55 results about "Physiological Phenomenon" patented technology

Passive Physiological monitoring apparatus and method have a sensor for sensing physiological phenomenon. A converter converts sensed data into electrical signals and a computer receives and computes the signals, and outputs computed data for real-time interactive display. The sensor is a piezoelectric film of polyvinylidene fluoride. A band-pass filter filters out noise and isolates the signals to reflect data from the body. A pre-amplifier amplifies signals. Signals detected include mechanical, thermal and acoustic signatures reflecting cardiac output, cardiac function, internal bleeding, respiratory, pulse, apnea, and temperature. A pad may incorporate the PVDF film and may be fluid-filled. The film converts mechanical energy into analog voltage signals. Analog signals are fed through the band-pass filter and the amplifier. A converter converts the analog signals to digital signals. A Fourier transform routine is used to transform into the frequency domain. A microcomputer is used for recording, analyzing and displaying data for on-line assessment and for providing realtime response. A radio-frequency filter may be connected to a cable and the film for transferring signals from the film through the cable. The sensor may be an array provided in a MEDEVAC litter or other device for measuring acoustic and hydraulic signals from the body of a patient for field monitoring, hospital monitoring, transport monitoring, home, remote monitoring.

Passive physiological monitoring apparatus and method has a sensor for sensing physiological phenomenon. A converter converts sensed data into electrical signals and a computer receives and computes the signals and outputs computed data for real-time interactive display. The sensor is a piezoelectric film of polyvinylidene fluoride. A band-pass filter filters out noise and isolates the signals to reflect data from the body. A pre-amplifier amplifies signals. Signals detected include mechanical, thermal and acoustic signatures reflecting cardiac output, cardiac function, internal bleeding, respiratory, pulse, apnea, and temperature. A pad may incorporate the PVDF film and may be fluid-filled. The film converts mechanical energy into analog voltage signals. Analog signals are fed through the band-pass filter and the amplifier. A converter converts the analog signals to digital signals. A Fourier transform routine is used to transform into the frequency domain. A microcomputer is used for recording, analyzing and displaying data for on-line assessment and for providing realtime response. A radio-frequency filter may be connected to a cable and the film for transferring signals from the film through the cable. The sensor may be an array provided in a MEDEVAC litter or other device for measuring acoustic and hydraulic signals from the body of a patient for field monitoring, hospital monitoring, transport monitoring, home, remote monitoring.

A mechanical vibration sensor adapted to be brought into contact with an object for sensing mechanical vibrations in the object, includes a body of a soft elastomeric material having high transmissivity and low attenuation properties with respect to a preselected type of energy waves; and a pair of transducers mounted, by mounting members having high attenuation properties with respect to the energy waves, in spaced relationship to each other to define a transmission channel between the transducers. Such sensor is particularly useful in a method and apparatus for controlling snoring by a person, by utilizing a stimulus device effective, when sensing snoring, to immediately produce a response in the person tending to interrupt the person's snoring.

A monitoring device receives a measurement signal obtained by a pressure sensor in an extracorporeal fluid system, such as an extracorporeal blood circuit for a dialysis machine which is in contact with a vascular system of a subject via a fluid connection. The monitoring device processes the measurement signal to identify pressure data that represents pulses originating from a first physiological phenomenon in the subject, excluding the heart of the subject. The first physiological phenomenon may be any of reflexes, voluntary muscle contractions, non-voluntary muscle contractions, a breathing system of the subject, an autonomous system of the subject for blood pressure regulation, or an autonomous system of the subject for body temperature regulation. The monitoring device may detect, present, track or predict a disordered condition of the subject using the pressure data, or monitor the integrity of the fluid connection based on the pressure data.

Methods for performing macrophage-enhanced MRI, utilizing a macrophage imaging agent, in a single imaging session are provided. The macrophage imaging agent may be an ultrasmall superparamagnetic iron oxide particle. One embodiment includes administering a macrophage imaging agent to the subject during an administration session then allowing a passage of time sufficient for accumulation of the agent in macrophages of the subject. Subsequently, in a single imaging session, a macrophage-enhanced magnetic resonance image is acquired to target macrophages and a different magnetic resonance image is acquired to target physiological phenomenon other than macrophages. Additional embodiments provide methods wherein the acquisition of a different magnetic resonance image is achieved by vascular-enhanced MRI protocols or perfusion-enhanced MRI protocols, or combinations thereof. Further embodiments provide methods for utilizing acquired images in assessment of treatment of disease.

