36 results about "Glaucoma drainage device" patented technology

A glaucoma drainage device may comprise a main drainage tube with a first end configured to be located in an anterior chamber of an eye and a second end configured to be located in a drainage location. A bypass drainage tube is fluidly coupled to and in parallel with the main drainage tube. A pump is in communication with the bypass drainage tube. The pump comprises a first driver and a first flexible membrane enclosing a first chamber. A first check valve is located upstream of the pump, and a second check valve is located downstream of the pump. An active valve is located upstream of the first check valve. The active valve comprises a second driver and a second flexible membrane enclosing a second chamber. A third check valve is located between the active valve and the second end of the main drainage tube. A volume of the first chamber is changed to pump fluid from the anterior chamber to the drainage location.

A sensor system for sensing an intraocular pressure within an eye includes a glaucoma drainage device and a pressure sensor. The glaucoma drainage device has an explant plate and a lumened tube, the explant plate being adapted to fit over the eye, and the lumened tube being adapted to be inserted into the eye. The pressure sensor is operably attached to the glaucoma drainage device for sensing the intraocular pressure of the eye and for generating a sensor signal representative of the pressure.

Described herein is a device for glaucoma treatment and monitoring that comprises a combination of an intraocular pressure (IOP) sensor and a glaucoma drainage device. The device comprises an IOP sensor and an inductive antenna mounted within a porous biocompatible material that forms the drainage path. The IOP sensor is mounted in a footplate portion of the device and is mountable in the anterior chamber of an eye. The footplate portion is connected to a body portion that houses the spiral antenna by a neck portion which retains the footplate portion in a suitable position within the anterior chamber. Due to its size, the footplate portion housing the IOP sensor can readily be inserted into the anterior chamber with the body portion housing the spiral antenna located outside of the anterior chamber in a sub-scleral space to disperse the aqueous humour.

A glaucoma drainage device has a tube shunting the anterior chamber to a drainage location. A power generator has a rotor coupled to a micro-generator. The power generator is configured to generate energy from aqueous flowing through the tube. The force required to drive the rotor can be controlled to control the flow of aqueous through the tube. Alternatively, energy generated by the power generator is stored in a power source that powers an active valve, a pressure sensor, or telemetry.

A glaucoma drainage device has a housing with an open outlet end. A tube is in fluid communication with the housing. An actuator is located in the housing. An actuation arm is located at least partially in the housing and is coupled to the actuator. A tapered arm is rigidly coupled to the actuation arm. A needle head is located opposite the tapered arm. A tapered end of the tapered arm is located at least partially in the tube. When the tapered arm is moved, it can clear an obstruction from the tube. When the needle head is moved, it can disperse aqueous or clear fibers from the drainage location.

In one aspect, the present invention provides an implant device for use in an eye with elevated intraocular pressure or glaucoma. In another aspect, the present invention provides a method for lowering intraocular pressure and / or treating a condition associated with elevated intraocular pressure using the implant device of the present invention.

A glaucoma drainage device may comprise a main drainage tube with a first end configured to be located in an anterior chamber of an eye and a second end configured to be located in a drainage location. A bypass drainage tube is fluidly coupled to and in parallel with the main drainage tube. A pump is in communication with the bypass drainage tube. The pump comprises a first driver and a first flexible membrane enclosing a first chamber. A first check valve is located upstream of the pump, and a second check valve is located downstream of the pump. An active valve is located upstream of the first check valve. The active valve comprises a second driver and a second flexible membrane enclosing a second chamber. A third check valve is located between the active valve and the second end of the main drainage tube. A volume of the first chamber is changed to pump fluid from the anterior chamber to the drainage location.

A glaucoma drainage device has a housing with an open outlet end. A tube is in fluid communication with the housing. An actuator is located in the housing. An actuation arm is located at least partially in the housing and is coupled to the actuator. A tapered arm is rigidly coupled to the actuation arm. A needle head is located opposite the tapered arm. A tapered end of the tapered arm is located at least partially in the tube. When the tapered arm is moved, it can clear an obstruction from the tube. When the needle head is moved, it can disperse aqueous or clear fibers from the drainage location.

A glaucoma drainage device regulator (GDDR) is disclosed which comprises a membrane and a lumen to regulate the flow of aqueous in conjunction with different ocular (e.g., glaucoma) filtering procedures. In connection with aqueous shunting, the GDDR can be placed over the tip of a shunt tube in the anterior chamber, either at the time of initial surgery or also in devices which have been previously implanted. In connection with trabeculectomy, the GDDR can comprise a flange for seating the GDDR at the sclerostomy in trabeculectomy surgery.

The invention provides an intraocular drainage implant whose drainage capacity is regulated by opening a plurality of laser-sensitive spots. The implant is useful for fine regulation of the eye fluid outflow in handling glaucoma.

