141 results about "Phase imaging" patented technology

The invention discloses a single-pixel phase imaging method, system and device and a storage medium, and the imaging system comprises a light source, a preprocessing module, a first spatial modulator, a second spatial modulator, a lens, a detector, a data collection card and a processor. After passing through the first spatial modulator, the measured object, the second spatial modulator and the lens in sequence, the light reaches the detector; the imaging method comprises the following steps: acquiring a first hologram and a second hologram which differ from a preset phase shift, calculating a hologram of a measured object according to the first hologram, the second hologram and a preset calculation formula, and calculating a reconstructed image of the measured object according to the hologram of the measured object and a preset algorithm. The embodiment of the invention improves the efficiency of phase shift holographic imaging, and can be widely applied to the technical field of imaging.

The invention relates to the technical field of large-aperture telescope construction, in particular to a large-aperture spliced telescope progressive generation method, which comprises the following steps of S1, constructing a local co-phase region at the edge of a large-aperture telescope by using spliced sub-mirrors through assistance of a small-aperture secondary mirror, and forming local co-phase imaging capability; s2, the step S1 is repeated, and equal-area local co-phase regions are constructed at the symmetrical positions of the edge of the large-aperture telescope; s3, constructing an interference imaging system through optical path difference adjustment, zero interference elimination and two symmetrical local co-phase regions; s4, repeating the steps S1 to S3, constructing more symmetrical and equal-area local co-phase regions at the edge of the large-aperture telescope, and constructing interference imaging in which the plurality of symmetrical local co-phase regions participate; and S5, constructing local co-phase regions in sequence from the edge to the center until the construction of the whole large-aperture telescope is completed.

A method, a system, and computer program product for optical systems including a metasurface that supports quantitative phase imaging are provided. Optical system characteristics of an optical system are received. The optical system characteristics include an optical path, the optical system comprising a light source and an imaging system. Optical parameters of at least one metasurface are received. A location of the metasurface is selected within the optical path of the optical system to modulate an incident wavefront generated by the light source. An image acquired by the imaging system is processed, based on the optical parameters of the at least one metasurface and based on the location of the metasurface within the optical path, to determine one or more image properties.

Snapshot phase-shifting diffraction modules and associated systems and methods are described that enable high spatial and temporal resolution phase imaging with high immunity to environmental factors such as vibrations and temperature changes. One example optical diffraction phase module includes a polarization grating to produce two circularly polarized light beams with opposite polarizations, a first lens to receive the two circularly polarized beams, and a spatial filter positioned at a focal plane of the first lens. The spatial filter includes two openings, one to spatially filter one of the two circularly polarized light beams, and another opening to allow another circularly polarized light beam to pass. The module also includes a second lens to focus the received light onto an image plane and to enable a phase measurement based a plurality of interferograms. The phase module can be incorporated into a microscope system that operates a reflection or a transmission mode.

The invention relates to a system and a method for dual-view quantitative phase imaging and honeycomb artifact removal based on multi-core optical fiber transmission. The system comprises a light source, a pinhole aperture, a condensing mirror, a spatial light modulator, a mirror, a multi-core optical fiber, an objective lens, a tube lens, a spectroscope, a first CMOS camera and a second CMOS camera. According to the multi-core optical fiber transmission-based system for dual-view quantitative phase imaging and honeycomb artifact removal, the phase distortion of the multi-core optical fiber is corrected through the spatial light modulator, different illumination angles are generated by using the spectroscope, and the transmission characteristics of the multi-core optical fiber are combined, so that the dual-view quantitative phase imaging and honeycomb artifact removal can be realized on the premise of not changing the position of a sample. According to the method, phase information under two different visual angles is rapidly acquired, and then the two groups of data are processed by using the following method, so that three-dimensional reconstruction is realized, and the imaging depth and accuracy are improved.

The invention discloses a high-order non-interference quantitative phase imaging system and method based on single exposure, and belongs to the technical field of optical microscopic imaging. The microscope module comprises a halogen lamp, a condenser, an annular diaphragm, a sample, an objective lens, a phase plate, a lens I, a reflector and a lens II which are sequentially arranged along the light beam propagation direction, and the light splitting modulation module comprises a lens III, a light splitting module I, a light splitting module II, a spatial light modulator, a lens IV and a CMOS camera which are sequentially arranged along the light beam propagation direction. By adopting the single-exposure-based high-order non-interference quantitative phase imaging system, the advantages of stable structure, insensitivity to environmental interference, high phase sensitivity, low spatial noise and the like of a white light illumination system are reserved.

