The embodiments herein provide shape-transforming pharmaceutical compositions and modular kits for the treatment of soft and
hard tissue injuries, bone and joint defects,
tendon and
ligament repair, and surgical or organ exposures. The compositions comprise sterile, dry adsorbent
composite polymer particles that are hydrated in situ with a sterile liquid containing one or more pharmaceutical agents. Hydration causes the particles to aggregate and transform into a conforming, shape-retentive device that provides
extended coverage and sustained or controlled
drug release. Kits enable powders and liquids to be applied sequentially or simultaneously, allowing tailored therapy at the
point of care. Therapeutic agents may include
antimicrobial, anti-inflammatory, hemostatic, regenerative, or
analgesic compounds. These devices retain structure for extended durations, support customizable release
kinetics, and may serve as a temporary
implant to protect tissue while delivering
localized therapy. The invention provides a versatile platform for prolonged, modular
drug delivery across clinical and surgical settings.