20 results about "Penile Diseases" patented technology

The present application relates to the technical field of stem cell medicine, in particular to a mesenchymal stem cell composition for treating prostate diseases and a preparation method and application thereof. The mesenchymal stem cell composition for treating prostate diseases comprises mesenchymal stem cells treated by low oxygen and an anti-inflammatory peptide WYPWMKKHHRRRRRRRRR. The prostate diseases are selected from prostatitis, prostate calcification, sexual function improvement, frequent urination and urgency, etc. The mesenchymal stem cell composition can significantly improve the symptoms of prostate diseases, and the curative effect is remarkable.

The invention relates to the technical field of uterus image segmentation, in particular to a woman uterus disease auxiliary diagnosis and evaluation system based on magnetic resonance imaging. After a uterus image of a patient is obtained and a uterine cavity area is positioned, clustering clusters are divided according to pixel gray values by using a clustering algorithm to correspond to different uterus areas. And generating an endometrial region descriptor and screening out an endometrial region by combining the pixel number distribution of each region, the gray features and the shape difference between the endometrial region descriptor and the uterine cavity. Performing gray scale segmentation on the region to extract a high-signal region, and calculating an internal descriptor according to internal edge distribution and morphological characteristics of the high-signal region; meanwhile, an external descriptor is generated based on edge pixel neighborhood gray scale difference. And finally fusing internal and external descriptors to realize auxiliary diagnosis of uterine diseases. According to the method, the uterus image with obvious uterine cancer staging development tendency can be screened out, and a more accurate diagnosis effect is provided for related personnel.

A male sexual function therapeutic instrument belongs to the technical field of male sexual function disease health care instruments. The male sexual function therapeutic instrument solves the problems that an existing male sexual function therapeutic instrument is complex in structure and operation and simple in function. A face shell and a bottom shell are connected in a matched mode to form a cavity, a water tank, an air pump, a water pump and a main control board are arranged in the cavity, the water pump is connected with the water tank in a matched mode, the main control board, the air pump and the water pump are connected with a treatment head socket in a matched mode, and an interface of the treatment head socket penetrates through the face shell and the bottom shell to be arranged outside the face shell and the bottom shell. One end of the treatment head assembly is cooperatively connected with the treatment head socket, the treatment head assembly is connected with a treatment cylinder, the water tank is connected with the treatment head assembly through a water pump, and the main control board is provided with an electromagnetic valve and a DC socket. The male sexual function therapeutic apparatus is simple in structure and has more practical functions.

The present invention addresses the problem of providing a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide with high safety and high yield. The present invention relates to a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide or a salt thereof via 3-methyl-1, 2, 4-thiadiazole-5-carboxamide or a salt thereof without the use of toxic carbon monoxide, and more particularly, to a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide or a salt thereof via 3-methyl-1, 2, 4-thiadiazole-5-carboxamide or a salt thereof. According to the present invention, it is possible to provide a safe and high-yield method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide, which is an important synthetic intermediate for non-azonetin, which is useful as a drug for the treatment of sex hormone-dependent diseases.

The invention further relates to compounds, pharmaceutical compositions and methods for treating a subject for sexual function, such as sexual disorder or sexual dysfunction (SD), for inducing subject weight loss, for effectuating weight maintenance by a subject, whether or not the weight maintenance is used alone or in combination with a subject's weight loss, and / or for improving a subject's subjective state of well-being, self-esteem and / or self-confidence. Examples of SD contemplated by the present invention include but are not limited to female sexual disorder (FSD), female sexual arousal disorder (FSAD), female sexual interest / arousal disorder (FSIAD), female hypoactive sexual desire disorder (HSDD), female orgasmic disorder (FOD), female sexual pain disorder (FSPD), sexual interest arousal disorder (SIAD), male sexual disorder (MSD), male hypoactive sexual desire disorder (MSHDD), erectile dysfunction (ED), Pyronine's disease (PD), male premature ejaculation (MPE), male delayed ejaculation (MDE), male decreased libido (MDL), male dry orgasm (MDO).

The present invention refers to a biomass of T. chuii and a pharmaceutical composition comprising a biomass of T. chuii for use in the treatment of infertility in a male subject. It also refers to a method for increasing the quality of the semen of a male subject having normozoospermia, not having hypospermia and not having a disorder characterized by a high percentage of sperm DNA fragmentation (SDF), that comprises the administration of a biomass of T. chuii.

Embodiments of the present invention provide GYN pathology simulation models for surgical training. These models are energy-compatible models emulating the tissue-based diseases of the female reproductive system to allow the surgical trainees and surgeons to practice advanced OB / GYN surgical skills. One simulated GYN model includes an electrically conductive elongated tube encapsulating a mass of non-conductive material. The elongated tube having a sidewall with an inner surface and outer surface extending between a proximal end and distal end. The sidewall is configured to have a cavity with a specific volume to yield an external protuberance when filled with the mass of non-conductive material. Another simulated GYN model includes a fluid-filled cystic body encapsulated within an electrically conductive bulbous hollow structure. The fluid-filled cystic body is selectively adhered to the bulbous hollow structure in at least one or more regions, thereby creating a plane for a combination of blunt and sharp dissection.