The invention relates to a thick-wall pressure vessel inner wall damage detection method based on a low-frequency ultrasonic phase control imaging algorithm, which comprises the following steps: calculating to obtain an ultrasonic Lamb wave frequency dispersion curve of a thick-wall plate-shaped structure, and selecting a low-frequency guided wave frequency; determining parameter configuration of array elements of the phased array according to the low-frequency guided wave frequency, and arranging the array elements on the outer wall of the pressure vessel; exciting a low-frequency Lamb wave signal, and collecting FMC data through phased array elements, including echo signal data of each array element; frequency dispersion compensation processing is carried out on the acquired FMC data, and a phase coherence factor of each imaging pixel point is calculated; and adopting a TFM (Time Frequency Modulation) algorithm based on phase coherence factor weighting to carry out delay weighted reconstruction on the compensated FMC data to obtain an imaging and positioning result of the damage defect of the inner wall of the pressure vessel. Compared with the prior art, the problems of guided wave propagation frequency dispersion effect, complex mode, low signal-to-noise ratio and the like can be solved, and high-precision imaging positioning of inner wall damage defects is realized.

The invention discloses a variable view field Linnik interference microscopic system and a measurement method thereof, and belongs to the field of laser measurement instruments, and a variable diaphragm is introduced into a reference arm of an interference system to realize matching of objective lenses of different test arms, so that light field spatial correlation under speckle illumination is maintained; meanwhile, a light source system with a delay line structure is adopted to accurately compensate the optical path difference introduced by the asymmetric objective lens configuration, so that the acquisition of a high-contrast interference pattern is realized. The method can effectively improve the quality of an interference image, has a depth selection function, and is suitable for dynamic phase imaging in different view field ranges. The technical scheme of the invention shows good imaging effect and adaptability in the aspects of dynamic imaging and depth layering.

The invention discloses a single-pixel phase imaging method based on an untrained physical driving neural network, and belongs to the field of single-pixel imaging and computational optics. According to the method, by adding a physical diffraction layer and an Admn optimizer, direct reconstruction from a single-pixel detection intensity sequence to a phase object image is realized. According to the method, pre-training is not needed, and the dependency on a large data set is remarkably reduced; by introducing the total variation loss of the output phase, the influence of noise and optical distortion is effectively suppressed; and when the sampling rate is as low as 30%, the phase distribution can still be efficiently reconstructed, and the required sampling number is reduced.

An X-ray phase imaging apparatus includes a control device configured or programmed to make a notification prompting a user to update or generate a corresponding second X-ray image when determining that a decrease in an image quality of an X-ray phase contrast image generated based on a first X-ray image obtained by imaging a subject and a second X-ray image obtained by imaging without the subject arranged does not fall within a predetermined allowable range and / or determining that the second X-ray image associated with an imaging condition has not been stored.

The invention belongs to the technical field of optical measurement, and particularly relates to a digital holographic microscopy system phase distortion correction method based on adaptive optics, which has the advantage that optical wave complex amplitude information can be acquired in a wide field by means of digital holographic microscopy, and uses a distortion phase image measured by a digital holographic microscopy system as input to correct phase distortion of the digital holographic microscopy system. And iterating the image by using an optimization algorithm until the image evaluation function converges, and obtaining a correction pattern for removing phase distortion. And uploading the correction pattern to a self-adaptive correction device and modulating the wavefront of the light wave to finally realize accurate compensation of phase distortion. The method can provide an in-situ, accurate and rapid phase distortion correction mode and means for the field of optical microscopic imaging, especially the field of quantitative phase imaging.

An ultra-high flux quantitative phase imaging (QPI) system incorporates a real-time rotating cell detection based platform with concentric annular cell chambers (20). Each chamber (20) has a detection region (22) and a pair of access channels (24) with openings (25) between the ends. The access channel (24) serves to deliver a fluid containing the cell sample introduced into the opening (25) to the detection region (22). The opening (25) faces an inner radial position of the rotating platform compared to the detection area (22) so as to prevent liquid within the detection area (22) from being squeezed out by centrifugal force when the platform rotates, while communicating with the external environment before, during and after rotation.

Quantitative phase imaging (QPI) is a label-free computational imaging technique that provides optical path length information of objects. Here, a diffractive QPI network architecture is disclosed that can synthesize the quantitative phase image of an object by converting the input phase information of a scene or object(s) into intensity variations at the output plane. A diffractive QPI network is a specialized all-optical device designed to perform a quantitative phase-to-intensity transformation through passive diffractive / reflective surfaces that are spatially engineered using deep learning and image data. Forming a compact, all-optical network that axially extends only ˜200-300λ (λ=illumination wavelength), this framework replaces traditional QPI systems and related digital computational burdens with a set of passive substrate layers. All-optical diffractive QPI networks can potentially enable power-efficient, high frame-rate and compact phase imaging systems that might be useful for various applications, including, e.g., on-chip microscopy and sensing.

