37 results about "Prostatic fluid" patented technology

Methods, systems, and computer program products for obtaining a sample in vivo and / or treating a subject include positioning an elongated transurethral catheter in the prostatic urethra of a subject, the catheter having a bladder anchoring balloon, at least one biosample entry port disposed axially away from the bladder anchoring balloon, and an axially extending biosample flow channel in fluid communication with the biosample entry port held internally in the catheter. The anchoring balloon is inflated to position the catheter so that the fluid entry port is proximate the prostatic urethra of the subject and prostatic fluid is suctioned from the prostatic urethra into the biosample entry port and into the biosample flow channel. The catheter can include a thermal treatment balloon and / or dilatation balloon and the suctioned sample can be obtained concurrently with, during, or proximate in time to the applied treatment. The catheter can be configured to allow urine to drain therethrough during the treatment / collection of the sample while keeping the urine isolated from the collected prostatic fluid sample.

The invention provides a hygienic urine collection device used for medical examination. The device includes a ultraviolet germicidal lamp, a second sealed line connection hole, a modulator tube protection cover, an urine lead-out electromagnetic valve, an urine containing test tube, a supporting transverse plate, a touch control panel and an urine groove top cover lock catch; three stable supporting plates are supported on a bottom plate through welding, and the top of the bottom plate is provided with a supporting bulge through welding in a protruding mode; the side walls of the left side and the right side of the supporting bulge are obliquely arranged in a slicing mode, the two oblique side walls are symmetrically provided with two inner grooves, and the two symmetrical inner grooves are internally and rotatably provided with an ascending pedal and a descending pedal in a supporting mode. A transversely-placed supporting frame is supported on the side wall of a cleaning water tank through welding, and a water-tank water inlet pipe is fixedly supported on a connection transverse plate at the top of the transversely-placed supporting frame. Through the arrangement of the cleaning water tank, the glans penis and the urethral orifice can be cleaned in the cleaning water tank, seminal fluid and prostatic fluid are prevented from being mixed with collected urine to contaminate the urine, and the accuracy of subsequent inspection data is affected.

The present invention provides methods of determining if an individual is at risk for prostate cancer. The methods measures and compares free and / or bound zinc levels in a semen sample or prostatic fluid, including post massage expressed prostatic fluid, in the potential at risk individual with normal levels. A decrease in zinc level is indicative of a risk for prostate cancer.

The invention provides a method for testing prostate-fluid free heme. The method comprises the following steps: obtaining prostate-fluid seepage fluid; processing the seepage fluid with a trismetyl aminomethane-hydrochloric acid buffer solution with the PH being 7.4; and reacting with a color reagent, comparing with a shade guide, and recording test results. The method is simple and practical, is low in cost, and can rapidly screen samples without heme, samples with heme, and samples probably containing heme in cervical seepage fluid to make preparations for further screening. Meanwhile, the invention also relates to a test kit for testing prostate-fluid seepage fluid.

The invention discloses a prostate therapeutic apparatus. The prostate therapeutic apparatus comprises a massaging head for massaging the prostate, a connecting handle connected with the massaging head and a driving device for driving the massaging head, and further comprises a collecting container used for collecting prostatic fluid and connected at the other end of the connecting handle. An opening is formed in the surface of the massaging head, and the connecting handle comprises a channel used for leading the prostatic fluid into the collecting container. The relative positions of the connecting handle and the massaging head can be adjusted, and the connecting handle is provided with an opening which corresponds to the opening in the surface of the massaging head; when the opening in the connecting handle and the opening of the massaging head are in the same position, the prostatic fluid can be led out through the openings, and when the opening of the connecting handle and the opening of the massaging head are not in the same position, the prostatic fluid cannot pass through the openings.

The invention relates to prostatic cancer markers from a prostatic secretion, and discloses a group of new prostatic cancer markers comprising Haptoglobin alpha-chains, Fibronectin1, Albumin and / or SERPINB1. In the prostatic secretion, the expression of the above proteins in prostatic cancer patients is substantially higher than the expression in non-cancer patients, so reagents or kits for the diagnosis, the assessment and the prognosis of the prostatic cancer can be developed based on the proteins.

