1861 results about "Staphylococcus bacteria" patented technology

The present invention relates to characterizing changes in mammalian bacterial gastrointestinal, cutaneous and nasal microbiota associated with antibiotic treatment and various disease conditions (such as asthma, allergy, obesity, metabolic syndrome, gastrointestinal reflux disease (GERD), eosinophilic esophagitis, gastro-esophageal junction adenocarcinomas (GEJAC), infections due to bacteria that are resistant to antibiotics, including Methicillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile, vancomycin-resistant enterococci, etc.) and related diagnostic and therapeutic methods. Therapeutic methods of the invention involve the use of live bacterial inoculants that are capable of restoring healthy mammalian bacterial gastrointestinal, skin, and nasal microbiota.

The invention provides an Enterococcus faecium ANSE228 of which the collection number is CGMCC No.4082. The invention also provides application of the Enterococcus faecium ANSE228 to inhibition of salmonella pullorum and/or Escherichia coli and/or Staphylococcus aureus. The Enterococcus faecium ANSE228 is obtained by processes of repeated separation, purification, rejuvenation and the like, and has high biological activity, obvious probiotic property, high adversity resistance and the like. The invention also provides a microecological agent which contains the Enterococcus faecium ANSE228. When the microecological agent is added into drinking water and/or feeds for breeding animals, the Enterococcus faecium ANSE228 can be quickly activated and reproduced and a dominant beneficial flora can be formed after the Enterococcus faecium ANSE228 is fed into intestinal canals of the animals, and the Enterococcus faecium ANSE228 has the effects of reducing a harmful flora in the intestinal canals, adjusting microecological balance of the intestinal canals, substituting for medicaments such as antibiotic and the like, and improving weight increment of the animals and the utilization rate of the feeds.

The invention relates to a biological denitrification method for salt-containing sewage, which comprises the following steps: adding a denitrification microbial inoculant into a biochemical sewage treatment system, and simultaneously starting the nitrification-denitrification biological denitrification treatment processes, wherein the sewage treatment temperature is 18-40 DEG C, the dissolved oxygen is 0.1-5 mg/L, and the pH value is 7.0-9.0. The denitrification microbial inoculant contains one or two of Staphylococcuscohnii FSDN-C, Arthrobactercreatinolyticus FDN-1 and Flavobacteriummizutaii FDN-2, and also contains one or two of Paracoccusdenitrificans DN-3 and Methylobacteriumphyllosphaerae SDN-3. The method provided by the invention can effectively treat high-salt-content sewage, enhances the adsorptivity and flocculence for sludge, has wide application range for wastewater quality and high impact resistance to salt-containing sewage, and obviously enhances the sewage treatment effect on the premise of removing pollutants, such as ammonia nitrogen, COD (chemical oxygen demand) and the like.

The invention discloses a traditional Chinese medicine inclusion compound with an antibacterial effect and a textile finishing method of the traditional Chinese medicine inclusion compound. The traditional Chinese medicine inclusion compound is prepared from traditional Chinese medicine extract liquid with the total ingredient percentage being 100 percent and beta-cyclodextrin through a saturated water solution method, wherein the traditional Chinese medicine extract liquid comprises the following ingredients in percentage by mass: 25 percent to 60 percent of honeysuckle, 15 percent to 50 percent of folium Artemisiae argyi, 20 percent to 35 percent of liquorice and 5 percent to 15 percent of scutellaria baicalensis. The traditional Chinese medicine inclusion compound and cross linking agents are added into chitosan acetic acid solution to be prepared into antibacterial finishing liquid. A simple rolling baking process is adopted for carrying out antibacterial finishing on the cellulose fiber, the process is simple, the finished textile has the broad-spectrum antibacterial performance on common germs such as staphylococcus aureus, escherichia coli and the like, and in addition, the water washing resistance performance is good.

Aqueous dilutions of acidic ternary compositions having unusually synergistic antimicrobial activity against Staphylococcus aureus and Salmonella choleraesuis microorganisms are disclosed. The compositions encompass ternary component mixtures of an alpha-hydroxycarboxylic acid, a monohydric water soluble alkanol and an anionic tenside having a Ternary Ratio residing within a defined phase region wherein synergistic antimicrobial activity is observed; whereas mixtures outside of the defined phase region and those lacking any one of the components do not exhibit synergistic activity. Compositions, methods and articles employing the inventive ternary synergistic compositions, and their utility in sanitizing and disinfecting hard surfaces are described.

Described herein are novel SCCmec right extremity junction (MREJ) sequences for the detection and/or identification of methicillin-resistant Staphylococcus aureus (MRSA). Disclosed are methods and compositions based on DNA sequences for the specific detection of MREJ sequences designated types xi, xii, xiii, xiv, xv, xvi, xvii, xviii, xix, and xx for diagnostic purposes and/or epidemiological typing.