The invention discloses a microfluidic image flow cytometry identification system and a microfluidic image flow cytometry identification method based on multi-modal phase imaging and deep learning, relates to a microfluidic image flow cytometry detection technology, and belongs to the crossing field of microfluidics, optical imaging and artificial intelligence. The cell deformation chip is used for inducing a cell sample to generate controllable deformation through the cell deformation chip and discharging deformed cells; the optical imaging unit is used for scanning the deformed cells and collecting multi-modal phase images of the deformed cells; the data processing and analysis unit is used for preprocessing the multi-modal phase image and performing cell intelligent identification analysis on the preprocessed multi-modal phase image by using a deep learning feature extraction network, so that accurate identification and classification of cells are realized, and a leukocyte subpopulation identification model is constructed; and generating a cell imaging result and a cell mechanical parameter thermodynamic diagram. According to the invention, label-free identification of leukocyte subgroups is realized, and the problems of tedious operation and cell damage of traditional fluorescence labeling are solved.

Optically computed phase imaging systems and methods are provided. An example system includes an interferometer configured to output 3D spatial-spectral data of a sample including an interferometric signal and an optical computation assembly having a spatial light modulator configured to modulate the 3D spatial-spectral data with a modulation pattern. The modulation pattern modulates the interferometric signal along a spectral dimension to select a depth to obtain a sample signal at the selected depth and modulates the interferometric signal along a first spatial dimension to create a waveform to facilitate phase extraction. The system further includes a detector configured to detect 2D spatial data of the sample. The system further includes a processor coupled to a memory, the processor configured to process the 2D spatial data to extract phase information of the sample.

The invention discloses a 30-40GHz near-field millimeter wave imaging method based on phase imaging, and relates to the field of nondestructive testing. According to the near-field millimeter wave phase imaging method, a phase imaging technology and a near-field millimeter wave imaging method are combined, the characteristics of a detected sample are reconstructed through the phase effect, and the limitation that the detected sample is inversed only from the amplitude in a traditional near-field millimeter wave imaging method is overcome. The method is based on a phase imaging technology, and utilizes a near-field millimeter wave synthetic aperture technology and the phase imaging technology to convert back scattering data into wrapped phase data. And then, carrying out de-noising processing on the wrapped phase data through the corrected mean filter. Then, the wrapped phase data is converted into absolute phase data through the near-field millimeter wave phase unwrapping technology; the multi-frequency near-field millimeter wave technology is adopted to reduce the influence of Gaussian noise, so that a better imaging result is obtained.

To provide an X-ray phase imaging apparatus and an image processing method for improving contrast and visibility of an image photographed by a phase contrast method.SOLUTION: According to an aspect of the present invention, there is provided an X-ray phase imaging apparatus comprising an X-ray source, a detector configured to detect X-rays emitted from the X-ray source to a subject, and an image processing unit configured to generate an image of the subject, the image processing unit includes a storage unit in which a plurality of noise correction images for correcting a luminance variation between pixels are stored separately for brightness and darkness, and an image generation unit that generates a luminance image of the subject by irradiating the subject with X-rays, generates a plurality of corrected images of the subject by correcting the luminance image according to the noise correction image, and generates one subject image by selecting the plurality of corrected images according to a threshold value.SELECTED DRAWING: Figure 5

The present application relates to the field of optical interferometry, and aims at the phase distortion problem in off-axis interferometric quantitative phase imaging, and provides an interferometric microscopic phase distortion elimination method based on PACUNeXt3+ network. The method comprises the following steps: 1. using Zernike polynomials and test target pictures to simulate and generate a data set; 2. establishing and training a PACUNeXt3+ neural network model; 3. inputting the interference graph I or of the sample to be measured into the trained neural network, and outputting the background interference graph I' r corresponding to the sample without sample information; 4. using the two interference graphs I or and I' r to reconstruct the sample phase distribution φ o (x, y) without phase distortion. The present application has high precision and speed, can eliminate the secondary or high-order phase distortion in interferometric quantitative phase imaging, and has great application prospect in the field of phase imaging.

