40 results about "Penile Diseases" patented technology

The present application relates to the technical field of stem cell medicine, in particular to a mesenchymal stem cell composition for treating prostate diseases and a preparation method and application thereof. The mesenchymal stem cell composition for treating prostate diseases comprises mesenchymal stem cells treated by low oxygen and an anti-inflammatory peptide WYPWMKKHHRRRRRRRRR. The prostate diseases are selected from prostatitis, prostate calcification, sexual function improvement, frequent urination and urgency, etc. The mesenchymal stem cell composition can significantly improve the symptoms of prostate diseases, and the curative effect is remarkable.

The present disclosure provides industrially scalable methods of making (Z)-endoxifen or a salt thereof, crystalline forms of endoxifin, and compositions comprising them. The present disclosure also provides methods for treating hormone-dependent breast and hormone-dependent reproductive tract disorders.

The invention relates to the technical field of uterus image segmentation, in particular to a woman uterus disease auxiliary diagnosis and evaluation system based on magnetic resonance imaging. After a uterus image of a patient is obtained and a uterine cavity area is positioned, clustering clusters are divided according to pixel gray values by using a clustering algorithm to correspond to different uterus areas. And generating an endometrial region descriptor and screening out an endometrial region by combining the pixel number distribution of each region, the gray features and the shape difference between the endometrial region descriptor and the uterine cavity. Performing gray scale segmentation on the region to extract a high-signal region, and calculating an internal descriptor according to internal edge distribution and morphological characteristics of the high-signal region; meanwhile, an external descriptor is generated based on edge pixel neighborhood gray scale difference. And finally fusing internal and external descriptors to realize auxiliary diagnosis of uterine diseases. According to the method, the uterus image with obvious uterine cancer staging development tendency can be screened out, and a more accurate diagnosis effect is provided for related personnel.

A male sexual function therapeutic instrument belongs to the technical field of male sexual function disease health care instruments. The male sexual function therapeutic instrument solves the problems that an existing male sexual function therapeutic instrument is complex in structure and operation and simple in function. A face shell and a bottom shell are connected in a matched mode to form a cavity, a water tank, an air pump, a water pump and a main control board are arranged in the cavity, the water pump is connected with the water tank in a matched mode, the main control board, the air pump and the water pump are connected with a treatment head socket in a matched mode, and an interface of the treatment head socket penetrates through the face shell and the bottom shell to be arranged outside the face shell and the bottom shell. One end of the treatment head assembly is cooperatively connected with the treatment head socket, the treatment head assembly is connected with a treatment cylinder, the water tank is connected with the treatment head assembly through a water pump, and the main control board is provided with an electromagnetic valve and a DC socket. The male sexual function therapeutic apparatus is simple in structure and has more practical functions.

The present invention addresses the problem of providing a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide with high safety and high yield. The present invention relates to a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide or a salt thereof via 3-methyl-1, 2, 4-thiadiazole-5-carboxamide or a salt thereof without the use of toxic carbon monoxide, and more particularly, to a method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide or a salt thereof via 3-methyl-1, 2, 4-thiadiazole-5-carboxamide or a salt thereof. According to the present invention, it is possible to provide a safe and high-yield method for producing 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide, which is an important synthetic intermediate for non-azonetin, which is useful as a drug for the treatment of sex hormone-dependent diseases.

1. The name of the product under this design: Condom. 2. Purpose of the product of this design: for contraception and prevention of sexually transmitted diseases. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the key design points: A-A section view. 5. The left view, right view and rear view of this design product are consistent with the main view, so the left view, right view and rear view are omitted.

The invention further relates to compounds, pharmaceutical compositions and methods for treating a subject for sexual function, such as sexual disorder or sexual dysfunction (SD), for inducing subject weight loss, for effectuating weight maintenance by a subject, whether or not the weight maintenance is used alone or in combination with a subject's weight loss, and / or for improving a subject's subjective state of well-being, self-esteem and / or self-confidence. Examples of SD contemplated by the present invention include but are not limited to female sexual disorder (FSD), female sexual arousal disorder (FSAD), female sexual interest / arousal disorder (FSIAD), female hypoactive sexual desire disorder (HSDD), female orgasmic disorder (FOD), female sexual pain disorder (FSPD), sexual interest arousal disorder (SIAD), male sexual disorder (MSD), male hypoactive sexual desire disorder (MSHDD), erectile dysfunction (ED), Pyronine's disease (PD), male premature ejaculation (MPE), male delayed ejaculation (MDE), male decreased libido (MDL), male dry orgasm (MDO).

