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15 results about "Intraocular fluid" patented technology

Clear, watery fluid which fills the anterior and posterior chambers of the eye; it has a refractive index lower than the crystalline lens, which it surrounds, and is involved in the metabolism of the cornea and the crystalline lens.

Ophthalmic minimally invasive drainage device

The application provides an ophthalmic minimally invasive drainage device, and relates to the technical field of medical devices.The device comprises a drainage tube, a dispersion tube and a release tube fixed as a whole, the longitudinal section shape of the drainage tube, the dispersion tube and the release tube is flat, the left end of the drainage tube is provided with a liquid inlet assembly for liquid inlet; the upper part of the drainage tube is provided with a fixing assembly for limiting surgical thread; the dispersion tube is fixedly connected with a fixing lug; the release tube is in the shape of a circular arc, the right end of the release tube is provided with a pressure stabilizing membrane, and a pressure stabilizing port is arranged between the pressure stabilizing membrane and the release tube.The fixing assembly can limit surgical thread, ensure the stability of the drainage tube, improve the operation quality and reduce operation complications; the pressure stabilizing membrane and the pressure stabilizing port can change the size of the pressure stabilizing port by using the pressure deformation characteristics of the pressure stabilizing membrane, thereby ensuring the stability of the intraocular fluid pressure in the anterior chamber and being beneficial to the treatment of glaucoma.
Owner:XIAMEN EYE CENTER OF XIAMEN UNIVERSITY CO LTD

Intraocular fluid marker rapid detection method based on artificial intelligence

The invention relates to the technical field of biological material detection, in particular to an intraocular fluid marker rapid detection method based on artificial intelligence. The method comprises the following steps: firstly, collecting an intraocular fluid sample to be detected; obtaining a physical interference factor according to the color characteristic, the turbid characteristic and the flow characteristic of the intraocular fluid sample; acquiring a nucleic acid quality factor according to the concentration, purity and dominant characteristics of nucleic acid in the intraocular fluid sample; acquiring a matrix inhibition factor according to dripping morphological characteristics and pipetting liquid level characteristics of the intraocular fluid sample; and inputting the physical interference factor, the nucleic acid quality factor and the matrix inhibition factor of the intraocular fluid sample into a pre-trained circulation parameter recommendation model, and carrying out rapid detection on the marker of the intraocular fluid sample according to recommended circulation parameters output by the model. According to the method, the sample characteristic factors which reflect the influence of the intraocular fluid sample on the detection are quantified from different angles, and then the loop parameters are recommended through the neural network model for rapid detection, so that the detection efficiency and effect of the intraocular fluid marker are improved.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Ophthalmic surgical instruments

An ophthalmic surgical instrument includes a handpiece configured to be held by a user, and a working tip coupled to a distal end of the handpiece that includes a proximal opening configured to be disposed outside an eye, a distal opening configured to be disposed inside the eye and expose a tool to the inside of the eye, and a channel between the openings. When the distal opening is disposed inside the eye and the proximal opening is uncovered the proximal opening permits the channel to be in fluid communication with ambient atmosphere, the channel is configured to enable passive aspiration of fluid from inside the eye, such that the fluid flows from the distal to the proximal opening and into the ambient atmosphere. The tool comprises forceps, scissors, a delamination spatula, a pick, an illumination fiber, or a laser fiber.
Owner:ALCON INC

Fluid drainage devices, systems, and methods

ActiveUS12527691B2Eye surgeryWound drainsGlaucomaPeriocular tissue
A glaucoma shunt for draining a fluid from an eye to a tissue surrounding the eye, the glaucoma shunt being implantable within tissue of the eye, the glaucoma shunt includes a shunt body that is formed from a microporous material that is arranged so as to form a reservoir within the shunt body; and a conduit in fluid communication with the reservoir, the conduit being insertable into the eye such that the fluid at a distal end of the conduit is allowed to flow through the conduit and accumulate within the reservoir, wherein the microporous material transitions from a hydrophobic state to a hydrophilic state as the fluid that is accumulated in the reservoir diffuses to the tissue surrounding the eye through the microporous material so as to provide a variable flow resistance as the microporous material transitions from the hydrophobic state to the hydrophilic state.
Owner:WL GORE & ASSOC INC

Stent implant for treating glaucoma by means of intraocular fluid drainage from the anterior chamber

