Camel milk composite nutrition powder beneficial to bone health and preparation method of camel milk composite nutrition powder

Abstract

The invention belongs to the technical field of dairy product processing, and discloses camel milk composite nutrition powder beneficial to bone health, the camel milk composite nutrition powder is composed of the following raw materials by weight: 70%-75% of whole camel milk powder, 5%-15% of whey protein, 5%-20% of isomaltooligosacharide, 1%-10% of inulin, 0.02%-8% of milk mineral salt, 0.02%-5% of hydrolyzed yolk powder, and the balance water. The oral liquid is prepared from the following components in percentage by weight: 0.01%-0.5% of colostrum basic protein, 0.01%-1% of cartilage powder containing type II collagen, 0.01%-0.1% of N-acetylglucosamine, 0.01%-0.02% of sodium hyaluronate, 0.05%-5% of collagen peptide and 0.01%-1% of liquorice extract. According to the invention, a multi-dimensional health system is constructed by scientifically compounding a plurality of key components: milk mineral salt, colostrum basic protein and hydrolyzed egg yolk powder synergistically promote bone mineral density increase and bone metabolism balance; the II-type collagen cartilage powder, the N-acetylglucosamine and the sodium hyaluronate are combined to realize joint protection and skin repair; the six vitamins and the four minerals can accurately regulate and control the nutrition metabolism of the middle-aged and elderly people, especially can strengthen calcium absorption and oxidation resistance, and can significantly improve the bone health and improve the skin state.

Description

Technical Field

[0001] The present invention belongs to the technical field of dairy product processing, and particularly relates to a camel milk composite nutritional powder beneficial to bone health and a preparation method thereof. Background Art

[0002] The world's population is aging at an accelerating pace. As people age, the risks of bone and joint health problems (such as osteoporosis, rheumatoid arthritis, and osteoarthritis) gradually increase. With the increasing incidence of osteoporosis, osteoarthritis, etc., it is particularly important to protect bone health. In the food field, products with functions of increasing bone density, relieving joint pain, and alleviating osteoporosis have received more and more attention.

[0003] Currently, the functions of the products on bone health sold on the market are relatively single, focusing on either increasing bone density or one of the aspects of osteoarthritis. For products related to osteoarthritis, there are mainly chondroitin sulfate and glucosamine. The product types are mostly health foods or drugs, and the product dosage forms are mostly tablets and capsules. There are problems such as uneven product quality, difficult disintegration, low absorption rate, low bioavailability, and difficulty in being absorbed by the human body. At the same time, there are an endless stream of calcium supplement products, various drugs and functional foods for treating osteoporosis, but the nutrition, functions, and action pathways of these products are single, and they have no preventive effect on middle-aged and elderly people suffering from orthopedic diseases such as osteoporosis accompanied by osteoarthritis and bone pain, and cannot meet people's various needs. Existing calcium supplement products, various health foods and functional foods for treating and preventing osteoporosis or osteoarthritis emerge in an endless stream, but the functions and action pathways of these products are single, and they have no preventive effect on middle-aged and elderly people suffering from orthopedic diseases such as osteoporosis accompanied by osteoarthritis and osteoarthritis accompanied by osteoporosis, and cannot meet people's various needs. At the same time, in the formulations of many products, there are only the main functional ingredients, ignoring the imbalance in the daily requirements and intakes of comprehensive vitamins and minerals for middle-aged and elderly people. Therefore, it has important practical significance and broad market prospects to develop a functional camel milk powder that is nutritionally comprehensive, safe and effective, uses camel milk as the main raw material, can increase bone density, protect and lubricate bone joints, and at the same time enhance the body's immunity and supplement vitamins and minerals. Summary of the Invention

[0004] The purpose of the present invention is to provide a camel milk composite nutritional powder beneficial to bone health and a preparation method thereof, so as to solve the problems raised in the above background art.

[0005] To achieve the above object, the present invention provides the following technical solution: a camel milk composite nutritional powder helpful for bone health, which is composed of the following raw materials in parts by weight: 70%-75% of whole-fat camel milk powder, 5%-15% of whey protein, 5%-20% of isomaltooligosaccharide, 1%-10% of inulin, 0.02%-8% of milk mineral salts, 0.02%-5% of hydrolyzed egg yolk powder, 0.01%-0.5% of colostrum basic protein (CBP), 0.01%-1% of type II collagen cartilage powder, 0.01%-0.1% of N-acetylglucosamine, 0.01%-0.02% of sodium hyaluronate, 0.05%-5% of collagen peptide, 0.01%-1% of licorice extract, 0.01%-1% of pueraria extract, 0.1%-0.5% of compound vitamins, 0.5%-2.5% of compound minerals, and appropriate purified water.

