An intelligent
system for optimizing radiotherapy for personalized radiotherapy, consisting of: • a
genome data acquisition module configured to acquire and process a patient's genomic, molecular, and biomarker information; • a multimodal
medical imaging module configured to acquire medical image data from one or more
imaging modalities; • an
image processing and
automatic segmentation module configured to preprocess the acquired medical images, register multimodal images, segment tumors and organs at risk, and extract quantitative image features; • an
artificial intelligence and
data integration module configured to integrate
genome data,
imaging data, radiomic features, and
clinical information to generate a patient-specific predictive model;• A treatment planning and
dose optimization module configured to automatically generate and optimize a
personalized treatment plan based on the integrated patient-
specific model; • A digital twin and adaptive therapy module configured to simulate the patient-specific
treatment response and continuously adjust the
treatment plan during therapy; • A
treatment monitoring and
outcome prediction module configured to predict
treatment response,
disease progression, and
radiation-induced
toxicity based on longitudinal
patient data; • A
clinical decision support module configured to generate
personalized treatment recommendations and support
clinical decision-making;• A communication and
data management module configured for the secure exchange, synchronization, and storage of clinical, imaging, genomic, and treatment-related information; and • An autonomous learning and
systems management module configured to continuously improve predictive models and treatment optimization algorithms based on collected treatment outcomes, with the modules working together to generate, optimize, monitor, and continuously adapt personalized radiotherapy based on integrated genomic and multimodal
medical imaging information.