34 results about "Mold infection" patented technology

The present invention relates to methods for treating and completely curing fungal, yeast, and / or mold infections in human subjects comprising topically administering to a human subject in need thereof an antifungal nanoemulsion composition.

The present invention relates to methods for treating and completely curing fungal, yeast and / or mold infections in human subjects comprising topically administering to a human subject in need thereof an antifungal nanoemulsion composition.

The present invention relates to methods for treating and completely curing fungal, yeast, and / or mold infections in human subjects comprising topically administering to a human subject in need thereof an antifungal nanoemulsion composition.

Provided herein are systems and methods associated therewith for killing molds and reducing other contaminating bioburden that may include bacteria and their spores, yeast, and viruses within various dwellings including homes, office buildings, institutions, and any other enclosed space in which humans reside, either temporarily or permanently. The technology of the present invention can be used to treat vehicles, airplanes, and ships. A process according to the invention includes the generation of a gaseous oxyhalogen species and distribution of the gaseous oxyhalogen species throughout a selected dwelling. It has been unexpectedly found that the concentration level of gaseous oxyhalogen species necessary to kill molds according to the inventive methods is far below that previously recognized in the art as being necessary for the killing of such molds. Thus, mold infestations may be killed in dwellings with minimal disruption to the usual business of the inhabitants. Further, fabrics such ad drapes and upholsteries contained within such dwellings may be carried out without causing any detrimental color changes to the fabrics.

Method and apparatus for using computer controlled, fiber-coupled laser delivery of treatment specific wavelength, intensity and duration of UV irradiation to control bacterial, fungal, viral and mold infections in bodily cavities, fluids and external applications. The method of treatment is focused on DNA breakdown beyond repair by natural DNA repair mechanisms of the pathogen, with less than damaging doses to tissues being treated, thus avoiding mutagenicity and carcinogenicity. The minimal intensity and duration and exposure area of any given surface of tissue to be treated is to be pre-determined by tissue and pathogen testing to optimize the therapeutic ratio. External applications include specifically Trichophyton Rubrum (toenail fungus) through the nail and Pseudomonas Aeruginosa infections in burns and elsewhere.

The present invention provides methods for detecting the presence of invasive pathogenic molds in biological samples that are based on amplification of mold nucleic acids. The methods may further comprise quantitating and real time detection of the invasive mold. The methods of the invention are highly specific and do not co-amplify human or other yeast nucleic acids. The methods of the invention are also extremely sensitive. Thus, methods for diagnosing infections caused by invasive mold are provided. The invention also provides kits for detection of invasive molds.

Isolated nucleic acids, kits and methods are disclosed for detecting, quantifying and / or identifying a fungal species in a sample or for diagnosing jejunal hemorrhage syndrome in a subject. The methods generally include amplifying a fungal nucleic acid sequence present in the sample using a primer selected from the group consisting of: SEQ. ID NO 5, SEQ. ID NO 6, SEQ. ID NO 7, SEQ. ID NO 8, SEQ. ID NO 9, SEQ. ID NO 10, SEQ. ID NO 11, SEQ. ID NO 12, SEQ. ID NO 13, SEQ. ID NO 14 or SEQ. ID NO 16; and observing or measuring the amplified nucleic acid sequence. The fungal species can thereby be detected, quantified, and / or identified. Fungal contamination also can be detected or measured in a biological or feed or food sample.

Isolated nucleic acids, kits and methods are disclosed for detecting, quantifying and / or identifying a fungal species in a sample or for diagnosing jejunal hemorrhage syndrome in a subject. The methods generally include amplifying a fungal nucleic acid sequence present in the sample using a primer selected from the group consisting of: SEQ. ID NO 5, SEQ. ID NO 6, SEQ. ID NO 7, SEQ. ID NO 8, SEQ. ID NO 9, SEQ. ID NO 10, SEQ. ID NO 11, SEQ. ID NO 12, SEQ. ID NO 13, SEQ. ID NO 14 or SEQ. ID NO 16; and observing or measuring the amplified nucleic acid sequence. The fungal species can thereby be detected, quantified, and / or identified. Fungal contamination also can be detected or measured in a biological or feed or food sample.

