27results about How to "Avoid inhibition" patented technology

This application discloses a method and apparatus for constructing a multi-scale adaptive gating MambaPlus network, belonging to the field of artificial intelligence and machine learning technology. The method includes: initializing the network configuration and constructing the basic structure; preprocessing the input data to generate a standard dataset; mapping the input data to the hidden space via an input mapping layer, and extracting backbone features from the Mamba backbone; constructing at least two parallel scale branches in the hidden space to obtain a multi-scale feature set; inputting the backbone features and multi-scale features into an adaptive gating module, dynamically allocating weights and adaptively fusing them through a hierarchical gating mechanism to generate fused features; further enhancing the features through cross-scale attention and feedforward enhancement, and then superimposing the residuals to generate the final discriminative features; finally, completing category prediction and model training evaluation. This application, while retaining the advantages of Mamba's long-range dependency modeling, addresses the problems of insufficient utilization of multi-scale information, poor adaptive feature fusion, and low robustness in complex scenarios.

The invention relates to the technical field of immune carriers, in particular to immune carrier microspheres loaded with individualized MHC-II binding polypeptide and vaccine preparation and application of the immune carrier microspheres loaded with the individualized MHC-II binding polypeptide. The core microsphere is loaded with individualized MHC-II binding polypeptide, the sequence of the MHC-II binding polypeptide is obtained by predicting and screening based on an HLA genotyping result, and each HLA allele corresponds to at least one high-affinity MHC-II binding polypeptide; and the shell is a glucan or other polymer coating layer. The preparation method has the advantages that the T epitope and the B epitope are separately subjected to immune competitive inhibition inside and outside the microspheres, so that a better immune effect is obtained. The antibody avoids cross reaction side effects; carrier molecule diversity is reduced, and side effects caused by T cell over-activation are avoided; th1 epitopes and Th2 epitopes can be contained in the microspheres, so that antibody immunity and T cell immunity functions are generated; the particle size of the microspheres is controllable, and the immunologic function can be achieved without adjuvants.

The invention discloses a sewage plant tail water treatment system and method, and relates to the technical field of sewage treatment.The sewage plant tail water treatment system is applied to tail water generated by a sewage plant adopting an ozone advanced oxidation technology, and the treatment system comprises an activated carbon reaction device, a denitrification reaction device, an ecological pond and a horizontal subsurface flow wetland; the activated carbon reaction device is communicated with the tail water pipe and comprises an activated carbon filtering layer, and the activated carbon filtering layer is used for adsorbing chemical oxygen demand and dissolved oxygen in tail water; the denitrification reaction device is communicated with the activated carbon reaction device and comprises a denitrification filter material layer, and the denitrification filter material layer is used for autotrophic denitrification nitrogen removal of tail water; the ecological pond is communicated with the denitrification reaction device and comprises aquatic plants and aquatic animals; the horizontal subsurface flow wetland is communicated with the ecological pond and is used for deeply filtering the tail water. The treatment system can improve the purification effect of the tail water of the sewage plant.

This application discloses an electronic atomized product and a method for determining its nicotine content. The nicotine content in this electronic atomized product is no higher than 500 ng / g, simulating the action and visual experience of smoking, assisting users in adapting to the transition phase without nicotine dependence, and aiding in smoking cessation. The method for determining the nicotine content in the electronic atomized product includes: ultrasonic extraction of the sample using ultrapure water; liquid chromatography separation using an alkaline aqueous phase (pH 9.22–10.76) and acetonitrile as the mobile phase; positive ion ionization using an electrospray ionization source; and detection of nicotine characteristic ions using a single quadrupole mass spectrometer in selected ion monitoring mode, achieving highly sensitive, highly selective, low-cost, stable, and reliable quantitative analysis of nicotine content.

This disclosure relates to a voice call processing method, circuit, apparatus, medium, chip, and terminal, belonging to the field of electronic technology, and can improve the sensitivity of signals used for proximity detection. A voice call processing method includes: during a voice call at the terminal, receiving a sampled signal acquired by the terminal's microphone, wherein the sampled signal includes a first voice signal and a proximity detection signal for proximity detection; filtering the sampled signal to remove the first voice signal and obtain the proximity detection signal; amplifying the filtered proximity detection signal; performing analog-to-digital conversion on the amplified proximity detection signal; and determining a proximity detection result based on the analog-to-digital converted proximity detection signal.

