71results about How to "Avoid inhibition" patented technology

The invention discloses a medicine image detection method based on an improved Canny operator, and the method comprises the steps: 1) collecting a medicine image, and carrying out the graying processing of the medicine image; 2) an improved bilateral filter is adopted to filter the medicine image after graying processing, and noise is suppressed; 3) carrying out gradient amplitude and phase extraction on the medicine image by adopting a four-direction Soble operator; 4) performing non-maximum suppression on the extracted gradient amplitude and phase by adopting improved non-maximum suppression, and accurately positioning a target edge; 5) performing adaptive threshold extraction by using Otsu improved based on gradient edge information to obtain a drug image edge contour; and 6) outputting the edge contour of the medicine image. By adjusting the weight value of the edge pixel point identified by the bilateral filter to be zero, the interference to the central pixel point is effectively reduced, so that the target edge and detail features of the image are reserved to the greatest extent.

The invention discloses a special growth-promoting microbial fertilizer for saline-alkali soil and a preparation method of the special growth-promoting microbial fertilizer, and belongs to the technical field of growth-promoting microbial fertilizer.The special growth-promoting microbial fertilizer for saline-alkali soil is obtained by mixing organic manure, ammonium humate, fungicide particles, crop straw, slow-release phosphate fertilizer particles, hydroxyapatite, chitosan and citric acid in proportion; according to the granular microbial inoculum carrier, the biochar particles and the iron-carbon composite microspheres serve as matrixes, the raw materials such as the fly ash form a foaming porous adhesive substance under the action of alkali excitation, the matrixes such as the biochar particles are bonded, a stable porous structure can be formed easily, a proper environment is provided for growth of phosphate solubilizing bacteria, and the phosphate solubilizing and growth promoting effects of the phosphate solubilizing bacteria are improved. The microbial agent particles have good water absorption and can adsorb sodium ions in soil after being watered, and calcium and magnesium components contained in the fly ash-based adhesive substance can be exchanged with the sodium ions to play a fixing role, so that the salt stress effect on crops is reduced.

The embodiment of the invention relates to the field of image recognition, and discloses a super-capacitor electrode surface area detection method and system and electronic equipment, and the method comprises the steps: carrying out the multi-layer discrete wavelet decomposition of a collected image, and carrying out the nonlinear enhancement of a high-frequency coefficient of each layer according to different decomposition layers; performing reconstruction and noise reduction on the enhanced image by using a soft threshold method, wherein a threshold parameter is determined according to a decomposition level and a noise standard deviation; constructing a plurality of circular structure elements with different scales, extracting different aperture features correspondingly, and calculating a morphological gradient of each scale by adopting a Gaussian kernel; statistical features are calculated through a local window, a threshold value is determined, weighted fusion is conducted on the features of multiple scales, and the weight coefficient is decreased progressively along with increasing of the aperture. Through the scheme of the invention, the identifiability of micropore and mesoporous structures in the image can be improved, and accurate nondestructive detection of the surface area of the electrode is realized.

The invention discloses a new energy transmission line inter-phase fault distance measurement method and system, and the method comprises the steps: starting an element to act after a fault occurs, and inputting low-voltage ride-through control and complex-frequency signal injection control; fault phase selection is realized according to a voltage phase selection element, and fault phase voltages and currents under two characteristic frequencies are extracted through filtering; if the fault is a two-phase short-circuit fault, extracting and replacing the fault phase-to-phase voltage, and replacing the transition resistor with Rf / 2; if the fault is a three-phase short-circuit fault, the phasors of the phase voltage and current difference of any two phases are brought in; according to the equivalent circuit under the characteristic frequency, a frequency domain parameter equation about the fault distance is obtained; respectively splitting a real part and an imaginary part of the frequency domain parameter equation of the fault distance to obtain a real coefficient equation set about the fault distance; when the non-power-frequency electrical quantity is extracted, the real coefficient equation set is expanded into an overdetermined equation with the equation number of 4N, and the solution of the overdetermined equation in the least square meaning is solved; and obtaining a distance measurement result of the new energy transmission line.