Method and apparatus for using computer controlled, fiber-coupled laser delivery of treatment specific wavelength, intensity and duration of UV irradiation to control bacterial, fungal, viral and mold infections in bodily cavities, fluids and external applications. The method of treatment is focused on DNA breakdown beyond repair by natural DNA repair mechanisms of the pathogen, with less than damaging doses to tissues being treated, thus avoiding mutagenicity and carcinogenicity. The minimal intensity and duration and exposure area of any given surface of tissue to be treated is to be pre-determined by tissue and pathogen testing to optimize the therapeutic ratio. External applications include specifically Trichophyton Rubrum (toenail fungus) through the nail and Pseudomonas Aeruginosa infections in burns and elsewhere.

The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include antibody, antibody fragment, siRNA and vaccine compositions having or directed against a GRP78 polypeptide or an antigenic fragment of the polypeptide.

The invention relates to a preparation method of a methanal-free, mildew-free and incombustible bamboo shaving board, and belongs to the field of bamboo based panels. The preparation method of the methanal-free, mildew-free and incombustible bamboo shaving board comprises the following steps that (1) primary screening of bamboo processing residues is carried out; (2) stratified screening of bambooshavings is carried out; (3) the bamboo shavings are classified and dried; (4) the bamboo shavings are classified for mildew proof treatment; (5) the mildew-proof bamboo shavings are classified and dried; (6) methanal-free and incombustible cementing materials are applied to the mildew-proof bamboo shavings in a classified manner; (7) pavement of the bamboo shavings with glue is carried out; (8)prepressing of a plate blank is carried out; (9) hot pressing of the plate blank is carried out; and (10) post-treatment is carried out. The bamboo shaving board does not contain methanal, and is notprone to mildew; and the bamboo shaving board has the characteristic of being not prone to being burned at the same time, the value of mold infection can reach zero, and the combustion performance level can reach the incombustible level A2.

The invention relates to a preparation method of a formaldehyde-free non-mildew non-combustible bamboo fiber board, and belongs to the field of bamboo-wood artificial boards. The preparation method ofthe formaldehyde-free non-mildew non-combustible bamboo fiber board comprises the following steps that (1), the bamboo sections are prepared; (2), a bamboo section longitudinal section, a tabasheer and an inner section are prepared; (3), bamboo blocks are subjected to shaving; (4), bamboo chips are used for preparing bamboo fibers; (5), the bamboo fibers are subjected to mildew-proof treatment; (6), the mildew-proof bamboo fiber is dried; (7), a formaldehyde-free non-combustible cementing material is applied to the mildew-proof bamboo fiber; (8), a glue applying bamboo fiber paving is carriedout; (9), a plate blank is pre-pressed; (10), hot pressing is performed on the plate blank; and (11), post-treatment is carried out. The prepared bamboo fiber board does not contain formaldehyde, isnot easy to mildew, and meanwhile has the characteristic of difficult combustion; and the mold infection value can reach zero, and the combustion performance grade reaches the non-combustible A2 grade.

The invention discloses an efficient and safe chitosan derivative-based disinfection liquid and a preparation method thereof, wherein the components of the formula comprise 0.05-10 g of a chitosan derivative, and 100 ml of sterilized deionized water. According to the present invention, the efficient and safe chitosan derivative-based disinfection liquid has characteristics of exact treatment effect, no toxic-side effect and no irritating to skin, can be used as the sterilization disinfection agent in the medical treatment, can be used for disinfecting skin and mucous membrane, can be used for treating scald, trichomonas vaginitis, fungal vaginitis, skin mold infections, fungal infections and the like, can further be used for burn injury, frostbite, knife wounds, abrasions, contusion and other general trauma, and can be used for pre-surgery disinfection, disinfection of other skins, disinfection of skins in various injection sites, equipment soaking disinfection, disinfection before vaginal surgery, and the like.

