The invention discloses an organic light-emitting display device, which comprises a lower substrate, a packaging layer, at least one light extraction layer, an electrode layer, a light-emitting layer and a functional layer, wherein the electrode layer, the light-emitting layer and the functional layer are arranged between the lower substrate and the packaging layer, and a micropore structure is formed in the light extraction layer. The invention further discloses a manufacturing method of the organic light-emitting display device. The organic light-emitting display device is provided with the light extraction layer with the micropore structure, and enables light to be scattered repeatedly by micropores when getting into the light extraction layer through reasonably setting the position of the light extraction layer, thereby reducing internal reflection at the light extraction layer on the whole, and enabling more light to be extracted and emitted from the light-emitting device. Therefore, the light-emitting efficiency of the device can be substantially improved. In addition, the organic light-emitting display device can be manufactured in a large scale, is low in cost and has important practical application values.