The invention relates to a method for enriching anaerobic ammonium oxidation bacteria under combined regulation and control of NLR and HRT in the technical field of biological sewage treatment, and aims to solve the problems that the anaerobic ammonium oxidation bacteria are greatly influenced by the environment and are slowly enriched, NH4 < + >-N and NO2 <->-N with low matrix concentration are pumped into an SBR (Sequencing Batch Reactor); and the enrichment of anaerobic ammonium oxidation bacteria is successfully realized by continuously changing hydraulic retention time and water inlet matrix concentration. The total nitrogen removal rate is stabilized at 75%, the removal efficiency is good, the reactor can be flexibly regulated and controlled, rapid starting of the anaerobic ammonia oxidation reactor is facilitated, and a theoretical reference is provided for practical application of the Anammox process. The system is simple to operate, convenient to operate and manage and high in treatment efficiency, and has a good popularization and application prospect.

The invention discloses a biological control preparation, system and application thereof for preventing and controlling tomato leafminer, wherein the biological control preparation comprises Beauveria bassiana and a food attractant, wherein the food attractant comprises an attractant substance and a solvent, wherein the attractant substance comprises tetradecatrienol acetate, ethyl octanoate, 1-nonanol, phenylacetaldehyde and 3-methyl-1-butanol. By using the food attractant in combination with Beauveria bassiana, the amount of attraction to tomato leafminer is increased, and at the same time, the germination of conidia of Beauveria bassiana is not affected, thereby improving the transmission efficiency of tomato leafminer to Beauveria bassiana, and achieving a sustained biological control effect.

This application discloses a method and apparatus for constructing a multi-scale adaptive gating MambaPlus network, belonging to the field of artificial intelligence and machine learning technology. The method includes: initializing the network configuration and constructing the basic structure; preprocessing the input data to generate a standard dataset; mapping the input data to the hidden space via an input mapping layer, and extracting backbone features from the Mamba backbone; constructing at least two parallel scale branches in the hidden space to obtain a multi-scale feature set; inputting the backbone features and multi-scale features into an adaptive gating module, dynamically allocating weights and adaptively fusing them through a hierarchical gating mechanism to generate fused features; further enhancing the features through cross-scale attention and feedforward enhancement, and then superimposing the residuals to generate the final discriminative features; finally, completing category prediction and model training evaluation. This application, while retaining the advantages of Mamba's long-range dependency modeling, addresses the problems of insufficient utilization of multi-scale information, poor adaptive feature fusion, and low robustness in complex scenarios.

The invention provides a method for rapidly recovering denitrification efficiency of an anaerobic ammonium oxidation system, and aims to solve the problem of insufficient activity of anaerobic ammonium oxidation bacteria in a limited reactor. The lateral flow high-activity anaerobic ammonium oxidation bacteria are introduced, 5-6 mg / L of Fe < 3 + > is added into the inlet water, and meanwhile, the hydraulic retention time is adjusted, so that the adaptability and denitrification rate of the anaerobic ammonium oxidation bacteria are remarkably improved. Experiments show that the method increases the denitrification rate from 40mg N / L / d to 160mg N / L / d, and the amplification reaches 300%. Besides, hollow plastic small balls with the diameter of 16mm are laid in the reactor, so that a strict anaerobic environment is ensured, and the activity recovery of anaerobic ammonium oxidation bacteria is facilitated. The Fe < 3 + > optimizes the growth environment of microorganisms, enhances the flora stability and the denitrification efficiency, inhibits the competition of harmful microorganisms, and is simple to operate and environment-friendly. The overall efficiency of the sewage treatment system is greatly improved, the energy consumption and the sludge yield are reduced, the denitrification cost is reduced, and the system is suitable for various sewage treatment scenes with efficient denitrification requirements.

The invention relates to the technical field of video monitoring, in particular to a multi-azimuth identification video monitoring system, which comprises a data acquisition module, a data analysis module and a result analysis module, and is characterized in that a picture of a monitoring area is acquired through the data acquisition module, then a target detection model in the data analysis module is used for detecting the picture, and a result is obtained through the result analysis module; determining a detection frame of a target position and a detection result thereof, wherein the detection result comprises a position, a size, a category and confidence; the result analysis module ranks all the detection frames from high to low according to confidence coefficients, selects the detection frame with the highest confidence coefficient as the current optimal detection frame, and calculates a dynamic overlap suppression threshold value according to the position, size and category of the current optimal detection frame; and then, calculating the intersection-to-union ratio of the other detection frames and the current optimal detection frame, gradually adjusting the confidence coefficients of the other detection frames according to the overlap suppression threshold value and the intersection-to-union ratio, and repeating the steps after reordering until all the detection frames are processed.