The invention discloses a method for preparing a nanofibre membrane, belonging to a technique for preparing a nanofibre compound membrane. The method comprises the following steps: preparing curcuminethanol solution and chitosan acetum, mixing the curcumin ethanol solution and the chitosan acetum by the volume ratio thereof to prepare spinning solution which is injected into an injector of an electrostatic spinning device for electrostatic spinning to form a compound nanofibre membrane and to obtain a curcumin/chitosan nanofibre membrane of antibacterial property, wherein the diameter of thecurcumin/chitosan nanofibre membrane is 200-400 nm. The invention has the advantages that the preparation process is simple, the prepared membrane material heals wound, has broad spectrum bactericidalproperty and has higher bacterial inhibition rate to colibacillus and staphylococcus aureus for 24h.

The invention relates to nano-silver antibacterial melt-blown non-woven fabric and a production method thereof. The nano-silver antibacterial melt-blown non-woven fabric is characterized in that the fabric contains hybrid nanoscale antibacterial powder, a non-woven fabric base stock can be polypropylene, polyester or polyphenylene sulfide, the hybrid nanoscale antibacterial powder is formed in a way that nanoscale zirconium phosphate and silver nitrate are exchanged in water to form silver phosphate, zinc oxide needs to be added in the exchange process, and the antibacterial powder has the proportion of ingredients as follows: 2-5 percent of the silver nitrate, 90-95 percent of the zirconium phosphate and 1-5 percent of the zinc oxide. The nano-silver antibacterial melt-blown non-woven fabric has excellent inhibition and stop effects on escherichia coli, staphylococcus aureus, Candida albicans and the like, and can filter various particles with the pm (particulate matter) over 2.5 in current air haze, the filter efficiency is over 95 percent, and the antibacterial ratio is over 99 percent; the fabric is tested by sgs (Societe Generale de Surveillance); the prepared nano-silver antibacterial melt-blown non-woven fabric is good in strength, not easy to break, soft and comfortable.

The invention provides an N, P and S-codoped fluorescent carbon quantum dot and a preparation method and application thereof, and belongs to the technical field of luminescent nanomaterials. The preparation method comprises the steps that a biological bacterium (saccharomycete or escherichia coli or staphylococcus aureus or aspergillus niger) is taken as a carbon source, water of the corresponding volume is added, and a hydrothermal reaction is performed to obtain a dark brown solution; after the reaction stops and a reaction kettle is naturally cooled, dialysis is performed to remove impurities, an aqueous carbon quantum dot solution is obtained, and after freeze drying is performed, the N, P and S-codoped fluorescent carbon quantum dot is obtained. According to the method, the biomass is taken as the carbon source, the raw material is wide in source, low in cost, green and environmentally friendly, the technology is simple, and the preparation condition requirement is low. The obtained carbon quantum dot can be applied to detection on Cr (VI) ions, MnO4<-> and ascorbic acid by serving as a switch-type fluorescent probe and also can be used for cell imaging.

One finishing solution of fabrics containing chitosan is composed of Chitosan (MW <= 5000, the degree of deacetylation of >= 90%, 1.00 - 5.00%), acetic acid (0.50 - 6.00%), epichlorohydrin (0.01 - 1.00%) and water. The process for the fabric finishing is: I,fabric Pretreatment: fabric by the alkali treatment (8 - 11% NaOH at room temperature), washed, acid and (2 - 4% acetic acid at room temperature), drying (85 - 100 deg.C). II,finishing: baptist, rolling (room temperature, 15 to 25 min, rolling rate of more than 80 - 90%), alkali (room temperature, 5 - 8% NaOH), acid and (room temperature, 1 to 3% acetic acid) and Drying (85 - 100 deg.C). The test results show that the inhibitory rate for staphylococcus aureus, Escherichia coli, Streptococcus white Nian is more than 99% which is the higher level compared to the state 3-A class standard. The fastness of fabrics reaches 4 after washing.

Embodiments concern methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. Aspects include methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody that binds Staphylococcal protein A (SpA).

Disclosed are compounds represented by general formula (I) or pharmacologically acceptable salts or solvates thereof having excellent antimicrobial activity against bacteria causative of severe infections such as pneumonia and septicemia, particularly against MRSA, and also antimicrobial agents comprising these compounds, and pharmaceutical compositions comprising these compounds as an active component.

The invention provides a polyhexamethylene guanidine propionate disinfectant and a preparation method thereof. The polyhexamethylene guanidine propionate disinfectant is a hydrophilic solution prepared by the following steps: adding polyhexamethylene guanidine propionate, citric acid and surfactant to water and uniformly stirring the mixture at normal temperature. The polyhexamethylene guanidine propionate disinfectant has the advantages of broad spectrum of disinfection, quick results, long-time disinfection capability, high safety, non-toxicity, environmental protection, high stability, easy application, quick infiltration and volatilization, no coloration, easy cleaning, and the like. The polyhexamethylene guanidine propionate disinfectant has strong sterilization functions for colon bacillus, staphylococcus aureus, candida albicans, and the like with two-year effective periods. The polyhexamethylene guanidine propionate disinfectant can be used for disinfection of skins, wound surfaces, hands, air, departments of gynecology and urology, drinking water, and the like, thereby being a novel and ideal disinfectant.

