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36 results about "Aversive agent" patented technology
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Aversive agents are unpleasantly flavored substances added to poisonous household goods in order to discourage children and animals from consuming the poisonous household products. Aversive agents are not intended to be harmful, only unpleasant. For example, to prevent children from consuming poisonous anti-freeze, which has a sweet flavor due to the ethylene glycol, an aversive agent is added, which gives the anti-freeze an unpleasant taste. There are two primary classes of aversive agents: bitterants, chemicals producing a bitter flavor, and pungent agents, chemicals producing an unpleasantly pungent flavor.
Abuse-resistant transdermal system
InactiveUS20070065365A1Complicates and preventsImprove solubilityOrganic active ingredientsIn-vivo testing preparationsAversive agentBULK ACTIVE INGREDIENT
An abuse-resistant transdermal system which contains, in addition to one or more active ingredients with potential for abuse, at least one gel-forming agent in quantities such that it forms a gel with a minimum quantity of an aqueous liquid, and contains as further agents which complicate or prevent abuse at least one emetic, and / or at least one dye as an aversive agent.
Owner:GRUNENTHAL GMBH
Oral dosage form safeguarded against abuse containing (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
The invention relates to an oral dosage form, which is safeguarded against abuse and which has a controlled release of (1R, 2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol for a once daily administering. The invention is characterized in that the oral dosage form comprises the active ingredient and / or one or more pharmaceutically acceptable compounds (A) thereof, at least one synthetic and / or natural polymer (C), retarding adjuvants, optionally comprises additional physiologically compatible adjuvants (B), and optionally comprises a wax (D). The oral dosage form has a breaking resistance of at least 500 N, preferably at least 750 N. The dosage form contains at least one of the following abuse-preventing constituents (a)-(f); (a) at least one substance that irritates the nasal and / or pharyngeal cavity; (b) at least one viscosity-increasing agent; (c) at least one antagonist for the active ingredient having an abuse potential; (d) at least one emetic; (e) at least one colorant serving as an aversive agent, and; (f) at least one bitter substance.
Owner:GRUNENTHAL GMBH
Fuel processing systems, fuel cell systems, and improved feedstocks therefor
Improved feedstocks for hydrogen-producing fuel processing and fuel cell systems, and fuel processing and fuel cell systems incorporating the same. The fuel processing systems include a fuel processor adapted to produce a product hydrogen stream from at least one feed stream containing at least a carbon-containing feedstock and an aversive agent. The fuel processing systems may also include a fuel cell stack adapted to produce an electric current from the product hydrogen stream. The feedstock is at least substantially formed of a hydrocarbon or alcohol. In some instances the feedstock includes methanol and the aversive agent is delivered to a hydrogen-producing region of the fuel processor with the carbon containing feedstock. The aversive agent can include at least one odorant, flavorants regurgitant, and / or dye. In other instances, the feed stream includes water or the feed stream is delivered to a fuel stack that produces and electric current therefrom.
Owner:DCNS SA
Preparation of a quaternary ammonium hydroxide and use thereof for the preparation of a quaternary ammonium salt
InactiveUS20090306429A1Organic compound preparationCarboxylic acid amides preparationBenzoic acidSolvent
The invention relates to a process for the preparation of a quaternary ammonium hydroxide, in particular denatonium hydroxide, and the use thereof for the preparation of a quaternary ammonium salt, in particular of denatonium benzoate or a denatonium fatty acid derivative. Due to its extremely bitter taste, this latter compound is applied in the art as an aversive agent, biocide, antifoulant and flavorant. It is usually prepared from a quaternary ammonium halide in an organic environment, which after isolation and purification is converted to a hygroscopic and unstable hydroxide intermediate, which in turn is immediately converted to the salt of interest in the solvent in which it is prepared. It is now found that these isolation steps can be avoided by performing the reaction at aqueous conditions. This is more straightforwardly and does not require costly precautions to avoid contact while handling. Moreover, the process of the invention allows to produce the quaternary ammonium salt from a lignocaine compound in a one-pot synthesis involving mostly water.
Owner:DISHMAN PHARMA & CHEM LTD +1
Unit dose articles comprising aversive agents and methods related thereto
InactiveUS20170067001A1Organic detergent compounding agentsSurface-active detergent compositionsMedicineWater soluble
Water-soluble unit dose articles that include aversive agents. Processes of forming such unit dose articles, including where a first water-soluble substrate used to form the article includes the aversive agent, and where a second water-soluble substrate used to form the article does not substantially include the aversive agent.