The utility model provides a multi-head vibration massage instrument for male genital organ health care, which comprises a shell, a double-shaft driving motor is arranged in the shell, five massage heads are arranged on the shell, the five massage heads are arranged in an isosceles triangle shape, and the massage heads are connected with the double-shaft driving motor. The massage heads located at the vertex angle position of the isosceles triangle are obliquely arranged and connected with the double-shaft driving motor through a crank connecting rod mechanism, and the massage heads located at the waist and the base angle position of the isosceles triangle are connected with the double-shaft driving motor through an eccentric swing mechanism. The prostate therapeutic instrument is compact in structure, the five massage heads are arranged to conduct vibration massage on the perineum point, the testis root Yinlian point and the penis root respectively, male diseases such as chronic prostatitis are relieved, a medical prostate therapeutic instrument and a household prostate therapeutic instrument are effectively replaced, operation is convenient, use is safe, and the market blank at the present stage is filled up.

The invention discloses an oral intersection protective film for improving sexual interest and preventing sexually transmitted diseases and a preparation method, and relates to the technical field of medical instruments, the preparation method comprises the following steps: S1, preparation of a base material film: preparing a base material layer film with the thickness of 10-50 microns by adopting waterborne polyurethane resin through a tape casting method or a film blowing method; s2, constructing a composite functional layer: uniformly dispersing the antibacterial and antiviral agent in a waterborne polyurethane solution, coating one surface of the base material layer with a precise coating device to form the composite functional layer, and drying and curing at 50-70 DEG C. The composite functional layer is arranged and contains an effective amount of broad-spectrum antibacterial and antiviral agent, so that the antibacterial and antiviral composite material is obtained. The infection risk of sexually transmitted diseases can be remarkably reduced, and the use safety is improved. Meanwhile, a microencapsulated and embedded food-grade flavoring agent and a warm and hot sensing preparation are adopted in the sensory enhancement layer, so that a pleasant flavor can be released and a comfortable warm and hot sense can be generated in the use process, and sexual interest experience is effectively improved.

The invention discloses a Y chromosome detection fluorescent probe kit based on SRY and TSPY1 double genes and an application method, and belongs to the technical field of molecular biological detection. The kit comprises a primer pair and a fluorescence labeling probe which are used for specifically amplifying and detecting an SRY gene and a TSPY1 gene on a Y chromosome, and a primer pair and a fluorescence labeling probe of a GAPDH gene serving as an internal reference. Two Y chromosome functional genes which are crucial to male gonad development are synchronously detected in a reaction system through a multiplex fluorescent PCR technology. The kit is mainly used for (1) auxiliary diagnosis of Y chromosome linked genetic diseases; (2) evaluating the integrity of the key gene region of the Y chromosome of the fetus, and providing non-invasive prenatal risk evaluation for sexual development related diseases (such as gonadal insufficiency); and (3) the kit is used as an auxiliary screening tool for male infertility factors. Through double-site detection, the accuracy and reliability of detection are effectively improved, and the limitation of single-site detection is avoided.

The invention belongs to the field of ovum collection auxiliary equipment in the reproductive department, and provides an ovary fixing device for transabdominal ovum collection, which is mainly suitable for transabdominal ovum collection operation of infertility patients who have difficulty in transvaginal ovum collection such as complicated uterine diseases and need laparotomy, and comprises an arc-shaped first enclosure piece and an arc-shaped second enclosure piece, first magnetic strips are arranged at the left end and the right end of the first enclosure piece, and second magnetic strips capable of being attracted with the first magnetic strips are arranged at the left end and the right end of the second enclosure piece. The first enclosure piece and the second enclosure piece are attracted through the first magnetic strip and the second magnetic strip and define an ovary fixing area which is open in the upper portion and the lower portion and is in an inverted circular truncated cone shape. The ovary fixing device for transabdominal ovum collection is simple in structure and convenient to use, the ovary can be fixed in the formed ovary fixing area, ovum collection inconvenience caused by back-and-forth sliding of the ovary is avoided, the accuracy and success rate of the ovum collection process are improved, the time of the ovum collection process is shortened, the operation efficiency and the ovum collection rate are improved, and the ovum collection efficiency is improved. Meanwhile, the effect of protecting the ovary is achieved.

1. Name of the product in this design: Handheld Laser Therapy Device. 2. Intended use of this design: for the treatment of skin diseases such as psoriasis, vitiligo, and eczema. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key features: the front view.