A model of systemic mold / Aspergillus infection in a profoundly immunocompromised host has been established in the beagle dog. The beagle was rendered immunosuppressed using a combination of total body irradiation and daily steroids, which provided a window of time where the mold could be successfully inoculated through a bronchoscope. This created a localized infection in one lung lobe, which subsequently spread diffusely throughout the lung parenchyma, and uniformly resulted in the animal's death. The invention contemplates the further study of the pathophysiology of opportunistic mold infections in vivo and also provides examples for the development of new antifungal agents and more effective combinations of agents. Finally, the invention contemplates the development of technology for the early detection of systemic mold infections. The inventors envision, that the use of the model should help save patients from clinical trials of antifungal drugs that may be effective in vitro without living up to the expectations in a clinical setting.

The invention relates to a pharmaceutical composition for controlling poultry mould infection, which comprises natamycin, Radix Astragali polysaccharide, cellulose, xylanase, protease, anhydrous glucose, etc. The invention has good control effects for immunity decrease, gastrointestinal tract inflammation, forage dyspepsia and other symptoms of poultry caused by forage and environment mould infection. The invention has the advantages of definite therapeutic effect and cheap price and the materials are easily available, and the composition is an ideal medicament for treating poultry mould infection.

The invention discloses an odontobutis obscura parent fish nursing propagation method. The nursing propagation method includes the steps that odontobutis obscura adult fish from different sources are selected as the parent fish from November to March in the next year, and fish nests for spawning are prepared; the fish nests with egg clusters and nursing male fish are moved to an incubation pond, and the male fish are used for nursing incubation; the male fish are moved from the egg clusters with eyespots, and the egg clusters are incubated in a concentrated mode; concentrated culture management is carried out on young fish. The nursing characteristics of the odontobutis obscura male fish are used, the odontobutis obscura male fish are made to nurse oosperm development until eyespots appear, the male fish are moved 3-5 days before incubation, the egg clusters are taken out to be concentrated artificial incubation, it is avoided that oosperms are infected with mold to die massively, the oosperms in the same development stage can be selected and incubated in a concentrated mode, it is effectively ensured that fry emergence is uniform, which is beneficial for culture management on fry, the oosperm incubation rate and the survival rate of fry culture are effectively increased, and the problems that at present, during artificial propagation of odontobutis obscura, odontobutis obscura oosperms are long in incubation time and prone to mold infection, and the incubation rate is not ideal are solved.

The invention relates to a preparation method of an aldehyde-free non-mildew non-combustible recombined bamboo floor, and belongs to the field of bamboo artificial floors. The preparation method of the aldehyde-free non-mildew non-combustible recombined bamboo floor comprises the following steps that (1), bamboo sections are prepared; (2), a bamboo section longitudinal section, a tabasheer and aninner section are prepared; (3), bamboo blocks are subjected to longitudinal wire rolling; (4), cord fabric type bamboo bundle is dried; (5), mildew-proof treatment is performed on the cord fabric type bamboo bundle; (6), the mildew-proof cord fabric type bamboo bundle is dried; (7), an aldehyde-free non-combustible cementing material is applied to the mildew-proof cord fabric type bamboo bundle;(8), the glue-applied cord fabric type bamboo bundle assembly blank is prepared; (9), an aldehyde-free non-mildew non-combustible recombined bamboo rough edge plate or square material is pressed; (10), the rough edge plate or square material is subjected to thermal refining; and (11), the post-processing of the non-formaldehyde non-mildew non-combustible recombined bamboo floor is achieved. The prepared recombined bamboo floor does not contain formaldehyde and is not easy to mildew, and meanwhile has the characteristic that the combustion is not easy; and the mold infection value can reach 0,and the combustion performance grade reaches the non-combustible A2 grade.

The invention relates to methods of treatment and prevention of aquatic mold infections in aquatic organisms and methods of disinfecting equipment used in raising aquatic organisms. The methods comprise use of one or more stilbene derivatives, including 4,4′-bis-(1,3,5-triazinylamino)stilbene-2,2′-disulfonic acid derivatives.