This invention sets forth as a protective device for the lips of a person who may be exposed to sexually transmitted infections (STIs) or sexually transmitted diseases (STDs); acting as a barrier to protect against the transmission of such as a result of contact with potentially infected lips, genitals, anus, body parts, devices, or other during kissing, intimacy, intercourse, or other exposure, is inexpensive, easy to affix and can be carried conveniently. The invention may be used for mental and physical sexual health prevention and protection for the lips, as well as a fashionably trendy cosmetic cover for the lips, namely if symptoms of STIs such as herpes may exist, cold sores, acne, cleft lip, or other lip distortions, or to ease concerns, stereotypes, stigmas or uncomfortableness while in public or intimate settings, or for sanitary purposes, or as a party favor.

The present invention refers to a biomass of T. chuii and a pharmaceutical composition comprising a biomass of T. chuii for use in the treatment of infertility in a male subject. It also refers to a method for increasing the quality of the semen of a male subject having normozoospermia, not having hypospermia and not having a disorder characterized by a high percentage of sperm DNA fragmentation (SDF), that comprises the administration of a biomass of T. chuii.

This invention sets forth as a protective device for the lips of a person who may be exposed to sexually transmitted infections (STIs) or sexually transmitted diseases (STDs); acting as a barrier to protect against the transmission of such as a result of contact with potentially infected lips, genitals, anus, body parts, devices, or other during kissing, intimacy, intercourse, or other exposure, is inexpensive, easy to affix and can be carried conveniently. The invention may be used for mental and physical sexual health prevention and protection for the lips, as well as a fashionably trendy cosmetic cover for the lips, namely if symptoms of STIs such as herpes may exist, cold sores, acne, cleft lip, or other lip distortions, or to ease concerns, stereotypes, stigmas or uncomfortableness while in public or intimate settings, or for sanitary purposes, or as a party favor.

An implantable stimulation system having a stimulation unit coupled to a programmable controller, a stimulation circuit and an array of electrodes disposed on a pair of flexible paddles is provided for selectively stimulating at least one pelvic (e.g., cavernous) nerve. The implantable stimulation system may be programmed to run a first stimulation pulse sequence corresponding to a first mode for invoking a rapid erectile response for sexual performance and potential ejaculation, a second mode for invoking a rapid erectile response sufficient to facilitate a medical procedure such as application of a urinary catheter, a third nerve rehabilitation stimulation mode for rehabilitating neural transmission to thereby treat urinary incontinence and / or bowel dysfunction, and / or a fourth penile rehabilitation mode for reducing penile fibrosis. Methods of operating the system also are provided.

The invention discloses a seminal vesicle endoscope identification and positioning system based on a visual enhancement technology, and relates to the technical field of visual detection. A seminal vesicle endoscope is placed into a prostate small vesicle cavity through the urethra, and white light, fluorescent light and near-infrared images are synchronously collected through a three-channel CMOS sensor; extracting a fluorescence characteristic pattern, a scattering gradient characteristic pattern and a white light edge characteristic pattern, and fusing through an RGB thermodynamic diagram synthesis function; optimizing the learning rate of the convolutional neural network by using a genetic algorithm, training a weak region separation model to output a real-time weak region mask, screening a target spot in combination with a centroid, and marking the target spot; in the puncture stage, a tactile feedback needling instrument is integrated, resistance is monitored in real time, threshold response is set, drainage is verified through flushing, and the operation effect is confirmed through a double-black-hole wall breaking channel under a white light microscope; the multi-mode imaging fusion bottleneck is broken through, the weak area in the operation is accurately positioned, the puncture complication risk is reduced, the success rate of a single operation is improved, and a full-chain intelligent positioning navigation scheme is provided for minimally invasive treatment of seminal vesicle diseases.