The application relates to a kind of quantitative imaging methods of living cells based on digital holographic microscopic sequential displacement aberration correction, and belongs to the field of optical measurement, comprising: collecting three holograms by sequentially displacing living cells; obtaining three original phase maps by phase demodulation; obtaining total mask map; sequentially displacing phase map in reverse direction; performing difference calculation to obtain global phase system aberration difference data; obtaining local system aberration difference data by using total mask map; performing difference processing on Chebyshev polynomial to obtain local polynomial difference data by using total mask map; fitting global system aberration by calculating corresponding coefficients from difference data; subtracting global system aberration from three original phase maps to obtain phase map of living cells after aberration correction. The application realizes high-precision quantitative phase imaging of living cells while retaining high-frequency information, has excellent displacement distance robustness, does not need to be equipped with high-precision displacement mechanism, and greatly reduces the hardware cost of measurement system.

The present disclosure provides a pathology sample virtual staining apparatus and method that can easily acquire virtual staining sample images for unlabeled samples as well as decolorized samples, by including a sample image acquisition module that irradiates near-infrared light toward a placed sample to acquire a near-infrared-based phase image of the sample, and a virtual staining module that receives the near-infrared-based phase image and performs neural network computation to acquire a virtual staining image similar to an image of a stained sample in which the sample is stained.

This invention discloses a heterodyne digital holographic microscopic phase imaging scheme based on a moving grating. The scheme includes an optical imaging device and a measurement method. The optical imaging device includes a light source system, an amplification system, a heterodyne interferometry system, and an image acquisition system. A light beam emitted from the light source penetrates the object under test, carrying the object's optical phase information. This information is amplified by the amplification system and then passed through a moving grating in the heterodyne microscopy system, splitting the incident light into multiple beams of different frequencies. An aperture is used to select the 0th and +1st order beams, which interfere on the camera's detection surface to generate continuous moving interference fringes. The measurement method mainly includes: optical path adjustment, image data acquisition, image processing, and phase-height calibration. This invention achieves higher reconstruction accuracy compared to traditional single-image reconstruction schemes, and features low cost and good stability, providing a new measurement scheme and approach for digital holographic microscopy.

A quantitative phase contrast imaging system comprises a light source configured to generate light and to direct the light to a sample, wherein the light comprises nonlinearly polarized light; a first lens configured to receive light from the sample; a phase filter, wherein the first lens is configured to focus the light from the sample onto the phase filter, and the phase filter is configured to modulate multiple components of the nonlinearly polarized light simultaneously (e.g., geometric phase interferometry); a second lens configured to receive light from the phase filter; and a polarized camera, wherein the second lens is configured to collimate the light beam from the phase filter to the polarized camera and the polarized camera is configured to image the sample in response to the light from the phase filter. In absence of the second lens, the camera can be placed at the image plane.

The invention provides a single-time ultrafast multi-mode time sequence phase imaging device, and relates to the technical field of ultrafast optical imaging and computational optical imaging, and the imaging device comprises a light source system which is used for generating a linearly polarized femtosecond laser pulse; the chirp laser pulse generation system generates a chirp laser pulse based on the femtosecond laser pulse; the pulse shaping system is used for generating a time sequence multi-wavelength sub-pulse based on the chirp laser pulse; and the coherent modulation imaging system performs coherent modulation imaging based on the time sequence multi-wavelength sub-pulses, and realizes single-time ultrafast multi-modal time sequence phase imaging by using a wavelength and modulation coding combined constraint inversion algorithm. After femtosecond laser pulses are converted into chirped pulses, coaxial time sequence multi-wavelength sub-pulses with harmonious time resolution and harmonious sub-pulse number are generated by using a pulse shaping technology.

The invention discloses an SPR phase imaging system based on a four-polarization filtering array, and the system comprises an incident light path which is used for generating area array laser; the SPR module is used for receiving the area array laser and carrying out SPR sensing to obtain an area array laser modulation result related to a to-be-detected substance; and the imaging light path is used for carrying out amplification and filtering modulation on the area array laser modulation result so as to carry out imaging on a four-polarization array, and carrying out matched filtering and double-differential phase resolving on a four-polarization image so as to obtain an imaging result. According to the invention, through polarization virtual image generation and cross-channel block matching, and in combination with four-dimensional collaborative filtering, the noise suppression efficiency is improved; and through double differential phase resolving, the dynamic range is expanded to 0.06 RIU, and the resolution ratio is superior to that of the RIU. The invention solves the problem of mutual restriction of dynamic range and resolution in the traditional SPR technology, and is suitable for high-sensitivity biomolecule interaction detection.

Mesoscopic imaging systems and methods comprise or utilize a light source configured to generate an illumination light; an optical system configured to direct the illumination light toward a sample; an objective lens having a numerical aperture (NA) of 0.2 to 0.6, the objective lens being configured to receive a response light emitted by the sample in response to the illumination light; a filter wheel comprising a plurality of emission filters configured to filter the response light to generate a filtered light; a tube lens configured to provide an optical magnification to the filtered light; and an image sensor having 40 megapixels or more and a pixel size of less than or equal to 4 μm, the image sensor being configured to receive the filtered light and generate image data based on the received filtered light.

