The utility model discloses a kind of guiding device when facial deep layer bone phase fills, including patch, the edge of the patch is provided with support, the support is rotatably connected with connecting seat, and guide rod, the central axis of the guide rod is provided with the first through-hole for injection needle to pass, the guide rod is close to facial one end and is provided with the connecting rod extending along radial, the connecting rod and the connecting seat are rotatably connected, so that the angle of the guide rod and face is adjustable.The guiding device when facial deep layer bone phase fills, with the beneficial effect of accurate guidance reduces the risk of misoperation.