77 results about "Porous implant" patented technology

The implant includes an outer layer of ePTFE which exhibits extensibility normally not associated with ePTFE. The ePTFE is reduced in length by deforming the fibrils between the nodes while maintaining the nodes in a substantially flat configuration. Various implant configurations that can include the outer layer described are also disclosed.

A porous implant system includes a gradient source adapted for transferring a gradient to an interface connected to an implant at a patient situs. The gradient source is controlled by a programmable controller. The implant is bonded to the patient by tissue ingrowth, which is facilitated by the gradient formed across the porous portion of the implant. A treatment method and includes the steps of providing a porous implant, connecting same to a gradient source through an interface, forming a gradient across the implant and controlling the operation of the gradient source according to a predetermined and preprogrammed treatment protocol.

A system and method for the repair of damaged tissue and bones, congenitally missing tissue/cosmetic reconstruction of tissue is described. The system has a layered porous structure with a sufficiently large area of exposed pores to promote neo-vascularization as well as bone and tissue formation. The disclosed porous implant system can contain bioactive agents necessary for rapid tissue formation and keep ingrowth of unwanted tissue out of the implant surgical site. The implant can be reinforced with an additional, stronger polymer layer and/or may include an endoskeleton or exoskeleton for dimensional stability.

The exemplary embodiment of the present invention are provided which relate to porous implants and methods for manufacture thereof which use powder molding techniques. For example, a suspension can be provided comprising a plurality of first particles of at least one organic polymer, a plurality of second particles of at least one metal-based material, and at least one solvent. The first and second particles can be substantially insoluble in the solvent. The suspension can be molded to form a green body comprising the first particles embedded in a matrix of compressed second particles. The first particles may be removed from the green body by thermally induced decomposition and/or evaporation. The green body can be sintered to form the implant. The removals of the first particles can be performed during sintering.

A bone implant comprises an active agent on at least a portion thereof. The active agent is locally deliverable to bone proximate the implant in at least a two-phased release scheme. A first phase rapidly releases a first quantity of the active agent, and at least a second phase gradually releases a second quantity of the active agent, whereby bone formation stimulated by the active agent is modulated. In one embodiment, a porous implant comprises a porous portion coated with a calcium phosphate compound and which is contacted with a bisphosphonate compound to form a bisphosphonate layer chemically bound to the calcium phosphate at the surface of the porous portion and to form bisphosphonate molecules being non-chemically attached inside the pores of the porous portion. The non-chemically attached bisphosphonate molecules are released in the subject at a rate greater than that of the chemically bound bisphosphonate layer.

An apparatus including a medical implant is provided. The medical implant includes a porous outer portion, and the apparatus further includes a dried, lubricious when wet, in vivo absorbable coating covering the porous outer portion. A method for finishing a medical implant is also provided. The method includes forming a porous outer portion on the implant, covering the porous outer portion with a lubricious when wet, in vivo absorbable coating, and drying the coating.

A dental implant can comprise a shaft defining a longitudinal axis and having an apical end, a coronal end, and an exterior surface. A portion of the exterior surface can include a porous material. The dental implant can comprise at least one thread, including a non-porous material, having an interior surface and a bone-engaging surface. The interior surface can engage and wind around the exterior surface of the shaft and the bone-engaging surface can extend outwardly from the exterior surface of the shaft. The shaft can include one or more channels configured to communicate a flowable material, stored within the shaft, to the exterior surface. Each channel can include an opening at the exterior surface to release the flowable material. At least one channel can extend between a cavity of the shaft and the exterior surface and can optionally be angled toward the apical end.

An implant which includes a shaft made of a first material and having an exterior surface, and at least one thread made of a second material different from the first material, engaging the exterior surface, and extending outwardly from the exterior surface for engaging bone. After implantation of the implant, bone tissue may osseointegrate into the porous shaft to anchor the implant within the surrounding bone. The first material may be a porous metal and include tantalum while the second material is non-porous.

Exemplary embodiments of the present invention relate to a stent, and in particular to at least partially biodegradable stent having at least one section made of a material having a particular porous structure.

The invention discloses a method for preparing a porous implant through gelcasting 3D printing and electroreduction. The preparation method comprises steps as follows: according to the human body features of a to-be-implanted part, a personalized gradient porous implant negative-type mold adopting a microstructure is designed by the aid of a medical image data reverse solution model; a gradient porous implant negative-type resin mold is prepared through photo-curing forming equipment; metal oxide ceramic slurry is injected into the negative-type resin mold through a gel injection mold and sintered at the high temperature, and a metal oxide ceramic porous scaffold is obtained; a primary porous metal implant is produced through molten salt in-situ reduction; a metal coating is deposited on the surface of the primary porous metal implant with a chemical vapor deposition method. The defects that implants with complex shapes, precise sizes and uncontrollable microstructures cannot be produced with a traditional porous implant preparation method are overcome, structure nanosizing can be realized, and a new way for preparing the porous implant is expected to be developed.

Exemplary embodiments of the present invention relate to an implant, e.g., a stent, and in particular to a stent having at least one section made of a material having a particular porous structure.

The common premise of synthetic implants in the restoration of diseased tissues and organs is to use inert and solid materials. Here, a porous titanium implant enables the delivery of microencapsulated bioactive cues. Control-released TGFβ1 promoted the proliferation and migration of human mesenchymal stem cells into porous implants in vitro. Upon 4-wk implantation in the rabbit humerus, control-released TGFβ1 from porous implants significantly increased BIC by 96% and bone ingrowth by 50% over placebos. Control-released 100 ng TGFβ1 induced equivalent BIC and bone ingrowth to adsorbed 1 μg TGFβ1, suggesting that controlled release is effective at 10-fold less drug dose than adsorption. Histomorphometry, SEM and μT showed that control-released TGFβ1 enhanced bone ingrowth in the implant's pores and surface. These findings suggest that solid prostheses can be transformed into porous implants to serve as drug delivery carriers, from which control-released bioactive cues augment host tissue integration.

The invention provides a method for preparing an individualized porous implant through selective laser formation and electrolytic reduction. The method comprises the following steps: according to human body characteristics of a part needing an implant, carrying out individualized porous implant design with a microstructure through utilizing a medical image data reverse model; preparing a metal oxide ceramic porous implant with a microstructure through utilizing a selective laser melting/sintering additive manufacturing method; carrying out the electrolytic reduction on molten chloride melt to obtain a primary porous metal implant with a nanostructure, and sintering at a high temperature; depositing the same metal coating on the surface of the primary porous metal implant by utilizing a chemical vapor deposition method. By adopting the method provided by the invention, the disadvantages of a traditional porous implant preparation method that the microstructure cannot be controlled and the difficulty of direct laser additive manufacturing is great are overcome; structure nano-crystallization can be realized, a new way for preparing the porous implant is hopefully explored; the method has an important meanning on promotion of clinical application of the porous implant.

Aiming to solve the problems that the mechanical property of the implant is reduced and that the mineralization bone is not easily formed in the implant existing in the technology for preparing the biomedical porous implant, the invention provides a biomedical porous implant and a method for preparing the same. The method comprises the following steps of: interweaving threads of the implant material to form a netty structure; pressing the netty structure into an implant coarse blank with a special shape; sintering the implant coarse blank so as to allow the material threads at cross points in the netty structure to form melting connection to prepare the implant. The plantation body prepared by the method can be used for preparing biomedical porous nickel-titanium alloy implants such as denda, artificial joints and the like and realizing the deep freezing treatment of hemangioma, ecphymata and keloid by carrying liquid nitrogen.