The present invention provides an acoustic field detection system, method, electronic device, and medium based on dual-detector phase imaging, comprising: a parallel light field emission module, which is used to generate a pulse parallel light field to illuminate an acoustic field medium, the pulse parallel light field is subjected to wavefront modulation by the acoustic field medium, amplified and imaged by an imaging module, and the pulse parallel light field is beam-splittered into a transmitted wavefront and a reflected wavefront, and a first light field intensity distribution corresponding to the transmitted wavefront is recorded by a first light field detector, and a second light field intensity distribution corresponding to the reflected wavefront is recorded by a second light field detector; an ultrasonic transducer module, which is used to generate a high-frequency acoustic field to be measured; and a control and calculation module, which is used to control the synchronization of the parallel light field emission module and the first light field detector and the second light field detector, and store the first light field intensity distribution and the second light field intensity distribution to calculate the complex amplitude distribution of the high-frequency acoustic field to be measured.

The application discloses a kind of single-pixel phase imaging method, system, device and storage medium, imaging system includes light source, pre-processing module, first spatial modulator, second spatial modulator, lens, detector, data acquisition card and processor, light emitted by light source collimates and attenuates after pre-processing module, in turn after first spatial modulator, measured object, second spatial modulator and lens, to detector;Imaging method includes: obtaining the first hologram and second hologram of phase difference preset phase shift, according to first hologram, second hologram and pre-design formula, the hologram of measured object is calculated, according to the hologram of measured object and preset algorithm, the reconstructed image of measured object is calculated.The efficiency of the embodiment of the application improves phase shift holographic imaging, and can be widely applied to imaging technical field.

The application relates to the technical field of mine evaluation, in particular to a mine available resource evaluation method and system.The method comprises the following steps: obtaining mine resource geological exploration data; performing data preprocessing on the mine resource geological exploration data to generate standard mine resource geological exploration data; performing three-dimensional geological modeling based on the standard mine resource geological exploration data to generate mine resource reserve distribution data; obtaining a surface deformation monitoring image through a synthetic aperture radar; performing time sequence slicing on the surface deformation monitoring image to generate surface deformation slice data; and performing stress change and microseismic phase imaging on the surface deformation slice data, so that time sequence stress data and microseismic phase data are obtained.The application improves the accuracy, dynamic nature and geological risk early warning capability of mine resource evaluation through multi-source dynamic data fusion and three-dimensional modeling, and improves the precision of mine available resource evaluation.

The application discloses an imaging sensor based on a full-Stokes polarization superlens, and relates to the field of optical sensing.The imaging sensor comprises a sensing excitation light source, an adjustable attenuator, a polarizer, a coupling prism, a sensing chip, a first objective lens, a full-Stokes polarization superlens, a second objective lens, an imaging lens and a CCD imaging camera; the sensing excitation light source emits monochromatic light as system incident light, which sequentially passes through the adjustable attenuator and the polarizer, and is incident onto the surface of the sensing chip to generate surface plasmon resonance after passing through the coupling prism; reflected light is converged onto the polarization superlens by the first objective lens, and then converged onto the second objective lens; subsequently, the imaging lens is used for imaging to the CCD camera; the property change of a to-be-measured sample leads to surface plasmon resonance of the sensing chip, which causes the analysis information of the full-Stokes polarization superlens to change, and further causes the image obtained by the CCD imaging camera to change.The application can perform single-shot phase imaging on a refractive index sample.

The utility model provides microscopic imaging equipment. The microscopic imaging equipment comprises a base, a supporting piece, a light source assembly, an object carrying platform, an objective lens assembly, a fluorescence imaging module and a quantitative phase imaging module, the supporting piece is arranged on the base, the light source assembly is arranged at the top of the supporting piece, the light source assembly is connected with a first light source, and the light source assembly comprises a second light source; the object carrying platform and the objective lens assembly are both arranged on the supporting piece, the object carrying platform is used for carrying a to-be-observed sample, and the objective lens assembly is located below the object carrying platform; the fluorescence imaging module is arranged on the base and comprises a fluorescence light source and a first camera; the quantitative phase and the fluorescence imaging module are arranged adjacently. The microscopic imaging equipment provided by the utility model can provide quantitative phase imaging, fluorescence imaging and bright field imaging, the imaging cost of a sample is saved, the use convenience is improved, the modules on the microscopic imaging equipment are compactly connected, and the size of the microscopic imaging equipment is reduced.