The invention provides a male chronic prostatitis / chronic pelvic pain syndrome pain severity prediction model and establishment thereof, and relates to the field of chronic prostatitis / chronic pelvicpain syndrome pain severity prediction. The pain severity prediction model is established by adopting an advantage ratio OR of variables such as the age of a patient, the level of lecithin bodies in prostatic fluid, urine suppression, anxiety or irritability, contraception, smoking and the like, establishing a column diagram as a model to predict the pain severity of the CP / CPPS patient on the basis of the confidence intervals of 2.5% and 97.5% and the P-value. Establishment of the model mainly comprises the steps of material selection, grouping, variable screening, variable analysis and the like. According to the method, the defects in the prior art are overcome, the pain level of prostatitis can be accurately predicted by establishing the model, and meanwhile, the clinical decision-making efficiency is improved.

The invention discloses an intra-rectal balloon-type ultrasonic prostate treatment head, belonging to the technical field of medical instruments. The treatment head includes a rod body for inserting into the rectum of a human body, wherein the rod body is of a hollow structure having an open end and the side wall of the rod body is provided with a with notch. The treatment head further includes aballoon arranged in the rod body and a conversion housing fixedly connected with the open end of the rod body, wherein an ultrasonic transducer is fixed in the conversion housing, the open end of theballoon and the open end of the rod body are sealed and fixed and communicates with the inside of the conversion housing, and the balloon is inflated by the water that is charged into the balloon by the conversion housing so that the free end thereof is ejected from the notch of the rod body to be in close contact with the prostate. The heating effect is better and the safety is higher; while thethermal therapy is performed, ultrasound is also used for treatment, so that the treatment effect is better. When obtaining prostatic fluid for clinical prostatic fluid routine examination, manual operation by a doctor is not needed, so that the prostate treatment head is more user-friendly, and the balloon can accurately contact with the prostate to reduce the pain and other discomfort of a patient.

The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method of the composition. The composition comprises the following components in parts by weight: 2-20 parts of rhizoma dioscoreae hypoglaucae, 2-20 parts of rhizoma acori graminei, 2-40 parts of pumpkin seed, 2-20 parts of ardisia japonica, 2-40 parts of semen coicis, 2-20 parts of dandelion, 2-40 parts of fructus alpiniae oxyphyllae, 2-20 parts of flatstem milkvetch seed, 2-20 parts of the fruit of Chinese wolfberry, 2-20 parts of spina gleditsiae, 2-20 parts of the seed of Chinese dodder, 2-40 parts of lindera aggregate and 2-40 parts of semen plantaginis. The composition can be prepared into powder or tea bags in dosage form. The preparation method comprises the following steps: crushing, baking, disinfecting and sterilizing the raw material medicines, thereby preparing the powder or the tea bags. The clinical tests show that the traditional Chinese medicine composition disclosed by the invention has the effects of tonifying deficiency, breaking stagnation to generate fresh, invigorating the kidney, strengthening Yang and the like, can improve the immunity of the organism and improve the state of prostatic fluid, is beneficial for fertilization, is rapid and stable to take the curative effect into play, is free of toxic or side effect and is a traditional Chinese healthcare medicine for treating chronic prostatitis.

The present invention provides a method of diagnosing whether a subject suffers from benign prostatic hyperplasia (BPH), the method comprising obtaining a prostatic fluid sample from the subject, and analyzing the prostatic fluid sample to detect the presence or absence of a BPH protein marker to determine Whether the subject has BPH. The present invention further provides a method of diagnosing whether a subject suffers from benign prostatic hyperplasia (BPH), the method comprising obtaining a serum sample from the subject, and analyzing the serum sample to detect the presence or absence of a BPH protein marker to determine whether the subject is suffering from benign prostatic hyperplasia (BPH). Whether the test subject has BPH. Finally, the present invention provides a diagnostic kit for detecting benign prostatic hyperplasia (BPH) markers containing BPH protein markers and instructions for use.

