71 results about "Ligament repair" patented technology

Surgical anchoring systems and methods are employed for the correction of bone deformities. The anchoring system and its associated instrument may be suitable for surgical repair of hallux valgus, tarsometatarsal sprains, ankle ligament reconstruction, spring ligament repair, knee ligament reinforcement, acromioclavicular sprains, coracoclavicular sprains, elbow ligament repair, wrist and hand ligamentous stabilization or similar conditions. The anchoring system may include a fixation system for anchoring two or more sections of bone or other body parts and a system for aligning of one section relative to another section.

Methods and devices for the repair of a ruptured ligament using a scaffold device are provided. Aspects of the invention, may include a scaffold attached by a suture to an anchor. In aspects of the invention, the anchor may be secured to a bone near or at the repair site.

Apparatus and methods for repairing damaged tendons or ligaments. Various repair apparatus include an elongate tensile member and a pair of anchor assemblies connected for movement along the tensile member on either side of a repair site, such as a tear or laceration. The anchor assemblies or structures may take many forms, and may include barbed, helical, and crimp-type anchors. In the preferred embodiments, at least one anchor structure is movable along the elongate tensile member to assist with adjusting a tendon segment to an appropriate repair position and the anchor structure or structures are then lockable onto the elongate tensile member to assist with affixing the tendon at the repair position. Tendon and / or ligament-to-bone repair apparatus and methods employ similar concepts.

A biocompatible ligament repair implant or scaffold device is provided for use in repairing a variety of ligament tissue injuries. The repair procedures may be conducted with ligament repair implants that contain a biological component that assists in healing or tissue repair. The biocompatible ligament repair implants include a biocompatible scaffold and particles of viable tissue derived from ligament tissue or tendon tissue, such that the tissue and the scaffold become associated. The particles of living tissue contain one or more viable cells that can migrate from the tissue and populate the scaffold.

Surgical anchoring systems and methods are employed for the correction of bone deformities. The anchoring system and its associated instrument may be suitable for surgical repair of hallux valgus, tarsometatarsal sprains, ankle ligament reconstruction, spring ligament repair, knee ligament reinforcement, acromioclavicular sprains, coracoclavicular sprains, elbow ligament repair, wrist and hand ligamentous stabilization or similar conditions. The anchoring system may include a fixation system for anchoring two or more sections of bone or other body parts and a system for aligning of one section relative to another section.

The disclosure describes implantable medical products, that include dry or partially hydrated biocompatible biostaples suitable for ligament repairs or replacements comprising collagen fibers that may be configured to expand in situ after implantation to frictionally engage a bone tunnel wall or bone sleeve to thereby affix the construct in the bone tunnel.

A method and apparatus for anatomical tissue repair, such as ligament repair and reconstruction with suture and / or graft passage, employing a pin with a suture passing mechanism. The suture passing mechanism may include a loop (for example, a wire loop or suture loop) securely attached to a pin (for example, a drill pin). The loop may be crimped onto the pin, or welded on the end of the drill pin (in place of the eyelet formed within the pin), to alleviate the difficulty in threading the eyelet and to lower the manufacturing cost of the pin. The suture passing mechanism may alternatively include a slotted suture eyelet (i.e., a longitudinal slot) provided at a proximal end of a pin, to allow suture loading from the side of the instrument.

Interposition and augmentation devices for tendon and ligament repair, including rotator cuff repair, have been developed as well as methods for their delivery using arthroscopic methods. The devices are preferably derived from biocompatible polyhydroxyalkanoates, and preferably from copolymers or homopolymers of 4-hydroxybutyrate. The devices may be delivered arthroscipiclly, and offer additional benefits such as support for the surgical repair, high initial strength, prolonged strength retention in vivo, flexibility, anti-adhesion properties, improved biocompatibility, an ability to remodel in vivo to healthy tissue, minimal risk for disease transmission or to potentiate infection, options for fixation including sufficiently high strength to prevent suture pull out or other detachment of the implanted device, eventual absorption eliminating future risk of foreign body reactions or interference with subsequent procedures, competitive cost, and long-term mechanical stability. The device are also particularly suitable for use in pediatric populations where their eventual absorption should not hinder growth.

