Traditional Chinese medicine composition for protecting liver and soothing nerves and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for protecting the liver and soothing the nerves and a preparation method thereof. The traditional Chinese medicine composition comprises hovenia dulcis thunb decoction pieces, vinegar-processed kadsura longepedunculata decoction pieces, radix puerariae decoction pieces, parched white peony root decoction pieces, salvia miltiorrhiza decoction pieces, vinegar-processed bupleurum chinense decoction pieces, poria cocos decoction pieces and honey-fried licorice root decoction pieces. Aiming at the characteristics of effective components in hovenia dulcis thunb, kadsura longepedunculata processed with vinegar, the root of kudzu vine, parched white peony root, the root of red-rooted salvia, bupleurum chinense processed with vinegar, poria cocos and honey-fried licorice root and the traditional Chinese medicine theory, the traditional Chinese medicine composition is prepared by adopting the steps of water extraction, concentration and drying according to the traditional Chinese medicine process. The dry granulation maximally retains the effective components, increases the concentration of the effective components, improves the biological activity of the effective components and ensures the efficacy of the product, the dry granulation is adopted in the granulation process, wetting and heating are avoided, the effective components are not lost and are all retained, dextrin is adopted as a filler and an adhesive, and sugar components are not contained. The beverage can be used by normal people and people with abnormal glucose metabolism.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine preparation technology, and in particular to a liver-protecting and calming traditional Chinese medicine composition and its preparation method. Background Technology

[0002] The liver is the name of a human organ, one of the five major organs. It is an organ in vertebrates that is mainly responsible for metabolism. It plays a vital role in the body, including deoxidation, glycogen storage, and the synthesis of secretory proteins. The liver also produces bile for the digestive system. Most liver diseases present with jaundice, which is caused by the liver's inability to excrete bilirubin, leading to its accumulation in the body.

[0003] This shows the importance of the liver to the human body. If the liver has problems, symptoms such as dizziness, tinnitus, palpitations, irritability, insomnia, and forgetfulness may occur, such as liver qi stagnation, liver fire disturbing the heart, or heart yin deficiency. Summary of the Invention

[0004] The main objective of this invention is to provide a traditional Chinese medicine composition for protecting the liver and calming the mind, and its preparation method, which can effectively solve the problems in the background art.

[0005] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0006] A traditional Chinese medicine composition for protecting the liver and calming the mind, comprising slices of Hovenia dulcis, Schisandra chinensis (processed with vinegar), Pueraria lobata (processed), stir-fried Paeonia lactiflora (processed), Salvia miltiorrhiza (processed), Bupleurum chinense (processed with vinegar), Poria cocos (processed), and Glycyrrhiza uralensis (processed). One portion of the liver-protecting and calming traditional Chinese medicine composition contains 270g of Hovenia dulcis, 150g of Schisandra chinensis (processed with vinegar), 300g of Pueraria lobata (processed), 270g of stir-fried Paeonia lactiflora (processed), 360g of Salvia miltiorrhiza (processed), 240g of Bupleurum chinense (processed with vinegar), 300g of Poria cocos (processed), and 180g of Glycyrrhiza uralensis (processed).

[0007] A method for preparing a traditional Chinese medicine composition for protecting the liver and calming the nerves, comprising the following preparation steps:

[0008] S1: Pre-processing of raw and auxiliary materials: Prepare sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root according to the required weight. Select and inspect the sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root in sequence. After passing the inspection, set them aside for later use.

[0009] S2: Extraction and Concentration Process: The qualified Hovenia dulcis slices, vinegar-processed Schisandra chinensis slices, Pueraria lobata slices, stir-fried Paeonia lactiflora slices, Salvia miltiorrhiza slices, vinegar-processed Bupleurum chinense slices, Poria cocos slices, and prepared Glycyrrhiza uralensis slices are placed in an extraction tank. Ten times the amount of water is added for a single extraction at 80℃ for 2 hours. The extract is then filtered and set aside for later use. Add eight times the amount of water to the following ingredients for a second extraction: Hovenia dulcis slices, Schisandra chinensis slices (processed with vinegar), Pueraria lobata slices, stir-fried Paeonia lactiflora slices, Salvia miltiorrhiza slices, Bupleurum chinense slices (processed with vinegar), Poria cocos slices, and Glycyrrhiza uralensis slices (processed with roasted). The second extraction is performed at 100℃ for 2.5 hours. The second extract is then filtered and combined with the first extract. The mixture is then concentrated under reduced pressure at 0.08 MPa and 70℃ until it reaches a thin paste with a relative density of 1.05-1.10 (measured at 60℃). This paste is then set aside for later use.

