Method for preparing individualized porous implant through selective laser formation and electrolytic reduction

A selective laser and implant technology, applied in coatings, medical science, prostheses, etc., can solve the problems of inability to form nanostructures, difficult manufacturing, and uncontrollable microstructures, so as to improve biocompatibility and benefit The effect of cellular activity

Active Publication Date: 2017-02-15
XI AN JIAOTONG UNIV
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Problems solved by technology

[0004] In order to overcome the shortcomings of the difficulty of direct laser additive manufacturing of porous implants, the uncontrollable microstructure and the inability to form nanostructures, the purpose of the present invention is to provide a metal oxide ceramic with a micro-nano structure prepared by selective laser forming and electrolytic reduction. A personalized porous implant method, which combines the additi

Method used

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Embodiment

[0032] A method for preparing personalized porous implants by selective laser forming and electrolytic reduction, the method includes four steps of personalized macro-micro integrated design, selective laser melting / sintering additive manufacturing, molten salt electrolytic reduction and chemical vapor phase enhancement:

[0033] Take Ta 2 o 5 Preparation of personalized porous tantalum implants with micro-nano structure by selective laser forming and electrolytic reduction as an example. Firstly, a personalized porous tantalum implant model with microstructure is designed using three-dimensional software according to the physiological size, internal environment characteristics and lesion condition of the diseased tissue of the clinical patient. Then put Ta 2 o 5 Spherical powders were prepared using selective laser melting / sintering additive manufacturing equipment to prepare the designed implant models to obtain Ta 2 o 5 Porous implants. Ta 2 o 5 The porous implant i...

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Abstract

The invention provides a method for preparing an individualized porous implant through selective laser formation and electrolytic reduction. The method comprises the following steps: according to human body characteristics of a part needing an implant, carrying out individualized porous implant design with a microstructure through utilizing a medical image data reverse model; preparing a metal oxide ceramic porous implant with a microstructure through utilizing a selective laser melting/sintering additive manufacturing method; carrying out the electrolytic reduction on molten chloride melt to obtain a primary porous metal implant with a nanostructure, and sintering at a high temperature; depositing the same metal coating on the surface of the primary porous metal implant by utilizing a chemical vapor deposition method. By adopting the method provided by the invention, the disadvantages of a traditional porous implant preparation method that the microstructure cannot be controlled and the difficulty of direct laser additive manufacturing is great are overcome; structure nano-crystallization can be realized, a new way for preparing the porous implant is hopefully explored; the method has an important meanning on promotion of clinical application of the porous implant.

Description

technical field [0001] The invention relates to a method for preparing a personalized porous implant by selective laser forming and electrolytic reduction. The method belongs to the field of biological additive manufacturing (3D printing) and can be applied to the field of biomedicine. Background technique [0002] Additive manufacturing has important applications in the medical field, especially for the manufacture of personalized implants, which has unparalleled advantages and a potential market of tens of billions in the future. At present, implants manufactured by direct metal forming of various metal materials such as stainless steel, titanium alloy and cobalt-based alloy have been widely used in heart valve stents, vascular stents, digestive tract stents, bone repair and replacement stents and other stents clinically, and achieved better therapeutic effect. However, the complex environment in the human body will cause material corrosion and release of toxic elements, ...

Claims

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Application Information

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IPC IPC(8): A61L27/30A61L27/10A61L27/56C04B41/88C25C5/04
CPCA61L27/10A61L27/306A61L27/56C25C5/04C04B41/009C04B41/51C04B41/88A61L2420/06C04B35/01
Inventor 刘亚雄赵广宾陈旭黄亚江伍言龙安超李涤尘贺健康王玲连芩
Owner XI AN JIAOTONG UNIV
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