The present application relates to the technical field of pulping and papermaking, and provides a composite biological enzyme assisted low-energy consumption pulping method.The method comprises the following steps: S100, pretreating raw materials, adding a composite biological enzyme preparation and a softening agent, and performing softening treatment to obtain a mixture; S200, mechanically pulping the mixture, performing filament separation treatment through a rubbing equipment, and forming a pulp liquid; S300, performing bleaching treatment and cleaning treatment on the pulp liquid, and completing the pulping process; wherein the composite biological enzyme preparation comprises laccase, cellulase, xylanase, pectinase and magnetic particles.The composite biological enzyme preparation can reduce the energy consumption in the pulping process, helps to reduce the production cost, improves the production efficiency, replaces the traditional chemical agent with the composite biological enzyme preparation, reduces the environmental pollution, effectively improves the decomposition rate of plant fibers, makes the pulp more easily obtained, and improves the utilization rate of raw materials.

The invention discloses a single-bacterium fermentation compounding method of cattle feed, and relates to the technical field of feed fermentation. Comprising the following steps: preparing a single-bacterium fermentation bacterial material, the single-bacterium fermentation bacterial material comprises 42.25-47.25 parts of wheat bran, 19-21 parts of soybean meal, 14.25-15.75 parts of corn flour, 19-21 parts of rice hull powder and 0.003-0.005 part of a bacterial liquid, and strains used by the bacterial liquid comprise six probiotics including saccharomyces cerevisiae, bacillus subtilis, bacillus licheniformis, lactobacillus plantarum, enterococcus faecalis and lactobacillus acidophilus; the six probiotics are subjected to independent solid fermentation, the prepared fermentation fungus materials are compounded in proportion to obtain a compound fermentation fungus material, and the compound fermentation fungus material is fed according to cows with different weights. Through the technical route of single-bacterium independent fermentation, the problem of mutual inhibition generated during compound fermentation of various strains is avoided, high-density propagation of the strains in the fermentation process is guaranteed, the compounded feed can meet the nutritional requirements of cattle in different stages, and the yield of the cattle is improved. The feed digestion and absorption rate is effectively improved, the cattle immunity is enhanced, and the growth performance is promoted.

The application discloses a chimeric antigen receptor-macrophage targeting HSP70 and application thereof in the treatment of noise-induced hearing loss, wherein the extracellular domain of the chimeric antigen receptor targeting HSP70 comprises an HSP70 specific binding fragment, and the intracellular domain comprises an IL-4 signal pathway functional element, forming a'signal switch type' CAR structure targeting HSP70, which can be used for preparing the chimeric antigen receptor-macrophage targeting HSP70 and mediating the polarization of the macrophage to M2 type and exerting the anti-inflammatory function. It has been verified that the chimeric antigen receptor-macrophage targeting HSP70 can specifically respond to the inner ear inflammatory microenvironment, switch the anti-inflammatory phenotype and protect the hair cells and auditory nerves, and can be used for treating the noise-induced hearing loss, breaking through the limitation of the symptomatic support treatment of the traditional hearing aid device and having a significant application prospect.

The invention relates to the field of kitchen supplies, and discloses a burner and a stove. The combustor comprises a combustion main body, the combustion main body is provided with a flow channel and an air inlet communicated with the flow channel, the flow channel is used for mixing fuel gas and air, and the combustion main body is further provided with an air outlet circular seam communicated with the flow channel; the gas outlet circular seam spirally and continuously extends around the central axis of the combustion main body in the height direction of the combustion main body, the spiral track of the gas outlet circular seam rises along with the extension and gets close to the central axis of the combustion main body, and the vertical height of the gas outlet circular seam rises along with the spiral track getting close to the central axis. According to the technical scheme, sufficient combustion of gas can be achieved, and the combustion efficiency and heat efficiency of the stove are remarkably improved.

The embodiment of the specification provides a data alarm system, a processing method, electronic equipment and a storage medium, and relates to the technical field of network security data processing. The system comprises: a pattern recognition module, configured to generate dynamic intelligence sequences with a space-time correlation relationship according to alarm information of different sources, and recognize a dominant interaction mode of a current attack; a blocking probability determination module, configured to determine an alarm correlation link, and determine a local information blocking probability according to information continuity between adjacent intelligence frames in the alarm correlation link and a change frequency of the dominant interaction mode; a compensation factor determination module, configured to generate a compensation factor based on alarm handling channel information and based on network interaction characteristics; and a deployment processing module, configured to adjust a resource quota of an alarm handling channel and an alarm aggregation determination threshold according to the compensation factor in each preset deployment period. Based on this, adaptive reduction of redundant alarms can be realized, and security operation efficiency and protection accuracy can be improved.