[0010] S3: Drying treatment: The thin paste is dried by spraying until its moisture content is 5%, and then the extract powder is obtained and set aside for later use.

[0011] S4: Granulation process: Add maltodextrin to the obtained extract powder, mix them evenly, and then use dry granulation to prepare 20-40 mesh particles to complete the finished granules.

[0012] S5 Packaging: The finished granules are packaged in aluminum foil bags, 10g per bag;

[0013] S6: Outer Packaging: The packaged finished granules are then packaged in the production area to obtain the finished traditional Chinese medicine composition.

[0014] Preferably, in step S1, when selecting slices of Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata (kudzu root), stir-fried Paeonia lactiflora (fried), Salvia miltiorrhiza (danshen), Bupleurum chinense (vinegar-processed), Poria cocos (poria cocos), and Glycyrrhiza uralensis (roasted), they are observed and tested for insect infestation and mold, and their moisture content is tested, which should be 7%-13%.

[0015] Preferably, in step S1, when selecting slices of Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata (kudzu root), stir-fried Paeonia lactiflora (fried), Salvia miltiorrhiza (danshen), Bupleurum chinense (vinegar-processed), Poria cocos (poria cocos), and Glycyrrhiza uralensis (roasted), it is necessary to inspect their processing techniques and observe their color and odor. If the color is too dark or the odor is sour, foul, or bitter, they should not be selected.

[0016] Preferably, in step S1, when selecting slices of Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata (kudzu root), stir-fried Paeonia lactiflora (fried), Salvia miltiorrhiza (danshen), Bupleurum chinense (vinegar-processed), Poria cocos (poria cocos), and Glycyrrhiza uralensis (roasted), the collected slices must be from the current year and season, and the slices must be fresh in color and have their inherent color, aroma, and flavor.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] This invention targets the characteristics of the effective components in *Hovenia dulcis*, *Schisandra chinensis* (processed with vinegar), *Pueraria lobata*, stir-fried *Paeonia lactiflora*, *Salvia miltiorrhiza*, *Bupleurum chinense* (processed with vinegar), *Poria cocos*, and *Glycyrrhiza uralensis* (processed with roasted licorice), and follows traditional Chinese medicine principles. It employs water extraction, concentration, and drying, followed by dry granulation to maximize the retention of effective components, increasing their concentration and bioactivity, thus ensuring product efficacy. The dry granulation process avoids wetting and heating, preserving all effective components without loss. Most granules on the market use sucrose as a filler, making them inconvenient for people with abnormal glucose metabolism. This product uses dextrin as a filler and binder, containing no sugars, making it suitable for both healthy individuals and those with abnormal glucose metabolism. This formula is derived from ancient classic prescriptions with modifications and has been clinically proven in hospitals for many years, demonstrating its efficacy. The product's safety has been verified through animal and clinical trials, showing it to be safe and effective with few and mild adverse reactions. Detailed Implementation

[0019] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0020] This invention relates to a traditional Chinese medicine composition for protecting the liver and calming the mind, comprising slices of Hovenia dulcis, slices of Schisandra chinensis (processed with vinegar), slices of Pueraria lobata, slices of Paeonia lactiflora (processed with stir-fried), slices of Salvia miltiorrhiza, slices of Bupleurum chinense (processed with vinegar), slices of Poria cocos, and slices of Glycyrrhiza uralensis (processed with roasted). One portion of the traditional Chinese medicine composition for protecting the liver and calming the mind contains 270g of Hovenia dulcis, 150g of Schisandra chinensis (processed with vinegar), 300g of Pueraria lobata, 270g of Paeonia lactiflora (processed with stir-fried), 360g of Salvia miltiorrhiza, 240g of Bupleurum chinense (processed with vinegar), 300g of Poria cocos, and 180g of Glycyrrhiza uralensis (processed with roasted).