The invention provides application of periplaneta Americana to preparation of a medicine for treating prostatitis. The medicine can reduce the WBC content in prostatic fluid of prostatitis patients and decrease inflammatory factors in prostatic fluid of the prostatitis patients, and prostatitis refers to IIIA prostatitis. The medicine contains a periplaneta Americana extract, levofloxacin and tamsulosin which are simultaneously or separately fed. Clinical test results show that the medicine has the clinical effective rate of up to 73.53% on IIIA prostatitis patients, and can remarkably reduce contents of WBC, TNF-alpha and IL-10 in prostatic fluid of the IIIA prostatitis patients.

The invention discloses a method for detecting damage of mitochondria in prostate gland cells. The method comprises the following detection steps: extracting 1-2ml of prostatic fluid, adding the prostatic fluid into a sample bottle filled with a buffer solution, and sequentially adding 1ml of a reagent A and 1ml of a reagent B into the sample bottle; and uniformly mixing, observing color change in 2 minutes, comparing the color change with a colorimetric plate, thus obtaining a detection result. The method is simple, practical, quick and high in sensitivity.

The invention discloses a medicine composition for treating prostatitis, and belongs to the technical field of traditional Chinese medicine. The medicine composition is prepared from folium artemisiae argyi, astragalus membranaceus, golden cypress, dried rehamnnia roots, belvedere fruits, rhizoma smilacis glabrae, rainbow conk, akebiaquinata, plantain herb, Chinese yam and liquorice. According to the medicine composition, the total number of leukocytes in non-bacterial or bacterial prostatic fluid of a rat can be effectively decreased, the density of lecithin bodies in the prostatic fluid of the rat is increased, the wet weight coefficient of the rat gland is decreased, and the remarkable treatment effect on the prostatitis is achieved. The medicine composition further has the effects of clearing away heat and toxic materials and the like, and rehabilitation of a patient suffering from the prostatitis is facilitated.

The invention discloses a prostatic fluid obtaining instrument, and belongs to the technical field of diagnosis. The prostatic fluid obtaining instrument comprises a vibrator, wherein the shape of the vibrator is matched with the shape of the bladder of a human body, one end of the vibrator is a vibration end used for carrying out massaging stimulation on the prostatic region of the human body, the other end of the vibrator is an operating end used for realizing the operation for obtaining prostatic fluid, the end part of the vibration end is a ball-shaped detection part, a probe capable of realizing 360-degree imaging is arranged inside the detection part, the operating end is provided with a holding part, and a driving power supply is arranged in the vibrator. The prostatic fluid obtaining instrument is provided with the electric vibrator, in addition, the vibration section is provided with a plurality of bulges, the stimulation effect on the prostatic region of the human body can be improved, the prostatic fluid obtaining effect is improved, the electric mode is used for replacing a manual mode, and medical personnel can be liberated from painful finger pressing work; in addition, the prostatic fluid obtaining instrument has the advantages that the structure is simple, the operation is convenient, safety and reliability are realized, and the obtaining efficiency is high.

This invention provides a method for determining whether a subject is afflicted with Benign Prostate Hyperplasia (BPH) comprising obtaining a sample of prostatic fluid from the subject and analyzing the sample of prostatic fluid to detect the presence of BPH protein markers to determine whether the subject is afflicted with BPH. This invention further provides a method for determining whether a subject is afflicted with Benign Prostate Hyperplasia (BPH) comprising obtaining a serum sample from the subject and analyzing the serum sample to detect the presence of BPH protein markers to determine whether the subject is afflicted with BPH. Finally, this invention provides a diagnostic kits for detecting Benign Prostate Hyperplasia (BPH) markers comprising BPH protein markers and instructions for use.