[0006] Preferably, the nutrient contents in the compound vitamins are as follows: vitamin A 2402.40-3603.60 μg RE / g, vitamin D 49.30-73.95 μg / g, vitamin E 62.40-93.61 mg α-TE / g, vitamin B6 5.59-8.39 mg / g, vitamin C 196.00-294.00 mg / 100 g, folic acid 1596.00-2394.00 μg / 100 g;

[0007] The nutrient contents in the compound minerals are as follows: calcium 294.67-398.67 mg / g, iron 5.21-7.05 mg / g, zinc 1.70-2.30 mg / 100 g, selenium 14.93-22.40 μg / 100 g.

[0008] Preferably, the combined components of whole-fat camel milk powder and purified water in the raw materials of the camel milk composite nutritional powder can be replaced with the same proportion of fresh camel milk components.

[0009] Preferably, the preparation method steps of the camel milk composite nutritional powder include:

[0010] Step 1, the raw milk is pretreated by double-stage filtration, pasteurization and ice water cooling;

[0011] Step 2, the whole-fat camel milk powder, whey protein, isomaltooligosaccharide, inulin and water are mixed to form a basic milk phase, and the pretreated milk mineral salt solution, collagen peptide and antioxidant complex are added in gradients;

[0012] Step 3, the liquid material is subjected to secondary homogenization, ultra-high temperature instantaneous sterilization and multi-effect concentration;

[0013] Step 4, the concentrated milk is mixed with the microencapsulation wall material and then spray-dried, cooled in a fluidized bed and filled with nitrogen for packaging.

[0014] Preferably, the double-stage filtration in step 1 includes a 120-mesh double filter to remove mechanical impurities and a 15,000 rpm centrifugal milk purifier to remove micron-sized particles; the pasteurization parameter is 83-86°C / 15s, and the cooling adopts a spiral tube ice water system to reduce the temperature to 2-6°C.

[0015] Preferably, the gradient addition in step 2 comprises: adding milk mineral salt and hydrolyzed egg yolk powder to the basic milk phase after ultrasonically dispersing them in 45°C pure water at 40kHz for 15 minutes; and the antioxidant complex is formed by embedding licorice extract, kudzu root extract and β-cyclodextrin in a mass ratio of 1:0.6:2.

[0016] Preferably, in step 3, the secondary homogenization pressure is 20 MPa for the primary stage and 180 MPa for the secondary stage, 0.01% EDTA-2Na and 0.005% PMSF protease inhibitor are added before homogenization; the ultra-high temperature instantaneous sterilization parameter is 135°C / 5s, and the concentration at the concentrated end point is 18Be'.

[0017] Preferably, in step 4, the microencapsulation wall material is a 1:1 mixture of maltodextrin and whey protein, and the core material loading is 30%; the spray drying parameters include an inlet air temperature of 165°C, an exhaust air temperature of 85°C, and an atomization pressure of 18 MPa.

[0018] Preferably, the fluidized bed cooling is divided into two stages, the first stage cooling uses 15°C cold air to cool the powder to 40°C, and the second stage cooling uses 4°C cold air to finally cool the powder to 25°C; nitrogen is introduced throughout the process to maintain the oxygen content <0.5%.

[0019] Preferably, the colostrum basic protein (CBP) and type II collagen cartilage powder are premixed in a mass ratio of 10:1 and added in the latter stage of homogenization to avoid thermal shear damage; sodium hyaluronate and N-acetylglucosamine are compounded in a ratio of 1:3 to form a moisturizing network.

[0020] The beneficial effects of the present invention are as follows:

[0021] 1. This product builds a multi-dimensional bone health protection system by scientifically compounding milk mineral salts, colostrum alkaline protein (CBP) and hydrolyzed egg yolk powder. With its natural advantage of a calcium-phosphorus ratio of 1.8:1, milk mineral salts accurately simulate the composition of human bones, promote the synergistic absorption of calcium and phosphorus in the intestine, form an efficient calcium deposition mechanism, and significantly improve the basic value of bone density; CBP, as an innovative bone energy factor, establishes a positive cycle of "calcium absorption-bone storage" by targeted activation of osteoblast signaling pathways, and regulates osteoclast activity to achieve a dynamic balance of bone metabolism; hydrolyzed egg yolk powder activates osteoblast proliferation gene expression, stimulates the secretion of bone growth factors such as IGF-1, and while promoting calcium ossification deposition, enhances the strength of bone matrix fiber structure, inhibits osteoclast-mediated bone absorption, and forms a trinity bone metabolism regulation network.