The invention belongs to the field of medicines for treating male infertility diseases, and discloses application of 12-ketolithocholic acid (12-keto-LCA) in the aspect of improving sperm quality decline, namely application of 12-keto-LCA in preparation of medicines for improving sperm quality decline. The invention provides a new application of 12-keto-LCA, reveals for the first time that 12-keto-LCA can support the spermatogenesis process, especially can improve the reproductive function of obese males, realizes the effects of improving testosterone secretion, repairing the spermatogenic function, improving the sperm quality and embryonic developmental ability and the like, and improves the condition that the sperm quality of mammals is reduced. The 12-keto-LCA can effectively relieve dyszoospermia of males, especially relieve damage of obesity to the reproductive function of males, and a new way is provided for developing drugs for improving the reproductive function of obese males.

Disclosed herein is a device for facilitating treatment for anorectal and pelvic floor disorders of users using biofeedback therapy. Accordingly, the device may include a body extending between a top end and a bottom end. Further, the device may include a balloon mounted on the top end portion of the body. Further, the device may include a plurality of sensors comprising at least one first sensor, at least one second sensor, and at least one third sensor. Further, the device may include a processing device communicatively coupled with the plurality of sensors. Further, the processing device may be configured for analyzing final first balloon data, first sensor data, second sensor data, and third sensor data, determining an anorectal anatomical change, and generating a dynamic visual representation and a static visual representation. Further, the device may include a communication device configured for transmitting the dynamic visual representation to an output device.

The present invention aims to provide a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide safely and in high yield. The present invention relates to a method for producing 3-methyl-1,2,4-thiadiazole-5-carboxamide or a salt thereof without using toxic carbon monoxide gas. According to the present invention, a safe and high-yielding production method of 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide, which is an important synthetic intermediate 21 for fezolinetant useful as a medicament for the treatment of sex hormone-dependent diseases, can be provided.

A laser hand tool for treating reproductive disorder disease, comprising a guide cylinder, an optical component and a treatment component. The guide cylinder comprises a body, a guide end, a connecting end and a treatment opening, the connecting end is provided with a connecting opening, and the treatment opening is arranged on the side wall of the body, so that the two sides of the side wall are communicated. The optical component comprises a plane light-transmitting mirror and a concave mirror, the plane light-transmitting mirror is arranged at the treatment opening, and the concave mirror is arranged to project the received light towards the plane light-transmitting mirror. The treatment component comprises a connecting seat, a first guide tube and a second guide tube, the first guide tube is arranged in the body and fixed to the connecting seat at one end, and the second guide tube is arranged in the body and fixed to the connecting seat at one end. The laser hand tool realizes the introduction of laser light into the uterus, expands the treatment area of the uterine cavity wall, and realizes the laser treatment of reproductive disorder disease.

The invention relates to an anatomical model comprising, at least on the inner surface (15, 16) of its wall, a polychrome representation (32) of a microvascularisation network produced by additive manufacturing. This polychrome representation may advantageously include a pattern (35) simulating a disease resulting in a localised change in the appearance of the microvascularisation network. The anatomical model is, for example, the reproduction of a bladder (6), a urethra (5), two kidneys (8) and two ureters (7).

The invention provides application of dibutyl phthalate in construction of a testis injury model. Animal experiments discover that dibutyl phthalate can stably construct a model of damaged testicular tissues of mice at the early stage of adolescence, and can destroy normal growth and development of the testis of the mice, destroy the testosterone secretion function of the testis of the mice, and destroy the blood testosterone barrier and the normal structure of the testicular tissues of the mice. The invention develops new application of dibutyl phthalate, provides a new choice for constructing a mouse testis injury model at the early stage of adolescence, and is beneficial to related research of reproductive diseases.

According to the application of the flibaserin and the derivative thereof in preparing the medicine for resisting the prostate diseases, the flibaserin serves as a treatment medicine, proliferation of prostate cancer cells can be inhibited, growth of in-vivo tumors can be inhibited, on the premise of low toxic and side effects, the progress of castration-resistant prostate cancer can be relieved, and the prostate diseases can be prevented. Prostatic hyperplasia and prostatic hyperplasia are reduced; the method plays an important role in prolonging the lifetime of a patient and slowing down proliferation, migration and invasion of diseases.

The invention discloses application of OPA1 in preparation of a product for treating and / or preventing traumatic osteoarthritis, and belongs to the technical field of biological medicines. The conventional means are difficult to treat and prevent traumatic osteoarthritis from a molecular level and cannot block cartilage fibrosis and disease progression. The OPA1 is used for preparing related products, chondrocyte mitochondrial functions can be successfully repaired, cartilage fibrosis can be inhibited, treatment and postoperative prevention of traumatic osteoarthritis can be realized, and the OPA1 is high in targeting and high in safety.