102 results about "Saflufenacil" patented technology

The present invention relates to a method for post-emergent weed control, which comprises applying an effective amount of a composition comprising herbicide A (component A) and saflufenacil (component B) to emerged weeds, or an area, where weeds are growing.

The present invention relates to a method for post-emergent weed control, which comprises applying an effective amount of a composition comprising herbicide A (component A), trifludimoxazin (component B) and optionally saflufenacil (component C) to emerged weeds, or an area, where weeds are growing.

The present disclosure relates to herbicidal combinations, compositions and methods for controlling weeds comprising the carbamate herbicide asulam and an additional herbicide selected from the group comprising cyclohexanedione oxime herbicides, pyrimidinylsulfonyhirea herbicides, triazolopyrimidine herbicides, imidazolinone herbicides, alkylazine herbicides, triketone herbicides, N-phenylimide herbicides or chloroacetamide herbicides. Specifically, the additional herbicide may be one of clethodim, chlorimuron, diclosulam, imazamox, imazethapyr, indaziflam, mesotrione, saflufenacil, tiafenacil or S-metolachlor.

The invention relates to the technical field of emulsion in water, in particular to a saflufenacil-containing emulsion in water and a preparation method thereof. The saflufenacil suspending agent is prepared from the following raw materials in percentage by mass: 5-30% of saflufenacil, 10-40% of a solvent, 3-5% of an emulsifier, 3-5% of an anti-freezing agent, 0.01-0.1% of a defoaming agent, 0.1-1% of a stabilizer and the balance of water. The water emulsion containing the saflufenacil provided by the invention has good high-temperature storage stability, the decomposition rate of the saflufenacil is less than 5%, and the shelf life of 2 years is met; the dispersing and diluting properties in water with different hardness are good; the anti-flying agent is simply mixed with other dosage form products for use before flying prevention, the barrel mixing compatibility is good, and the abnormal problems of flocculation, layering and the like are not prone to occurring.

According to the herbicide composition and the application thereof, saflufenacil, pendimethalin and prometryn are scientifically proportioned and combined for the first time, due to the innovative matching, not only is the advantage complementation of herbicides achieved, but also the weeding effect is remarkably enhanced, the synergistic effect is obvious, the lasting period is long, and the herbicide composition has a good application prospect. The herbicide composition provided by the invention has an excellent control effect on field malignant weeds such as solanum nigrum and chenopodium album, and makes up for the defects and limitation of use of a single agent. Besides, the herbicide composition disclosed by the invention has high safety to important crops such as corn, cotton, soybeans, peanuts and the like, and does not damage the crops even in a compound planting mode, so that the problem that proper herbicide selection is lacked in the compound planting mode for a long time is successfully solved; powerful support is provided for promoting the sustainable development of modern agriculture.

The present invention relates to a method for post-emergent weed control, which comprises applying an effective amount of a composition comprising herbicide A (component A), trifludimoxazin (component B) and optionally saflufenacil (component C) to emerged weeds, or an area, where weeds are growing.

The invention discloses an active polypeptide of protoporphyrinogen oxidase and application, the active polypeptide not only has the activity of the protoporphyrinogen oxidase, but also has better tolerance to PPO inhibitor herbicides by transferring a nucleotide sequence for coding the active polypeptide. The herbicide tolerance is wide. The active polypeptide disclosed by the invention shows relatively high tolerance to PPO inhibitor herbicides, so that the active polypeptide has a wide application prospect in plants. The herbicide tolerance is high. The active polypeptide disclosed by the invention has strong tolerance to a PPO inhibitor herbicide, and shows high tolerance to saflufenacil, sulfentrazone, flumioxazin and lactofen which are 4 times of field concentration. The weed control method provided by the invention can effectively reduce the occurrence of resistant weeds, has broad-spectrum herbicide resistance, effectively reduces the cost, improves the control efficiency, and also can greatly avoid the occurrence of weed resistance.

The invention provides a synthesis method of saflufenacil, and belongs to the field of chemical synthesis. The preparation method comprises the following steps: reacting N-(2-chloro-4-fluoro-5-aminobenzoyl)-N '-isopropyl-N'-methyl sulfonamide serving as a raw material with chloroformate in a strong polar solvent, then directly adding alkali and ethyl 3-amino-4, 4, 4-trifluoro-2-butenoate into the reaction material, and carrying out cyclization reaction, so as to obtain the N-(2-chloro-4-fluoro-5-aminobenzoyl)-N '-isopropyl-N'-methyl sulfonamide. And carrying out methylation reaction on the cyclization reaction material and a methylation reagent to obtain saflufenacil. The selected reaction solvent is relatively single and easy to recover, so that the reaction operation is simple, the product yield is improved, and the method is suitable for industrial large-scale production and has a wide application prospect.