The invention discloses an efficient preparation method of trioctyl phosphate, which specifically comprises the following steps: mixing a catalyst and isooctyl alcohol, dropwise adding phosphorus oxychloride under a low-temperature condition (5-15 DEG C), keeping the temperature at 15 DEG C for 0.5 hour after dropwise adding, starting vacuum, and keeping the temperature for 2-3 hours to remove a large amount of HCl generated by reaction; under the conditions that the temperature is 60-80 DEG C and the vacuum degree is 0.098 MPa or above, reaction liquid obtained after heat preservation is completed enters a film evaporator through a peristaltic pump, diester acyl chloride which does not completely react in the reaction liquid is rapidly reacted through a film scraper to generate trioctyl phosphate, meanwhile, generated HCl is rapidly taken out, integrated synthesis is achieved, side reactions are reduced, and crude trioctyl phosphate is obtained; and carrying out dealcoholization, neutralization, light component removal and molecular distillation on the crude product to obtain a trioctyl phosphate finished product. The method is simple in process, and in a crude product obtained after esterification synthesis, the byproduct dioctyl phosphate is less, the purity is high, and the reaction is rapid; and mass production can be carried out by using existing equipment.

The invention discloses a domestication method and device for salt-tolerant activated sludge, and belongs to the technical field of microculture and sewage treatment devices. In order to solve the technical problems that in the prior art, domestication of salt-tolerant activated sludge is achieved in the mode that salinity is increased in a gradient mode, obtained sludge is poor in genetic adaptability and long in domestication period, the domestication method of the salt-tolerant activated sludge comprises the steps that fresh sludge with the sludge concentration MLSS being 5000-6000 mg / L and the MLSS / MLVSS being larger than or equal to 0.8 is put into a domestication device; the domestication device comprises an anaerobic-anoxic reaction zone and an aerobic reaction zone which are communicated with each other; the concentration of salt in the system is controlled to be 3-5%, when the CODcr removal rate is smaller than or equal to 30%, the CODcr concentration gradient is gradually increased at the gradient of 500-1000 mg / L in the modes of increasing nutrition addition, increasing the aeration rate of the aerobic reaction zone, returning the sludge in the aerobic reaction zone to the anaerobic-anoxic reaction zone, supplementing fresh sludge, discharging inactivated sludge and the like, and the obtained salt-tolerant activated sludge is good in heredity and high in salt tolerance. And the domestication period is short.

The invention relates to the technical field of immune carriers, in particular to immune carrier microspheres loaded with individualized MHC-II binding polypeptide and vaccine preparation and application of the immune carrier microspheres loaded with the individualized MHC-II binding polypeptide. The core microsphere is loaded with individualized MHC-II binding polypeptide, the sequence of the MHC-II binding polypeptide is obtained by predicting and screening based on an HLA genotyping result, and each HLA allele corresponds to at least one high-affinity MHC-II binding polypeptide; and the shell is a glucan or other polymer coating layer. The preparation method has the advantages that the T epitope and the B epitope are separately subjected to immune competitive inhibition inside and outside the microspheres, so that a better immune effect is obtained. The antibody avoids cross reaction side effects; carrier molecule diversity is reduced, and side effects caused by T cell over-activation are avoided; th1 epitopes and Th2 epitopes can be contained in the microspheres, so that antibody immunity and T cell immunity functions are generated; the particle size of the microspheres is controllable, and the immunologic function can be achieved without adjuvants.