Various embodiments of the invention relate to a glaucoma valve, a casing for containing a glaucoma valve and a glaucoma drainage device comprising the glaucoma valve and / or the casing. The valve includes a flow channel having an inlet and an outlet and a valve member connected to the outlet of the flow channel. The valve member may be formed from a degradable polymer or a combination of degradable polymer and non-degradable polymer. Various embodiments of the invention relate to a glaucoma valve, the valve having a first flow channel. The interior of the first flow channel may be coated with a degradable polymer, such that in use, the polymer degrades to allow a greater flow of fluid through the flow channel. In some embodiments, the valve includes a second flow channel, which may be arranged in parallel to the first flow channel. The first flow channel may be completely sealed with the polymer such that in use, the polymer degrades to allow fluid to flow through the first flow channel. Various embodiments relate to a casing for containing a glaucoma valve. The casing may be formed from a degradable polymer, such as a biodegradable polymer.

The invention discloses a glaucoma valve and a glaucoma drainage device, and relates to the technical field of medical apparatus and instruments. The glaucoma valve comprises a pipe. Liquid can be drained by the pipe, and an adjusting component capable of adjusting the size of an outlet of the pipe is arranged in the pipe. The glaucoma drainage device comprises the glaucoma valve. The glaucoma valve and the glaucoma drainage device have the advantages that the size of the outlet of the pipe can be controlled by the adjusting component which is arranged in the pipe of the glaucoma valve, accordingly, the flow of the liquid in the pipe can be accurately controlled, the drainage volume of the glaucoma valve can be matched with repair procedures of the bodies of patients, and complications of glaucoma filtration surgery can be reduced.

The invention discloses a biocompatible drainage pipe for glaucoma aqueous humor and a preparation method thereof. A template-freezing method is used for preparing a chitosan micro tube which is usedas a glaucoma drainage device, so that a stable biocompatible aqueous humor drainage channel is obtained. The preparation technology is simple, and the cost is low. The obtained chitosan micro drainage tube facilitates sterilization, packaging and transportation, and is a glaucoma aqueous humor drainage product which is low in cost, portable and practicable.

A glaucoma drainage device regulator (GDDR) is disclosed which comprises a membrane and a shunt tube to regulate the flow of aqueous in conjunction with different ocular (e.g., glaucoma) filtering procedures. In connection with aqueous shunting, the membrane of the shunt tube of the GDDR can be placed in the anterior chamber of the eye during implantation and coupled to a reservoir. The GDDR is implanted in a manner to permit easy access to the membrane for post surgery perforation of the membrane to regulate the aqueous flow of the shunt tube.

A biocompatible glaucoma drainage device, comprising a non-porous element, a porous element, an anchoring assembly disposed around the non-porous element, wherein the anchoring assembly comprises a plurality of barbs extending outwardly therefrom.

A biocompatible glaucoma drainage device, comprising a non-porous element, a porous element, an anchoring assembly disposed around the non-porous element, wherein the anchoring assembly comprises a plurality of barbs extending outwardly therefrom.

An implantable glaucoma drainage device (GDD) system is disclosed. The GDD system comprises a microflow control system for controlling intraocular pressure, a protective capillary carrier tube housing the microflow control system, and anchoring arms holding the implanted device in place. The overall GDD size can be in a needle-implantable form factor for minimally invasive implantation. The GDD may be implanted via subconjunctival needle implantation to mimic the normal aqueous humor drainage pathway.

The invention relates to application of pure magnesium / coating composite in the preparation of glaucoma drainage devices; a glaucoma drainage device made with the pure magnesium / coating composite candegrade and be absorbed by tissues autonomously; it is fully shown that the pure magnesium / coating composite can inhibit the proliferation of Tenon's capsule fibroblasts and decrease scar; magnesium ions released during degradation can protect visual nerves. Compared with traditional titanium alloy, the pure magnesium / coating composite causes significantly low cytotoxicity to the fibroblasts, andcan effectively inhibit the proliferation of Tenon's fibroblasts, reduce specific protein alpha-SMA expression and inhibit activity of the fibroblasts.

The invention relates to a glaucoma drainage device, which consists of a drainage pipe (a pipe for short) and a drainage sheet (a membrane sheet for short), wherein the pipe and the membrane sheet can be simultaneously or singly used, the pipe has the length of 0-15mm, the inner diameter of 1-1500[mu]m, and the outer diameter of 3-3000[mu]m, the membrane sheet has the thickness of 0-3mm, and the area of 0-500mm<2>, the aqueous water can smoothly flow in the inner side surface of the membrane sheet, the inner side surface of the membrane sheet is provided with 0-N dot-shaped or line-shaped grooves, and the depth and the width of each groove are respectively 0-5mm; the drainage sheet is in a shape of semicircle, ellipse, sector and triangle. As the equipment adopts the material, such as silica rubber, the easiness in direct pricking into the anterior chamber of eyes is avoided, a metal chip is assisted by the applicable shape of the silica rubber, and the metal chip is provided with a handle to assist the soft material (such as silica rubber) in pricking into the anterior chamber of eyes. The glaucoma drainage device has the advantages that the material of equipment adopts medical silica rubber, hydrogel or other metallic human body implantable materials; the size of equipment is small, the appearance design conforms to the anatomy principle of human eyes, and the device is suitable for being arranged in any position of conjunctival sac for a long time.