ActiveUS12661264B2StentsEye surgeryConjunctivaAnterior chamber eye
A stent implant for treating glaucoma by intraocular fluid drainage from the anterior chamber, for example into the suprachoroidal space. The stent implant is designed to change in shape after being inserted into the eye, during which change the width and / or thickness or the flow cross-section is increased by for example 20%, in another example more than 200%, and in a further example by more than 400%, at least one point of the stent implant. In the case of intraocular fluid drainage from the anterior chamber into the suprachoroidal space, a cyclodialysis cleft which may open can be largely or completely closed. With appropriate adjustments, the stent implant can also be applied in trabecular, uveoscleral, uveolymphatic and subconjunctival applications for intraocular fluid drainage from the anterior chamber. The implant can even be used for direct intraocular fluid discharge from the anterior chamber onto the surface of the eye.
Owner:CARL ZEISS MEDITEC AG

Ocular implant and method of manufacturing the same

ActiveCN115715214BEye implantsEye surgeryBiomedical engineeringOcular implant
An ocular implant (10) for delivering intraocular fluid from a site of intraocular fluid excess in a patient, the implant (10) comprising: a body (12) including one or more drainage channels (20), each having an outlet (24), the outlets being in fluid communication with a drainage site located away from the site of intraocular fluid excess; and an elongated tubular component (30) in fluid communication with the body (12), the component (30) having a first end portion (32) providing an inlet (38), a second end portion (34) providing an end (40), and so on. and a lumen extending between the inlet (38) and the end (40), wherein the inlet (38) is in fluid communication with the portion of the intraocular fluid excess, such that the intraocular fluid can flow through the inlet (38) and through the lumen to the end (40), and wherein the second end portion (34) includes one or more openings (42), each opening being in fluid communication with a corresponding drainage channel in one or more drainage channels (20) to allow the intraocular fluid to flow from the second end portion (34) to each outlet in the outlet (24).
Owner:WESTERN SYDNEY LOCAL HEALTH DISTRICT

Spacer device for insertion inside an eye to create a three-dimensional volume for controlling intraocular fluids.

Spacer device 800 for implantation into an eye, comprising a flexible body configured to conform to an anatomical tissue surface of the eye, the body comprising an inner surface 825 and an outer surface 845, wherein the spacer device is configured to reversibly transition between a compressed configuration suitable for feeding through an application element 400 and an expanded configuration defining a convex, internal three-dimensional volume 370 for receiving fluid from an anterior chamber of the eye, wherein the spacer device comprises engagement elements 810, 830, each positioned along and extending along a longitudinal axis of the inner surface 825, and wherein the engagement elements are configured to: (i) engage with an application element 400 to stabilize the spacer device during implantation into the eye, and (ii) engage with the tissue surface after insertion, and wherein a central slot 865 arranged between the engagement elements 810, 830 forms a primary drainage path for the fluid circulation.
Owner:HEXIRIS INC DIEPPE

Ocular implant and method of making same

An ocular implant (10) for conveying intraocular fluid away from a site of excess intraocular fluid within a patient, the implant (10) including: a body (12) including one or more drainage channels (20) each having an outlet (24) fluidly communicable with drainage site located away from the site of excess intraocular fluid; and an elongated tubular member (30) fluidly communicable with the body (12), the member (30) having a first end portion (32) providing an inlet (38), a second end portion (34) providing an end (40), and a lumen extending between the inlet (38) and the end (40), wherein the inlet (38) is fluidly communicable with the site of excess intraocular fluid so that the intraocular fluid is able to flow past the inlet (38) and through the lumen towards the end (40), and wherein the second end portion (34) includes one or more openings (42) each fluidly communicable with a respective one of the one or more drainage channels (20) to permit the intraocular fluid to flow from the second end portion (34) to each of the outlets (24).
Owner:WESTERN SYDNEY LOCAL HEALTH DISTRICT

Fluid drainage devices, systems, and methods

Glaucoma shunts for draining fluid from an eye to surrounding tissue and being implantable within eye tissue, the shunts include a shunt body formed from microporous materials arranged to form a reservoir within the shunt body, and a conduit having a proximal end in fluid communication with the reservoir and an opposing distal end, the distal end being insertable into the eye to facilitate drainage of fluid into the conduit via the distal end, wherein the conduit and the reservoir together define a flow passage along which drainage of fluid flows through the conduit, to the reservoir, and into surrounding tissue via the microporous material, wherein the flow passage presents a variable flow resistance along the conduit that has a plurality of sequential flow resistances with first and second flow resistances defined therein such that the first flow resistance is different from the second flow resistance.
Owner:WL GORE & ASSOC INC

Surgical system priming with pressure calibration utilizing handpiece orientation

ActiveUS12636187B2Eye surgeryDiagnosticsPressure dataPhacoemulsification
A phacoemulsification system and a method are described. The system including: a handpiece having a needle and a sleeve at a distal end and an orientation detection unit; an irrigation module configured to supply irrigation fluid into the eye; an aspiration module configured for aspiring eye fluid; a priming cover for fitting over the distal end of the handpiece during a priming process; external pressure sensors coupled with the priming cover; one or more sensors for monitoring at irrigation and spiration pressure; and a processor configured to operate in a priming process. The priming process includes operating the irrigation module to fill the irrigation channel with fluid and remove air bubbles. The one or more processors are configured for obtaining calibration pressure data from the external pressure sensors and orientation data from the orientation detection unit and for calibrating the sensors of the system in accordance with orientation data.
Owner:JOHNSON & JOHNSON SURGICAL VISION INC

