The application relates to a
system and method for analyzing and detecting
cell deformation characteristics in microdroplets, belonging to the field of microfluidic technology. The
system comprises a
microscopic imaging module, a
data processing module, a capillary microchannel, a sample
injection pump and a collection device; the microchannel is placed above a
microscope object platform, a coaxial microchannel is adopted, a
cell suspension is introduced into an inner tube, a continuous phase fluid is introduced into an outer tube, cells are wrapped in the suspension, the size of the droplet and the number of wrapped cells are controlled by changing the
flow ratio, an outlet is connected with the collection device, and the collection device is used for collecting the detected cells and waste liquid; the capillary microchannel realizes mechanical
extrusion of the cells in the microdroplets. The
data processing module is connected with a
microscope camera and is used for identifying the
size change of the cells and analyzing the deformation characteristics according to characteristic parameters. The application generates cells wrapped by droplets in the microchannel and makes the cells pass through a narrow contraction area, analyzes the influence of the contraction area on the deformation of the cells in the microdroplets, and can realize efficient and accurate detection of the deformation of the cells in the microdroplets.