This invention discloses a composite admixture and its preparation method, as well as a method for preparing concrete pipe piles. The composite admixture comprises submicron-sized metakaolin, ultrafine quartz sand powder, slag powder, calcium formate, sulfate activator, water-retaining and toughening component, auxiliary setting regulator component, and superplasticizer; wherein, by weight percentage, the submicron-sized metakaolin is 12%-18%, the ultrafine quartz sand powder is 22%-30%, the slag powder is 35%-45%, the calcium formate is 2.5%-4.0%, the sulfate activator is 7%-11%, and the water-retaining and toughening component is 2.0%-4.0%; the median particle size D50 of the submicron-sized metakaolin is 1.0μm-3.0μm, and the specific surface area is ≥1200m² / kg; the water-retaining and toughening component is a mixture of redispersible latex powder and cellulose ether in a mass ratio of (2:1)-(1:1). This invention, through multi-component synergy, significantly improves the early strength, later strength, durability, and crack resistance of concrete under low-temperature steam curing conditions of 40℃-60℃, which can simultaneously meet the differentiated performance requirements of PHC piles and large-diameter pipe piles, and greatly reduce production energy consumption.

The invention provides a machining cutting control monitoring system and method. A target machining posture section is recognized through a preset machining path of a cutting robot; a machining point position corresponding to the minimum static rigidity value is selected from the target machining posture section to serve as a calibration point, so that a main shaft in an end effector of the cutting robot operates at a plurality of preset idle rotating speeds at the calibration point, and vibration acceleration signals are collected; extracting a dominant modal frequency from the vibration acceleration signal, and performing processing attitude association analysis on the calibration point based on the dominant modal frequency and the static stiffness value at the calibration point to obtain a stability lobe graph associated with the processing attitude of the calibration point; and an optimal cutting parameter combination is matched for the target machining posture section associated with the calibration point according to the stability lobe graph, and when the cutting robot moves to the target machining posture section, the optimal cutting parameter combination is called for cutting. According to the technical scheme provided by the invention, the cutting robot can accurately cut the cutting machining surface under the cutting chatter.

This invention discloses a flotation separation method for collecting galena and inhibiting sphalerite and pyrite, achieving efficient separation of galena from sphalerite and pyrite in a low-alkaline pulp environment, belonging to the field of mineral beneficiation technology. This invention uses N-hydroxyethylethylenediaminetriacetic acid as an inhibitor of sphalerite and pyrite at a low alkalinity of pH 7.5-9.5, and one or two of sodium diethyldithiocarbamate, sodium ethyl xanthate, and xylenol dithiophosphate as collectors for galena. Under low dosage conditions, it achieves simultaneous inhibition of sphalerite and pyrite and effective collection of galena, offering advantages of high efficiency, simple process, economy, and environmental friendliness. It is particularly suitable for silver-bearing, high-sulfur, low-grade lead-zinc ores and has broad application prospects.

The invention relates to a semi-coke wastewater double-carbon-source biochemical treatment system and process, and the process comprises the following steps: pretreated semi-coke wastewater enters a front anoxic tank for denitrification reaction to remove COD and total nitrogen; effluent of the front anoxic tank enters an aerobic tank to be subjected to carbonization and nitration reaction, organic matters are removed, and ammonia nitrogen is converted into nitrite nitrogen and nitrate nitrogen; effluent of the aerobic tank enters a rear anoxic pretreatment tank for endogenous denitrification reaction; the mixed liquid in the rear anoxic pretreatment tank flows back to the front anoxic tank, and the reflux ratio is 400%-800%; and effluent of the post-anoxic pretreatment tank is subjected to mud-water separation and post-treatment to reach the standard and then is recycled. Mixed liquid backflow is carried out at the tail end of the rear anoxic pretreatment tank, the device has the advantages of being resistant to toxicity and impact, simple in technological process and low in operation cost, meanwhile, a large backflow ratio is adopted, nitrate nitrogen is removed, and meanwhile impact of biotoxicity on a biochemical system and inhibition of the biotoxicity on microorganisms are reduced.

