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The mean weight of the normal prostate in adult males is about 11 grams, usually ranging between 7 and 16 grams. A study stated that prostate volume among patients with negative biopsy is related significantly with weight and height (body mass index), so it is necessary to control for weight.
Prostate targeting adeno-associated virus serotype vectors
The disclosure relates to compositions and methods for rAAV-mediated delivery of a transgene to a subject. In some embodiments, the rAAV transduces the prostate tissue of a subject. In some embodiments, the methods are useful for treatment of prostate disease (e.g., prostatitis, BPH, prostate cancer).
Owner:UNIV OF MASSACHUSETTS