[0022] 2. This product innovatively integrates type II collagen cartilage powder, N-acetylglucosamine and sodium hyaluronate to build a synergistic system for joint protection and skin repair. Type II collagen cartilage powder reconstructs the mechanical properties of articular cartilage by supplementing the specific matrix components of articular cartilage. The triple helix conformation in its molecular structure can specifically bind to joint synovial cells, inhibit the release of inflammatory factors, and significantly relieve the pain symptoms of osteoarthritis; N-acetylglucosamine, as the core building block of glycosaminoglycans, participates in the anabolism of cartilage extracellular matrix, repairs damaged proteoglycan networks, and maintains the elastic buffering function of articular cartilage; sodium hyaluronate, with its supramolecular hydrogel properties, forms a lubricating protective film in the joint cavity, reduces the friction coefficient of the joint, and at the same time, through its unique molecular sieve effect, realizes molecular-level filtration of synovial fluid and relieves joint swelling. In addition, its excellent moisturizing properties can form a moisture gradient in the skin stratum corneum, promote epidermal cell renewal, and significantly improve skin dryness and fine lines.

[0023] 3. This product builds a precise regulation system for the nutritional metabolism of middle-aged and elderly people through the precise proportion of 6 vitamins and 4 minerals. This formula especially strengthens the synergistic effect of vitamin D3 and calcium, and increases the bioavailability of calcium by more than 40% through the intestinal calcium absorption channel mediated by 1,25-dihydroxyvitamin D3, and forms a synergistic network of bone mineral metabolism with minerals such as magnesium and zinc; B vitamins participate in the regulation of energy metabolism and improve the body's conversion efficiency of nutrients; antioxidants such as vitamins C and E protect the membrane structure integrity of bone cells and skin cells by removing free radicals. At the same time, the collagen peptides in the formula form a skin nutrition matrix with sodium hyaluronate. The former binds to the skin fibroblast receptor through a triple helix structure to promote collagen synthesis, and the latter builds a skin natural moisturizing factor (NMF) library to achieve a dynamic balance of skin moisture content. Clinical verification shows that after 12 weeks of continuous use, the water content of the skin stratum corneum increases by 25% and the depth of facial wrinkles decreases by 18%. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 The present invention is a simplified diagram of the preparation process of the camel milk composite nutritional powder. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0026] like Figure 1As shown in the figure, an embodiment of the present invention provides a camel milk composite nutritional powder that is beneficial to bone health. The camel milk composite nutritional powder is composed of the following raw materials in parts by weight: 70%-75% of whole-fat camel milk powder, 5%-15% of whey protein, 5%-20% of isomaltooligosaccharide, 1%-10% of inulin, 0.02%-8% of milk mineral salts, 0.02%-5% of hydrolyzed egg yolk powder, 0.01%-0.5% of colostrum basic protein (CBP), 0.01%-1% of type II collagen cartilage powder, 0.01%-0.1% of N-acetylglucosamine, 0.01%-0.02% of sodium hyaluronate, 0.05%-5% of collagen peptide, 0.01%-1% of licorice extract, 0.01%-1% of pueraria root extract, 0.1%-0.5% of compound vitamins, 0.5%-2.5% of compound minerals, and an appropriate amount of purified water.

[0027] Among them, the nutrient contents in the compound vitamins are as follows: vitamin A 2402.40-3603.60 μg RE / g, vitamin D 49.30-73.95 μg / g, vitamin E 62.40-93.61 mg α-TE / g, vitamin B6 5.59-8.39 mg / g, vitamin C 196.00-294.00 mg / 100 g, folic acid 1596.00-2394.00 μg / 100 g;

[0028] The nutrient contents in the compound minerals are as follows: calcium 294.67-398.67 mg / g, iron 5.21-7.05 mg / g, zinc 1.70-2.30 mg / 100 g, selenium 14.93-22.40 μg / 100 g.

[0029] Among them, the combined components of whole-fat camel milk powder and purified water in the raw materials of the camel milk composite nutritional powder can be replaced with the same proportion of fresh camel milk components.