The application discloses an exosome preparation for treating hypofunction of ovary and a preparation method and application thereof, and belongs to the technical field of biological medicine, and particularly relates to a preparation method of an exosome preparation for treating hypofunction of ovary, which comprises the following steps: taking perinatal stem cells, subculturing, obtaining domesticated perinatal stem cells, digesting, expanding and culturing to a density of 80%-85%, adding a culture medium for culturing, collecting supernatant, collecting supernatant for 3 times, combining, filtering through a 0.45 mu m PES filter membrane first, and then concentrating to obtain a concentrated solution; centrifuging, resuspending a precipitate, purifying through a density gradient, obtaining an exosome precipitate, and suspending the exosome precipitate in a cryopreservation protective solution to obtain the exosome preparation. The application provides the exosome preparation for treating hypofunction of ovary and the preparation method and application thereof, a safe, sufficient, high-purity and stable exosome preparation is prepared, and the stem cell exosome for treating hypofunction of ovary is provided.

The invention discloses a complete mixing continuous flow anaerobic ammonia oxidation sludge reinforced granulation device and method, and belongs to the technical field of wastewater biological denitrification. The device takes a complete mixing continuous flow reactor as a core, and is provided with a monitoring control platform, a temperature control device, a pH regulating agent tank and a nutrient solution agent tank. A magnetic suspension stirring device is arranged at the bottom of the reactor and comprises a stirring rotor arranged in an inner cavity of the reactor and a magnetic suspension motor fixed to the outer side of the bottom of the reactor, the magnetic suspension motor drives the stirring rotor to rotate in a magnetic coupling mode without a penetrating shaft, and a strict anaerobic and high-shear mixing environment is constructed for anaerobic ammonium oxidation bacteria. A detachable sludge blocking baffle is arranged on an effluent weir at the upper part of the reactor, and sieve plates with different apertures can be replaced according to operation stages, so that efficient interception and backflow of granular sludge with different particle sizes under a continuous flow condition are realized. On-line monitoring and automatic control are integrated, the anaerobic ammonia oxidation sludge granulation process is effectively promoted, and it is guaranteed that the system stably runs for a long time under the continuous flow condition.

The utility model relates to the technical field of sewage treatment, in particular to a low-temperature quality-divided treatment device for domestic sewage in villages and towns, which comprises a quality-divided box, the interior of the quality-divided box is divided into a black water cavity and a grey water cavity, water inlet pipes with pumps are arranged on the upper side walls of the black water cavity and the grey water cavity, a heating pipe is arranged on the side wall of the black water cavity, and a water outlet pipe is arranged on the side wall of the grey water cavity. An air outlet pipe is arranged at one end of the side wall of the black water cavity, a control valve assembly is arranged on the air outlet pipe, a filtering assembly is arranged on the upper side wall of the grey water cavity, the upper end of the filtering assembly is connected with the water inlet pipe, a connecting pipe is arranged on one side wall of the grey water cavity, and a purifying box is arranged at one end of the connecting pipe; a purifying assembly is arranged in the purifying box, a water outlet pipe is arranged at one end of the purifying box, the filtering assembly comprises a fixing box and a sundry drawer, the purifying assembly comprises a rotating motor, a rotating rod and purifying blades, and meanwhile collaborative recycling of organic energy (biogas) and recycled water is achieved.

This invention discloses a flotation process for high-oxidation-rate copper ore, comprising: staged flotation of copper sulfide and copper oxide to obtain copper sulfide and easily floatable copper oxide concentrates; then flotation desliming to obtain low-grade copper-bearing slime; and stepwise flotation of copper oxide after desliming to obtain copper oxide concentrate. This invention adds a sulfiding agent during the grinding process to activate the copper oxide before flotation, improving its floatability. During the copper sulfide flotation process, both copper sulfide and easily activated copper oxide float, resulting in copper sulfide and easily floatable copper oxide concentrates. High-oxidation-rate copper ore contains easily floatable copper sulfide and easily floatable, moderately floatable, and difficult-to-float copper oxides. This invention, during the flotation process, stages activation and separation of easily floatable, moderately floatable, and difficult-to-float copper oxides, avoiding the inhibitory effect of excessive sodium hydrosulfide on some copper minerals and improving the recovery rate of these copper minerals.