Owner:THE PROCTER & GAMBLE COMPANY
Safety material and system
InactiveUS20140170074A1Prevent accidentalPrevent intentional ingestionUltrasonic/sonic/infrasonic diagnosticsSurgeryButton batteryAversive agent
Compositions and methods for deterring and / or visually identifying oral contact with objects that are hazardous upon oral contact or ingestion are disclosed. The compositions generally comprise a colourant and a carrier and may further comprise an aversive agent, a salivating agent, and / or an emetic. The compositions may be particularly useful for application to batteries, including button cells.
Owner:ENERGIZER BRANDS
Abuse and misuse deterrent transdermal systems
An abuse deterrent and Misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium. The prolonged aversive agent release provides deterrence against extraction of drug from fresh and used patches and serves to prevent accidental misuse of used patches by children. The abuse deterrent and misuse deterrent patch systems can be used for transdermal delivery of therapeutically active agents and particularly those drugs that are highly prone to abuse such as opiate and opioid analgesics and stimulants.
Owner:4P THERAPEUTICS
Water soluble unit dose article comprising an aversive agent
InactiveUS20170066999A1Non-ionic surface-active compoundsOrganic detergent compounding agentsWater solubleAversive agent
The present invention relates to water soluble unit dose articles coated with aversive agent, methods of their manufacture and methods of their use.
Owner:THE PROCTER & GAMBLE COMPANY
Bitter aversive agent and preparation method thereof
InactiveCN105998544AEasy to applyRepair collagen tissueOrganic active ingredientsNervous disorderPreservativeAdditive ingredient
The invention discloses a bitter aversive agent and a preparation method thereof. The aversive agent can consist of a bitter substance carrier, a bitter substance and additives. According to the bitter aversive agent and the preparation method thereof provided by the invention, a fresh aloe original fluid is taken as the bitter substance carrier and is matched with a small quantity of chondroitin, and the bitter substance, assisted by two materials, namely the aloe and the chondroitin, can easily permeate into fingernails and subcutaneous tissues; and after 5min of washing a hand coated with the bitter aversive agent, bitterness is still quite strong. The aversive agent is convenient to coat; the aversive agent is applicable to both the fingernails and skin, and the aversive agent is washing-resistant, wear-resistant, free from preservatives and free from toxic and harmful materials; such allergic substances as calcium oxalate, rheum emodin and the like in aloe leaves are effectively eliminated in a process of preparing the bitter substance carrier, so that the bitter aversive agent is quite suitable for young people and children. The aloe ingredient and the chondroitin are also conducive to the repair of collagen tissues in nail beds and the skin, so as to promote the growth of the nail beds and the repair of the hand skin.
Owner:周国文
Films, compositions, and articles having at least two different aversive agents and methods related thereto
Films, compositions, and articles, for example unit dose articles, having at least two different aversive agents. Methods related thereto.
Owner:THE PROCTER & GAMBLE COMPANY
Paint remover
InactiveCN107641371AAvoid reactionAvoid corrosionChemical paints/ink removersParaffin waxMethyl carbonate
The invention discloses a paint remover. The formula of the paint remover comprises mixed DBE (Dibasic Acid Ester), solvent oil, propylene glycol monomethyl ether, dimethyl carbonate, dichloromethane,methyl alcohol, formic acid microcapsules, paraffin, an emulsifying agent, a thickening agent and an aversive agent. By adopting the technical scheme, the paint remover has the following advantages that: 1, formic acid is subjected to double microencapsulation, so that the formic acid is prevented from corroding an iron tank, and the stability of a product is improved; 2, the surface temperatureof a paint film is reduced by utilizing a rapid vaporization heat absorption characteristic of a propellant, and meanwhile, the paraffin and the thickening agent are added to synergistically retard the volatilization of a low-boiling-point solvent, so that a micro-molecular solvent has enough time to permeate and expand to peel off the paint film; therefore, the paint remover is applicable to improve the paint removal efficiency of the paint on a vertical surface or an inclined surface; 3, the emulsifying agent is added, which helps to clean residual paraffin, so that the adhesion force of a new paint layer is not influenced; 4, the aversive agent is added to prevent the poisoning of people caused by eating the paint by mistake, and construction personnel are reminded to perform good construction protection; 5, the paint remover has the characteristics of flexibility and easiness in use, good atomizing effect and the like.
Owner:GUANGDONG SANVO CHEM IND TECH
Water soluble unit dose article comprising an aversive agent
InactiveUS9988595B2Organic detergent compounding agentsNon-ionic surface-active compoundsWater solubleAversive agent
Water soluble unit dose article comprising detergent or cleaning composition, a water-soluble film surrounding the composition and a particle comprising an aversive agent coated onto the outer surface of the water soluble film, and a process for making the water soluble unit dose article.