[0021] A method for preparing a traditional Chinese medicine composition for protecting the liver and calming the nerves includes the following preparation steps:

[0022] S1: Pre-processing of raw and auxiliary materials: Prepare sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root according to the required weight. Select and inspect the sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root in sequence. After passing the inspection, set them aside for later use.

[0023] When selecting sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root, they should be inspected for insect infestation and mold, and their moisture content should be tested. The moisture content should be 7%-13%. When selecting medicinal herbs, it is necessary to inspect their processing techniques and observe their color and aroma. If the color is too dark or the aroma is sour, foul, or bitter, they should not be selected. When selecting herbs such as Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata, stir-fried Paeonia lactiflora, Salvia miltiorrhiza, Bupleurum chinense (vinegar-processed), Poria cocos, and Glycyrrhiza uralensis (roasted), the collected herbs must be from the current year and season, and the herbs must be fresh in color and have their inherent color, aroma, and odor.

[0024] S2: Extraction and Concentration Process: The qualified Hovenia dulcis slices, vinegar-processed Schisandra chinensis slices, Pueraria lobata slices, stir-fried Paeonia lactiflora slices, Salvia miltiorrhiza slices, vinegar-processed Bupleurum chinense slices, Poria cocos slices, and prepared Glycyrrhiza uralensis slices are placed in an extraction tank. Ten times the amount of water is added for a single extraction at 80℃ for 2 hours. The extract is then filtered and set aside for later use. Add eight times the amount of water to the following ingredients for a second extraction: Hovenia dulcis slices, Schisandra chinensis slices (processed with vinegar), Pueraria lobata slices, stir-fried Paeonia lactiflora slices, Salvia miltiorrhiza slices, Bupleurum chinense slices (processed with vinegar), Poria cocos slices, and Glycyrrhiza uralensis slices (processed with roasted). The second extraction is performed at 100℃ for 2.5 hours. The second extract is then filtered and combined with the first extract. The mixture is then concentrated under reduced pressure at 0.08 MPa and 70℃ until it reaches a thin paste with a relative density of 1.05-1.10 (measured at 60℃). This paste is then set aside for later use.

[0025] S3: Drying treatment: The thin paste is dried by spraying until its moisture content is 5%, and then the extract powder is obtained and set aside for later use.

[0026] S4: Granulation process: Add maltodextrin to the obtained extract powder, mix them evenly, and then use dry granulation to prepare 20-40 mesh particles to complete the finished granules.

[0027] S5 Packaging: The finished granules are packaged in aluminum foil bags, 10g per bag;

[0028] S6: Outer Packaging: The packaged finished granules are then packaged in the production area to obtain the finished traditional Chinese medicine composition. Specific Implementation Example 1:

[0030] In this invention, the product is the processed form of the medicinal material *Hovenia dulcis*. It is sweet in taste and neutral in nature. It enters the heart and spleen meridians and has the functions of quenching thirst and relieving irritability, clearing damp heat, and detoxifying alcohol. It is used for symptoms such as alcohol poisoning, thirst, vomiting, and difficulty in urination and defecation.

[0031] Vinegar-processed Schisandra chinensis: This product is the dried, mature fruit of Schisandra chinensis, a plant of the Magnoliaceae family. The fruit is harvested in autumn when it is ripe, dried in the sun, and the fruit stalks and impurities are removed. It has a sour and sweet taste and is warm in nature. It enters the lung, heart, and kidney meridians and has the functions of astringing and consolidating, replenishing qi and promoting body fluids, tonifying the kidneys and calming the mind. It is used for chronic cough and wheezing, nocturnal emission and spermatorrhea, enuresis and frequent urination, chronic diarrhea, spontaneous sweating and night sweats, thirst due to fluid depletion, internal heat and thirst, palpitations and insomnia.

[0032] Kudzu root: This product is the dried root of the legume Pueraria lobata, commonly known as wild kudzu. It is harvested in autumn and winter and cut into thick slices or small pieces while fresh. After drying, it is sweet and pungent in taste and cool in nature. It enters the spleen, stomach and lung meridians and has the functions of relieving muscle tension and reducing fever, promoting body fluid and quenching thirst, promoting rash eruption, raising yang and stopping diarrhea, clearing the meridians and activating collaterals, and detoxifying alcohol. It is used for exogenous fever and headache, stiff neck and back pain, thirst, diabetes, measles that fail to erupt, dysentery, diarrhea, dizziness and headache, hemiplegia due to stroke, chest pain and heart pain, and damage to the middle jiao due to alcohol poisoning.

