A preparation method of a porous implant based on polymer additive manufacturing

Abstract

The invention provides a preparation method for a porous implant based on additive manufacturing of a macromolecular polymer. The preparation method comprises the following steps that a macromolecular polymer negative-type mould of a porous implant model with a gradient microstructure is prepared through an additive manufacturing method; metal powder and adhesion agents are mixed evenly and pressed in the macromolecular polymer negative-type mould, then the metal powder and the macromolecular polymer negative-type mould are placed in an organic solvent for removing the macromolecular polymer negative-type mould, and a preliminary porous implant is obtained; the preliminary porous implant is placed in a vacuum high-temperature furnace, a metal coating is deposited on the surface of the implant through a chemical vapor deposition method, so that the strength of the implant is further enhanced; and finally, the metal porous implant is placed into an electrolyte to be subjected to anodic oxidation treatment, and the customized metal porous implant with a surface nanostructure is obtained. According to the preparation method, additive manufacturing and the powder metallurgy technology are combined, the problem that the pore size and pore distribution cannot be controlled is solved, nanocrystallization of the surface structure is achieved, and a new approach is opened for preparation of the porous implant with the macroscopic structure and the micro-nano structure.

Description

technical field [0001] The invention relates to a method for preparing a porous implant based on additive manufacturing, which belongs to the field of biological additive manufacturing (3D printing) and can be applied to the field of biomedicine. Background technique [0002] The traditional powder metallurgy-pore-forming agent method is the most effective method for preparing metal biomedical scaffolds. Different pore levels can be prepared. The porous structure of the scaffold is determined by the type, size and shape of the pore-forming agent. The internal microscopic pore structure distribution Inhomogeneous and difficult to control and customize preparation. Additive manufacturing technology has unparalleled advantages for the manufacture of personalized implants, and can prepare customized microstructures. [0003] The current porous implants do not have controllable macro-micro-integrated structures and nanostructures: rational design of macro- and micro-integrated s...

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the uncontrollable microscopic gradient structure of porous implant scaffolds and the inability to form nanostructures, the object of the present invention is to provide a method for preparing porous implants based on additive manufacturing, which combines additive manufacturing technology, powder The combination of metallurgical technology, chemical vapor phase technology and anodic oxidation technology can realize the controllable formation of microscopic gradient structures, and form nanostructures to facilitate cell activities and improve the biocompatibility of porous implants. It is expected to open up a new way for the preparation of porous scaffolds. Significant for promoting the clinical application of porous implants