Chitosan oligosaccharide composite powder with adjuvant hpyerglycemic function and preparation method thereof

A technology of chitosan oligosaccharide and compound powder is applied in the functions of food ingredients, food ingredients containing yeast, food ingredients containing natural extracts, etc. Adjusting islet function, low molecular weight, good water solubility

Inactive Publication Date: 2016-05-25
颐海产业控股有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for most diabetic patients and people susceptible to diabetes, long-term adherence to taking hypoglycemic drugs and supplementary products will produce certain side effects such as indications and adverse reactions, which will cause greater psychological pressure. Therefore, the hypoglycemic products currently on the market The r

Method used

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  • Chitosan oligosaccharide composite powder with adjuvant hpyerglycemic function and preparation method thereof
  • Chitosan oligosaccharide composite powder with adjuvant hpyerglycemic function and preparation method thereof
  • Chitosan oligosaccharide composite powder with adjuvant hpyerglycemic function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A kind of preparation method of chitosan oligosaccharide, concrete steps are as follows:

[0033] (1) Chitosan and water are joined in the high-speed shearing disperser with the ratio of 0.1Kg / L, and after running at 2000 rpm for 2 minutes, add glacial acetic acid according to the weight ratio of chitosan aqueous solution: glacial acetic acid=6:1; After running for 15 minutes, add 12000U / kg (chitosan) chitosan hydrolase, and control the temperature at 53°C;

[0034](2) When the viscosity drops below 800cp and the pH is 4.8, control the stirring speed to 4000rpm, continuously add chitosan powder, and add glacial acetic acid according to the volume ratio of 3 parts of glacial acetic acid per 100 parts of chitosan solution. Dissolve, add chitosan hydrolase according to the consumption of chitosan hydrolase in step 1) again simultaneously, until the concentration of chitosan solution reaches 12%, pH5.0, add chitosan hydrolase 12000U in solution afterwards / kg (chitosan), a...

Embodiment 2

[0040] An oat beta-glucan prepared by the following method, the specific steps are as follows:

[0041] (1) Select barley bran without enzymes and impurities, add 2 times of pure water to soak twice, dry with hot air at 65°C for 2 hours, and then crush through a 60-mesh sieve;

[0042] (2) Add 15 times the amount of pure water (w / v) to the barley bran powder obtained in step (1), adjust the pH value to 9.5, heat up to 100°C, and add 0.15% barley bran dry matter in 3 times ( w / w) high temperature-resistant α-amylase, added once every 3 hours for hot alkali extraction, and filtered to collect the filtrate;

[0043] (3) Concentrate the enzymolysis filtrate obtained in step (2) to an aqueous solution (w / v) of 12 times the dry matter of the initial barley bran, adjust the pH value to 9.5, maintain the temperature at 60° C., and let stand for 4 hours. Precipitate protein, filter to remove protein and collect filtrate, add high temperature resistant α-amylase with 0.1% (w / w) dry mat...

Embodiment 3

[0049] A kind of chitosan oligosaccharide composite powder with the function of assisting in lowering blood sugar, which is prepared by weight from the following components: 40Kg of oat β-glucan, 10Kg of chitosan oligosaccharide, 20Kg of Polygonatum extract, 8Kg of mulberry leaf extract, and balsam pear extract 2Kg of food, 0.1Kg of chromium-enriched yeast, 5Kg of whey protein concentrate, 4.9Kg of L-arabinose, and 10Kg of isomalt. The oligochitosan and oat β-glucan are respectively the oligochitosan and oat β-glucan prepared in Example 1-2, and the Polygonatum extract, mulberry leaf extract and bitter gourd extract are purchased from Weihai Songling Nokejia Chinese Medicine Pieces Co., Ltd.

[0050] The preparation method is as follows:

[0051] (1) Dissolve oat β-glucan, chitosan oligosaccharides, sealwort extract, mulberry leaf extract, and bitter melon extract in 2 times the amount of pure water according to the weight ratio of the components, stir evenly, and heat to a t...

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Abstract

The invention relates to a chitosan oligosaccharide composite powder with adjuvant hpyerglycemic function. The chitosan oligosaccharide composite powder comprises, by weight, 40 to 60 parts of oat beta-glucan, 5 to 20 parts of chitosan oligosaccharide, 5 to 20 parts of sealwort extract, 3 to 8 parts of mulberry leaf extract, 2 to 6 parts of balsam pear extract, 0.05 to 0.5 part of chromium-rich yeast and 10 to 20 parts of a filler. The invention has the following advantages: the chitosan oligosaccharide composite powder is a chitosan oligosaccharide compound prepared from chitosan oligosaccharide and oat beta-glucan, used as main effective components, and a plurality of traditional Chinese medicinal active components, used as adjuvant materials, through refining in virtue of ultrasonic emulsification and spray drying technologies; the chitosan oligosaccharide composite powder has the advantages of good dissolvability, good dispersibility and high absorption and availability; all the components of the chitosan oligosaccharide composite powder cooperate with each other to exert substantial effect on promotion of blood glucose metabolism and maintenance and adjustment of the functions of the pancreas islet; moreover, a variety of active components included in the chitosan oligosaccharide composite powder has obvious synergism in improving the sensitivity of insulin and stabilizing postprandial blood sugar.

Description

technical field [0001] The invention relates to the field of health care products and a preparation method thereof, in particular to a chitosan oligosaccharide composite powder with an auxiliary function of lowering blood sugar and a preparation method thereof. Background technique [0002] Diabetes mellitus is an endocrine metabolic disease characterized by hyperglycemia, glucosuria, and impaired glucose tolerance. Modern medicine believes that diabetes is an endocrine disorder caused by absolute or relative insufficiency of insulin in the body, which causes sugar, fat, and protein metabolism disorders and secondary water and electrolyte metabolism disorders. It is an incurable lifelong disease. [0003] With the continuous improvement of people's living standards in our country, the material life is becoming more and more abundant, and the prevalence of diabetes is showing a trend of rapid growth. Its various complications such as cardiovascular, kidney, fundus and nerve l...

Claims

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Application Information

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IPC IPC(8): A23L29/30
CPCA23V2002/00A23V2200/328A23V2250/21A23V2250/76
Inventor 王尚龙李丽杰李八方
Owner 颐海产业控股有限公司
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