[0030] Among them, the preparation method steps of the camel milk composite nutritional powder include:

[0031] Step 1, the raw milk is pretreated by double-stage filtration, pasteurization, and ice water cooling;

[0032] Step 2, mix whole-fat camel milk powder, whey protein, isomaltooligosaccharide, inulin with water to form a basic milk phase, and gradually add the pretreated milk mineral salt solution, collagen peptide, and antioxidant complex;

[0033] Step 3, the liquid material is subjected to secondary homogenization, ultra-high temperature instantaneous sterilization, and multi-effect concentration;

[0034] Step 4, the concentrated milk is mixed with the microencapsulation wall material and then spray-dried, cooled in a fluidized bed, and filled with nitrogen for packaging.

[0035] Among them, the double-stage filtration in Step 1 includes a 120-mesh double filter to remove mechanical impurities and a 15,000-rpm centrifugal milk clarifier to remove micron-sized particles; the pasteurization parameters are 83 - 86 °C / 15 s, and cooling is carried out using a spiral tube ice water system to reduce the temperature to 2 - 6 °C.

[0036] Among them, the gradient addition in Step 2 includes: adding milk mineral salts and hydrolyzed egg yolk powder to the basic milk phase after ultrasonic dispersion in pure water at 45 °C for 15 min at 40 kHz; the antioxidant complex is formed by encapsulating licorice extract, pueraria root extract and β-cyclodextrin in a mass ratio of 1:0.6:2.

[0037] Among them, the secondary homogenization pressure in Step 3 is 20 MPa for the first stage and 180 MPa for the second stage, and 0.01% EDTA-2Na and 0.005% PMSF protease inhibitor are added before homogenization; the ultra-high temperature instantaneous sterilization parameters are 135 °C / 5 s, and the concentration end point concentration is 18 Be'.

[0038] Among them, the microencapsulation wall material in Step 4 is a compound of maltodextrin and whey protein in a ratio of 1:1, and the core material loading is 30%; the spray drying parameters include an inlet air temperature of 165 °C, an outlet air temperature of 85 °C, and an atomization pressure of 18 MPa.

[0039] Among them, the fluidized bed cooling is divided into two stages. The first stage of cooling uses 15 °C cold air to cool the powder to 40 °C, and the second stage of cooling uses 4 °C cold air to reach a final temperature of 25 °C; nitrogen is introduced throughout the process to maintain the oxygen content < 0.5%.

[0040] Among them, the colostrum basic protein (CBP) and type II collagen cartilage powder are premixed in a mass ratio of 10:1 and added in the latter stage of homogenization to avoid thermal shear damage; sodium hyaluronate and N-acetylglucosamine are compounded in a ratio of 1:3 to form a moisturizing network.

[0041] Example:

[0042] Raw material ratio:

[0043] Whole-fat camel milk powder 72%, whey protein 10%, isomaltooligosaccharide 15%, inulin 5%, milk mineral salts 3.5%, hydrolyzed egg yolk powder 2%, CBP 0.3%, type II collagen cartilage powder 0.5%, N-acetylglucosamine 0.05%, sodium hyaluronate 0.015%, collagen peptide 2%.

[0044] Preparation process:

[0045] Mix milk mineral salts and hydrolyzed egg yolk powder after ultrasonic dispersion at 45 °C with the camel milk base material preheated to 50 °C;

[0046] Add protease inhibitor during the homogenization stage, and the secondary homogenization pressure is 20 / 180 MPa;

[0047] After microencapsulation and spray drying, it is cooled to 25°C in a two-stage fluidized bed and then filled with nitrogen for packaging.

[0048] Effect verification:

[0049] Experiments on SD rats showed that the bone calcium content increased by 29% and the collagen deposition increased by 37%. After accelerated storage (40°C / RH75%) for 6 months, the retention rate of CBP activity was 91.2%, meeting the GB19644-2023 standard.

[0050] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or elements inherent to such process, method, article or device.

[0051] Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A camel milk composite nutritional powder that helps bone health, characterized by: The camel milk composite nutritional powder is composed of the following raw materials in parts by weight: 70%-75% whole camel milk powder, 5%-15% whey protein, 5%-20% isomaltooligosaccharide, 1%-10% inulin, 0.02%-8% milk mineral salt, 0.02%-5% hydrolyzed egg yolk powder, 0.01%-0.5% colostrum alkaline protein, 0.01%-1% cartilage powder containing type II collagen, 0.01%-0.1% N-acetylglucosamine, 0.01%-0.02% sodium hyaluronate, 0.05%-5% collagen peptide, 0.01%-1% liquorice extract, 0.01%-1% kudzu root extract, 0.1%-0.5% compound vitamins, 0.5%-2.5% compound minerals, and appropriate amount of purified water.

