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Ocular drainage system devices and methods

An eye and medical device technology, applied in the field of eye drainage system devices and methods, can solve the problems of reducing the absorption performance of surrounding tissues and the like

Pending Publication Date: 2021-06-29
WL GORE & ASSOC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This micro-motion sometimes results in micro-irritation of the surrounding tissue, which is known to lead to foreign body tissue reactions and excessive scarring, and thus reduces the absorptive properties of the surrounding tissue

Method used

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  • Ocular drainage system devices and methods
  • Ocular drainage system devices and methods
  • Ocular drainage system devices and methods

Examples

Experimental program
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Effect test

example 1

[0091] First, an ePTFE membrane approximately 0.150 inches in width was spirally wrapped around a silver-plated copper center wire approximately 0.010 inches in diameter, covering approximately 5 layers of ePTFE. The wrapped construction was then heat treated in a convection air oven at 360°C for about 10 minutes. Once cooled, the centerline is pulled and removed, leaving the patented ePTFE tubing.

[0092] Next, a small amount of two-part silicone (Nusil Inc., grade 4840, Carpinteria, CA 93013) was prepared, resulting in a thicker viscous liquid. The liquid was diluted 50% with n-heptane and mixed well.

[0093] Third, inject silicone fluid into the ePTFE tubing using a syringe with a 25-gauge needle attached. A 0.010 inch straight rod is then inserted into the fluid filled tube. The assembly was then subjected to a heat treatment at 115°C for about 15 minutes. Once cooled, the wire is removed, leaving a patented waterproof ePTFE tube with an exterior constructed to allow...

example 2

[0095] First, an ePTFE membrane approximately 0.070 inches in width was spirally wrapped around a silver-plated copper center wire approximately 0.005 inches in diameter, covering approximately 2 layers of ePTFE. The wrapped construction was then heat treated in a convection air oven at 360°C for about 10 minutes.

[0096] Next, a small amount of two-part silicone (Nusil Inc., grade 4840, Carpinteria, CA 93013) was prepared, resulting in a thicker viscous liquid. The fluid was diluted about 50% with n-heptane (Project No. 246654, Sigma-Aldrich Corp., St. Louis, MO) and mixed well.

[0097] Third, the wrapped mandrel is then held under tension horizontally and coated with an excess of viscous silicone barrel mix. The coated wrapped mandrel was then passed through pinched thumb and forefinger to meter excess silicone but still provide a coated outer surface.

[0098] Fourth, an ePTFE membrane approximately 0.070 inches wide was spiral wrapped around the coated wrapped mandrel....

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PUM

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Abstract

Ocular drainage systems are disclosed. In various embodiments, the ocular drainage systems include a compliant fluid conduit that is configured to be implanted within a biological tissue, such as tissues of an eye. The compliant fluid conduit includes an exterior having a microstructure that is configured to permit cellular ingrowth. A first end of the compliant fluid conduit is configured to be inserted into an eye of a patient to allow ocular fluid to drain from the eye, and a second end of the compliant fluid conduit is configured to be inserted into an ocular venous system of the patient to allow the ocular fluid drained from the eye to flow directly into the ocular venous system.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of Provisional Patent Application No. 62 / 724,180, filed August 29, 2018, the entirety of which is hereby incorporated by reference for all purposes. Background technique [0003] Aqueous humor is a fluid that fills the anterior chamber of the eye and contributes to intraocular pressure, or fluid pressure within the eye. Glaucoma is a progressive eye disease characterized by increased intraocular pressure. This increase in intraocular pressure is usually caused by insufficient amounts of aqueous humor being reabsorbed by the body. In some cases, the aqueous humor is not absorbed fast enough or not at all, while in other cases, the aqueous humor is additionally or alternatively produced too quickly. An increase in intraocular pressure is associated with gradual and sometimes permanent loss of vision in the diseased eye. [0004] Many attempts have been made to treat glaucoma, includin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/007A61F9/00
CPCA61F9/0017A61F9/00781A61L27/16
Inventor P·J·罗伯J·C·托勒
Owner WL GORE & ASSOC INC
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