An integrated cardio-respiratory system that fuses continuously recorded data from multiple physiological sensor sources to acquire signals representative of acoustic events caused by physiological phenomena occurring in the cardiac and / or arterial structures underneath particular areas of the chest and / or neck to monitor cardiac and respiratory conditions.

Passive physiological monitoring apparatus has a sensor for sensing physiological phenomenon and method converter converts sensed data into electrical signals and a computer receives and computes the signals and output computed data for real-time interactive display. The sensor is a piezoelectric film of polyvinylidene fluoride. Signals detected include mechanical, thermal and acoustic signatures reflecting cardiac output, cardiac function, internal bleeding, respiratory, pulse, apnea and temperature. The sensor may be an array provided in a MEDEVAC litter or other device for measuring acoustic and hydraulic signals from the body of a patient for field monitoring, hospital monitoring, transport monitoring, home, remote monitoring.

A mechanical vibration sensor adapted to be brought into contact with an object for sensing mechanical vibrations in the object, includes a body of a soft elastomeric material having high transmissivity and low attenuation properties with respect to a preselected type of energy waves; and a pair of transducers mounted, by mounting members having high attenuation properties with respect to the energy waves, in spaced relationship to each other to define a transmission channel between the transducers. Such sensor is particularly useful in a method and apparatus for controlling snoring by a person, by utilizing a stimulus device effective, when sensing snoring, to immediately produce a response in the person tending to interrupt the person's snoring.

The object of this invention is to elucidate the factors involved in the regulation of AGE (advanced glycation endproducts, which are produced in a living body accompanied with diabetes and aging) and RAGE (the receptor for AGE), in order to facilitate investigation on the biological activities, physiological phenomenon and diseases related to AGE and RAGE. Plural molecular species are known to exist for RAGE, and among such molecular species, soluble RAGE exhibits the activity to modulate interaction between AGE and transmembrane-type RAGE. Using this soluble RAGE or a nucleic acid encoding it, the soluble RAGE can be measured, in addition, investigation on various physiological phenomenon, biological activities, and diseases related to interaction between AGE and RAGE can be performed to facilitate development a medicine having further efficacy.

The present invention provides antibodies or fragments thereof that bind to cancer cells and is important in physiological phenomena, such as cell rolling and metastasis. Therapeutic and diagnostic methods and compositions using such antibody fragments thereof are also provided. The methods and compositions according to the present invention can be used in targeting therapeutic agents and in diagnosis, prognosis, and staging of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease. Also provided is a library of immunoglobulin binding domains having a diverse antigen-binding domain for complementary binding, wherein the library has diversity only in heavy chain CDR3.

The invention belongs to the aquaculture technology field, in particular relating to an artificial control method for the improvement of female finless eel parent fecundity. The finless eel has special physiological phenomena and sex reversal characteristics with small size, large egg granules and low fecundity. Thus the scale finless eel propagation is subject to the restrictions of the female finless eel parent self-conditions. In the invention, through the artificial simulation of female finless eel culture and development environment, the rational selection of parental finless eels, the reasonable stocking density arrangement, the appropriate feeding and management methods, the pre-oviposition period intensive culture and the artificial control measures, the female finless eel fecundity in natural state can be enhanced to the fecundity up to 450 to 1300 grains each and the 680 grains average level from 170 to 650 grains each and the average 260 grains. Therefore, the average fecundity of finless eel is improved by 161%.

The object of this invention is to elucidate the factors involved in the regulation of AGE (advanced glycation endproducts, which are produced in a living body accompanied with diabetes and aging) and RAGE (the receptor for AGE), in order to facilitate investigation on the biological activities, physiological phenomenon and diseases related to AGE and RAGE. Plural molecular species are known to exist for RAGE, and among such molecular species, soluble RAGE exhibits the activity to modulate interaction between AGE and transmembrane-type RAGE. Using this soluble RAGE or a nucleic acid encoding it, the soluble RAGE can be measured, in addition, investigation on various physiological phenomenon, biological activities, and diseases related to interaction between AGE and RAGE can be performed to facilitate development a medicine having further efficacy.