A biocompatible ligament repair implant or scaffold device is provided for use in repairing a variety of ligament tissue injuries. The repair procedures may be conducted with ligament repair implants that contain a biological component that assists in healing or tissue repair. The biocompatible ligament repair implants include a biocompatible scaffold and particles of viable tissue derived from ligament tissue or tendon tissue, such that the tissue and the scaffold become associated. The particles of living tissue contain one or more viable cells that can migrate from the tissue and populate the scaffold.

Methods and device for treating or healing an injured tendon or ligament is disclosed. The device, a tendon and ligament repair sheet, has a porous layer and a denser layer, and optionally a therapeutic agent in the porous layer, the denser layer or both. The repair sheet is made from a resorbable or non-resorbable polymer. The repair sheet is securely attached to the injured tendon, ligament, muscle, or bone and has a suture pull out strength of at least 3N. If the injury involve severing of a ligament or tendon, one should place the severed ends in close proximity to each other and securely attach the repair sheet to both sides of the severed tendon or ligament at a distance from the injury so that the repair sheet remains securely attached to the tendon, ligament, muscle, or bone while the tissue is healing.

Devices and methods are provided for positioning and forming bone tunnels. In one embodiment, a surgical drill guide apparatus is provided. The apparatus can include a first guide member having a longitudinal passageway extending therethrough for aiming a first guide pin along a first path to form a first bone tunnel. The apparatus can also include a second guide member having a longitudinal passageway extending therethrough for aiming a second guide pin along a second path to form a second bone tunnel. The first and second guide members can extend at an angle relative to one another and they can be offset such that axes of the guide members do not intersect.

A technique and reconstruction system for ligament repair by determining the exact length of the graft to be secured within a first tunnel or socket (for example, a tibial tunnel) and a second tunnel or socket (for example, a femoral tunnel) for improved graft fixation. The exact length of the graft (soft tissue graft or BTB graft, for example) is determined with a measuring device, by measuring the length of a first socket in a first bone region (for example, a tibial socket), the length of a second socket in a second bone region (for example, a femoral socket), and the length of the intraarticular joint space between the two sockets in the two bone regions (for example, tibia and femur). The measuring device may consist of at least one flexible member (for example, suture) with at least one fixation device attached to the flexible member, the fixation device being either a sliding knot, a washer or a button.

The present invention relates to methods of treating pulmonary hypertension, facilitating joint fusion, facilitating tendon and ligament repair, reducing the occurrence of secondary fracture, treating avascular necrosis, facilitating cartilage repair, facilitating bone healing after limb transplantation, facilitating liver regeneration, facilitating wound healing, reducing the occurrence of gastric ulceration, treating hypertension, facilitating the growth of tooth enamel or finger or toe nails, treating glaucoma, treating ocular hypertension, and repairing damage caused by metastatic bone disease using an EP2 selective receptor agonist.

Suture delivered patches adapted for interposition, augmentation or repair devices for use in tendon and ligament repair, including rotator cuff repair, have been developed as well as methods for their delivery using suture guided arthroscopic methods. The repair patches may be provided from suitable biocompatible materials. The patches may be delivered using anchored sutures already in use during a surgical repair including, open, minimally invasive, endoscopic, and arthroscopic repair procedures. Additionally, fixation of the suture delivered repair patch is secured along with the normal suture securing workflow of the one or more sutures used to deliver the patch.

Techniques and reconstruction systems for ligament repair and fixation. A bone tendon graft is prepared by folding the bone block over a suspensory fixation device (for example, a knotless suture construct such as a knotless, adjustable, self-cinching suture loop / button construct, a suture, crosspin, or screw, etc.). A flexible strand is then used to suture the bone plug to the tendon so that the overall graft is shortened significantly and the suspensory fixation device is securely attached. The technique does not require passage of the suspensory fixation device through the bone block which makes the graft passage easier since the graft is pulled from the tip. The technique also allows shortening of the overall graft.