2. The camel milk composite nutritional powder that helps bone health according to claim 1, characterized in that: The content of each nutrient in the compound vitamin is as follows: vitamin A 2402.40-3603.60 μgRE / g, vitamin D 49.30-73.95 μg / g, vitamin E 62.40-93.61 mgα-TE / g, vitamin B 65.59-8.39 mg / g, vitamin C 196.00-294.00 mg / 100 g, folic acid 1596.00-2394.00 μg / 100 g; The contents of various nutrients in the compound minerals are as follows: calcium 294.67-398.67 mg / g, iron 5.21-7.05 mg / g, zinc 1.70-2.30 mg / 100 g, and selenium 14.93-22.40 μg / 100 g.

3. The camel milk composite nutritional powder that helps bone health according to claim 1, characterized in that: The whole camel milk powder and purified water components in the camel milk composite nutritional powder raw material can be replaced with fresh camel milk components in the same proportion.

4. A method for preparing a camel milk composite nutritional powder that is beneficial to bone health, characterized in that: The preparation method of the camel milk composite nutritional powder comprises the following steps: Step 1: The raw milk is pre-treated by double-stage filtration, pasteurization and ice water cooling; Step 2: Mix whole camel milk powder, whey protein, isomaltooligosaccharide, inulin and water to form a basic milk phase, and add pretreated milk mineral salt solution, collagen peptide and antioxidant complex in a gradient manner; Step 3: The feed liquid is subjected to secondary homogenization, ultra-high temperature instant sterilization and multi-effect concentration; Step 4: the concentrated milk is mixed with the microencapsulation wall material, spray-dried, fluidized bed cooled and nitrogen-filled for packaging.

5. The method for preparing a camel milk composite nutritional powder that is beneficial to bone health according to claim 4, characterized in that: The double-stage filtration in step 1 includes a 120-mesh double filter to remove mechanical impurities and a 15,000 rpm centrifugal milk purifier to remove micron-sized particles; the pasteurization parameter is 83-86° C. / 15s, and the cooling adopts a spiral tube ice water system to reduce the temperature to 2-6° C.

6. The method for preparing a camel milk composite nutritional powder that is beneficial to bone health according to claim 4, characterized in that: The gradient addition in step 2 includes: adding milk mineral salt and hydrolyzed egg yolk powder to the basic milk phase after ultrasonically dispersing them in 45° C. pure water at 40 kHz for 15 minutes; and the antioxidant complex is formed by embedding licorice extract, kudzu root extract and β-cyclodextrin in a mass ratio of 1:0.6:

2.

7. The method for preparing a camel milk composite nutritional powder that is beneficial to bone health according to claim 4, characterized in that: In the step 3, the secondary homogenization pressure is 20 MPa for the primary stage and 180 MPa for the secondary stage, 0.01% EDTA-2Na and 0.005% PMSF protease inhibitor are added before homogenization; the ultra-high temperature instantaneous sterilization parameter is 135°C / 5s, and the concentration at the concentrated end point is 18Be'.

8. The method for preparing a camel milk composite nutritional powder that is beneficial to bone health according to claim 4, characterized in that: In the step 4, the microencapsulation wall material is a 1:1 compound of maltodextrin and whey protein, and the core material loading is 30%; the spray drying parameters include an inlet air temperature of 165° C., an exhaust air temperature of 85° C., and an atomization pressure of 18 MPa.

9. The method for preparing a camel milk composite nutritional powder that is beneficial to bone health according to claim 4, characterized in that: The fluidized bed cooling is divided into two stages. The first stage cooling uses 15°C cold air to cool the powder to 40°C, and the second stage cooling uses 4°C cold air to finally cool the powder to 25°C. Nitrogen is introduced throughout the process to maintain the oxygen content <0.5%.

10. The method for preparing a camel milk composite nutritional powder that is beneficial to bone health according to claim 4, characterized in that: The colostrum basic protein and type II collagen cartilage powder are premixed in a mass ratio of 10:1 and added in the latter stage of homogenization to avoid thermal shear damage; sodium hyaluronate and N-acetylglucosamine are compounded in a ratio of 1:3 to form a moisturizing network.

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