The invention discloses handmade essential oil soap for balancing grease and a preparation method of the handmade essential oil soap, and belongs to the technical field of biochemical engineering. Thehandmade essential oil soap for balancing grease is prepared from the following raw materials in parts by weight: cymbopogon citratus essential oil, crushed lemongrass leaves, mango seed grease, sheabutter, hyaluronic acid, radix angelicae powder, coconut oil, powder of Chinese herbal medicines including rhizoma atractylodis, radix angelicae, rhizoma bletillae, radix ampelopsis, radix paeoniae alba, poria cocos and batryticated silkworms, glycerin, rose essential oil, avocado oil, rosemary hydrosol, neroli hydrosol, honey, sodium hydroxide and deionized water. The handmade essential oil soapis prepared from natural plants, and can deeply clean pores, whiten skin and moisturize skin for a long time, uniquely added traditional Chinese medicine powder liquid can balance skin grease and hasgood curative effect on coarse pores, acne, oily skin and mold infection, different kinds of greasy skin are effectively balanced, skin is protected naturally and healthily, and the soap is a washingand protecting product capable of being used for a long time.

The present invention relates to one kind of bactericide composition. The bactericide composition is 20 % concentration benzoic acid-salicylic acid oil emulsion comprising benzoic acid 1-25 wt%, salicylic acid 1-25 wt%, methanol 10-25 wt%, xylene 15 -80 wt%, and 0206B emulsifier 6-10 wt%. The bactericide composition has the advantages of high efficiency, low toxicity, broad bactericidal spectrum, simple production process and other advantages. It possesses excellent effect of preventing and controlling bacterial, fungal and mold infections of vegetable, fruit tree, tea tree and other plants.

The invention provides a medicine composition for treating Trichomonas vaginalis and mycotic infection and a preparation method thereof, and belongs to the field of preparation technology of traditional Chinese medicine. The suppository is extracted and prepared by taking natural traditional Chinese medicines, namely peppers, kuh-seng, and root barks of shaggy-fruited dittany as raw material components. The medicine composition comprises the following various raw materials in proportion by weight: 40 portions of the peppers, 40 portions of the kuh-seng and 20 portions of the root barks of shaggy-fruited dittany. The suppository is prepared by using ethanol to soak medicines, reclaiming the ethanol, drying and crushing the medicines, and adding a fatty acid substrate. As proved by clinical tests and animal experimental research, the reagent has the function of obviously preventing and treating Trichomonas vaginalis and mycotic vaginitis, and has no obvious untoward reaction.

The invention relates to a traditional Chinese medicine composition, an oral liquid and a preparation method thereof for treating mold infection and mycotoxin poisoning of livestock and poultry. The traditional Chinese medicine composition comprises the following components by weight: 10-15 parts of American ginseng; 5 parts of Sophora flavescens ‑10 parts; capillary 10‑15 parts; artichoke 8‑10 parts; licorice 10‑30 parts; brown algae 5‑10 parts; potassium sorbate 2‑5 parts. In addition, the invention also discloses an oral liquid containing the Chinese medicine composition and a preparation method thereof. The traditional Chinese medicine composition of the present invention does not use antibiotics, and the oral liquid prepared by the present invention can effectively kill the mold existing in livestock and poultry, and at the same time reduce or slow down the body damage of livestock and poultry caused by mycotoxins.

Disclosed is the use of Serum Amyloid P component (SAP) polypeptides for the treatment of Eurotiomycetes fungi infections, in particular for aspergillosis and invasive aspergillosis, alone or in combination with pentraxin-3 (PTX3) polypeptides.

The invention discloses the new uses of 2 (2-hydroxypropyl) phenols. It is proved by the inventor of the invention through experiments that the 2(2-hydroxypropyl) phenol has a good antibacterial activity with a broad bactericidal spectrum, has distinguished inhibition ratio against various of pathogenic bacteria such as rhizoctonia solani on wheat, mildew germs on fruits, gray mold infection of tomato, and apples rot bacteria, and can be widely used for preparation of bactericidal agent.

