The invention discloses lithiases-eliminating 
earthworm medicinal-liquor and a preparation method thereof, and belongs to the field of 
traditional Chinese medicine compositions. The lithiases-eliminating 
earthworm medicinal-liquor is prepared from the following raw materials: herba lysimachiae, 
stigmata maydis, Japanese climbing 
fern spore, 
coix seeds, ricepaperplant 
pith, sweet wormwood 
herb, 
earthworm, walnut kernels, radix scutellariae, poria cocos, oriental waterplantain rhizomes, largeleaf gentian roots, Chinese gentian, cortex eucommiae, Chinese wolfberry fruits, pilose 
antler, mulberryfruits, Chinese angelica roots, rhizoma polygonati, herba dendrobii, 
American ginseng, and 
ganoderma lucidum. The preparation method of the lithiases-eliminating earthworm medicinal-liquor comprises the following steps: respectively cooking part of the 
traditional Chinese medicine materials with water and liquor; and then, soaking the cooked materials with liquor. More specifically, the preparation method of the lithiases-eliminating earthworm medicinal-liquor comprises the following steps: respectively cooking part of the 
traditional Chinese medicine materials, which contain 
aromatic hydrocarbon and volatile oil, with water and liquor so as to have the substances dissolved; and then, carrying out soaking. Being cooked with the liquor, beneficial substances can be better dissolved, so thatbody 
metabolism and 
endocrine functions can be improved so as to achieve liver protection effects. Moreover, the ithiases-eliminating earthworm medicinal-liquor has the effects of resisting oxidationand delaying senility, and is obvious in anti-
inflammation and anti-tumor effects; and the ithiases-eliminating earthworm medicinal-liquor has certain protective effects on 
organ damage, and is capable of improving 
metabolism and enhancing immune functions.