9results about How to "Regulate metabolism" patented technology

The invention relates to the technical field of biological material manufacturing, in particular to vanadium-doped mesoporous bioactive glass powder for treating diabetic wounds and a preparation method of the vanadium-doped mesoporous bioactive glass powder. Adding an ammonia solution into the template agent solution to obtain a mixed solution; adding a silicon source, a phosphorus source, a calcium source and a vanadium source into the mixed solution in batches according to a preset interval time under a continuous stirring condition, continuously stirring and reacting for 5.5-24 hours, and centrifuging and collecting a precipitation product; and washing, roasting and grinding the obtained precipitation product to obtain the vanadium-doped mesoporous bioactive glass powder for treating diabetic wounds.

The invention provides shampoo for controlling oil and relieving itching and a preparation method thereof, and relates to the technical field of shampoo. The shampoo is prepared from the following raw materials in parts by weight: 10 to 14 parts of camellia oil, 20 to 30 parts of plant extract, 7 to 10 parts of euglena parviflora root powder, 3 to 6 parts of vitamin E, 10 to 13 parts of butyrospermum parviflora butter, 6 to 8 parts of hydrolyzed silk protein, 7 to 9 parts of euglena parviflora polysaccharide, 4 to 7 parts of amino acid, 14 to 18 parts of surfactant, 2 to 4 parts of hydroxyethyl cellulose and 70 to 90 parts of water. The shampoo has good foaming and scalp dirt cleaning performance and can inhibit excessive secretion of sebaceous gland cells and reduce scalp grease generation, active ingredients can permeate into the inner layer of scalp to supplement moisture and nutrition, meanwhile, a protective layer can be formed on the surface layer of the scalp, the damaged scalp barrier of children is repaired, the scalp resistance is enhanced, and the hair is protected. Therefore, good oil control and itching relieving effects are achieved, and the effect is mild.

The invention discloses a constructed wetland pollution reduction and carbon reduction synergistic effect analysis system and method, and relates to the technical field of water pollution control and greenhouse gas emission reduction. Comprising a simulated wetland reaction unit, a multi-parameter monitoring module, an operation regulation and control module, a microbiological analysis module and a synergistic effect evaluation module. The simulated wetland reaction unit is filled with a FeC composite matrix to realize subsurface flow constructed wetland environment simulation; the multi-parameter monitoring module acquires water quality and greenhouse gas emission data in real time; the operation regulation and control module realizes accurate regulation and control of water inlet parameters; the microbiological analysis module analyzes microflora and functional gene information; and the synergistic effect evaluation module integrates multi-module data to construct a correlation model, calculates a synergistic effect index and outputs an optimization parameter. Through five stages of matrix optimization, operation regulation and control, microbial mechanism revealing, collaborative evaluation optimization and feedback application, evaluation and optimization of the constructed wetland pollution reduction and carbon reduction collaborative efficiency are realized, and a scientific basis is provided for actual constructed wetland engineering design and operation.

The application discloses a method for applying lanthanum as a passion fruit cadmium reduction agent and improving fruit quality, which comprises the following steps: during the young fruit period to the mature period of the passion fruit, a compound regulation agent prepared from La(NO3)3 and water is sprayed on the leaves; the concentration of La(NO3)3 in the compound regulation agent is 40-53.3 mg / L in terms of La; the spraying is performed three times, and the first spraying is preferably performed during the young fruit formation period, the second spraying is performed during the initial swelling period, and the third spraying is performed during the early fruit filling period. Through scientific spraying of the lanthanum nitrate in the Cd-polluted soil, the passion fruit can be stably grown, the Cd accumulation amount of the fruit and the plant can be significantly reduced, the sugar and acid constitution, the vitamin C content and the antioxidant enzyme activity of the fruit can be improved, and the fruit quality and the stress resistance can be ensured.