[0033] Fried white peony root: This product is the dried root of the peony plant of the Ranunculaceae family. It is harvested in summer and autumn, washed, and the head, tail and fine roots are removed. It is boiled in boiling water and the outer skin is removed or the skin is removed and then boiled. It is dried in the sun. It tastes bitter and sour and is slightly cold in nature. It enters the liver and spleen meridians. It nourishes blood and regulates menstruation, astringes yin and stops sweating, softens the liver and relieves pain, and calms liver yang. It is used for blood deficiency and chlorosis, irregular menstruation, spontaneous sweating, night sweats, hypochondriac pain, abdominal pain, limb spasms, headache and dizziness.

[0034] Danshen: This product is the dried root and rhizome of the plant Danshen, belonging to the Lamiaceae family. It is harvested in spring and autumn, cleaned of mud and sand, dried, bitter in taste, and slightly cold in nature. It enters the heart and liver meridians and has the functions of promoting blood circulation and removing blood stasis, regulating menstruation and relieving pain, clearing the heart and relieving irritability, cooling blood and eliminating carbuncles. It is used for chest pain, abdominal pain, abdominal masses, heat arthralgia, insomnia, irregular menstruation, dysmenorrhea, amenorrhea, sores and swelling.

[0035] Vinegar-processed Bupleurum: This product is the dried root of Bupleurum chinense or Bupleurum stenoptera, plants of the Apiaceae family. According to different characteristics, it is commonly known as "Northern Bupleurum" and "Southern Bupleurum". It is harvested in spring and autumn, and the stems, leaves and mud are removed. It is dried and has a pungent and bitter taste, and is slightly cold in nature. It enters the liver, gallbladder and lung meridians. It disperses and reduces fever, soothes the liver and relieves depression, and raises yang qi. It is used for colds with fever, alternating chills and fever, chest and rib pain, irregular menstruation, uterine prolapse and rectal prolapse.

[0036] Poria cocos: This product is the dried sclerotium of the fungus Poria cocos, which is harvested from July to September. After being dug up, the mud and sand are removed, and the fungus is piled up to "sweat". Then it is spread out to dry until the surface is dry, and then "sweat" again. This process is repeated several times until wrinkles appear and most of the internal moisture is lost. Finally, it is dried in the shade and called "Poria cocos pieces". Alternatively, fresh Poria cocos can be cut into different parts and dried in the shade, which are called "Poria cocos chunks" and "Poria cocos slices" respectively. It is sweet and bland in taste and neutral in nature. It enters the heart, lung, spleen and kidney meridians. It has the functions of promoting diuresis and removing dampness, strengthening the spleen and calming the mind. It is used for edema with scanty urine, phlegm retention with dizziness and palpitations, spleen deficiency with poor appetite, loose stools and diarrhea, restlessness, palpitations and insomnia.

[0037] Prepared licorice root: This product is the dried root and rhizome of licorice, licorice inflata, or licorice glabra, all belonging to the legume family. It is harvested in spring and autumn, the fibrous roots are removed, and it is sun-dried. It has a sweet taste and neutral properties; it enters the heart, lung, spleen, and stomach meridians. It tonifies the spleen and replenishes qi, clears heat and detoxifies, eliminates phlegm and stops cough, relieves spasms and pain, and harmonizes other medicines. It is used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough with excessive phlegm, abdominal and limb spasms and pain, carbuncles and boils, and to alleviate the toxicity and harshness of other medicines. Specific Implementation Example 2:

[0039] Toxicological tests:

[0040] 1. Acute toxicity test of liver-protecting and calming granules:

[0041] When ICR mice were administered the hepatoprotective and calming granules suspension at the maximum concentration of 50% by gavage, the LD50 was not determined. Therefore, a maximum dose test was conducted, and the maximum dose was found to be 60g of powder / kg, which is equivalent to 280g of crude drug / kg, or 800 times the human dose. Therefore, the hepatoprotective and calming granules administered to mice by gavage had no acute toxic effects.