The invention belongs to the field of medical instruments, and particularly relates to a prostatic fluid collector which comprises a conical container bottle, a circular fluid collection opening is formed in the top of the conical container bottle, the diameter of the circular fluid collection opening is 5-15 cm, a fluid collection cover is detachably installed on the circular fluid collection opening, a circular fluid leakage opening is formed in the bottom of the conical container bottle, and the diameter of the circular fluid leakage opening is 5-15 cm. The diameter of the circular liquid leakage opening ranges from 2 mm to 8 mm, and a blocking cover is detachably installed on the circular liquid leakage opening. According to the prostatic fluid collector disclosed by the invention, the problems that the prostatic fluid is difficult to accurately collect and the collected prostatic fluid is difficult to lead out in the existing detection and collection bottle are solved.

The invention provides a method and a device for automatically analyzing a prostatic fluid. The method for automatically analyzing the prostatic fluid comprises the following steps: an image acquisition unit acquires an initial image formed by a prostatic fluid glass slide under a microscope and transmits the image to an image analysis unit; and the image analysis unit analyzes the initial image and forms a recognition result. The device for automatically analyzing the prostatic fluid comprises the microscope, the image acquisition unit and the image analysis unit, and the image acquisition unit is used for acquiring the initial image formed by the prostatic fluid glass slide under the microscope and transmitting the image to the image analysis unit; and the image analysis unit is used foranalyzing the initial image and forming the recognition result. The method and the device for automatically analyzing the prostatic fluid can avoid manual analysis errors and improve the measuring precision of every detection index of the prostatic fluid.

The invention discloses a cross-modal fusion disease analysis system and device, and a storage medium. The system comprises a data acquisition module used for acquiring a plurality of prostatic fluid appearance image samples, corresponding prostatic fluid routine detection data and accompanying symptom feature information; a preprocessing module, which is used for performing image feature extraction on the prostatic fluid appearance image sample and preprocessing corresponding prostatic fluid conventional detection data and accompanying symptom feature information; a feature fusion module, which is used for fusing the three features after preprocessing and performing normalization processing to form a set of prostatic fluid medical biological features and corresponding diseases; a relationship mining module, which is used for extracting association rules between the prostatic fluid medical biological features and the corresponding diseases by utilizing an association rule mining algorithm; and a disease analysis module, which is used for performing disease analysis based on the association rule of the relationship mining module. According to the invention, automatic disease cognition and analysis based on cross-modal fusion are realized.

The invention belongs to the technical field of medical auxiliary examination and diagnosis and treatment auxiliary facilities. A prostate disease diagnosis auxiliary device comprises a bed body used for supporting the upper part of the body; the leg supporting device comprises a pair of supporting plates, a first driving mechanism and a second driving mechanism, the pair of supporting plates are used for bearing knees, the first driving mechanism is used for driving the supporting plates to ascend and descend, the second driving mechanism is used for adjusting the horizontal included angle between the pair of supporting plates, and limiting mechanisms for limiting shanks arranged on the supporting plates are arranged on the supporting plates; the sample receiving device comprises a sampling test tube, a supporting mechanism and a sample receiving mechanism, and when the sample receiving device works, the supporting mechanism is used for limiting the genital organ so that the head of the genital organ of the patient can be aligned with and make contact with a test tube opening of the sampling test tube on the sample receiving mechanism. According to the device, the body position of a patient can be automatically adjusted during liquid taking, the liquid taking efficiency is improved, effective support can be provided for the patient, and the sample receiving device is used for replacing a medical worker to hold a test tube or a glass sheet by hand to collect prostatic liquid discharged by genitals.

The invention belongs to the technical field of medicine formulas, and particularly relates to a hydrogen molecule composition for treating prostatitis. The hydrogen molecule composition is a composition synthesized from a first gas hydrogen molecule, deuterium-depleted water and several medical medicine components. According to the hydrogen molecule composition, hydrogen molecules, the deuterium-depleted water and various medical medicines are combined in a matching mode, the effects of resisting oxidation and inflammation and removing malignant free radicals in living bodies are achieved on glands; through atomization administration of the hydrogen molecule composition on prostatitis patients, the dosage can be accurately controlled according to different individuals, and gas can be directly sprayed to the periphery of a focus target spot part, is suitable for being directly absorbed by a human body, is small in dosage, can improve and accelerate curative effects, improve prostate microcirculation disturbance, dredge blocked glandular tubes, and is beneficial to excretion of inflammatory prostatic fluid, elimination of inflammatory products and bacteria and regeneration and repair of tissue, so that the normal function is recovered, and the health of male prostate is effectively conditioned.