This invention belongs to the fields of biomedical materials and colloid chemistry, and discloses a structurally remodeled egg yolk low-density lipoprotein biomimetic liposome and its application in regulating cholesterol metabolism. The method includes extracting and purifying natural egg yolk low-density lipoprotein; selectively removing endogenous cholesterol by adding β-cyclodextrin under alkaline conditions; adding a phytosterol ethanol solution to the cholesterol-removed low-density lipoprotein dispersion, followed by incubation and dialysis purification to obtain the biomimetic liposome. The obtained biomimetic liposome uses partially cholesterol-removed egg yolk low-density lipoprotein as its structural framework, with phytosterols embedded in its phospholipid monolayer and lipid core interface. This biomimetic liposome can inhibit cholesterol micelle formation, reduce cholesterol absorption, promote macrophage cholesterol efflux, and inhibit macrophage foam formation. It can be used to prepare cholesterol metabolism regulating materials, functional delivery systems, and dietary supplement products.

The application discloses a pH-responsive deformable double-targeting nano-protein and a preparation method and application thereof, and the method comprises the following steps: after carboxylated mannose is activated through an EDC / NHS system, the carboxylated mannose is reacted with an albumin solution, and mannose-modified albumin is obtained through dialysis purification; the mannose-modified albumin is mixed with an inhibitor IRG1-IN-1, and IRG1-IN-1 is loaded through hydrophobic interaction to obtain mannose albumin nanoparticles; ferritin is used as a carrier, and oxaliplatin is loaded through a solvent displacement method to obtain ferritin nanoparticles; CHO-PEG2k-CHO is used as a connecting agent, and the mannose albumin nanoparticles and the ferritin nanoparticles are crosslinked through a Schiff base reaction to form large-size pH-responsive double-targeting nano-proteins. The double-targeting separable characteristics of the nano-proteins can realize specific treatment, kill tumor cells, interfere with immune cell metabolism, block metabolic immunosuppression, and promote anti-tumor immunotherapy.

The application discloses poplar phellinus polysaccharide SVP-50-1 and a preparation method and application thereof, and belongs to the field of biological medicines.The poplar phellinus polysaccharide SVP-50-1 is obtained by water extraction and 50% ethanol solution precipitation of poplar phellinus fruiting bodies.The poplar phellinus polysaccharide SVP-50-1 can regulate a tumor metabolic process, inhibit the activity of a tumor cell mitochondrial respiratory chain and an oxidative phosphorylation process, thereby inhibiting the energy source of tumor cells, and achieving an anti-tumor effect.The poplar phellinus polysaccharide SVP-50-1 can play a synergistic effect when combined with radiotherapy and chemotherapy drugs.The combined treatment strategy can significantly improve the curative effect of an existing tumor treatment, while reducing adverse reactions, and provides a new optimized scheme for clinical tumor treatment.

The invention relates to instant silkworm chrysalis and a preparation method thereof. The method comprises the following steps: inoculating activated cordyceps militaris bacteria to a liquid culture medium for amplification culture to prepare a cordyceps militaris bacteria solution; the cordyceps militaris bacterium liquid is inoculated into silkworm chrysalis bodies, stiffening treatment and fermentation culture are sequentially conducted, fermented silkworm chrysalis is obtained, the stiffening treatment temperature ranges from 15 DEG C to 17 DEG C, the stiffening treatment time ranges from 4 d to 6 d, the fermentation culture temperature ranges from 20 DEG C to 23 DEG C, and the fermentation culture time ranges from 8 d to 11 d; and performing high-temperature treatment or freezing treatment on the fermented silkworm chrysalis, and cooking to prepare the instant silkworm chrysalis. The temperature of the high-temperature treatment is 100 to 120 DEG C. Deodorization, desensitization, nutrition modification, active ingredient enrichment and flavor improvement are synchronously realized, and the ready-to-eat silkworm chrysalis is prepared.

This invention provides a composition for improving bone density, its preparation method, application, and product, belonging to the technical field of bone and joint health products. The composition for improving bone density comprises the following components in parts by weight: 0.1-70 parts collagen peptides; 0.01-2 parts casein phosphopeptides; 7-40 parts milk mineral salts; 0.5-40 parts fructooligosaccharides; and 0.01-1 parts vitamin D. In the composition provided by this invention, the casein phosphopeptides, vitamin D, fructooligosaccharides, collagen peptides, and milk mineral salts can interact to increase bone calcium and bone density, thus preventing or improving osteoporosis.