The invention discloses a fibroin-base artificial ligament repair material and a preparation method thereof. The ligament repair material comprises stents and laid-in yarns, wherein the stents are produced by carrying out biaxial laid-in warp knitting on natural mulberry silks; the laid-in yarns are regenerated silkworm silk fibroin filament yarns and regenerated silkworm silk nanofiber yarns. The preparation method specifically comprises the following steps of: (1) preparing biaxial laid-in warp knitting stent materials; (2) preparing regenerated silk fibroin filament yarns by utilizing a dry or wet spinning method; (3) preparing and dissloving a regenerated silk fibroin film, and preparing nanometer silk fibroin fiber yarns by utilizing an electrostatic spinning method; (4) taking a pure fibroin warp knitting material as a base material, taking the regenerated silkworm silk fibroin filament yarns and the nanometer silk fibroin fiber yarns as the laid-in yarns, weaving the base material and the laid-in yarns into the warp knitting stent material to obtain the artificial ligament repair material, and sewing two sides of a ligament material into a columnar structure. The preparation method is simple and efficient, and the artificial ligament repair material prepared by utilizing the preparation method has excellent compatibility, degradability and mechanical properties.

The present inventors disclose a method of promoting cartilage, bone or ligament repair or inducing cartilage tissue repair or regeneration, said method comprising increasing ZNF145 or a fragment, homologue, variant or derivative thereof in chondrogenic progenitor cells— For example, expression or activity in mesenchymal stem cells. The inventors also provide a chondrogenic progenitor cell, such as a mesenchymal stem cell (MSC), engineered to increase the expression or activity of ZNF145, or a fragment, homologue, variant or derivative thereof.

The invention provides a surgicval guide for use in ligament repair procedures, herein devices, systems, and methods are provided for ligament repair procedures, and can be used to establish a location and trajectory for forming a bone tunnel in bone. One exemplary embodiment of a surgical guide for using in a ligament repair procedure includes a guide arm and a carriage that can be selectively locked along the guide arm to define an angle of the bone tunnel. The guide arm also defines a location of a distal end of the bone tunnel. In some embodiments the carriage is configured to have a bullet side-loaded into it, and the bullet can be used to define a location of a proximal end of the bone tunnel. The present disclosure also provides for a gage that limits the distance a drill pin that drills the bone tunnel can travel. A variety of other, devices, systems, and methods are also provided.

Gage for Limiting Distal Travel of Drill Pin. Devices, systems, and methods are provided for ligament repair procedures, and can be used to establish a location and trajectory for forming a bone tunnel in bone. One exemplary embodiment of a surgical guide for using in a ligament repair procedure includes a guide arm and a carriage that can be selectively locked along the guide arm to define an angle of the bone tunnel. The guide arm also defines a location of a distal end of the bone tunnel. In some embodiments the carriage is configured to have a bullet side-loaded into it, and the bullet can be used to define a location of a proximal end of the bone tunnel. The present disclosure also provides for a gage that limits the distance a drill pin that drills the bone tunnel can travel. A variety of other, devices, systems, and methods are also provided.

The invention provides a device for reconstructing the coracoclavicular ligament. The device is composed of a bone fracture plate and high strength sutures, and the bone fracture plate is made of a titanium alloy material and provided with drill holes; the high strength sutures are made of a polyethylene terephthalate material; the sutures and the bone fracture plate are used in a matched mode; when the device is used, after the clavicle resets, the bone fracture plate is placed on the attachment segment of the clavicle coracoclavicular ligament, holes are drilled in two bones respectively, the high strength sutures sequentially penetrate through a hole channel in the bone fracture plate and holes drilled in the two bones to fix the clavicle onto a coracoids, then a flexible fixing rope is tightened till the clavicle and the coracoids recover to the normal distance, and finally knotting is conducted to conduct fixation. According to the device, in treatment of acromioclavicular dislocation, the problem of coracoclavicular ligament reconstruction is solved, and an internal fixator is removed without secondary surgery; the problem of ligament repair is solved, and pain of self-lifted ligament reconstruction is avoided; the device and an operation mode are minimally invasive, postoperative recovery is high in speed, pain of a patient is reduced, and the device is applicable to acromioclavicular dislocation caused by shoulder joint surgical treatment trauma and the like.

The present invention relates to methods of treating pulmonary hypertension, facilitating joint fusion, facilitating tendon and ligament repair, reducing the occurrence of secondary fracture, treating avascular necrosis, facilitating cartilage repair, facilitating bone healing after limb transplantation, facilitating liver regeneration, facilitating wound healing, reducing the occurrence of gastric ulceration, treating hypertension, facilitating the growth of tooth enamel or finger or toe nails, treating glaucoma, treating ocular hypertension, and repairing damage caused by metastatic bone disease using an EP2 selective receptor agonist.