The invention discloses radix puerariae and dried orange peel capsules. The radix puerariae and dried orange peel capsules consist of the following raw materials in parts by weight: 4-13 parts of pangolin scales, 2-6 parts of rhizoma curcumae, 2-6 parts of hirudo, 5-15 parts of radix puerariae, 2-8 parts of radix scutellariae, 2-15 parts of dried orange peel, 2-16 parts of semen hoveniae, 3-20 parts of concha ostreae, 0.5-5 parts of talcum and 0.5-6 parts of cortex cinnamomi. With the application of the radix puerariae and dried orange peel capsules disclosed by the invention, the weight and volume of prostate glands can be reduced and a lecithin drop density in prostatic fluid can be recovered; therefore, the radix puerariae and dried orange peel capsules are excellent in effect on resisting benign prostatic hyperplasia. The radix puerariae and dried orange peel capsules disclosed by the invention can prevent the development of diseases; and in addition, the radix puerariae and dried orange peel capsules can relieve symptoms in patients.

The invention discloses radix puerariae and dried orange peel capsules. The radix puerariae and dried orange peel capsules consist of the following raw materials in parts by weight: 4-13 parts of pangolin scales, 2-6 parts of rhizoma curcumae, 2-6 parts of hirudo, 5-15 parts of radix puerariae, 2-8 parts of radix scutellariae, 2-15 parts of dried orange peel, 2-16 parts of semen hoveniae, 3-20 parts of concha ostreae, 0.5-5 parts of talcum and 0.5-6 parts of cortex cinnamomi. With the application of the radix puerariae and dried orange peel capsules disclosed by the invention, the weight and volume of prostate glands can be reduced and a lecithin drop density in prostatic fluid can be recovered; therefore, the radix puerariae and dried orange peel capsules are excellent in effect on resisting benign prostatic hyperplasia. The radix puerariae and dried orange peel capsules disclosed by the invention can prevent the development of diseases; and in addition, the radix puerariae and dried orange peel capsules can relieve symptoms in patients.

The invention discloses a device for obtaining prostatic fluid, which comprises a base plate, a plurality of petal claws are arranged on the periphery of the substrate, the petal claws are hinged to the base plate, and a vibrator is arranged in the area surrounded by the multiple petal claws. The claw is connected to the vibrator by a spring. The prostatic fluid acquisition device with this structure can not only improve the acquisition efficiency of the prostatic fluid, but also reduce the labor intensity of medical staff.

The invention discloses a prostatic fluid obtaining instrument, and belongs to the technical field of diagnosis. The prostatic fluid obtaining instrument comprises a vibrator, wherein the shape of the vibrator is matched with the shape of the bladder of a human body, one end of the vibrator is a vibration end used for carrying out massaging stimulation on the prostatic region of the human body, the other end of the vibrator is an operating end used for realizing the operation for obtaining prostatic fluid, the end part of the vibration end is a ball-shaped detection part, a probe capable of realizing 360-degree imaging is arranged inside the detection part, the operating end is provided with a holding part, and a driving power supply is arranged in the vibrator. The prostatic fluid obtaining instrument is provided with the electric vibrator, in addition, the vibration section is provided with a plurality of bulges, the stimulation effect on the prostatic region of the human body can be improved, the prostatic fluid obtaining effect is improved, the electric mode is used for replacing a manual mode, and medical personnel can be liberated from painful finger pressing work; in addition, the prostatic fluid obtaining instrument has the advantages that the structure is simple, the operation is convenient, safety and reliability are realized, and the obtaining efficiency is high.

