5 results about "Hormone drug" patented technology

This invention belongs to the field of biomedicine, specifically relating to siRNA that inhibits AR gene expression, comprising a sense strand and an antisense strand, wherein the sense strand and the antisense strand are at least partially anticomplementary to form a double-stranded region, and the sense strand or antisense strand consists of 19-25 nucleotides with blunt ends of complementary nucleotide sequences; or the antisense strand consists of 27 nucleotide sequences with overhangs. The siRNA of this invention can maintain long-term efficacy with a single dose, exhibiting good compliance in patients with chronic diseases such as androgenetic alopecia. Furthermore, it has lower off-target toxicity and fewer side effects compared to small molecule chemical drugs and hormone drugs.

The present application belongs to the field of musk deer breeding, and discloses a kind of musk deer feed and its feeding method in breeding, aiming at solving the problem of few kinds of musk deer feed in the market, and the problem of short musk deer producing time, harmful components in musk etc. caused by unbalanced nutrition and excessive addition of hormone drugs. The present application is composed of agaric, fish meal, silkworm chrysalis, yeast, soybean meal, peanut meal, corn, salt and compound vitamin. The musk deer feed is prepared by mixing agaric, fish meal and silkworm chrysalis with yeast, and then the musk deer is fed by increasing the amount of feed day by day. The musk deer feed provided by the present application changes under the action of microorganisms, so that the raw materials can play a synergistic effect. After the musk deer feeds on the feed for several months before producing musk, the musk deer becomes stronger, more active, secretes more male hormones, has stronger sexual ability and stronger musk secreting ability, so that the musk producing amount is increased.

The present application belongs to the technical field of biological medicine, and particularly relates to a pyruvate preparation for asthma treatment and a preparation method thereof. The pyruvate preparation comprises the following components in parts by weight: 10-12 parts of pyruvate, 10-12 parts of sodium chloride, 0.5-1 part of citric acid, and 500 parts of water for injection; and the pH of the pyruvate preparation is 6-7. The pyruvate preparation is used for daily management of asthma patients, can control the increase of inflammatory cells such as eosinophilic granulocyte, reduce inflammatory reaction, and thus achieve the purpose of inhibiting asthma. The effect of the pyruvate preparation is close to that of the same kind of hormone drug dexamethasone, and the pyruvate preparation can achieve the treatment purpose while reducing the dependence of patients on hormone drugs and side effects.

The present application provides a kind of lentinan and its preparation method and application, lentinan preparation method includes: preparation method includes: after crushing lentinan raw material, auxiliary extraction is carried out by adding composite enzyme, decoction 3-5h, filter to obtain lentinan intermediate, then add alpha-glucosidase and beta-glucosidase to obtain reaction liquid, stir to 40-45 ℃, dry to obtain lentinan.The lentinan prepared by the lentinan preparation method of the present application has high activity and meets the quality requirements of lentinan characteristic atlas, the method does not remove protein and alcohol precipitation, can be mass-produced and reduces production cost.The lentinan is modified by using composite enzyme assisted extraction and alpha-glucosidase and beta-glucosidase, which improves the extraction efficiency, and the lentinan obtained has higher activity than ordinary lentinan, which can be used for the treatment of skin disease in pigs, reduces the use amount of hormone drugs, and reduces the drug residue in the body of pig.

The application discloses a traditional Chinese medicine capsule of Herba Epimedii and Radix Morindae Officinalis and a preparation method thereof, relates to the technical field of traditional Chinese medicine preparations, and overcomes the defects of single-component preparation target, large side effect of hormone-containing drugs and unreasonable traditional compound prescription, etc.