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Preparation method of medical metal implant material porous tantalum

An implant material and porous tantalum technology, applied in the field of porous medical metal implant materials, can solve the problems of carbon skeleton residue, insufficient purity of finished products, and reduced biological safety, and achieve uniform quality, reduce impurity content, and improve porosity. Effect

Active Publication Date: 2014-04-23
CHONGQING RUNZE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the limitations of its preparation method, the purity of the obtained finished product is not enough, and there are carbon skeleton residues, resulting in a decrease in biological safety

Method used

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  • Preparation method of medical metal implant material porous tantalum
  • Preparation method of medical metal implant material porous tantalum
  • Preparation method of medical metal implant material porous tantalum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1: Weigh 8 g of ethyl cellulose and put it into a container containing 240 ml of absolute ethanol; place it on an electric stove to heat and stir to make it an ethyl cellulose ethanol solution. Use a 200g balance to weigh 60g of tantalum powder with an average particle size of less than 10 microns and an oxygen content of less than 0.1%, add 8ml of cooled ethyl cellulose ethanol solution, stir and mix evenly, and make it into a tantalum powder slurry. Use 10×10×30mm porous polyurethane foam (average pore diameter is 0.48mm, density 0.025g / cm 3 , hardness 50°) into it and pour until the pores of the polyurethane foam are filled with the tantalum powder slurry, then use a clamp to take out the polyurethane foam filled with the tantalum powder slurry and put it into a porcelain plate. Dry in a vacuum drying oven at a drying temperature of 70° C., a drying time of 5 hours, and a vacuum degree of 1 Pa. Degreasing treatment: vacuum degree 1×10 -3 Pa~1×10 -4 Pa, tem...

Embodiment 2

[0035] Example 2: Weigh 5 g of ethyl cellulose and put it into a container containing 200 ml of absolute ethanol; place it on an electric stove to heat and stir to make it an ethyl cellulose ethanol solution. Use a 200g balance to weigh 40g of tantalum powder with an average particle size of less than 10 μm and an oxygen content of less than 0.1%, add 6ml of ethyl cellulose ethanol solution, stir and mix evenly, and make it into a tantalum powder slurry. Use 10×10×25mm porous polyurethane foam (average pore diameter is 0.56mm, density 0.030g / cm 3 , hardness 60°) into it and pour until the pores of the polyurethane foam are filled with the tantalum powder slurry, then use a clamp to take out the polyurethane foam filled with the tantalum powder slurry and put it into a porcelain plate. Dry in a vacuum drying oven at a drying temperature of 80°C for a drying time of 4 hours and maintain a vacuum of 1×10 -2 Pa. Degreasing treatment: vacuum degree 1×10 -3 Pa, temperature 800°C,...

Embodiment 3

[0038] Example 3: Weigh 6 g of ethyl cellulose and put it into a container containing 220 ml of absolute ethanol; place it on an electric stove to heat and stir to make it an ethyl cellulose ethanol solution. Use a 200g balance to weigh 45g of tantalum powder with an average particle size of less than 10 μm and an oxygen content of less than 0.1%, add 8ml of ethyl cellulose ethanol solution, stir and mix evenly, and make it into a tantalum powder slurry. Use 8×8×25mm porous polyurethane foam (average pore diameter is 0.70mm, density 0.035g / cm 3 , hardness 70°) into it and pour until the pores of the polyurethane foam are filled with the tantalum powder slurry, then use a clamp to take out the polyurethane foam filled with the tantalum powder slurry and put it into a porcelain plate. Dry in a vacuum drying oven, the drying temperature is 90 ° C, the drying time is 4.5 hours, and the vacuum degree is kept at 1×10 -1 Pa. Degreasing treatment: the vacuum degree is lower than 1×1...

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Abstract

The invention relates to a preparation method of medical implant material porous tantalum. The preparation method comprises the following steps: preparing tantalum powder slurry from a solution prepared from ethyl cellulose and anhydrous ethanol and tantalum powder, pouring into an organic foam body, soaking till pores of the organic foam body are filled with the tantalum powder slurry, then drying to remove a dispersant in the organic foam body poured with the tantalum powder slurry, performing degreasing treatment under a protective atmosphere of inert gas to remove an organic binder and the organic foam body, sintering in a vacuum state to prepare a porous sintered body, further annealing in the vacuum state, and performing conventional post-treatment to prepare the porous tantalum, wherein the average particle size of the tantalum powder is less than 10mu m, and the oxygen content is less than 0.1%. The porous tantalum medical implant material prepared by the preparation method provided by the invention has great biocompatibility and relatively good mechanical properties, and is particularly suitable for being used as the medical implant material for coupling members at wounds or defects of shoulder bone, skull and facial bone tissues. Simultaneously, the preparation method has the advantages of simple process and easiness in control; and the whole preparation process has no harm, no pollution, no toxic and harmful dust and no side effects against a human body.

Description

[0001] The application of the present invention is a divisional application with application number 201010547076.8, application date November 17, 2010, and the title of the invention "a method for preparing porous tantalum as a medical metal implant material". technical field [0002] The invention relates to a porous medical metal implant material, in particular to a method for preparing porous tantalum as a medical implant material, in particular to a porous tantalum implant suitable for light-bearing parts of the human body and having good biocompatibility. The method of preparation of the input material. Background technique [0003] Porous medical metal implant materials have important and special purposes such as treating bone tissue trauma and femoral tissue necrosis. The common materials of this type include porous metal stainless steel and porous metal titanium. As a porous implant material used in the treatment of bone tissue trauma and femoral tissue necrosis, its...

Claims

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Application Information

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IPC IPC(8): C22C1/08C22C27/02A61L27/04A61L27/56
Inventor 叶雷
Owner CHONGQING RUNZE PHARM CO LTD
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