Owner:THE PROCTER & GAMBLE COMPANY
Safety material and system
ActiveUS20160211501A1Minimize the possibilityAvoid swallowingUltrasonic/sonic/infrasonic diagnosticsSurgeryButton batteryAversive agent
Compositions and methods for deterring and / or visually identifying oral contact with objects that are hazardous upon oral contact or ingestion are disclosed. The compositions generally comprise a colourant and a carrier and may further comprise an aversive agent, a salivating agent, and / or an emetic. The compositions may be particularly useful for application to batteries, including button cells.
Owner:VICTORIA LINK LTD
Pure beeswax heavy-metal-free food-grade crayon capable of preventing mistaken eating and protecting skin
The invention discloses a pure beeswax heavy-metal-free food-grade crayon capable of preventing mistaken eating and protecting skin and a preparation method thereof, and belongs to the technical fieldof novel coatings. The pure beeswax heavy-metal-free food-grade crayon capable of preventing mistaken eating and protecting skin is prepared from the following components in parts by weight: 3 to 10parts of beeswax, 0.5 to 5 parts of an emulsifier, 0.01 to 1.0 part of a coloring agent, 0.05 to 1.5 parts of an aversive agent, 0.05 to 1.5 parts of a skin care agent, 0.0001 to 0.0006 part of a preservative and 0.1 to 1.5 parts of a filler. According to the invention, the used matrix is food-grade pure beeswax, and the pigment is a food-grade pigment and does not contain heavy metals; and the filler has the effect of improving the writing smoothness, hardness and color rendering of the crayon. The obtained crayon is uniform in pigment mixing, is not sticky to hands, is high in writing smoothness, moderate in hardness, bright in appearance color and good in overall effect.
Owner:ZHUHAI COLLEGE OF JILIN UNIV
Abuse and misuse deterrent transdermal systems
Owner:4P THERAPEUTICS
Preparation method of paint remover
The invention discloses a preparation method of a paint remover. The preparation method comprises the following steps: S1, mixing mixed DBE (Dibasic Acid Ester), propylene glycol monomethyl ether andparaffin, and heating and melting the mixture to obtain a transparent molten paraffin mixture without block-shaped objects; S2, adding solvent oil and dimethyl carbonate into a reacting tank, and heating with stirring; S3, in the state of stirring and keeping the temperature of 36 to 42 DEG C, adding the molten paraffin mixture, dispersing, and mixing uniformly; S4, adding methyl alcohol and dichloromethane, insulating heat, dispersing uniformly, then adding formic acid microcapsules and an emulsifying agent, and dispersing continuously; S5, adding a thickening agent and an aversive agent, insulating the heat, dispersing uniformly, filtering and discharging to obtain the paint remover. The paint remover prepared by adopting the technical scheme has the following advantages that: 1, formicacid is subjected to double microencapsulation, so that the formic acid is prevented from corroding an iron tank, and a hidden danger of corrosion perforation is eliminated; 2, a propellant which canbe vaporized rapidly to absorb heat is optimized to reduce the temperature of a coating surface and cooperates with the paraffin and the thickening agent to retard the volatilization rate, the loss rate and the like of a product.
Owner:广东阜和实业有限公司
Method for controlling pasture stock to forage herbages and livestock
ActiveCN106804535APrevent degradationEfficient use ofAnimal husbandryAgricultural scienceDraft animals
The invention provides a method for controlling a pasture stock to forage herbages and a livestock, and belongs to the technical field of animal husbandry. The method for controlling the pasture stock to forage herbages comprises the following steps: 1, driving the livestock to a pasturing region and pasturing; 2, taking at least one of the following measures on the pasturing region: spraying an aversive agent used for inhibiting the pasture stock to forage herbages in the pasturing region on the herbage regreening period, and spraying a feed attractant used for promoting the stock to forage herbages in the pasturing region on the herbage wilting period. The provided method for controlling the pasture stock to forage herbages controls the pasture stock to evenly forage different-palatability herbages, so that the meadow is well protected while the meadow is efficiently utilized. The invention further provides the livestock obtained through pasture by using the above method for controlling the pasture stock to forage herbages.