The invention discloses a prostate therapeutic apparatus. The prostate therapeutic apparatus comprises a massaging head for massaging the prostate, a connecting handle connected with the massaging head and a driving device for driving the massaging head, and further comprises a collecting container used for collecting prostatic fluid and connected at the other end of the connecting handle. An opening is formed in the surface of the massaging head, and the connecting handle comprises a channel used for leading the prostatic fluid into the collecting container. The relative positions of the connecting handle and the massaging head can be adjusted, and the connecting handle is provided with an opening which corresponds to the opening in the surface of the massaging head; when the opening in the connecting handle and the opening of the massaging head are in the same position, the prostatic fluid can be led out through the openings, and when the opening of the connecting handle and the opening of the massaging head are not in the same position, the prostatic fluid cannot pass through the openings.

The present invention provides a method for detecting the free hemoglobin in a prostatic fluid, comprising: obtaining prostatic fluid seepage; processing the seepage with a trihydroxymethyl aminomethane-hydrochloric acid buffer solution with a PH of 7.4; and then enabling the seepage to react with a color reagent, comparing with a shade guide, and recording detection results. The method is simple and practical, is low in cost, and can rapidly screen out samples containing no hemoglobin, samples containing hemoglobin, and samples probably containing hemoglobin in cervical seepage, so as to make preparations for further screening. Meanwhile, the present invention also relates to a detection kit for detecting prostatic fluid seepage.

The invention provides a method and a device for automatically analyzing a prostatic fluid. The method for automatically analyzing the prostatic fluid comprises the following steps: an image acquisition unit acquires an initial image formed by a prostatic fluid glass slide under a microscope and transmits the image to an image analysis unit; and the image analysis unit analyzes the initial image and forms a recognition result. The device for automatically analyzing the prostatic fluid comprises the microscope, the image acquisition unit and the image analysis unit, and the image acquisition unit is used for acquiring the initial image formed by the prostatic fluid glass slide under the microscope and transmitting the image to the image analysis unit; and the image analysis unit is used foranalyzing the initial image and forming the recognition result. The method and the device for automatically analyzing the prostatic fluid can avoid manual analysis errors and improve the measuring precision of every detection index of the prostatic fluid.

The invention discloses a balloon-type prostate treating and prostatic fluid obtaining device in the rectum, and belongs to the technical field of medical instruments. A rod body is of a hollow structure with an opening in one end, the side wall of the rod body is provided with a notch, a heating mechanism comprises a balloon arranged in the rod body, and the opening end of the balloon and the opening end of the rod body are hermetically fixed; the device further comprises a heating water tank and a conversion shell of a hollow structure, the opening end of the rod body is fixedly connected with the conversion shell, an inlet of the heating water tank is connected with a water storage tank, an outlet of the heating water tank and the opening end of the balloon are communicated with the interior of the conversion shell, a drainage water pump is connected to the conversion shell, and with the assistance of water filling the balloon from the heating water tank, the balloon expands to makethe free end of the balloon popped up from the notch of the rod body and in tight contact with the prostate. The heating effect is better, and the safety is higher. When prostatic fluid is obtained,a doctor does not need to carry out manual operation, the device is friendlier to users, and the balloon can be in accurate contact with the prostate to reduce the discomfort of a patient.

Disclosed are methods to induce dislodgement of target prostatic cells from the prostate organ, collecting said cells, and subsequently examining the cell population. Such methods comprise the administration of an agent that facilitates the dislodgement of the target cells from within the prostate, which then migrate into the urethra. Exemplary agents include 5 alpha-reductase inhibitors. The cells induced to pass into the urethra are then collected non-invasively, such as through urine or semen samples. Such collection is further strategically calculated relative the administration of the agent so as to maximize the sample collection of the target cells of interest. The exfoliated prostatic epithelial cells are subsequently utilized for purposes such as detecting prostate cancer, predicting / measuring prostate tumor susceptibility to drug regimes, active surveillance of patients whose prostate biopsy results are negative, but continue to exhibit symptoms consistent with prostate cancer, and identifying false positive results associated with biomarker assays.