Embodiments of the present invention provide GYN pathology simulation models for surgical training. These models are energy-compatible models emulating the tissue-based diseases of the female reproductive system to allow the surgical trainees and surgeons to practice advanced OB / GYN surgical skills. One simulated GYN model includes an electrically conductive elongated tube encapsulating a mass of non-conductive material. The elongated tube having a sidewall with an inner surface and outer surface extending between a proximal end and distal end. The sidewall is configured to have a cavity with a specific volume to yield an external protuberance when filled with the mass of non-conductive material. Another simulated GYN model includes a fluid-filled cystic body encapsulated within an electrically conductive bulbous hollow structure. The fluid-filled cystic body is selectively adhered to the bulbous hollow structure in at least one or more regions, thereby creating a plane for a combination of blunt and sharp dissection.

Disclosed herein are methods and apparatuses for a protective undergarment for protection against sexually transmitted diseases and infections during sexual activity, the protective undergarment having a central and cylindrical-shaped extension region with an opening to receive a penis of a user, and further configured to create a seal between the extension region and a condom placed over the penis of the user and the extension region. Other embodiments are described herein.

The utility model provides a multi-head vibration massage instrument for male genital organ health care, which comprises a shell, a double-shaft driving motor is arranged in the shell, five massage heads are arranged on the shell, the five massage heads are arranged in an isosceles triangle shape, and the massage heads are connected with the double-shaft driving motor. The massage heads located at the vertex angle position of the isosceles triangle are obliquely arranged and connected with the double-shaft driving motor through a crank connecting rod mechanism, and the massage heads located at the waist and the base angle position of the isosceles triangle are connected with the double-shaft driving motor through an eccentric swing mechanism. The prostate therapeutic instrument is compact in structure, the five massage heads are arranged to conduct vibration massage on the perineum point, the testis root Yinlian point and the penis root respectively, male diseases such as chronic prostatitis are relieved, a medical prostate therapeutic instrument and a household prostate therapeutic instrument are effectively replaced, operation is convenient, use is safe, and the market blank at the present stage is filled up.

The invention discloses an oral intersection protective film for improving sexual interest and preventing sexually transmitted diseases and a preparation method, and relates to the technical field of medical instruments, the preparation method comprises the following steps: S1, preparation of a base material film: preparing a base material layer film with the thickness of 10-50 microns by adopting waterborne polyurethane resin through a tape casting method or a film blowing method; s2, constructing a composite functional layer: uniformly dispersing the antibacterial and antiviral agent in a waterborne polyurethane solution, coating one surface of the base material layer with a precise coating device to form the composite functional layer, and drying and curing at 50-70 DEG C. The composite functional layer is arranged and contains an effective amount of broad-spectrum antibacterial and antiviral agent, so that the antibacterial and antiviral composite material is obtained. The infection risk of sexually transmitted diseases can be remarkably reduced, and the use safety is improved. Meanwhile, a microencapsulated and embedded food-grade flavoring agent and a warm and hot sensing preparation are adopted in the sensory enhancement layer, so that a pleasant flavor can be released and a comfortable warm and hot sense can be generated in the use process, and sexual interest experience is effectively improved.

The invention discloses a Y chromosome detection fluorescent probe kit based on SRY and TSPY1 double genes and an application method, and belongs to the technical field of molecular biological detection. The kit comprises a primer pair and a fluorescence labeling probe which are used for specifically amplifying and detecting an SRY gene and a TSPY1 gene on a Y chromosome, and a primer pair and a fluorescence labeling probe of a GAPDH gene serving as an internal reference. Two Y chromosome functional genes which are crucial to male gonad development are synchronously detected in a reaction system through a multiplex fluorescent PCR technology. The kit is mainly used for (1) auxiliary diagnosis of Y chromosome linked genetic diseases; (2) evaluating the integrity of the key gene region of the Y chromosome of the fetus, and providing non-invasive prenatal risk evaluation for sexual development related diseases (such as gonadal insufficiency); and (3) the kit is used as an auxiliary screening tool for male infertility factors. Through double-site detection, the accuracy and reliability of detection are effectively improved, and the limitation of single-site detection is avoided.

