis is prepared from the methacryloyl gelatin and the zeolite imidazole skeleton-8 for encapsulating the tolerogen polypeptides. According to the preparation method, efficient loading of a polypeptide drug is achieved, meanwhile, rapid crystallization of nanoparticles can prevent degradation of polypeptide and is beneficial to tolerating slow release of original polypeptide, the adopted GelMA hydrogel microneedle has enough mechanical strength, can penetrate through skin cuticle and form a diffusion channel beneficial to release of the polypeptide drug, and controllable slow release of the polypeptide drug in skin tissue can be achieved. The GelMA hydrogel microneedle drug release device can directly penetrate through the skin cuticle to deliver the polypeptide drug to the corium layer, so that the sustained and controlled release of the tolerance original polypeptide in the skin tissue is realized, the first-pass effect of the liver is avoided, and the treatment purpose is realized by inducing immune tolerance.

The embodiment of the invention provides a resource dynamic scheduling method and electronic equipment. According to the embodiment of the invention, in a network scene containing at least two NAS nodes, the load evaluation indexes associated with the resources under the tenant instance dimension and the node dimension are introduced for dynamic scheduling of the tenant instances on the NAS nodes, such as creating a copy instance on the target NAS node. According to the method and the device, a tenant instance and a copy instance corresponding to the tenant instance are enabled to process IO requests issued by clients butted with the tenant instance according to a load balancing principle, so that the overall resource utilization rate of a network scene can be effectively improved, the problem of non-uniform load of each NAS node is reduced, the processing efficiency of the IO requests is improved, and the user experience is improved. Therefore, efficient utilization and load balancing of overall resources are realized, and high availability and stability of a network scene are improved.

The invention relates to the technical field of small molecule bonding drugs, in particular to an activated type methylene blue bonding drug which comprises an adriamycin-methylene blue bonding drug DOX-MB and a 1-methyl-tryptophan-methylene blue bonding drug MT-MB. Two bonding drugs DOX-MB or MT-MB based on methylene blue are designed and synthesized, MT or DOX is bonded with methylene blue through urea bonds, and the synthesis method is simple and easy to implement; the two bonding drugs DOX-MB or MT-MB and the distearoyl phosphatidyl ethanolamine-polyethylene glycol are assembled in an aqueous solution to form the nano-drug, so that efficient loading of DOX or MT can be realized; the bonding drug DOX-MB or MT-MB has no cytotoxicity, and singlet oxygen generated by methylene blue under near-infrared laser irradiation or ultrasonic conditions can break urea bonds to release a parent drug, so that precise and controllable release and combined treatment of the drug are realized; the fluorescence of methylene blue in the bonding drug DOX-MB or MT-MB is quenched, and the methylene blue fluorescence released by urea bond breakage under near-infrared laser irradiation or ultrasonic conditions is recovered, so that the method can be used for real-time detection of drug release.

The invention relates to an electrochemiluminescence sensor based on an intelligent controlled release-interface capture-self-enhancement mechanism and application of the electrochemiluminescence sensor in procalcitonin detection, and belongs to the technical field of electrochemiluminescence detection. Controllable release of signal molecules is achieved by packaging terpyridyl ruthenium through ZIF-8, meanwhile, a DNA layer rich in guanine is modified on an electrode interface, and the layer can serve as a nano trap to efficiently capture the signal molecules and can also serve as a co-reactant to achieve signal amplification. A DNA strand displacement reaction is utilized to regulate and control a target response release process, and detection is realized according to a quantitative relationship between the concentration of procalcitonin and an electrochemical luminescence signal. A labeling recovery method verifies that the recovery rate of the sensor in a human serum sample reaches 100.6-103.6%, good accuracy and precision are shown, and a reliable platform is provided for clinical detection of inflammatory markers.