The invention provides a plant bacteriostatic composition and application thereof in cosmetics. The plant bacteriostatic composition is obtained by compounding a licorice extract, a honeysuckle extract and a Mangnolia officinalis extract. The plant bacteriostatic composition has good bacteriostatic effect and particularly has a synergistic effect of inhibiting escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, candida albicans and aspergillus niger. The plant bacteriostatic composition can be applied to skin-care and washing cosmetics, reduces the adding amount of original preservatives and enables a product to have both antibacterial and anti-inflammatory effects.

The invention provides an oral antibacterial composition containing nisin and polylysine. According to the composition, the growth of oral pathogenic bacteria such as porphyromonas gingivalis, actinobacillus actinomycetemcomitans, streptococcus mutans, lactic acid bacillus, staphylococcus aureus and candida albicans can be effectively inhibited, and tooth decay, gingivitis, periodontitis, ozostomia and the like can be prevented; the composition can be prepared into toothpaste, mouth wash, refreshing and tasting chips and chewing gum which are used for preventing and treating oral diseases. Meanwhile, the invention provides a preparation method of the compositions such as the toothpaste, the mouth wash, the refreshing and tasting chips and the chewing gum. The oral antibacterial composition prepared through the method can prevent and treat various oral diseases and has no toxic and side effect and allergy or stimulation phenomenon on a human body.

The invention discloses a water-based UV anti-bacterial coating. The water-based UV anti-bacterial coating comprises, by weight, 60-80 parts of urethane acrylate dispersoid, 5-15 parts of nano-silver collosol, 5-20 parts of reactive diluent, 3-6 parts of photoinitiator, 0.1-1 part of flatting agent, 0.1-1 part of dispersing agent and 0.1-1 part of antifoaming agent. The invention further provides a preparing method of the water-based UV anti-bacterial coating. In the water-based UV anti-bacterial coating and the preparing method thereof, the sterilization rate of the water-based UV anti-bacterial coating on escherichia coli and staphylococcus aureus can be 95% or above, and the anti-bacterial effect is good. By means of the water-based UV anti-bacterial coating, automatic assembly line coating can be achieved, construction is convenient, the curing speed is high, and broad application prospects are achieved.

The invention belongs to the field of antibacterial polymer materials and a processing method thereof, and particularly relates to a polyaniline composite antibacterial plastic as well as a preparation method and application thereof. The antibacterial plastic comprises a polyaniline main material and a polymer basis material, various forms of polyaniline or composite materials thereof, which are used as main antibacterial materials, and then are blended with other polymer basis materials, and then injection molding, blow molding, mould pressing, foaming and other plastic molding processes are carried out to obtain the polyaniline composite antibacterial environment purification material; and at a normal temperature, polyaniline can be dissolved or dispersed by solvents, and surface treatment is carried out on the plastic by being mixed with other polymers, for example, antibacterial antifouling and anticorrosive coatings and the like are manufactured through spray molding, casting, film painting, electrochemical deposition and other processes. The polyaniline composite material not only has an excellent antibacterial effect on escherichia coli, staphylococcus aureus, Candida albicans and the like, but also can be used as the environment purification material by utilizing the oxidoreduction characteristic to realize the removal of methanal, hydrothion, pollutant and other gases to keep the air fresh.

The invention relates to a preparation method and application of an electrochemical immunosensor for a biomarker, namely a recombinant proprotein convertase subtilisin kexin type 9 (pcsk9) protein for predicting and diagnosing cardiovascular diseases, and belongs to the technical field of electrochemical detection. The preparation method is characterized by comprising the following steps: firstly, performing nitrogen doping on a graphene nanobelt (n-gnrs), performing amination on a fullerene-palladium-platinum nanoparticle (n-C60/pdpt) composite material and a staphylococcus aureus a protein (spa), and performing layer-by-layer self-assembling so as to immobilize a pcsk9 antibody (ab1); mixing the synthesized nanoparticle-poly-methylene blue (pt-pmb) with the pcsk9 antibody (ab2), and preparing a nano beacon, thereby obtaining the electrochemical immunosensor for pcsk9 protein detection. The electrochemical immunosensor has the advantages of being high in sensitivity, good in specificity and rapid and convenient in detection. A novel method for pcsk9 protein detection is provided, and useful information is provided for clinical prediction and diagnosis on cardiovascular diseases.

The invention discloses a polymer film with antifouling and anti-bacterial functions and a preparation method of the polymer film. Silver-containing nano particles are uniformly dispersed in the polymer film, and the surfaces of the silver-containing nano particles are coated with silver ions through chemical bonds. The adsorption amount of the polymer film to bovine serum albumin in unit area is 10 micrograms per square centimeter below, and the secondary water flux recovery rate of the separation film reaches 95% above. The kill rate of the polymer film for escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, candida albicans and yeast is 100%.