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Edible composition as well as preparation method and application thereof

The technology of a composition and medicine is applied in the field of edible composition and its preparation, which can solve the problem of in-depth adjustment of animal intestinal flora, and achieve the effects of enhancing immunity, increasing the concentration of butyric acid, and preventing or treating obesity.

Inactive Publication Date: 2015-03-18
BGI SHENZHEN CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, research on the regulation of gut microbiota in animals remains to be done

Method used

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  • Edible composition as well as preparation method and application thereof
  • Edible composition as well as preparation method and application thereof
  • Edible composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Preparation of inulin capsules

[0031] Weigh 10 parts by weight of inulin, process and pulverize it with ultra-fine crushing equipment to obtain fine inulin powder with a particle size of 100 microns, homogenize it into a mixed fine powder, and then place the content materials in a soft capsule pilling machine , fill and press into soft capsules according to the existing soft capsule production technology.

[0032] 2. Preparation of live Clostridium butyricum capsules

[0033] Weigh 10 parts by weight of Clostridium butyricum (ATCC product number 19398), process and pulverize it with ultra-fine grinding equipment to obtain Clostridium butyricum fine powder with a particle size of 100 microns, and homogenize it into a mixed fine powder, and then the content materials are placed in a soft capsule pellet machine, filled and compressed into soft capsules according to the existing soft capsule production technology.

[0034] 3. Preparation of Live Clostridium Butyricum...

Embodiment 2

[0069] Example 2: Function experiment of regulating human intestinal flora

[0070] 1. Grouping of feeding experiments

[0071] According to the Ministry of Public Health's "Health Food Inspection and Evaluation Technical Specifications (2003)" human body test and evaluation method for regulating intestinal flora function, each product obtained in Example 1 is evaluated, as follows:

[0072] The following is the grouping of the eating experiment:

[0073] Table 1 Grouping table of eating experiment

[0074]

[0075]

[0076]

[0077] 2. Human food test method

[0078] The subjects were randomly divided into 19 groups, with 10 people in each group. Before the subjects tried to eat, the feces of the subjects were collected aseptically, and the intestinal flora was tested by 16S rDNA sequencing as a reference for the background level.

[0079] According to the grouping situation in Table 1, group 1 took live Clostridium butyricum capsules, group 2 took live Clostridiu...

Embodiment 3

[0089] Embodiment 3: hypoglycemic animal experiment

[0090] According to the animal experiment evaluation method of auxiliary hypoglycemic function of "Health Food Inspection and Evaluation Technical Specifications (2003)" of the Ministry of Health, the product obtained in Example 1 is evaluated, as follows:

[0091] 1. Test method: 190 male SD rats were taken, and a low-dose streptozotocin-induced diabetic rat model was prepared according to the standard method. After three days, the rats were randomly divided into 19 groups according to the blood sugar level, with 10 rats in each group. Each group was administered by intragastric administration for 8 consecutive days, once a day, and blood was collected two hours after the last administration to measure the blood sugar level.

[0092] 2. Test object: The tested SD rats were randomly divided into 19 groups, 10 in each group. The original diet control and activities of the tested SD rats remained unchanged. According to the g...

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Abstract

The invention discloses an edible composition as well as a preparation method and application thereof. The edible composition comprises inulin and butyric acid producing bacteria in a weight ratio of 1 to 1. Inulin and butyric acid producing bacteria in the edible composition have synergistic effects and can conduce to obviously increasing the concentrations of butyric acids in intestinal tracts of animals and the quantities of probiotics, such as lactobacillus and bifidobacterium, and inhibiting growth of harmful bacteria, thus effectively regulating intestinal floras of animals and then enhancing the immunities based on the effects of the intestinal floras and preventing or treating the diseases, such as obesity, diabetes mellitus, hypertension, hyperlipidemia or tumors.

Description

technical field [0001] The present invention relates to an edible composition and its preparation method and application, in particular, to an edible composition and its preparation method and in regulating animal intestinal flora and preventing or treating diabetes, hyperlipidemia, hypertension, obesity or tumor the use of. More specifically, the present invention relates to edible compositions, methods of preparing edible compositions, uses of edible compositions in the preparation of medicaments, medicaments and functional foods. Background technique [0002] The human gastrointestinal tract inhabits about 10 4 An order of magnitude of normal flora, the total amount of which is similar to that of the liver. Gut microbes contain a wide variety of enzyme systems, which can participate in a series of physiological processes such as host energy, material and genetic information transfer. Many studies have proved that intestinal microorganisms can form a biological barrier ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/741A61K35/742A23L1/09A61P3/04A61P3/10A61P9/12A61P3/06A61P35/00A61P37/04A61P1/00A61K31/733A23L33/125A23L33/135
CPCA23V2002/00A61K9/48A61K31/733A61K35/741A61K35/742A61K2300/00A23V2200/30A23V2200/308A23V2200/324A23V2200/326A23V2200/328A23V2200/332A23V2250/5062Y02A50/30
Inventor 张海峰过敏朱江阳丁淑娟朱端清张耕耘金桃邱学兵
Owner BGI SHENZHEN CO LTD
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