The invention provides a manioc waste liquid feed preparation process based on microbial fermentation, and belongs to the technical field of feed. According to the application, the nano calcium phosphate loaded high-valence ferric salt and the metal ion doped hydroxyapatite are introduced to solve the problems of excessive metal ions and anti-nutrient substance residues; the nano calcium phosphate loaded high-valence ferric salt efficiently oxidizes and removes cyanide ions and tannin in the fermentation liquor through ferrate loaded on the surface; oxidation products and part of ferric ions are fixed, so that inhibition on microorganisms is avoided; the metal ion-doped hydroxyapatite effectively captures excessive metal ions through ion exchange and complexation, reduces the free concentration of the metal ions, prevents adverse effects on microbial metabolism, can compete with anions in a fermentation liquid, inhibits the generation of toxic complexes, and reduces the toxicity to a fermentation system; the synergistic effect of removal of anti-nutrient substances and dynamic regulation and control of metal ions is achieved, and the nutritional value and safety of the final feed are improved.

The invention relates to the technical field of heat conduction materials, in particular to low-heat-resistance low-oil-permeability anti-aging thixotropic high-heat-conduction silicone grease and a preparation method thereof. According to the silicone grease, dimethyl silicone oil and vinyl-terminated polydimethylsiloxane serve as matrixes, layered interface modified spherical aluminum oxide and flaky boron nitride are compounded to serve as heat conduction filler, and hydrophobic fumed silica and a fixed-point micro-crosslinking system are added. Through a process of firstly constructing a heat-conducting network and then triggering sparse crosslinking, high heat conductivity coefficient, low interface thermal resistance, good thixotropy and long-term thermal stability are realized, the problems of oil leakage, sedimentation and aging under high filling are effectively solved, and the composite material is suitable for heat dissipation of high-power electronic devices.

This invention provides a method and system for reducing the color of coking wastewater concentrate, belonging to the field of wastewater treatment. It aims to solve the problems of incomplete decolorization and easy color reversion that exist when using advanced oxidation methods to decolorize coking wastewater concentrate. The method includes: Step 1, adding persulfate to the wastewater to carry out a first-step reaction, obtaining a primary treated liquid; Step 2, transferring the primary treated liquid to an irradiation device for irradiation treatment, obtaining a secondary treated liquid; Step 3, collecting the ozone generated in the irradiation device and the secondary treated liquid respectively, and introducing the ozone into the secondary treated liquid, and adding ferrous salt, to carry out a final reaction, so that the color of the wastewater is reduced to less than 10 times.

The invention discloses a multi-source biological fermentation wastewater treatment method, system and equipment and a storage medium, and relates to the technical field of environmental engineering and wastewater treatment.The method comprises the steps that biological fermentation wastewater with different concentrations is collected to corresponding collecting pools, and water quality parameters of the collecting pools are monitored in real time; according to the monitored water quality parameters, the mixing proportion of the biological fermentation wastewater with all the concentrations is adjusted according to a preset proportion through an automatic control system, and the pH value of the mixed biological fermentation wastewater is adjusted; pumping the adjusted wastewater into a unitized anaerobic reactor for multilayer biological anaerobic treatment; the effluent subjected to anaerobic treatment sequentially passes through an A / O system and an aerobic biochemical system to be subjected to carbon-nitrogen synergistic degradation and mud-water separation. The method disclosed by the invention has the beneficial effects that the biological fermentation wastewater with different concentrations is efficiently and cooperatively treated, the effluent quality is improved, the energy consumption is reduced, and sludge recycling and stable operation of the system are realized.

The invention discloses an improved BM3D image denoising method based on multi-element fusion block similarity measurement. According to the method, wavelet decomposition is carried out on a noise image, a noise standard deviation is stably estimated on a highest-frequency sub-band, BM3D parameters are initialized, in a basic estimation stage, pixel intensity, local variance and gradient difference are fused to construct block similarity measurement, similar block matching grouping and three-dimensional block group construction are realized, and the method has the advantages of being high in robustness and high in robustness. And in a final estimation stage, a basic estimation image is obtained through three-dimensional collaborative hard threshold filtering and weighted aggregation, in the final estimation stage, secondary matching is guided by the basic estimation image, a three-dimensional block group is constructed again, a structure and texture adjustment factor is introduced to form an adaptive Wiener coefficient for Wiener collaborative filtering, and finally, a target de-noised image is output through weighted aggregation. In the whole process, the phenomena of mismatching and over-smoothing of a traditional BM3D algorithm under the condition of high noise can be reduced, the edge and texture detail keeping capability is enhanced, and the denoising quality of a noise image is improved.

