14 results about "High myopia" patented technology

The invention discloses a multi-modal information fused high-myopia retina image classification method and system. The method comprises the following steps: acquiring an OCT image of a to-be-classified high-myopia retina and structured numerical data corresponding to the image; the OCT image is preprocessed, the preprocessed image is input into an image encoder for high-dimensional semantic representation learning, and overall semantic vector representation of the image is obtained; converting the structured numerical data into a medical language description text, and inputting the medical language description text into a text encoder for deep semantic modeling to obtain overall semantic vector representation of the text; inputting to a multi-modal fusion module, carrying out feature interaction and fusion through a bidirectional cross attention mechanism, and generating a fused multi-modal feature; and outputting a retina splitting stage category corresponding to the OCT image through a classification module. According to the method, the OCT image, the structured numerical data and the split staging definition text are utilized to perform multi-modal feature fusion, so that the accuracy of image staging recognition is improved.

This utility model discloses an adjustable pupillary distance clip-on eyeglasses lens suitable for clinical optometry, comprising a frame and a replaceable lens body. The frame has a clamping part; the frame includes a frame beam, which is hollow inside and contains a first magnet, the length of which is less than the length of the frame beam. The bottom of the frame beam is flat, and the first magnet has an adjustment slider for adjusting the position of the first magnet inside the frame beam; the replaceable lens body includes a frame beam, which contains a second magnet, which is cylindrical and can rotate around an axis inside the frame beam; a lens is fixedly mounted on the bottom surface of the frame beam, and the top of the frame beam is a flat surface that matches the bottom of the frame beam. This solution allows people with moderate to high myopia, hyperopia, and astigmatism who need different prescriptions for near and far vision to conveniently clip an additional near lens onto their existing lenses while wearing their original eyeglasses, and the pupillary distance can be adjusted to suit different people.

A ring focus spectacle lens (1) for controlling the progression of myopia, and a manufacturing method therefor. The ring focus spectacle lens (1) can provide clear vision for a patient, and also has a plurality of ring-shaped defocusing zones to provide an optical defocusing effect. Since there is no joint between successive concentric rings of different optical powers that are tangent to each other, the ring focus spectacle lens (1) is as aesthetic as a common spectacle lens. In the manufacturing method, three front mold cores (71), a rear mold core (72), and a planar rear mold core are used to manufacture a series of ring focus spectacle lenses (1) having different powers, thereby reducing the number of mold cores and the production cost. In addition, for the requirements of individuals with severe myopia and astigmatism, a semi-finished lens is provided by means of the manufacturing method, which not only greatly reduces the number of mold cores, but also reduces the inventory quantity of desired lenses, thereby reducing costs.

The application provides an rs10045697 related SNP marker combination for predicting the risk and susceptibility of high myopia based on equivalent spherical lenses and an application thereof, and relates to the field of biological medicine. Specifically, the application screens a key SNP marker rs10045697 and a plurality of SNP sites related to high myopia in a high myopia queue based on whole genome association study (GWAS), and a model constructed based on the SNP marker combination can realize risk stratification and susceptibility detection of high myopia, is suitable for ophthalmic screening, high-risk population identification and precise prevention and control intervention, and has important clinical transformation value.

The application discloses a refractive correction implant, which is used for implanting into an anterior chamber of a human eye and comprises a lens body, a connecting part and a fitting part, the fitting part is used for being adsorbed to an inner wall of a cornea of the human body, the lens body is used for correcting the refractive of the eye, the lens body is located at a middle position of the inner wall of the cornea, and a gap is formed between the lens body and the inner wall of the cornea, the connecting part is located between the lens body and the fitting part and is used for connecting the lens body and the fitting part, and a through hole is formed in the connecting part and is used for allowing aqueous humor in the anterior chamber to flow through. The refractive correction implant can be used for treating refractive ophthalmic diseases such as high myopia and the like, and does not cause damage to the cornea of the human body, and is safe and reliable.

The invention relates to the technical field of high polymer materials, and discloses an artificial lens as well as a preparation method and application thereof. The intraocular lens is prepared from the following raw materials: 2-phenylethyl acrylate, 2-styrene methacrylate, a cross-linking agent and an initiator. According to the artificial lens provided by the invention, the balance between the crosslinking density and the material toughness is relatively good, the microcavitation density after accelerated aging is remarkably reduced compared with that of an existing product, the flashing phenomenon is effectively inhibited, and long-term definition and visual quality can be better kept; the intraocular lens is high in thermal stability, the initial decomposition temperature can reach 295 DEG C, and high-temperature sterilization and subsequent processing are facilitated; in clinical application, the artificial lens can reduce visual interference such as glare and halo, reduces secondary operation risks, is suitable for long-term implantation of ametropia patients such as cataract and high myopia, and can provide safer and more lasting visual quality guarantee for the patients.