The invention discloses a sewage plant tail water treatment system and method, and relates to the technical field of sewage treatment.The sewage plant tail water treatment system is applied to tail water generated by a sewage plant adopting an ozone advanced oxidation technology, and the treatment system comprises an activated carbon reaction device, a denitrification reaction device, an ecological pond and a horizontal subsurface flow wetland; the activated carbon reaction device is communicated with the tail water pipe and comprises an activated carbon filtering layer, and the activated carbon filtering layer is used for adsorbing chemical oxygen demand and dissolved oxygen in tail water; the denitrification reaction device is communicated with the activated carbon reaction device and comprises a denitrification filter material layer, and the denitrification filter material layer is used for autotrophic denitrification nitrogen removal of tail water; the ecological pond is communicated with the denitrification reaction device and comprises aquatic plants and aquatic animals; the horizontal subsurface flow wetland is communicated with the ecological pond and is used for deeply filtering the tail water. The treatment system can improve the purification effect of the tail water of the sewage plant.

The invention discloses a biochemical constant-temperature incubator with a sterilization function, and relates to the field of constant-temperature culture.The biochemical constant-temperature incubator comprises an incubator shell, supporting legs are symmetrically arranged at the bottom of the incubator shell, a sealing door is rotatably connected to the front face of the incubator shell, an air inlet mechanism is fixedly connected to the bottom of the outer surface of the incubator shell, and an air outlet mechanism is fixedly connected to the top of the outer surface of the incubator shell; a heat preservation layer is fixedly connected to the inner wall of the box shell, a heating mechanism is fixedly connected to the bottom of the heat preservation layer, an adjusting mechanism is fixedly connected to the top of the heating mechanism, cultured microorganisms are placed on the adjusting mechanism, and the adjusting mechanism can control and protect the cultured microorganisms; then the air inlet mechanism evolves and sucks outside air, the outside air is heated through the heating mechanism and flows out of the device from the air outlet mechanism, and then constant temperature in the incubator is achieved.

The invention relates to the technical field of primary explosive production equipment, and particularly discloses a continuous chemical combination reactor which comprises a reactor body, the side wall of the reactor body is hollow, a mechanical stirring device is fixedly arranged on the upper end face of the reactor body, and one end of the mechanical stirring device extends into the reactor body; a raw material solution pipe and a water inlet pipe are arranged on one side of the mechanical stirring device; a sensor is arranged on one side of the stirring device, and one end of the sensor extends into the reactor; the side wall of the reactor is provided with a cold and hot water inlet and a cold and hot water return port which are circularly communicated with the interlayer of the reaction kettle; a gas pipe is arranged at the bottom of the reactor and inserted into the bottom of the reactor; a discharge hole is formed in the lower end of the reactor, the discharge hole is communicated with a plurality of suction filtration tanks arranged at the lower end of the discharge hole, and a valve is arranged between the discharge hole and each suction filtration tank; the invention aims to enable the concentration of materials and reaction conditions in the reaction process to be always kept stable in a continuous feeding and discharging mode, the generated initiating explosive particles are uniform in size, the yield is high, the production is simple, and the cost is reduced.

The present invention provides a neuroactive steroid solid dispersion, a solid dispersion composition, a preparation method and application, and a drug containing the solid dispersion, and belongs to the field of pharmaceutical technology. The present invention melt-extrudes a raw material mixture to obtain a neuroactive steroid solid dispersion; the raw material mixture includes 10 to 70 parts of neuroactive steroids, 30 to 90 parts of carrier materials, and 0 to 60 parts of plasticizers by mass; the temperature of the melt extrusion is <160°C; the neuroactive steroid in the neuroactive steroid solid dispersion exists in an amorphous state, and the particle size of the neuroactive steroid in the neuroactive steroid solid dispersion is ≤200nm. The neuroactive steroid in the neuroactive steroid solid dispersion provided by the present invention has a high oral bioavailability.

This application discloses an electronic atomized product and a method for determining its nicotine content. The nicotine content in this electronic atomized product is no higher than 500 ng / g, simulating the action and visual experience of smoking, assisting users in adapting to the transition phase without nicotine dependence, and aiding in smoking cessation. The method for determining the nicotine content in the electronic atomized product includes: ultrasonic extraction of the sample using ultrapure water; liquid chromatography separation using an alkaline aqueous phase (pH 9.22–10.76) and acetonitrile as the mobile phase; positive ion ionization using an electrospray ionization source; and detection of nicotine characteristic ions using a single quadrupole mass spectrometer in selected ion monitoring mode, achieving highly sensitive, highly selective, low-cost, stable, and reliable quantitative analysis of nicotine content.