[0042] II. Long-term toxicity test in rats:

[0043] The Liver-Protecting and Tranquilizing Granules have the functions of soothing the liver and relieving depression, calming the liver and nourishing the heart. They are used for dizziness, tinnitus, palpitations, irritability, insomnia, and forgetfulness caused by liver qi stagnation, liver fire disturbing the heart, or heart yin deficiency. Rats were administered the granules by gavage at doses of 10g / kg, 5g / kg, and 2.5g / kg (equivalent to 20, 10, and 5 times the daily adult dose, respectively) for 13 weeks. Some animals were sacrificed for pathological, toxicological, hematological, blood biochemical, and urinary examinations. After 4 weeks of recovery following drug withdrawal, the above examinations were repeated. The results showed that under the experimental conditions, the Liver-Protecting and Tranquilizing Granules had no significant effect on the general condition, weight, diet and water intake, hematology, blood biochemistry, systemic anatomy, organ coefficients, histopathology, and urine of rats. No long-term toxic reactions were found, and there were no delayed toxic reactions during the recovery period. This suggests that the no-toxicity dose for rats is 10g of powder / kg / day.

[0044] A long-term toxicity test of the liver-protecting and calming granules in rats was conducted for 6 months, as required by the clinical trial approval. Rats were administered the granules by gavage at doses of 10 g / kg, 5 g / kg, and 2.5 g / kg (equivalent to 20, 10, and 5 times the adult daily dose, respectively) for 6 months. Some animals were sacrificed for pathological, toxicological, hematological, blood biochemical, and urinary examinations. After a one-month recovery period following drug withdrawal, the above examinations were repeated for some animals. The results showed that under the experimental conditions, the liver-protecting and calming granules had no significant effect on the general condition, weight, diet, water intake, hematological, blood biochemical, systemic anatomy, organ coefficients, histopathology, or urine of the rats. No long-term toxic reactions were observed, and no delayed toxic reactions were observed during the recovery period. This suggests that the no-toxicity dose for rats is 10 g powder / kg / day.

[0045] In summary, toxicological studies have shown that the traditional Chinese medicine composition prepared in this invention has excellent safety when used clinically. Specific Implementation Example 3:

[0047] The performance of the traditional Chinese medicine composition prepared according to this invention was compared with that of two commonly available hepatoprotective and sedative traditional Chinese medicine compositions. This invention is an example, and the two commercially available hepatoprotective and sedative traditional Chinese medicine compositions are designated as Comparative Examples 1-2. The comparison table is as follows:

[0048] Number of examples Significant efficiency Example 100 91 91％ Comparative Example 1 100 60 60％ Comparative Example 2 100 72 72％

[0049] Therefore, it can be seen that the liver-protecting and calming traditional Chinese medicine composition prepared by this invention has a high efficacy rate.

[0050] This invention targets the characteristics of the effective components in *Hovenia dulcis*, *Schisandra chinensis* (processed with vinegar), *Pueraria lobata*, stir-fried *Paeonia lactiflora*, *Salvia miltiorrhiza*, *Bupleurum chinense* (processed with vinegar), *Poria cocos*, and *Glycyrrhiza uralensis* (processed with roasted licorice), and follows traditional Chinese medicine principles. It employs water extraction, concentration, and drying, followed by dry granulation to maximize the retention of effective components, increasing their concentration and bioactivity, thus ensuring product efficacy. The dry granulation process avoids wetting and heating, preserving all effective components without loss. Most granules on the market use sucrose as a filler, making them inconvenient for people with abnormal glucose metabolism. This product uses dextrin as a filler and binder, containing no sugars, making it suitable for both healthy individuals and those with abnormal glucose metabolism. This formula is derived from ancient classic prescriptions with modifications and has been clinically proven in hospitals for many years, demonstrating its efficacy. The product's safety has been verified through animal and clinical trials, showing it to be safe and effective with few and mild adverse reactions.