The invention provides a method applied to diagnosis of the seedling stage of gray mold. The method comprises the following steps: detecting the content of ROS and calcium in leaves in the seedling stage according to disease index survey and analysis and determining standard indexes of gray mold infection as follows: ROS dyeing ratio is 0.53, and the content of calcium ions in the leaves is 139.45 micrograms per gram; in the actual diagnosis detection, when the ROS dyeing ratio is greater than or equal to 0.53 and / or the content of the calcium is greater than or equal to 140 micrograms per gram, the gray mold is avoided; when the ROS dyeing ratio is less than 0.53 and / or the content of the calcium is less than 140 micrograms per gram, the content of the calcium ions in the leaves can be regulated by taking a measure of applying fertilizer. The method has the characteristics of being simple to operate, good in repeatability and accurate in result; by virtue of the method, the method applied to diagnosis of the seedling stage of the disease is implemented; scientific basis and methods are provided for taking effective prevention measures in advance.

Enfumafungin derivative triterpenoid antifungal compounds are used to treat or prevent fungal infections occurring in or under acidic conditions where the pH is lower than about 7, due to their unexpected, enhanced efficacy under such conditions. The enfumafungin derivative triterpenoids (or pharmaceutically acceptable salts or hydrates thereof) are inhibitors of (1,3)-beta- D-glucan synthesis andare useful in the treatment or prevention of yeast or mold infections that occur in anatomic areas having a low pH, such as the vaginal cavity, or under acidic local environment conditions such of those seen in fungal abscesses, empyema, or upper gastrointestinal tract infections.

The invention relates to a traditional Chinese medicine composition for preparing anti-Aspergillus medicaments, which comprises the following components in parts by weight: cinnamaldehyde: 40-80 parts by weight, and patchouli ketone: 20-40 parts by weight. The pharmaceutical composition of the present invention can be used to treat diseases caused by aspergillus infection, such as pulmonary aspergillus infection, aspergillus sepsis including systemic infection of the whole body, including heart, brain, liver, kidney, pancreas and the like. The present invention has screened out patchouli ketone among many components of patchouli oil, and its antibacterial activity is higher, and has good synergistic effect with cinnamic aldehyde, and both are suitable for use after compatibility, and compare cinnamic aldehyde and cinnamaldehyde The antibacterial activity of Huoxiang oil after compatibility has been significantly improved, and the safety is good.

The invention relates to a storage box for soil element dry products, which includes a box cover, a box body, a partition, and a base. Convex edges arranged in pairs; the partitions and the convex edges are arranged at corresponding intervals inside the box body and sealed with the box body; the box body is in the shape of a cuboid, and the joints of each surface of the box body are fixed with anti-mildew tape; The base is arranged at the lower part of the box body, including a bottom plate and several support columns connecting the bottom plate and the box body; insect attractants and glue are arranged on the bottom plate; Made of bored cardboard. The present invention is used for the preservation of dry earthen products. By setting the base, moths and the like can be prevented from crawling into the box from the lower part of the box, and by setting partitions in the box, large-area infection caused by mildew of one soil element can be prevented, thereby It can effectively prevent mildew and moth, and prolong the shelf life of soil elements.

The invention provides a method applied to diagnosis of the seedling stage of gray mold. The method comprises the following steps: detecting the content of ROS and calcium in leaves in the seedling stage according to disease index survey and analysis and determining standard indexes of gray mold infection as follows: ROS dyeing ratio is 0.53, and the content of calcium ions in the leaves is 139.45 micrograms per gram; in the actual diagnosis detection, when the ROS dyeing ratio is greater than or equal to 0.53 and / or the content of the calcium is greater than or equal to 140 micrograms per gram, the gray mold is avoided; when the ROS dyeing ratio is less than 0.53 and / or the content of the calcium is less than 140 micrograms per gram, the content of the calcium ions in the leaves can be regulated by taking a measure of applying fertilizer. The method has the characteristics of being simple to operate, good in repeatability and accurate in result; by virtue of the method, the method applied to diagnosis of the seedling stage of the disease is implemented; scientific basis and methods are provided for taking effective prevention measures in advance.