The utility model relates to experimental device technical field, concretely relates to a kind of paddy field soil remediation experimental device based on photosynthetic bacteria. Specific technical scheme is: including soil culture container, multiple partitions are horizontally and detachably arranged in the soil culture container, a plurality of small holes are arranged on the partition, filter screen is arranged on the partition and the inner bottom surface of soil culture container, a channel with one end opening is horizontally arranged in the partition, the top of the partition is provided with multiple through holes communicated with the channel, pipeline is inserted in the channel, the top surface of the pipeline is provided with multiple insertion holes, and corresponds with the through hole, diffusion tube is sequentially inserted into insertion hole and communicated by passing through filter screen and through hole, liquid inlet pipe is arranged outside soil culture container, liquid inlet pipe is communicated with pipeline, and liquid inlet pipe is communicated with bacteria liquid tank.The utility model can simulate paddy field ecological environment, provide suitable growth and metabolism conditions for photosynthetic bacteria, so as to systematically study the repair effect of photosynthetic bacteria on paddy field soil.

The invention discloses a beneficiation method for improving the nickel recovery rate of high-content talc nickel sulfide ore. The beneficiation method comprises the following steps that A, raw materials are pretreated; b.1, a roughing process: feeding the ore pulp A3 obtained in the step A.3.1 into a roughing flotation machine to carry out roughing operation for four times; b.2, the roughing concentrate B1 obtained in the step B.1 is fed into a stirring tank, and 280 g / t of CMC, 550 g / t of water glass and 50 g / t of butyl xanthate are added; c.1, primary fine selection; c.2, carrying out secondary fine selection; c.3, third-time concentration: feeding the secondary concentrate product C3 into a flotation machine for third-time concentration, adding water to adjust the concentration of ore pulp to 12-15%, filling 3122 Am < 3 > / h into the ore pulp, and carrying out flotation for 10-12 minutes to obtain a third-time concentrate product C5 and third-time concentration tailing products C6 and C5 which serve as final concentrates to be concentrated and filtered for sale; and the third-time concentration tailing product C6 is fed into the step C.2.

This disclosure relates to a voice call processing method, circuit, apparatus, medium, chip, and terminal, belonging to the field of electronic technology, and can improve the sensitivity of signals used for proximity detection. A voice call processing method includes: during a voice call at the terminal, receiving a sampled signal acquired by the terminal's microphone, wherein the sampled signal includes a first voice signal and a proximity detection signal for proximity detection; filtering the sampled signal to remove the first voice signal and obtain the proximity detection signal; amplifying the filtered proximity detection signal; performing analog-to-digital conversion on the amplified proximity detection signal; and determining a proximity detection result based on the analog-to-digital converted proximity detection signal.

The invention relates to a carbamate pesticide residue rapid detection non-woven fabric and a preparation method thereof, the carbamate pesticide residue rapid detection non-woven fabric comprises an outer package, the outer package is internally provided with an enzyme-containing cloth, a water-soluble film, an indigo-containing cloth, a color-developing cloth, a flash-evaporation non-woven fabric and a warm paste, and the enzyme-containing cloth, the water-soluble film, the indigo-containing cloth, the color-developing cloth, the flash-evaporation non-woven fabric and the warm paste are stacked and connected from top to bottom. The preparation method comprises the following steps: dipping pure cotton spunlaced non-woven fabric in a cholinesterase gelatin solution, taking out and airing to obtain enzyme-containing fabric, dipping the pure cotton spunlaced non-woven fabric in an indophenol acetate solution, taking out and airing to obtain indigo-containing fabric, and drying to obtain the indigo-containing fabric. The enzyme-containing cloth, the water-soluble film, the indigo-containing cloth, the color-developing cloth, the flash-evaporation-method non-woven cloth and the warm paste are mutually connected and put into an outer package, and finally the interior of the outer package is vacuumized to obtain the quick-test non-woven cloth. The method is simple and convenient to operate, high in detection speed and high in detection result accuracy.