The present invention relates to herbicidal mixtures and their methods and uses for controlling undesirable vegetation in soybeans, wherein the herbicidal mixtures comprise L-glufosinate and and at least one herbicidal compound II selected from clethodim, cycloxydim, fenoxaprop, fenoxaprop-ethyl, fenoxaprop-P, fenoxaprop-P-ethyl, fluazifop, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, haloxyfop, haloxyfop-methyl, haloxyfop-P, haloxyfop-P-methyl, propaquizafop, quizalofop, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefuryl, sethoxydim, chlorimuron, chlorimuron-ethyl, nicosulfuron, oxasulfuron, thifensulfuron, thifensulfuron-methyl, tritosulfuron, imazamox, imazamox ammonium, imazapic, imazapic ammonium, imazapyr, imazapyr isopropylammonium, imazaquin, imazethapyr, imazethapyr ammonium, cloransulam, cloransulam-methyl, diclosulam, flumetsulam, atrazine, metribuzin, linuron, monolinuron, bentazone, bentazone-sodium, acifluorfen, acifluorfen-sodium, carfentrazone, carfentrazone-ethyl, flumiclorac, flumiclorac-pentyl, flumioxazin, fluthiacet, fluthiacet-methyl, fomesafen, lactofen, oxyfluorfen, saflufenacil, sulfentrazone, tiafenacil, trifludimoxazin, norflurazon, picolinafen, bicyclopyrone, clomazone, isoxaflutole, mesotrione, pyrasulfotole, tembotrione, topramezone, fenquinotrione, glyphosate, glyphosate-isopropylammonium, glyphosate-potassium, glyphosate-trimesium (sulfosate), pendimethalin, trifluralin; acetochlor, alachlor, butachlor, dimethenamid, dimethenamid-P, metazachlor, metolachlor, S-metolachlor, pethoxamid, pyroxasulfone, 2,4-D and its salts and esters, clopyralid and its salts and esters, dicamba and its salts and esters, quinclorac, quinclorac dimethylammonium, quinmerac, diflufenzopyr, diflufenzopyr-sodium, tepraloxydim, cinmethylin and other compounds.

The present application relates to the field of pesticide chemical industry technology, and discloses a post-treatment method for a saflufenacil-containing reaction solution. The post-treatment method includes the following steps: (1) after phase separation of a saflufenacil-containing reaction solution, performing desolvation treatment on an organic phase, and then adding a first organic solvent for stirring; (2) after the stirring is completed, performing filtration, leaching an obtained filter cake with a second organic solvent, and obtaining saflufenacil after drying. The post-treatment method provided by the present application can simply and efficiently treat the saflufenacil-containing reaction solution, with a product yield of over 90% and a content of about 98%.

The invention provides a triflumezopyrim-containing pesticide composition for preventing and treating sogatella furcifera, a pesticide preparation as well as a preparation method and application thereof, and belongs to the technical field of pest prevention and treatment. The nitenpyram and the pymetrozine are compounded with the trifluoro-benzene pyrimidine respectively, a synergistic effect is shown in a certain mass ratio range, the prevention and treatment effect on the sogatella furcifera can be improved (fast-acting property and persistent effect are achieved), the application dosage of chemical agents is reduced on the basis, and the prevention and treatment cost is reduced. The problems of pesticide residues, environmental pollution and the like caused by large-dose application are avoided to a certain extent.

The present invention relates to a method for post-emergent weed control, which comprises applying an effective amount of a composition comprising herbicide A (component A), trifludimoxazin (component B) and optionally saflufenacil (component C) to emerged weeds, or an area, where weeds are growing.

The present invention relates to high loaded suspension concentrate (SC) composition comprising a pesticide, a block copolymer, composed of a hydrophobic block and a hydrophilic block which contains negatively charged moieties (Poly Agro) and at least one non-ionic surfactant. Also, the present invention describes, a high loaded suspension concentrate (SC) composition, wherein: pyroxasulfone or saflufenacil is about 62 w / w % or is about 53 w / w %, respectively, with respect to the total weight on the composition: Poly Agro is from about 1 to about 10 w / w % with respect to the total weight on the composition; and at least one non-ionic surfactant is from about 1 to about 15 w / w % with respect to the total weight of the composition.