The present invention relates to a device, system and method for pulsatility detection. The proposed device comprises an input interface (30) for obtaining image data of a scene, said image data comprising a time sequence of image frames, an extraction unit (31) for extracting a time-varying signal indicative of a periodic physiological phenomenon from a region of interest of said image data, a transformation unit (32) for transforming said time-varying signal into a spectral signal, a partitioning unit (33) for partitioning the spectral signal into at least an in-band sub-signal covering a first frequency range of said spectral signal and an out-band sub-signal covering a second frequency range of said spectral signal, wherein said first frequency range comprises at least a frequency range of the periodic physiological phenomenon, an analysis unit (34) for separately deriving an in-band measure from the in-band sub-signal and an out-band measure from the out-band sub-signal, the in-band measure and the out-band measure representing a descriptor, and a classifier (35) for classifying said region of interest as a pulsatile region of a living being or as a non-pulsatile region based on the descriptor.

An X-ray computer tomography apparatus of this invention has a function of monitoring, by a pre-scan, a density of a contrast medium in ROI of an object, stopping the pre-scan on the basis of a timing at which the density reaches to a predetermined value, and starting a main-scan. A main-scan condition is initially set based on a physiological phenomenon of the object measured before the injection of the contrast medium. The necessity of resetting an initially set main scan condition is determined on the change of a physiological phenomenon measured before the end of the pre-scan. If it is determined that the main scan condition needs to be reset, the main scan condition is reset from the initially set main scan condition to a main scan condition corresponding to the physiological phenomenon measured before the end of the pre-scan.

A method of processing images of at least one living being, includes obtaining a sequence (19) of digital images taken at consecutive points in time. At least one measurement zone (26) comprising a plurality of image points is selected. For each measurement zone (26), a signal (28,30) representative of at least variations in a time-varying value of a combination of pixel values at least a number of the image points for use in determining at least one of a presence and a frequency value of at least one peak in a spectrum of the signal (28,30) corresponding to a frequency of a periodic physiological phenomenon is obtained. The step (25) of selecting at least one measurement zone (26) includes analyzing information based on pixel data of a plurality of image parts in at least one of the images (19), each image part including at least one image point, and selecting each measurement zone (26) from contiguous parts determined to have similar characteristics.

The invention discloses a blood circulation demonstrating device. The blood circulation demonstrating device is characterized in that all demonstrating parts which are arranged on one lateral side of a vertical plate of a support and represents physiological structures of a blood circulation system of an animal are hollow and are connected in sequence to form a closed pipeline, the pipeline is filled with liquid, both an atrium demonstrating part and a ventricle demonstrating part are made of elastic materials, and a transmission mechanism enabling the atrium demonstrating part and the ventricle demonstrating part to contract and relax in an alternating mode is arranged on the other lateral side of the vertical plate. The blood circulation demonstrating device can visually and vividly represent the relevant physiological structures and physiological phenomena of the blood circulation system of the animal.

A method for avoiding physiological phenomena such as color separation or stroboscopic effects that occur under boundry conditions in the case of intermittent feeding in particular of light-emitting diodes, for additive superposition to form color-locus-variable mixed light, whereby the emission brightness that can be represented by a periodic duty ratio of a pulse-time-modulated constant current feeding—preferably within the respective period—is realized by changeover to other or between different constant current intensities in such a way that a brightness equivalent, namely once again the current-time integral of the predetermined, brightness-determining duty ratio, arises in the current area sum, which now preferably no longer exhibits gaps over the period.

A method and apparatus for providing an average signal characteristic profile derived from signals obtained from different cycles of a cyclically recurring physiological phenomenon. A signal produced from first and second cycles of the physiological phenomenon is sampled at a series of data points to obtain second physiological property values at the data points. The change in the second physiological property values for the first cycle signal between a pair of successive data points and the change in the second physiological property values for the second cycle signal between the same pair of successive data points are determined and averaged. The average change amount is applied to a value of the average signal characteristic profile at one of the pair of successive data points to produce a new second physiological property value for the average signal characteristic profile at the other of the data points of the pair.

