Marine Streptomyces strain and use thereof

A marine Streptomyces and Staphylococcus technology, applied in bacteria, antifungal agents, antibacterial drugs, etc., can solve problems such as increased drug resistance and reduced efficacy of antibiotics
CN102220271AInactive Publication Date: 2011-10-19INST OF MICROBIOLOGY - CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
INST OF MICROBIOLOGY - CHINESE ACAD OF SCI
Publication Date
2011-10-19
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a marine Streptomyces strain and use thereof. The strain provided by the invention is Streptomyces sp. FXJ7.388, and the collection number of the strain is CGMCC No.4474. The invention also provides the use of the strain in the preparation of an antibacterial product. The antibacterial effect is to inhibit gram-positive bacteria, including Multi-resistant Staphylococcus aureus (MRSA 1-1), staphylococcus aureus CGMCC1.2386, bacillus subtilisGCMCC1.2428 and / or Candida albicans 2.538. Experiments prove that the Streptomyces sp. FXJ7.388 separated by the invention has the advantage of resisting gram-positive bacteria and Candida albicans, namely having high activity for resisting MRSA, staphylococcus aureus AND bacillus subtilis and certain inhibiting effect on Candida albicans.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to a strain of marine streptomyces and its application. Background technique

[0002] Actinomycetes are a class of Gram-positive bacteria with high G+C mol% content of genomic DNA and complex morphological differentiation. They are named because their colonies are mostly radial. Actinomycetes can produce a variety of biologically active substances with high economic value, including antibiotics, and are considered to be an important class of medicinal microbial resources. Among the more than 20,000 microbial-derived biologically active substances discovered so far, about Half are produced by actinomycetes.

[0003] The abuse of clinical antibiotics has sharply enhanced the drug resistance of pathogenic bacteria, and the efficacy of existing antibiotics has been greatly reduced. It is urgent to find new antibiotics. As the odds of discovering new active products in soil-derived actinom...

Claims

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