The present invention discloses a carbon-based adsorption / microbial aerobic degradation risk control composite material and its application, which belongs to the field of groundwater remediation technology. The composite material has a core-shell structure, including an aerobic degradation bacteria shell and a functional material core. The functional material of the core is composed of adsorption-type biochar, oxygen slow-release agent calcium peroxide and recovery-promoting factor, which are fixed by sodium alginate and calcium chloride. The aerobic shell is composed of petroleum hydrocarbon aerobic degradation bacteria Rhodococcus pyridinus, which is naturally formed on the surface of microspheres through biofilm. The material is used for aerobic bacteria to construct a local aerobic habitat in the groundwater environment, Rpf is used to improve the degradation activity of aerobic bacteria, and oxygen slow-release agents are used to overcome the inhibitory effect of groundwater oxygen deficiency on the activity of aerobic bacteria. The composite material prepared by the present invention can be used to repair groundwater contaminated by petroleum hydrocarbons, and this material has the advantages of high efficiency, long-term effect, low cost, no secondary pollution, and simple preparation method, and has the potential for large-scale promotion and application.

The invention discloses application of quercetin in reduction of the number of resistance genes in soil, solid bacterial fertilizer and a preparation method, and relates to the technical field of preparation of solid bacterial fertilizer and reduction of the number of resistance genes. Quercetin is introduced in the fermentation process of the solid bacterial fertilizer to inhibit propagation and diffusion of resistance genes, and the ecological safety of the bacterial fertilizer is improved on the premise that growth and proliferation of beneficial microorganisms are not affected. The concentration (0.01%-0.05%) of quercetin and the adding mode (added in the first-stage fermentation) are precisely designed, and the inhibition effect of quercetin on beneficial bacteria can be effectively avoided, so that the high efficiency and safety of the bacterial fertilizer are guaranteed.

The invention relates to the technical field of pulping and papermaking, and provides a composite biological enzyme assisted low-energy-consumption pulping method. The method comprises the following steps: S100, pretreating raw materials, adding a compound bio-enzyme preparation and a softening agent, and carrying out softening treatment to obtain a mixture; s200, performing mechanical pulping on the mixture, and performing filament separation treatment through twisting and grinding equipment to form pulp; s300, bleaching treatment and cleaning treatment are conducted on the pulp, and the pulping process is completed; wherein the composite biological enzyme preparation comprises laccase, cellulase, xylanase, pectinase and magnetic particles. The composite bio-enzyme preparation can reduce energy consumption in the pulping process, is beneficial to reduction of production cost and improvement of production efficiency, replaces traditional chemical agents with the composite bio-enzyme preparation, reduces environmental pollution, effectively improves the decomposition rate of plant fibers, enables pulp to be easier to obtain, and improves the utilization rate of raw materials.

The invention discloses a centimeter-level continuous flow reaction device which comprises at least one liquid storage tank, a gas cylinder, a T-shaped mixer and a micro-reactor, inlets of the liquid storage tank and the gas cylinder are communicated with two ends of the T-shaped mixer respectively, the other end of the T-shaped mixer is connected with the micro-reactor, the micro-mixer is arranged between the T-shaped mixer and the micro-reactor, and the T-shaped mixer is connected with the micro-reactor. The micro-mixer is filled at an inlet of the micro-reactor, the micro-mixer is provided with a pore channel communicated with a channel of the micro-reactor, and a gas-liquid mixture generates bubbles after flowing through the micro-mixer. The invention further discloses an application of the device in a gas-liquid two-phase participated reaction in continuous flow, in particular an application of catalyzing cyclohexanol to prepare epsilon-caprolactone by using ADH1-BVMO whole-cell sap. The invention provides a universal, simple and convenient device and method for improving the oxygen transmission efficiency for the biological catalysis aerobic reaction, and provides actual examples and references for the biological catalysis aerobic reaction in continuous flow.

The present application relates to the technical field of pulping and papermaking, and provides a composite biological enzyme assisted low-energy consumption pulping method.The method comprises the following steps: S100, pretreating raw materials, adding a composite biological enzyme preparation and a softening agent, and performing softening treatment to obtain a mixture; S200, mechanically pulping the mixture, performing filament separation treatment through a rubbing equipment, and forming a pulp liquid; S300, performing bleaching treatment and cleaning treatment on the pulp liquid, and completing the pulping process; wherein the composite biological enzyme preparation comprises laccase, cellulase, xylanase, pectinase and magnetic particles.The composite biological enzyme preparation can reduce the energy consumption in the pulping process, helps to reduce the production cost, improves the production efficiency, replaces the traditional chemical agent with the composite biological enzyme preparation, reduces the environmental pollution, effectively improves the decomposition rate of plant fibers, makes the pulp more easily obtained, and improves the utilization rate of raw materials.

