7results about How to "Improve load effect" patented technology

This invention discloses a method for preparing resveratrol-loaded whey protein amyloid fibers based on moderate electric field modification. The method involves pretreating whey protein using a moderate electric field non-thermal effect, forming amyloid fibers through acid-thermal treatment, and further constructing a resveratrol delivery system based on protein fibrils. The resulting whey protein fiber-resveratrol complex exhibits excellent loading performance, antioxidant activity, and bioavailability, providing an effective carrier construction strategy for the efficient delivery and stabilization of hydrophobic and environmentally sensitive active molecules. This invention reveals the regulatory mechanism of the moderate-intensity electric field non-thermal effect in the protein fibrillation process, providing new technical ideas and theoretical references for the precise design of protein fiber structures and the development of functional protein-based delivery carriers, and providing technical support for the green preparation of protein fibrils and their in-depth development in functional foods.

The application relates to the technical field of drug delivery, in particular to a ZIF-8 / PDA composite material and a preparation method and application thereof. The ZIF-8 / PDA composite material provided by the application has good feasibility in terms of loading and delivering curcumin. The ZIF-8 material is modified by polydopamine, and the loading effect of the ZIF-8 material as a carrier on drugs is improved. The characterization results show that the drug loading performance of ZIF-8@PDA is obviously improved. The in-vitro release experiment results show that CuR@ZIF-8@PDA has more significant pH response drug release characteristics, shows good inhibition on Staphylococcus aureus and Escherichia coli, the hemolysis rate is 3.1%, is within a safe range, the inhibition on HepG2 cells is stronger than that of CuR@ZIF-8, and more obvious oxidative stress reaction and cell apoptosis can be induced.

The utility model discloses a transverse driving device suitable for a needle plate of a flat knitting machine. The transverse driving device comprises a motor, a rocker arm, a left sliding rod, a right sliding rod, at least one left limiting hole and at least one right limiting hole, an output shaft of the motor is connected with a first end of a rocker arm, the axial direction of the output shaft is perpendicular to the length direction of the rocker arm, a second end of the rocker arm is connected with a right sliding rod, the right sliding rod is connected with the right part of the needle plate, and the length directions of the right sliding rod and the rocker arm are parallel to the base plane of the needle plate; the right limiting hole is formed in the horizontal direction, the right sliding rod penetrates through the right limiting hole to be connected with the right portion of the needle plate, and the right sliding rod can only do transverse reciprocating motion in the width range of the right limiting hole in the vertical direction. The left limiting hole is formed in the horizontal direction, the left sliding rod penetrates through the left limiting hole to be connected with the left portion of the needle plate, the left sliding rod can only do transverse back-and-forth movement in the width range of the left limiting hole in the vertical direction, the working requirement for transverse high-speed back-and-forth movement of the needle plate is met, and stability is achieved. The utility model further discloses the flat knitting machine comprising the transverse driving device.

The present application belongs to the technical field of biomaterial surface modification, and particularly relates to a multi-level micro-nano structure mixed phase titanate hydrogen release coating and a preparation method and application thereof. Nanometer titanium oxide and calcium carbonate are used as raw materials, and the two are uniformly mixed through a mechanical ball milling method. PVA is added for bonding and granulation, grinding and sieving to obtain a powder that can be sprayed. First, an initial coating containing titanium / calcium is prepared on a pure titanium substrate through plasma spraying, and the prepared coating is subjected to alkaline hydrothermal treatment to in-situ grow a mixed phase titanate micro-nano sheet structure. On this basis, the coating is further subjected to wet steaming treatment to destroy and reduce the micro-nano sheet, and in-situ induce the growth of dense secondary nano particles on the surface of the micro-nano sheet, so that the coating has better ammonia borane loading capacity, realizes stable and long-acting hydrogen release for more than 15 days, can effectively eliminate oxidative stress in a complex environment, and has excellent biocompatibility.

The invention discloses a method for repairing damage of high-dose gallic acid to the performance of myofibrillar protein gel based on a beta-cyclodextrin metal organic framework. Extracting myofibrillar protein; the preparation method comprises the following steps: preparing a beta-cyclodextrin metal organic framework by taking beta-cyclodextrin and potassium ions as raw materials; mixing the gallic acid solution with the beta-cyclodextrin metal organic framework solution to obtain a gallic acid / beta-cyclodextrin metal organic framework inclusion compound solution; then adding myofibrillar protein for homogenization, then adding a Fenton oxidation system, uniformly mixing and reacting; and heating the reacted myofibrillar protein in a water bath, and cooling to obtain the performance-repaired myofibrillar protein gel based on the beta-cyclodextrin metal organic framework encapsulated gallic acid. The gallic acid is encapsulated by the beta-cyclodextrin metal organic framework, so that excessive aggregation of myofibrillar protein caused by high-dose gallic acid is reduced, more proteins are promoted to participate in formation of an ordered gel network structure, and the myofibrillar protein gel with higher gel strength and water binding capacity is obtained.

The utility model discloses a kind of elevators with horizontal conveying, it is related to elevator technical field, including mobile frame, lifting platform is equipped in mobile frame, the inside one side of mobile frame is fixed with the lifting drive mechanism for driving lifting platform lifting, lifting drive mechanism includes lifting support base, sliding slot is equipped in the both sides of lifting support base, lifting seat is slidably connected in sliding slot, lifting seat is fixedly arranged on lifting platform, screw rod is threadedly connected on lifting seat, conveying belt is equipped on lifting platform, first sliding support assembly and second sliding support assembly are equipped between the four corners of lifting platform and mobile frame.The utility model structure is light, conveniently layout on production line, adopt unique lifting frame, so that it has better load capacity, by setting multiple sliding support assembly makes it have better stability in lifting process, can improve the arrangement efficiency of elevator on production line and the conveying efficiency to product.

The application discloses a method for optimizing PIP stacked capacitors in an ETOX Flash, the PIP stacked capacitors are integrated in the Flash, and an active region of the PIP stacked capacitors is a plurality of comb-shaped strips arranged in a row; a first plate of the PIP stacked capacitors is formed by a floating gate polysilicon of a PIP stacked capacitor region, and an active region below an outgoing end of the first plate is kept in a block shape and is combined; the first plate of the PIP stacked capacitors formed by the floating gate polysilicon is arranged alternately with STIs and has a height difference, and a plurality of STIs isolate the floating gate polysilicon to form a plurality of parallel strip arrangements; a 3D appearance in a wave type fluctuation of a second dielectric layer serving as a capacitor dielectric layer increases a surface area of the second dielectric layer in a limited horizontal projection area, and increases a capacitance; above the second dielectric layer is a part of a second plate formed by a control gate polysilicon, which is connected with the active region of the PIP stacked capacitor region through an interconnection structure, and forms the second plate of the PIP stacked capacitors together; and the first dielectric layer is between the floating gate polysilicon of the PIP stacked capacitor region and the active region.