The present invention belongs to the field of pesticide insecticide technology and discloses an insecticidal composition containing trifluanid and its application. The active ingredients in the insecticidal composition include active ingredient A and active ingredient B, wherein active ingredient A is trifluanid and active ingredient B is either bifenthrin or isoxathiapiprolin. The mass ratio of active ingredient A to active ingredient B is 1:50 to 30:1. The insecticidal composition has excellent control effects on various crop pests. Due to the emergence of pests resistant to existing drugs, this application develops a new type of agricultural and horticultural insecticide.

The present invention relates to a combination or a composition comprising saflufenacil and epyrifenacil as well as to a method for weed control, which method comprises applying an effective amount of said herbicidal combination or composition to a non-crop area or to the cultivation area of a crop, where weeds grow or may grow. The invention also relates the use of the combination or of the composition comprising saflufenacil and epyrifenacil for weed control in a non-crop area or in the cultivation area of a crop.

The invention provides a sealed herbicide composition, which comprises 5-40% of active components, 0-20% of a dispersant, 0-20% of an emulsifier, 1-2% of a stabilizer, 0-2% of a viscosity modifier, 0-20% of a carrier and the balance of a dispersion medium, the active components comprise saflufenacil and pyroxasulfone, and the mass ratio of the saflufenacil to the pyroxasulfone is 1: (1-20). The herbicide composition provided by the invention is a compound combination of herbicides with different action mechanisms and has no cross resistance, so that the herbicidal characteristics of the herbicides with various components are well complementary in advantages, and the generation and progress of resistance of weeds to a single agent can be effectively delayed.

The present invention relates to herbicidal mixtures and their methods and uses for controlling undesirable vegetation in conventional and tolerant, e.g. glufosinate-tolerant, cotton, wherein the herbicidal mixtures comprise L-glufosinate and and at least one herbicidal compound II selected from clethodim, fluazifop, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, haloxyfop, haloxyfop-methyl, haloxyfop-P, haloxyfop-P-methyl, metamifop, quizalofop, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefuryl, chlorimuron, chlorimuron-ethyl, thifensulfuron, thifensulfuron-methyl, trifloxysulfuron, tritosulfuron, imazamethabenz, imazamethabenz-methyl, imazamox, imazamox ammonium, imazapic, imazapic ammonium, imazapyr, imazapyr isopropylammonium, imazaquin, imazethapyr, imazethapyr ammonium, pyrithiobac, pyrithiobac-sodium, amicarbazone, atrazine, prometryn, diuron, fluometuron, thiadiazuron, carfentrazone, carfentrazone-ethyl, flumiclorac, flumiclorac-pentyl, flumioxazin, fluthiacet, fluthiacet-methyl, fomesafen, pyraflufen, pyraflufen-ethyl, oxyfluorfen, saflufenacil, sulfentrazone, tiafenacil, trifludimoxazin, norflurazon, picolinafen, clomazone, topramezone, fenquinotrione, mesotrione, bicyclopyrone, isoxaflutole, tembotrione, tolpyralate, glyphosate, glyphosate dimethylammonium, glyphosate-isopropylammonium, glyphosate-potassium, glyphosate-trimesium (sulfosate), pendimethalin, trifluralin, acetochlor, alachlor, butachlor, dimethenamid, dimethenamid-P, metazachlor, metolachlor, S-metolachlor, pyroxasulfone, 2,4-D and its salts and esters, dicamba and its salts and esters, fluroxypyr, fluroxypyr-butometyl, fluroxypyr-meptyl, quinclorac, quinclorac dimethylammonium, quinmerac, cinmethylin, endothal, cycloxydim, sethoxydim, diflufenzopyr, diflufenzopyr-sodium, bentazone and bentazone-sodium and other compounds.

The invention provides an insecticidal composition containing an active component A and an active component B. The active component A is trifluorobenzene pyrimidine, the active component B is a compound shown as a formula I (formula I), the mass ratio of the active component A to the active component B is (1-20): (1-20), the insecticidal composition further comprises an auxiliary agent, the active component accounts for 1%-50% of the weight of the insecticidal composition, and the auxiliary agent accounts for 1%-50% of the weight of the insecticidal composition. The insecticidal composition is used for preventing and treating agricultural pests, has an obvious synergistic effect, and can reduce the dosage and delay the occurrence of pest resistance to drugs.