The invention relates to the technical field of biology, in particular to a method for improving the ring opening rate of monascus milovastatin through enzymolysis treatment, which comprises the following steps: preparing a pH response type functional carrier, activating carboxyl on the surface of the carrier, covalently immobilizing esterase, extracting and purifying lovastatin lactone, catalyzing ring opening by immobilized enzyme, recovering the immobilized enzyme and purifying lovastatin ring-opening acid. According to the scheme, the pH response type modified carrier is constructed to immobilize esterase, the reversible ionization characteristic of carboxyl functional groups of the carrier is utilized to realize accurate regulation and control of an enzymolysis microenvironment, the pH response carrier can present a dynamic swelling-shrinking behavior in different reaction stages, and the reaction process can be accelerated through a substrate enrichment effect in the initial reaction stage; accumulated products can be dredged through the swelling effect in the middle stage of the reaction; in the self-regulation stage, the stability of the microenvironment in which the enzyme is located can be maintained through contraction, so that the ring-opening conversion effect is greatly improved, the enzyme always keeps relatively high activity in a relatively long reaction period, and the ring-opening rate of the monascus milovastatin is greatly increased.

The present application relates to the field of genetic engineering and enzyme catalysis, and discloses a one-pot two-enzyme tandem catalytic synthesis method of unnatural chiral alpha-amino acid. The present application provides a method, which adds decarboxylase (AnFdc Ubix ), ammonia-lyase (LsPAL), ammonium carbamate and ammonium bicarbonate into an aqueous phase, so that a substrate olefin is carboxylated under the catalysis of decarboxylase (AnFdc Ubix ), and then alpha-amino acid with 99% ee value is obtained through the catalysis of ammonia-lyase (LsPAL). The one-pot method can avoid the step of intermediate product separation, and the produced intermediate is converted into the product alpha-amino acid, thereby avoiding the problem of product inhibition. The method provided by the present application has high yield in preparing alpha-amino acid. In addition, the method can be applied to the synthesis of L-phenylalanine and derivatives, and has great application value and market prospect.

The application belongs to the technical field of natural product extraction and nanometer material preparation, and specifically discloses an enzyme-assisted green extraction and nanometer modification method of active polysaccharide of traditional Chinese medicinal materials. In the extraction stage, a three-stage biomimetic gradient layering degradation strategy is adopted to target the wall breaking, and subcritical water extraction is coupled to realize efficient release of polysaccharide, so that the extraction rate reaches 18-25%, and the purity is 85-95%. In the nanometer stage, the polysaccharide, chitosan, sodium alginate and tea polyphenol are constructed into core-shell type nanoparticles (50-200 nm) through ultrasonic driving layer-by-layer self-assembly, the water solubility of the polysaccharide is increased by 3-5 times, the thermal stability is increased by 30-45 DEG C, and the oral absorption rate is increased by more than 2 times.

The invention belongs to the technical field of biology, and particularly discloses a method for rapidly enriching caproic acid bacteria from white wine pit mud. The method comprises the following steps: adding normal saline into the white wine pit mud, and uniformly mixing to obtain pit mud suspension; performing constant-temperature water bath treatment on the pit mud suspension, inoculating and transferring the pit mud suspension into a saline bottle filled with a special ES culture medium, and performing constant-temperature culture; putting the cultured fermentation liquor into a test tube, carrying out constant-temperature water bath treatment, then inoculating into a saline bottle filled with a special ES culture medium, and carrying out constant-temperature culture; and repeating the steps, and subculturing to the third generation to the fourth generation to obtain the stable caproic acid-producing microbial flora. According to the method, the microbial community structure is optimized through heat treatment, specific guiding factors are combined, the ethanol utilization type caproic acid producing bacteria with Clostridium kluyveri as the main functional bacteria can be efficiently and directionally enriched, operation is easy and convenient, the period is short, the obtained flora is high in stability, the caproic acid yield is high, and the method is suitable for follow-up enlarged culture and large-scale intensified application in baijiu brewing.