The present application relates to the field of image processing, especially to a high myopia cataract image processing system based on image recognition, comprising a target analysis module, used to determine the image analysis strategy of the target processing object according to the image reference index and the imaging interference proportion; a reference processing module, used to determine the setting mode of the reference analysis set of the target processing image based on the feature dynamic recurrence coefficient and the recurrence area overlap coefficient, and respond to the processing reference condition to determine the reference processing mode of the target processing image; a reference division module, used to execute the setting mode of the reference analysis set of the target processing image determined by the reference processing module; a stable analysis module, used to determine whether to perform signal attenuation compensation on the target processing image according to the signal attenuation index of the execution reference image according to the effect execution difference coefficient, the present application improves the image processing efficiency of the patient's eye image.

The invention discloses an rs62226057 related SNP marker combination for evaluating a high myopia risk based on an ocular axis and application of the rs62226057 related SNP marker combination, and relates to the field of biological medicines. According to the invention, through large-scale queue analysis, a group of SNP marker combination based on the length of the ocular axis is screened and verified, and the key site in the SNP marker combination is rs62226057. The invention further provides a method, a system and equipment for evaluating the high myopia risk based on the SNP marker combination, an important tool is provided for identification and accurate intervention of people with the high myopia risk, and the method, the system and the equipment have wide clinical application value.

The present disclosure provides a myopia prevention and control method, device, electronic equipment and storage medium, which is applied to a red light therapeutic instrument. The method comprises the following steps: determining a myopia level based on a numerical range of the user's diopter, including a first myopia level, a second myopia level and a third myopia level; obtaining the diopter value of the user's both eyes; determining the target myopia level of the user according to the diopter value, which is one of the first myopia level, the second myopia level and the third myopia level; matching the corresponding myopia prevention and control mode according to the target myopia level, which is applied to the red light therapeutic instrument to prevent and control myopia; wherein the myopia prevention and control mode is one of the first myopia prevention and control mode, the second myopia prevention and control mode and the third myopia prevention and control mode corresponding to the myopia level. Thus, through the personalized myopia prevention and control mode matching based on the user's diopter value, the risk of retinal light damage of the high myopia population can be effectively reduced, and the prevention and control effect and safety can be improved.

The invention provides an rs10045697 related SNP (Single Nucleotide Polymorphism) marker combination for predicting high myopia risk and susceptibility based on an equivalent spherical mirror and application of the rs10045697 related SNP marker combination, and relates to the field of biological medicines. Specifically, a key SNP marker rs10045697 and a plurality of SNP loci related to high myopia are screened based on equivalent spherical power in a high myopia queue through genome-wide association study (GWAS), and a model constructed based on the SNP marker combination can realize risk stratification and susceptibility detection of high myopia. The method is suitable for ophthalmology screening, high-risk group identification and accurate prevention and control intervention, and has important clinical transformation value.

This invention discloses a combination of rs62226057-related SNP biomarkers for assessing the risk of high myopia based on axial length and its applications, relating to the biomedical field. Through large-scale cohort analysis, this invention screened and validated a set of SNP biomarkers based on axial length, with rs62226057 as the key locus. This invention also provides a method, system, and device for assessing the risk of high myopia based on this SNP biomarker combination, providing an important tool for identifying and precisely intervening in individuals at high myopia risk, and has broad clinical application value.

The application discloses a kind of comprehensive prevention and control methods of juvenile myopia, comprising the following steps: implement centralized scientific prevention and control propaganda and education;For intervention object, establish and maintain a set of personalized dynamic vision health records;According to the baseline refractive state of intervention object, determine and execute one of the four types of hierarchical prevention and control targets, namely "preclinical prevention, low myopia management, moderate myopia control, high myopia complication prevention";Synchronous execution includes six-dimensional collaborative intervention measures, including health education push, eye behavior supervision, visual environment standardization, structured nutritional support, mandatory outdoor activities and professional clinical intervention package.The comprehensive scheme of the application shows significant advantages in eye axis growth control, myopia degree progress control and naked eye vision improvement and other key indicators compared with only routine refractive correction.The scheme can effectively slow down the growth of eye axis, control myopia deepening and improve naked eye vision, and its effect is significantly better than single intervention or routine correction.

The application provides an application of WNT7B in constructing a myopia animal model. Homologous genes wnt7ba and wnt7bb of WNT7B in zebrafish are knocked out or knocked down by using a CRISPR / Cas9 gene editing technology, and an animal model with a significantly increased eye axial length, a significantly reduced eyeball movement frequency and a reduced light response is obtained, which indicates that WNT7B is related to high myopia. The model provides an advantageous tool for a pathogenesis and drug screening of high myopia and has a good application prospect.

The invention discloses a biomarker for detecting high myopia complicated with optic neuropathy, a detection kit and application, and belongs to the technical field of biomedical detection. The technical problem to be solved is that a biomarker for detecting high myopia complicated with optic neuropathy is lacked in the prior art. The key point of the technical scheme is to provide application of CCN2 (Cell Communication Network Factor 2) in preparation of a reagent for detecting high myopia concurrent optic neuropathy.