[0051] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A traditional Chinese medicine composition for protecting the liver and calming the nerves, characterized in that: The formula includes sliced ​​Hovenia dulcis, sliced ​​Schisandra chinensis (vinegar-processed), sliced ​​Pueraria lobata, sliced ​​stir-fried Paeonia lactiflora, sliced ​​Salvia miltiorrhiza, sliced ​​Bupleurum chinense (vinegar-processed), sliced ​​Poria cocos, and sliced ​​Glycyrrhiza uralensis (processed). One portion of the liver-protecting and calming traditional Chinese medicine composition contains 270g of sliced ​​Hovenia dulcis, 150g of sliced ​​Schisandra chinensis (vinegar-processed), 300g of sliced ​​Pueraria lobata, 270g of sliced ​​stir-fried Paeonia lactiflora, 360g of sliced ​​Salvia miltiorrhiza, 240g of sliced ​​Bupleurum chinense (vinegar-processed), 300g of sliced ​​Poria cocos, and 180g of sliced ​​Glycyrrhiza uralensis (processed).

2. The method for preparing a liver-protecting and calming traditional Chinese medicine composition according to claim 1, characterized in that: The preparation steps include the following: S1: Pre-processing of raw and auxiliary materials: Prepare sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root according to the required weight. Select and inspect the sliced ​​jujube fruit, vinegar-processed schisandra fruit, kudzu root, stir-fried white peony root, salvia miltiorrhiza, vinegar-processed bupleurum root, poria cocos, and prepared licorice root in sequence. After passing the inspection, set them aside for later use. S2: Extraction and Concentration Process: The qualified Hovenia dulcis slices, vinegar-processed Schisandra chinensis slices, Pueraria lobata slices, stir-fried Paeonia lactiflora slices, Salvia miltiorrhiza slices, vinegar-processed Bupleurum chinense slices, Poria cocos slices, and prepared Glycyrrhiza uralensis slices are placed in an extraction tank. Ten times the amount of water is added for a single extraction at 80℃ for 2 hours. The extract is then filtered and set aside for later use. Add eight times the amount of water to the following ingredients for a second extraction: Hovenia dulcis slices, Schisandra chinensis slices (processed with vinegar), Pueraria lobata slices, stir-fried Paeonia lactiflora slices, Salvia miltiorrhiza slices, Bupleurum chinense slices (processed with vinegar), Poria cocos slices, and Glycyrrhiza uralensis slices (processed with roasted). The second extraction is performed at 100℃ for 2.5 hours. The second extract is then filtered and combined with the first extract. The mixture is then concentrated under reduced pressure at 0.08 MPa and 70℃ until it reaches a thin paste with a relative density of 1.05-1.10 (measured at 60℃). This paste is then set aside for later use. S3: Drying treatment: The thin paste is dried by spraying until its moisture content is 5%, and then the extract powder is obtained and set aside for later use. S4: Granulation process: Add maltodextrin to the obtained extract powder, mix them evenly, and then use dry granulation to prepare 20-40 mesh particles to complete the finished granules. S5 Packaging: The finished granules are packaged in aluminum foil bags, 10g per bag; S6: Outer Packaging: The packaged finished granules are then packaged in the production area to obtain the finished traditional Chinese medicine composition.

3. The method for preparing a liver-protecting and calming traditional Chinese medicine composition according to claim 2, characterized in that: In step S1, when selecting slices of Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata (kudzu root), stir-fried Paeonia lactiflora (fried), Salvia miltiorrhiza (danshen), Bupleurum chinense (vinegar-processed), Poria cocos (poria cocos), and Glycyrrhiza uralensis (roasted), they are observed and tested for insect infestation and mold, and their moisture content is tested, which should be 7%-13%.

4. The method for preparing a liver-protecting and calming traditional Chinese medicine composition according to claim 2, characterized in that: In step S1, when selecting slices of Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata (kudzu root), stir-fried Paeonia lactiflora (fried), Salvia miltiorrhiza (danshen), Bupleurum chinense (vinegar-processed), Poria cocos (poria cocos), and Glycyrrhiza uralensis (roasted), it is necessary to inspect their processing techniques and observe their color and odor. If the color is too dark or the odor is sour, foul, or bitter, they should not be selected.

5. The method for preparing a liver-protecting and calming traditional Chinese medicine composition according to claim 2, characterized in that: In step S1, when selecting slices of Hovenia dulcis, Schisandra chinensis (vinegar-processed), Pueraria lobata (kudzu root), stir-fried Paeonia lactiflora (fried), Salvia miltiorrhiza (danshen), Bupleurum chinense (vinegar-processed), Poria cocos (poria cocos), and Glycyrrhiza uralensis (roasted), the collected slices must be from the current year and season, and the slices must be fresh in color and have their inherent color, aroma, and flavor.