The present invention relates to herbicidal mixtures and their methods and uses for controlling undesirable vegetation in conventional and tolerant, e.g. glufosinate-tolerant, cotton, wherein the herbicidal mixtures comprise L-glufosinate and and at least one herbicidal compound II selected from clethodim, fluazifop, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, haloxyfop, haloxyfop-methyl, haloxyfop-P, haloxyfop-P-methyl, metamifop, quizalofop, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefuryl, chlorimuron, chlorimuron-ethyl, thifensulfuron, thifensulfuron-methyl, trifloxysulfuron, tritosulfuron, imazamethabenz, imazamethabenz-methyl, imazamox, imazamox ammonium, imazapic, imazapic ammonium, imazapyr, imazapyr isopropylammonium, imazaquin, imazethapyr, imazethapyr ammonium, pyrithiobac, pyrithiobac-sodium, amicarbazone, atrazine, prometryn, diuron, fluometuron, thiadiazuron, carfentrazone, carfentrazone-ethyl, flumiclorac, flumiclorac-pentyl, flumioxazin, fluthiacet, fluthiacet-methyl, fomesafen, pyraflufen, pyraflufen-ethyl, oxyfluorfen, saflufenacil, sulfentrazone, tiafenacil, trifludimoxazin, norflurazon, picolinafen, clomazone, topramezone, fenquinotrione, mesotrione, bicyclopyrone, isoxaflutole, tembotrione, tolpyralate, glyphosate, glyphosate dimethylammonium, glyphosate-isopropylammonium, glyphosate-potassium, glyphosate-trimesium (sulfosate), pendimethalin, trifluralin, acetochlor, alachlor, butachlor, dimethenamid, dimethenamid-P, metazachlor, metolachlor, S-metolachlor, pyroxasulfone, 2,4-D and its salts and esters, dicamba and its salts and esters, fluroxypyr, fluroxypyr-butometyl, fluroxypyr-meptyl, quinclorac, quinclorac dimethylammonium, quinmerac, cinmethylin, endothal, cycloxydim, sethoxydim, diflufenzopyr, diflufenzopyr-sodium, bentazone and bentazone-sodium and other compounds.

The invention discloses a weeding composition, the effective components of the weeding composition comprise an active component A, an active component B and an active component C. The active component A is saflufenacil, the active component B is topramezone, and the active component C is atrazine or terbuthylazine. The weeding composition can be used for preventing and removing various annual or perennial weeds in corn fields, broad-spectrum weeding can be achieved, the preventing and removing effect is improved, the drug resistance of the weeds is delayed, meanwhile, the use amount of a single herbicide is reduced, and the environmental influence is reduced.

The present invention provides suspoemulsion formulations comprising: (i) a continuous aqueous phase comprising saflufenacil which is suspended in said continuous aqueous phase; (ii) a liquid organic phase comprising fluroxypyr or a salt, an ester, or a combination thereof, and a water-immiscible solvent; and (iii) a surfactant. Such formulations are useful in controlling weed.

The invention provides missible oil containing saflufenacil and clethodim and a preparation method of the missible oil, and the missible oil comprises the following components in percentage by mass: 5%-60% of the clethodim, 1%-20% of the saflufenacil, 10%-20% of an emulsifier, 5%-20% of a synergist, 10%-35% of a cosolvent and the balance of a solvent. By adjusting the combination of the solvent and the auxiliary agent, the stability problem of saflufenacil crystals and clethodim separated out by diluting missible oil with water is solved while the saflufenacil is ensured to be dissolved, the combination has no influence on the stability of the clethodim basically, the decomposition rate of the clethodim is stably controlled within 8.5%, and the stability of the clethodim is greatly improved. It can be guaranteed that no raw pesticide is separated out of pesticide liquid under the use concentration of missible oil, the risk that a spray head is blocked is avoided, and the pesticide effect of saflufenacil can be achieved easily. The composition improves the stability of the effective components, enhances the formula effect, and can ensure excellent pesticide effect. The improvement of the clethodim stability also prolongs the shelf life of the preparation.