The invention relates to an ecological protection method for preventing the summer donnancy of halaxylon ammodendron forest, which belongs to the field of forestry ecological cultivation science. Because of the forest land condition, the summer donnancy of halaxylon ammodendron (or haloxylon persicum) occurs for many years, but the underground water supply of the shallow forest ground layer is rich. Various plants and seeds thereof applicable to desert or semidesert environment growth and commonly in concomitance with the halaxylon ammodendron (or haloxylon persicum) are adopted for sowing in a circle with the radius about 50 cm around the base part of the root and stalk of the halaxylon ammodendron (or haloxylon persicum), and more than 200 seeds are sowed per square meter. Through the invention, the halaxylon ammodendron (or haloxylon persicum) can still grow normally under the extreme adverse environment conditions in summer, and the physiological phenomenon of summer donnancy does not occur, so the fast growth of the individual plants of the halaxylon ammodendron (or haloxylon persicum) is promoted, and the annual growth quantity is increased. The invention has the advantages of strong operability, good repeatability, high efficiency and simple method, and has the significant meaning for the ecological restoration reconstruction of the desert or semidesert large-scale halaxylon ammodendron (or haloxylon persicum) forest in China.

The X-ray computed tomography apparatus of the present invention has a function of monitoring the concentration of a contrast agent in an ROI of a subject by a pre-scan, stopping the pre-scan according to the time when the concentration reaches a predetermined value, and starting a main scan. The main scan conditions are initially set based on the physiological phenomena of the subject measured prior to injection of the contrast medium. Whether it is necessary to reset the originally set main scan conditions is judged based on the changes in the physiological phenomena measured before the end of the pre-scan. If it is determined that the main scan condition needs to be reset, the main scan condition is reset from the initially set main scan condition to the main scan condition corresponding to the physiological phenomenon measured before the end of the pre-scan.

The invention relates to a physical protection method for preventing summer dormancy of haloxylon ammodendron forest, belonging to the field of ecological cultivation of forestry. Years haloxylon ammodendron or haloxylon persicum forest land has abundant shallow ground water supply; and general material, such as straw screens, straws, wheat straws or straw ropes and the like and organic heat insulation materials, such as polystyrene board and the like are chosen. The materials are applied all over the year and are maintained once before summer dormancy to ensure that the base of the root and the stem of the haloxylon ammodendron or haloxylon persicum are effectively separated from shallow ground matrix. The method can ensure that the haloxylon ammodendron (or haloxylon persicum) can normally grow under the extreme adverse circumstance in summer, generates no 'summer dormancy' physiological phenomenon and quickens the growth of artificial haloxylon ammodendron (or haloxylon persicum). The invention has strong maneuverability, favorable repeatability, high efficiency and simple method and has an important meaning for large-scale ecological restoration and reconstruction of haloxylon ammodendron (or haloxylon persicum) forest in desert and semi-desert in China.

A method and apparatus for providing an average signal characteristic profile relating first and second physiological properties, the average signal characteristic profile being derived from signals obtained from different cycles of a cyclically recurring physiological phenomenon. A signal produced from a first cycle of the physiological phenomenon is sampled at a series of data points of a first physiological property to obtain second physiological property values of the first cycle signal at the data points. The signal produced from a second cycle of the physiological phenomenon is sampled at a series of data points corresponding to those of the first series of data points to obtain second physiological property values of the second cycle signal at the data points. The change in the second physiological property values for the first cycle signal between a pair of successive data points and the change in the second physiological property values for the second cycle signal between the same pair of successive data points are determined and averaged to produce an average change amount for the successive data points. The average change amount is applied to a value of the average signal characteristic profile at one of the pair of successive data points to produce a new second physiological property value for the average signal characteristic profile at the other of the data points of the pair.

The present invention relates to a mutant microorganism producing a high concentration of L-threonine in high yield, prepared using site-specific mutation, not random mutation, such as treatment with a mutation inducer, a method for preparing the same, and a method for preparing L-threonine using the mutant microorganism producing L-threonine. By using the mutant microorganism according to the present invention, L-threonine can be prepared at high yield, additional strain development becomes possible and their physiological phenomena can be easily understood since genetic information of L-threonine producing microorganism can be identified.