The invention relates to the technical field of gene engineering and enzyme catalysis, and discloses a method for synthesizing non-natural chiral alpha-amino acid through one-pot double-enzyme tandem catalysis. According to the method provided by the invention, decarboxylase (AnFdcUbix), ammonia lyase (LsPAL), ammonium carbamate and ammonium bicarbonate are added into a water phase, so that substrate olefin is subjected to carboxylation under the catalysis of the decarboxylase (AnFdcUbix), and alpha-amino acid with an ee value of 99% is obtained through the catalysis of the ammonia lyase (LsPAL). According to the one-pot method, the step of separating an intermediate product can be avoided, meanwhile, the generated intermediate is converted into the product alpha-amino acid, and the problem of product inhibition is avoided. The alpha-amino acid prepared by the method has high yield. In addition, the method can be applied to synthesis of L-phenylpropionic acid and derivatives thereof, and has great application value and market prospect.

The invention discloses a single-bacterium fermentation compounding method of cattle feed, and relates to the technical field of feed fermentation. Comprising the following steps: preparing a single-bacterium fermentation bacterial material, the single-bacterium fermentation bacterial material comprises 42.25-47.25 parts of wheat bran, 19-21 parts of soybean meal, 14.25-15.75 parts of corn flour, 19-21 parts of rice hull powder and 0.003-0.005 part of a bacterial liquid, and strains used by the bacterial liquid comprise six probiotics including saccharomyces cerevisiae, bacillus subtilis, bacillus licheniformis, lactobacillus plantarum, enterococcus faecalis and lactobacillus acidophilus; the six probiotics are subjected to independent solid fermentation, the prepared fermentation fungus materials are compounded in proportion to obtain a compound fermentation fungus material, and the compound fermentation fungus material is fed according to cows with different weights. Through the technical route of single-bacterium independent fermentation, the problem of mutual inhibition generated during compound fermentation of various strains is avoided, high-density propagation of the strains in the fermentation process is guaranteed, the compounded feed can meet the nutritional requirements of cattle in different stages, and the yield of the cattle is improved. The feed digestion and absorption rate is effectively improved, the cattle immunity is enhanced, and the growth performance is promoted.

The application discloses a chimeric antigen receptor-macrophage targeting HSP70 and application thereof in the treatment of noise-induced hearing loss, wherein the extracellular domain of the chimeric antigen receptor targeting HSP70 comprises an HSP70 specific binding fragment, and the intracellular domain comprises an IL-4 signal pathway functional element, forming a'signal switch type' CAR structure targeting HSP70, which can be used for preparing the chimeric antigen receptor-macrophage targeting HSP70 and mediating the polarization of the macrophage to M2 type and exerting the anti-inflammatory function. It has been verified that the chimeric antigen receptor-macrophage targeting HSP70 can specifically respond to the inner ear inflammatory microenvironment, switch the anti-inflammatory phenotype and protect the hair cells and auditory nerves, and can be used for treating the noise-induced hearing loss, breaking through the limitation of the symptomatic support treatment of the traditional hearing aid device and having a significant application prospect.

The invention relates to the field of kitchen supplies, and discloses a burner and a stove. The combustor comprises a combustion main body, the combustion main body is provided with a flow channel and an air inlet communicated with the flow channel, the flow channel is used for mixing fuel gas and air, and the combustion main body is further provided with an air outlet circular seam communicated with the flow channel; the gas outlet circular seam spirally and continuously extends around the central axis of the combustion main body in the height direction of the combustion main body, the spiral track of the gas outlet circular seam rises along with the extension and gets close to the central axis of the combustion main body, and the vertical height of the gas outlet circular seam rises along with the spiral track getting close to the central axis. According to the technical scheme, sufficient combustion of gas can be achieved, and the combustion efficiency and heat efficiency of the stove are remarkably improved.