The present invention relates to herbicidal mixtures and their methods and uses for controlling undesirable vegetation in conventional and tolerant, e.g. glufosinate-tolerant, cotton, wherein the herbicidal mixtures comprise L-glufosinate and and at least one herbicidal compound II selected from clethodim, fluazifop, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, haloxyfop, haloxyfop-methyl, haloxyfop-P, haloxyfop-P-methyl, metamifop, quizalofop, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefuryl, chlorimuron, chlorimuron-ethyl, thifensulfuron, thifensulfuron-methyl, trifloxysulfuron, tritosulfuron, imazamethabenz, imazamethabenz-methyl, imazamox, imazamox ammonium, imazapic, imazapic ammonium, imazapyr, imazapyr isopropylammonium, imazaquin, imazethapyr, imazethapyr ammonium, pyrithiobac, pyrithiobac-sodium, amicarbazone, atrazine, prometryn, diuron, fluometuron, thiadiazuron, carfentrazone, carfentrazone-ethyl, flumiclorac, flumiclorac-pentyl, flumioxazin, fluthiacet, fluthiacet-methyl, fomesafen, pyraflufen, pyraflufen-ethyl, oxyfluorfen, saflufenacil, sulfentrazone, tiafenacil, trifludimoxazin, norflurazon, picolinafen, clomazone, topramezone, fenquinotrione, mesotrione, bicyclopyrone, isoxaflutole, tembotrione, tolpyralate, glyphosate, glyphosate dimethylammonium, glyphosate-isopropylammonium, glyphosate-potassium, glyphosate-trimesium (sulfosate), pendimethalin, trifluralin, acetochlor, alachlor, butachlor, dimethenamid, dimethenamid-P, metazachlor, metolachlor, S-metolachlor, pyroxasulfone, 2,4-D and its salts and esters, dicamba and its salts and esters, fluroxypyr, fluroxypyr-butometyl, fluroxypyr-meptyl, quinclorac, quinclorac dimethylammonium, quinmerac, cinmethylin, endothal, cycloxydim, sethoxydim, diflufenzopyr, diflufenzopyr-sodium, bentazone and bentazone-sodium and other compounds.

The present invention relates to herbicidal mixtures and their methods and uses for controlling undesirable vegetation in soybeans, wherein the herbicidal mixtures comprise L-glufosinate and and at least one herbicidal compound II selected from clethodim, cycloxydim, fenoxaprop, fenoxaprop-ethyl, fenoxaprop-P, fenoxaprop-P-ethyl, fluazifop, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, haloxyfop, haloxyfop-methyl, haloxyfop-P, haloxyfop-P-methyl, propaquizafop, quizalofop, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefuryl, sethoxydim, chlorimuron, chlorimuron-ethyl, nicosulfuron, oxasulfuron, thifensulfuron, thifensulfuron-methyl, tritosulfuron, imazamox, imazamox ammonium, imazapie, imazapie ammonium, imazapyr, imazapyr isopropylammonium, imazaquin, imazethapyr, imazethapyr ammonium, cloransulam, cloransulam-methyl, diclosulam, flumetsulam, atrazine, metribuzin, linuron, monolinuron, bentazone, bentazone-sodium, acifluorfen, acifluorfen-sodium, carfentrazone, carfentrazone-ethyl, flumiclorac, flumiclorac-pentyl, flumioxazin, fluthiacet, fluthiacet-methyl, fomesafen, lactofen, oxyfluorfen, saflufenacil, sulfentrazone, tiafenacil, trifludimoxazin, norflu-razon, picolinafen, bicyclopyrone, clomazone, isoxaflutole, mesotrione, pyrasulfotole, tembotri-one, topramezone, fenquinotrione, glyphosate, glyphosate-isopropylammonium, glyphosate-potassium, glyphosate-trimesium (sulfosate), pendimethalin, trifluralin; acetochlor, alachlor, bu-tachlor, dimethenamid, dimethenamid-P, metazachlor, metolachlor, S-metolachlor, pethoxamid, pyroxasulfone, 2,4-D and its salts and esters, clopyralid and its salts and esters, dicamba and its salts and esters, quinelorac, quinclorac dimethylammonium, quinmerac, diflufenzopyr, diflufenzopyr-sodium, tepraloxydim, cinmethylin and other compounds.

