The invention discloses an industrial preparation method for calcium carbonate nanometer beads, which is an industrial preparation method for nanometer calcium carbonate with a bead-shaped structure, and comprises the following steps that: (1) natural limestone is crushed and calcined, then is added with hot water for digestion, and passes through a sieve for refining to be prepared into a refined calcium hydroxide material liquid; (2) the calcium hydroxide slurry is sent into a reactor system, proper kiln gas is aerated for carbonization reaction, the concentration of carbon dioxide in the kiln gas is between 10 and 50 percent, and a crystal control agent composition A and a crystal control agent composition B are added before the carbonization or at an initial carbonization stage; and (3) an obtained product is filtered, dried and crushed to obtain the bead-shaped nanometer calcium carbonate. The diameter of the bead-shaped nanometer calcium carbonate is between 20 and 50nm, the slenderness ratio is between 10 and 30, and the BET specific surface area is larger than 30m/g. The bead-shaped nanometer calcium carbonate has good dispersivity, improves the mechanical property of materials, and improves the barrier property of the materials to various gases and liquids, so the bead-shaped nanometer calcium carbonate can be widely applied to industries such as rubber, plastic, coating, printing ink, paper making, sealing gum and the like.