The invention discloses a combined medicine for conditioning internal and external conditions of upper jiao (shoulders, neck and upper limbs) or lower jiao (waist, legs, lower abdomen and pelvic cavity) diseases and a preparation method thereof. The combined medicine is prepared by taking dried ginger, astragalus membranaceus, angelica sinensis and liquorice as main medicines and borneol, menthol,traditional Chinese medicine camphor, cinnamon, clove, gallnut, chicken blood, cortex acanthopanacis, lycopodium clavatum, cassia twig or achyranthes bidentata and phaseolus calcaratus as auxiliary medicines through a certain method. The combined medicine has the effects of warming and dispersing, warming and dredging, warming and nourishing the interior and exterior and regulating, and achievesthe effects of dispelling cold, removing blood stasis, relieving pain, promoting blood circulation, stimulating menstrual flow, dredging collaterals, dispersing blood stasis and diminishing swelling.The combined medicine can be used for conditioning diseases such as joint soreness, numbness, pain, swelling, dyskinesia and rheumatic arthralgia of muscles of neck, shoulders and upper limbs or conditioning diseases such as joint soreness, numbness, pain, swelling and dyskinesia of muscles of waist, buttocks and lower limbs, and diseases of hypogastrium, pelvic cavity and the like.