The present disclosure relates to a herbicidal combination comprising a carbamate herbicide and at least one additional protoporphyrinogen oxidase (PPO) inhibitor herbicide. In particular, the disclosure relates to combinations of the carbamate asulam with at least one PPO inhibitor selected from carfentrazone, saflufenacil, tiafenacil, fomesafen, flumioxazin or epyrifenacil.

The invention relates to the technical field of fine chemical engineering, in particular to a continuous production method of a saflufenacil intermediate, which at least comprises the following steps: S1, respectively controlling the flow rate of a nitration reagent and 2-chloro-4-fluoro-trichloromethyl benzene by using a metering pump, and carrying out two-stage reaction on the nitration reagent and the 2-chloro-4-fluoro-trichloromethyl benzene through a two-stage reactor in sequence, the 2-chloro-4-fluoro-5-nitryl-trichloromethyl benzene crude product is obtained; s2, adding a solvent into the 2-chloro-4-fluoro-5-nitro-trichloromethyl benzene crude product, then dropwise adding into water for quenching, then carrying out phase separation, washing a lower oil phase with water, neutralizing and recovering the solvent to obtain a 2-chloro-4-fluoro-5-nitro-trichloromethyl benzene product, concentrating the water phase to obtain a byproduct, and recycling the byproduct to obtain the 2-chloro-4-fluoro-5-nitro-trichloromethyl benzene. The method effectively solves the problems of poor safety and incapability of avoiding nitration isomers in the prior art, and is very suitable for industrial large-scale production.

The present invention relates to use of protoporphyrinogen oxidase. A method for controlling weeds comprises applying a herbicide containing an effective dose of PPO inhibitor to a field with at least one transgenic plant. The transgenic plant has a polynucleotide sequence encoding protoporphyrinogen oxidase in a genome thereof, and has reduced plant damage and / or increased plant production compared to other plants that do not have a polynucleotide sequence encoding protoporphyrinogen oxidase. According to the present invention, the protoporphyrinogen oxidase PPOA-PPOF has a relatively high tolerance to a PPO inhibitor herbicide, and the plants having the polynucleotide sequence encoding protoporphyrinogen oxidase have great tolerance to the PPO inhibitor herbicide, and show high-resistance tolerance to almost all 4-fold field concentrations of saflufenacil, oxyfluorfen, and flumioxazin. Therefore, the application prospect for plants is wide.

The present invention relates to a novel nitration process of 2-chloro-4-fluorobenzoic acid or alkyl 2-chloro-4-fluorobenzoate, using oleum and nitric acid, to obtain 2-chloro-4-fluoro-5-nitrobenzoic acid or alkyl 2-chloro-4-fluoro-5-nitrobenzoates; purifying the crude reaction product; and recovering 2-chloro-4-fluoro-5-nitrobenzoic acid or alkyl 2-chloro-4-fluoro-5-nitrobenzoates in an essentially pure form, which can be used in the synthesis of the herbicide saflufenacil.

The invention belongs to the field of pesticide intermediates and product preparation, and particularly relates to a method for continuously preparing trifluorobenzene pyrimidine. According to the method disclosed by the invention, pyrimidine-5-formaldehyde and 2-aminopyridine are used as starting substrates, and are subjected to Schiff base reaction, reductive amination reaction and cyclization reaction in sequence, and the target product trifluorobenzene pyrimidine is obtained after post-treatment. According to the invention, a multi-step continuous flow process for preparing trifluorobenzene pyrimidine through Schiff base reaction-reductive amination reaction-cyclization reaction based on a flow chemistry technology is found for the first time, the total retention time of the reaction is less than 30 minutes, the total conversion rate reaches 58%, and the total yield reaches 39%. Compared with the prior art, the method has the advantages that the reaction time is greatly shortened, meanwhile, through solvent compatibility and post-treatment simplification, the yield of three wastes in the reaction process is effectively reduced, the post-treatment operation frequency and reaction reagent consumption are greatly reduced, and efficient and green production is realized.

The invention discloses a weeding composition containing saflufenacil and tembotrione, the effective components of the weeding composition comprise an active component A, an active component B and an active component C. The active component A is saflufenacil, the active component B is tembotrione, and the active component C is terbuthylazine. The weeding composition can be used for preventing and removing annual or perennial weeds, is wide in weeding spectrum, can remarkably improve the utilization rate of the herbicide, reduces the dosage, prolongs the service life of the herbicide, and makes a contribution to agricultural sustainable development.