1. The name of this design product: USB flash drive (Commemorative Edition of the Integrated Prostate Disease Diagnosis and Treatment Center). 2. Purpose of this design product: used for quick access to data. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.

1. The name of the product of this design: Condom (D). 2. Purpose of the product of this design: for contraception and prevention of sexually transmitted diseases. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the key points of the design: A-A section view. 5. The left view, right view and rear view of this design product are consistent with the main view, so the left view, right view and rear view are omitted.

The invention belongs to the field of ovum collection auxiliary equipment in the reproductive department, and provides an ovary fixing device for transabdominal ovum collection, which is mainly suitable for transabdominal ovum collection operation of infertility patients who have difficulty in transvaginal ovum collection such as complicated uterine diseases and need laparotomy, and comprises an arc-shaped first enclosure piece and an arc-shaped second enclosure piece, first magnetic strips are arranged at the left end and the right end of the first enclosure piece, and second magnetic strips capable of being attracted with the first magnetic strips are arranged at the left end and the right end of the second enclosure piece. The first enclosure piece and the second enclosure piece are attracted through the first magnetic strip and the second magnetic strip and define an ovary fixing area which is open in the upper portion and the lower portion and is in an inverted circular truncated cone shape. The ovary fixing device for transabdominal ovum collection is simple in structure and convenient to use, the ovary can be fixed in the formed ovary fixing area, ovum collection inconvenience caused by back-and-forth sliding of the ovary is avoided, the accuracy and success rate of the ovum collection process are improved, the time of the ovum collection process is shortened, the operation efficiency and the ovum collection rate are improved, and the ovum collection efficiency is improved. Meanwhile, the effect of protecting the ovary is achieved.

A device dimensioned to temporarily retract the foreskin of an uncircumcised penis to allow for the healing of an infection or disease affecting the skin of the glans of the penis, external urethral orifice and foreskin; and / or to treat at least one of phimosis and paraphimosis. The device may be configured to stretch and constrict as needed without creating too much pressure as to cut off circulation, and / or include non-elastic and / or elastic synthetic material. Device may be available at different sizes to the patient to ensure the best fit. Device may perform other foreskin manipulation procedures, such as pulling it forward as opposed to retracting the foreskin. The use of such device.

The invention discloses a method for establishing an oligoasthenospermia animal model by utilizing flunarizine and application of the method, and belongs to the technical field of biological medicines. The method comprises the following steps: randomly grouping SPF-level experimental animals; injecting a flunarizine FNZ solution into the abdominal cavity continuously for 7 days; and verifying the oligospermia and asthenozoospermia indexes. In the animal model constructed by the method, the number and activity of sperms in the epididymis of an experimental animal are reduced, the mitochondrial membrane potential of the sperms is reduced due to FNZ, and ATP production is reduced, which indicates that the FNZ reduces the quality of the sperms. Therefore, the method for constructing the oligoasthenospermia model provides a proper animal model for researching male infertility diseases such as oligoasthenospermia and the like; the animal model can be used for animal experiments and new drug research and development for researching and developing occurrence and development mechanisms of male infertility diseases.

The utility model discloses a universal vagina muscle strength myoelectricity detection probe which comprises a probe body and an inflatable air bag arranged on the probe body in a sleeved mode, the probe body is of a hollow cylinder structure, and an inflation channel communicated with the inflatable air bag is arranged on the probe body. A muscle strength and myoelectricity detection contact is arranged at the top end of the inflatable air bag, a plurality of muscle strength and myoelectricity detection contacts are distributed on the circumference of the inflatable air bag in an array mode, the muscle strength and myoelectricity detection contacts are elastic air bags with pressure preset inside, pressure sensors are arranged in the elastic air bags, and flexible electrode plates are arranged on the outer surfaces of the elastic air bags. The whole part in contact with the vagina is of a full-flexible structure, different test sample groups can be adapted by controlling the inflation amount, the device has wide universality, meanwhile, the test accuracy of different testers can be guaranteed through the elastic air bags arranged in multiple channels, interference of abdominal pressure can be eliminated, and the test accuracy of the testers can be guaranteed. And a high-precision detection data basis is provided for clinical detection and treatment of pelvic floor diseases.