The invention discloses a field device for biologically monitoring water quality online. The defects that tested organisms need to be fed by foods, the tested organisms need to be replaced periodically, monitoring is limited to a specific monitoring site and medium / long-term online biological monitoring cannot be realized in the conventional online water quality biological monitoring are overcome. The scientific requirements of medium / long-term biological monitoring early warning which reflects water toxicity change in a natural water body can be met. According to the device, a rule that hyriopsis cumingii can be subjected to hanging culture in lakes and reservoirs for ingesting plankton and a physiological phenomenon that the shell of the hyriopsis cumingii is tightly closed after the hyriopsis cumingii is stressed are fully utilized, and the shell motion of the hyriopsis cumingii is induced by using a sensor fixed on the shell of the hyriopsis cumingii, so that the biological toxicity monitoring of the water quality is performed. According to the device, a floating platform and a floating ball are fixed on a monitoring site by utilizing a mooring anchor, a signal emitter is supported by buoyancy supporting the floating platform, and the hyriopsis cumingii and the sensor are supported by utilizing buoyancy of the floating ball, so that the hyriopsis cumingii and the sensor are suspended in the water body. The shell closing response of the hyriopsis cumingii is induced by utilizing the sensor, a signal is transmitted to the signal emitter through a wire, the signal is received by utilizing a signal receiver arranged ashore for performing analytical processing, and the water quality is subjected to scientific early warning and monitoring.

The invention discloses a simulated infant human body experimental model. The simulated infant human body experimental model comprises a skeleton system, a balance weight layer, a functional layer and a skin layer, wherein the balance weight layer is arranged in a cavity of the skeleton system; the functional layer is arranged on the outside of the skeleton system; the skin layer is arranged on the outside of the functional layer; the skeleton system has a retractable structure; and the functional layer comprises a heating layer, a heat-insulation layer, an insulated layer and a humidifying layer which are successively arranged from inside to outside. The skeleton system has the retractable structure, and the height of the human body model can be regulated; the functional layer can control the temperature to be within a normal body temperature range, temperature difference between different parts of a human body can be embodied, a human body perspiration function can be simulated, and physiological phenomenon of human body perspiration can be simulated; and the skin layer can breathe freely, and has high mechanical strength, individual parts can be subjected to micropore treatment to meet high requirement of breathability, weather fastness, water repellency and electric insulation performance are good, and circuit accidents can be completely eradicated effectively.

The invention discloses a multi-particle hybrid modified thrombus simulation method based on a Cross model. A multi-particle hybrid modified SPH method based on the Cross model is utilized to simulatethe blood, so a problem that the phenomenon that large-mass particles sinks downwards and small-mass particles rise upwards in the simulation process does not conform to the normal blood physiological phenomenon is solved, a particle-by-particle polymerization method is utilized to simplify a thrombus model to simulate thrombus formation, and a problem that a traditional method can not simulate thrombus formation of the blood is solved. The method is advantaged in that the blood can be more realistically simulated, and thrombus formation of the blood can be further simulated. Through correctly simulating thrombus formation, the thrombus study is facilitated, the method can be applied to medical applications such as virtual surgery and medical assistant research, moreover, needs of relatedaspects in game and film industries can be satisfied.

Process and electrostimulation equipment employed in the control of headaches, said process predicting the development of an electrostimulation protocol in which the variation of electric pulse variation is made in a random manner to reduce the physiological phenomenon of nerve fiber accommodation upon stimuli; portable electrostimulation equipment, formed by an electrostimulation set and support is provided, the former consisting of a cylindrical compartment housing an electric circuit board and disposable coin-shaped lithium-ion battery, model CR20XX, in whose back face there are recesses, which house the respective electrodes, suitably covered by respective gel layers protected by removable protective sheets; the electrostimulation set being engaged with the medial longitudinal groove of the support, which configures the rail along which aid set is moved; the following internal components are also provided: Power source module, step-up regulator module, micro controller module, power supply seal module, boost source module, H-bridge module, and electrode output module.