The invention provides a glaucoma drainage implant. The glaucoma drainage implant comprises a hollow cylindrical pipe, wherein a friction increase structure for increasing the frictional resistance isarranged outside a pipe wall of the cylindrical pipe along the length direction. The invention further provides a glaucoma drainage device. According to the glaucoma drainage device and the glaucomadrainage implant thereof provided by the invention, the frictional force between the glaucoma drainage implant and a schlemm tube is increased through the arrangement of the friction increase structure on the outer wall of the cylindrical pipe, so that movement is avoided and the long-term treatment effect is good.

The invention provides an injector which is used for pushing a glaucoma drainage implant into a schlemm tube. The injector comprises a shell, a guide rail and an adjusting assembly, a holding part anda head part connected to the holding part are arranged on the shell, and a through groove is formed in one end of the head part; the guide rail is arranged in the through groove and used for containing the glaucoma drainage implant and guiding pushing of the glaucoma drainage implant, and part of the guide rail protrudes out of the shell; and the adjusting assembly is at least partially exposed out of the head and used for providing pushing power, so that the glaucoma drainage implant can be pushed to the schlemm tube along the guide rail. The invention further provides a glaucoma drainage device. The glaucoma drainage device and the injector thereof are good in pushing effect and high in accuracy.

The invention provides a glaucoma drainage device which is used for draining aqueous humor to tissues or lymphatic vessels. The device comprises: a drainage disc which is provided with an upper surface and a lower surface, wherein the upper surface is provided with a plurality of drainage grooves which are uniformly dispersed in a spoke shape, and a drainage tube groove is arranged between the upper surface and the lower surface; a drainage tube which penetrates through the drainage tube groove and is used for inflow of aqueous humor; and a liquid storage chamber which is vertically arranged at the central position of the drainage disc, is connected to the drainage tube which penetrates through the drainage tube groove, is further communicated with the multiple drainage grooves and is usedfor containing the aqueous humor guided to the liquid storage chamber through the drainage tube groove by means of the drainage tube, wherein the aqueous humor in the liquid storage chamber flows into the multiple drainage grooves after overflowing, and a covering layer is arranged above the liquid storage cavity and used for covering the liquid storage cavity and the communication positions of the drainage grooves and the liquid storage cavity. The problems that drainage devices are uneven in outflow and prone to being blocked are solved.

The invention provides a glaucoma drainage implant. The glaucoma drainage implant comprises a hollow cylindrical pipeline, a friction increasing structure for increasing friction resistance and a through groove are formed in the outer portion of the pipe wall of the cylindrical pipeline in the length direction, the through groove is formed in the length direction of the outer portion of the pipe wall of the cylindrical pipeline, the through groove enables the interior of the cylindrical pipeline to communicate with the outside from the side face so as to increase the aqueous humor circulationarea, and the width of the through groove is 20-130 micrometers. The invention further provides a glaucoma drainage device. According to the glaucoma drainage device and the glaucoma drainage implantthereof, the friction increasing structure is arranged on the outer wall of the cylindrical pipeline, so that the friction force between the glaucoma drainage implant and a schlemm pipe is increased,movement is avoided, the long-term treatment effect is good, and the aqueous humor circulation area is large.

The invention provides a glaucoma drainage device, and relates to the technical field of medical instruments. The glaucoma drainage device comprises a drainage body and a flow guide body, the drainage body comprises a hollow drainage main body and a main drainage tube, and the drainage main body is communicated with the main drainage tube; the flow guide body comprises a flow guide base and a flow guide pipe arranged on the flow guide base, and the flow guide pipe is communicated with the drainage body. By the adoption of the drainage device, aqueous humor is drained through the drainage body, the aqueous humor flows in through the main through hole and the auxiliary through hole, the effects of filtering and shunting the aqueous humor are achieved, and the main through hole and the auxiliary through hole are prevented from being blocked; the sclera bed and the sclera flap are separated through the flow guide pipe, continuous existence of a functional liquid cavity gap is maintained, a permanent aqueous humor drainage channel is built, and adhesion between sclera is effectively prevented. The problem that the operation effect is affected due to cicatrization of a filtering channel after the glaucoma operation at present is solved.