Compression trousers for a compressive treatment of edema or other diseases or injuries in a genital or pelvic region of a patient. The compression trousers include a compression element for exerting a compression on the genital region and / or the pelvic region of the patient, a pants part, detachable fastening elements and at least one waistband which is non-detachably fastened to or molded onto the compression element. The at least one waistband is configured to be fastened in a waist region or in an upper hip region of the patient by the detachable fastening elements. The compression element is permanently fastened to the pants part by a non-detachable fastening member and the pants part is fully enclosing at least the pelvic region of the patient, when the compression trousers are put on a patient.

1. Name of the product in this design: Handheld Laser Therapy Device. 2. Intended use of this design: for the treatment of skin diseases such as psoriasis, vitiligo, and eczema. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key features: the front view.

The invention relates to compression trousers, in particular for the compressive treatment of edema or other diseases or injuries in the genital or pelvic area of ​​a patient, comprising a compression element (1) for exerting compression on the genital and / or pelvic area of ​​the patient, a trouser part (2) and at least one waistband (3) permanently attached or molded to the compression element, wherein the at least one waistband (3) can be adjusted by means of fastening elements (4) to be placed in the area of ​​the waist or in the upper hip area of ​​the patient, and the trouser part (2) in the worn state fully encloses at least the pelvic area of ​​the patient.In order to enable individual and precise adaptation to the body shape, the setting of a desired, individually and precisely adjustable compression pressure both in the genital area and the groin area as well as in the hip area and comfortable wearing over a longer treatment period, it is provided that the compression element (1) is permanently attached to the trouser part (2).

The present disclosure relates to a protective device designed for the prevention of sexually transmitted diseases. The device includes a first portion made of a flexible material, forming a hollow tubular cavity with a closed end for enclosing the penis and an open end equipped with a first elastic ring. This ring is designed to snugly fit around the base of an erect penis. Extending from the first elastic ring, a second portion of the device is also made from a flexible material and is designed to form a larger cavity than the first. This second cavity, equipped with a second elastic ring, is intended to encircle and securely cover the base of the testicles and the penis shaft, thus providing comprehensive coverage of the male genitals.

The invention belongs to the field of medicines for treating male infertility diseases, and discloses application of 12-ketolithocholic acid (12-keto-LCA) in the aspect of improving sperm quality decline, namely application of 12-keto-LCA in preparation of medicines for improving sperm quality decline. The invention provides a new application of 12-keto-LCA, reveals for the first time that 12-keto-LCA can support the spermatogenesis process, especially can improve the reproductive function of obese males, realizes the effects of improving testosterone secretion, repairing the spermatogenic function, improving the sperm quality and embryonic developmental ability and the like, and improves the condition that the sperm quality of mammals is reduced. The 12-keto-LCA can effectively relieve dyszoospermia of males, especially relieve damage of obesity to the reproductive function of males, and a new way is provided for developing drugs for improving the reproductive function of obese males.

Disclosed herein is a device for facilitating treatment for anorectal and pelvic floor disorders of users using biofeedback therapy. Accordingly, the device may include a body extending between a top end and a bottom end. Further, the device may include a balloon mounted on the top end portion of the body. Further, the device may include a plurality of sensors comprising at least one first sensor, at least one second sensor, and at least one third sensor. Further, the device may include a processing device communicatively coupled with the plurality of sensors. Further, the processing device may be configured for analyzing final first balloon data, first sensor data, second sensor data, and third sensor data, determining an anorectal anatomical change, and generating a dynamic visual representation and a static visual representation. Further, the device may include a communication device configured for transmitting the dynamic visual representation to an output device.

The present invention relates to a composition comprising sestrin 2 for preventing or treating prostate diseases. Specifically, it has been identified that prostate diseases are inhibited by reducing the size, weight, or epithelial thickness of the prostate in an animal model in which prostate diseases are induced, and thus prostate diseases can be treated or prevented and urination disorders caused by prostate diseases can be alleviated.