Spacer device for deployment within an eye to create a three-dimensional volume for the management of intraocular fluids

PCT designated stageWO2026097171A1Eye surgeryProsthesisIntra ocular pressureOphthalmological implant
The disclosure relates to ophthalmic implants, specifically a flexible, self-expanding spacer device deployable in subconjunctival, sub-Tenon's, or suprachoroidal spaces to manage intraocular fluids. The device addresses limitations of fixed-resistance drainage and fibrosis-related failure in glaucoma surgery by maintaining a controlled three-dimensional reservoir (bleb space) for aqueous humor outflow while minimizing tissue trauma. In one aspect, a shape-memory body transitions from a compressed, delivery-compatible state to an expanded configuration defining a convex internal volume, optionally with collapse-resistant reinforcements and tissue-engaging elements for atraumatic stabilization. Preferred embodiments include anterior relief geometry to avoid corneal contact and posterior flow-directing features to promote posterior bleb formation and uniform pressure control. A delivery member with a reduced-profile, tapered piercing tip and optional bent shaft enables minimally invasive ab externo implantation and controlled, coaxial deployment. Advantages include streamlined single-step delivery, stable long-term bleb architecture, reduced hypotony and fibrotic encapsulation, and compatibility with trabeculectomy and shunt-based outflow.
Owner:HEXIRIS INC

Medical device for deployment within an eye for management of intraocular fluids

PendingUS20260124072A1Eye surgeryProsthesisIntra ocular pressureOphthalmological implant
The disclosure relates to ophthalmic implants, specifically a flexible, self-expanding spacer device deployable in subconjunctival, sub-Tenon's, or suprachoroidal spaces to manage intraocular fluids. The device addresses limitations of fixed-resistance drainage and fibrosis-related failure in glaucoma surgery by maintaining a controlled three-dimensional reservoir (bleb space) for aqueous humor outflow while minimizing tissue trauma. In one aspect, a shape-memory body transitions from a compressed, delivery-compatible state to an expanded configuration defining a convex internal volume, optionally with collapse-resistant reinforcements and tissue-engaging elements for atraumatic stabilization. Preferred embodiments include anterior relief geometry to avoid corneal contact and posterior flow-directing features to promote posterior bleb formation and uniform pressure control. A delivery member with a reduced-profile, tapered piercing tip and optional bent shaft enables minimally invasive ab externo implantation and controlled, coaxial deployment. Advantages include streamlined single-step delivery, stable long-term bleb architecture, reduced hypotony and fibrotic encapsulation, and compatibility with trabeculectomy and shunt-based outflow.
Owner:HEXIRIS INC

Apparatus and methods for treating excess intraocular fluid

ActiveUS12589030B2Eye surgeryWound drainsElevated intraocular pressureControl cell
An ocular drainage system is provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the system includes an implantable device and an external control unit, the implantable device includes a non-invasively adjustable valve featuring at least one deformable tube and a disk rotatably mounted within a housing, such that rotation of the disk using the external control unit causes the disk to apply a selected amount of compression to the deformable tube, thereby adjusting the fluidic resistance of the deformable tube and regulating the intraocular pressure.
Owner:ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

Spacer device for deployment within an eye to create a three-dimensional volume for the management of intraocular fluids

The disclosure relates to ophthalmic implants, specifically a flexible, self-expanding spacer device deployable in subconjunctival, sub-Tenon's, or suprachoroidal spaces to manage intraocular fluids. The device addresses limitations of fixed-resistance drainage and fibrosis-related failure in glaucoma surgery by maintaining a controlled three-dimensional reservoir (bleb space) for aqueous humor outflow while minimizing tissue trauma. In one aspect, a shape-memory body transitions from a compressed, delivery-compatible state to an expanded configuration defining a convex internal volume, optionally with collapse-resistant reinforcements and tissue-engaging elements for atraumatic stabilization. Preferred embodiments include anterior relief geometry to avoid corneal contact and posterior flow-directing features to promote posterior bleb formation and uniform pressure control. A delivery member with a reduced-profile, tapered piercing tip and optional bent shaft enables minimally invasive ab externo implantation and controlled, coaxial deployment. Advantages include streamlined single-step delivery, stable long-term bleb architecture, reduced hypotony and fibrotic encapsulation, and compatibility with trabeculectomy and shunt-based outflow.
Owner:HEXIRIS INC