Owner:LANZHOU UNIVERSITY
Bubble water and preparation method thereof
The invention discloses bubble water and a preparation method thereof, which belong to the technical field of daily chemistry and toys. The bubble water is prepared from the following raw materials in percentage by weight: 0.5 to 3 percent of foaming agent, 0.05 to 0.1 percent of water treatment agent, 0.05 to 0.5 percent of cationized hydroxyethyl cellulose, 0.05 to 0.5 percent of preservative, 0.05 to 0.3 percent of nipagin ester, 0.001 percent of aversive agent and the balance of water. The bubble water with excellent foaming performance is prepared from the raw materials such as the cationized hydroxyethyl cellulose and the nipagin ester, the bubble water obtained by the invention can be used for blowing more colorful bubbles with more quantity and longer hang time, and compared with the existing bubble water, the bubble water has better application prospect.
Owner:萍乡亨厚新材科技有限公司
Fuel processing systems, fuel cell systems, and improved feedstocks therefor
Improved feedstocks for hydrogen-producing fuel processing and fuel cell systems, and fuel processing and fuel cell systems incorporating the same. The fuel processing systems include a fuel processor adapted to produce a product hydrogen stream from at least one feed stream containing at least a carbon-containing feedstock and an aversive agent. The fuel processing systems may also include a fuel cell stack adapted to produce an electric current from the product hydrogen stream. The feedstock is at least substantially formed of a hydrocarbon or alcohol. In some embodiments, the feedstock includes methanol. In some embodiments, the aversive agent is delivered to a hydrogen-producing region of the fuel processor with the carbon-containing feedstock. In some embodiments, the feed stream further includes water. In some embodiments, the feed stream is delivered to a fuel cell stack that produces an electric current therefrom. In some embodiments, the aversive agent includes at least one odorant, flavorant, regurgitant, and / or dye.
Owner:DCNS SA
Composition and method for treating alcoholism and other substance addictions
InactiveUS20090005367A1Reduce cocaine useAvoid spendingBiocideNervous disorderAlcoholismsBenzodiazepine
Disclosed are pharmaceutical compositions comprising a benzodiazepine, an alcohol aversive agent, and an abuse aversive agent, and methods of use in preventing alcohol or cocaine abuse.
Owner:UNIVERSITY OF CHICAGO
Novel compositions for bitterants
The present invention relates to compositions comprising aversive agent. More specifically, the present invention relates to polymer composite compositions comprising such agents and application thereof.
Owner:UNITED PHOSPHORUS LTD
A method and composition for insect repellency using aversive agent
The present invention relates to a composition comprising aversive agent as insect repellant in agriculture and horticulture. The present invention more particularly relates to Denatonium compound which acts as repellant without harming the life of environmentally useful insects such as honey bees, in addition to reptiles such as lizards, also the mammals such as deer, rodents, nilgai.
Owner:UNITED PHOSPHORUS LTD
Polymer composition with saliva labile aversive agent
For a polymer composition, a polymerizable aversive agent is chemically coupled to a substrate element. The chemical coupling is labile to saliva.
Owner:GLOBALFOUNDRIES INC
Preparation method for elastic polyurethane antifouling paint
InactiveCN104119793AStrong adhesionImprove adhesionAntifouling/underwater paintsPaints with biocidesExtensibilityEnvironmental resistance
The invention relates to a preparation method for an elastic polyurethane antifouling paint. The method includes the steps of: taking 50% of elastic polyester, 20% of an aversive agent, 10% of butyl acetate and 20% of polytetrafluoroethylene, conducting high speed dispersion blending to form an elastic polyester paint; preparing 10% of biuret isocyanate as a curing agent; blending the two groups of materials evenly, performing stabilization for two hours, and then conducting drying at 60DEG C-80DEG C for 30min. The elastic polyurethane antifouling paint provided by the invention has good adhesion, has the same service life with nylon in the marine environment for a long time, and has good extensibility. Biuret isocyanate is a curing agent similar to nylon, can provide good adhesion, and has a stimulating effect on marine adhesion organisms, so that marine adhesion organisms and microorganisms can keep away from a nylon net. The surface slipping agent is non-toxic, and can prevent damage to marine animals. Being environment-friendly and harmless, the paint can keep the original characters of the nylon net, and can achieve the purpose of long-term use.
Owner:上海百川通智能科技有限公司
Films and unit dose articles comprising aversive agents, and uses and methods related thereto
InactiveUS20170066996A1Promote migrationOrganic detergent compounding agentsFlexible coversMedicineAversive agent
Films having an aversive agent, where the films are characterized by a certain average thickness. Unit dose articles including such films. Methods of making and using such films and unit dose articles.
Owner:THE PROCTER & GAMBLE COMPANY
Novel compositions for bitterants
The present invention relates to compositions comprising aversive agent. More specifically, the present invention relates to polymer composite compositions comprising such agents and application thereof.
Owner:UNITED PHOSPHORUS LTD
Spray composition of aversive agent
PendingUS20220127205A1Good curative effectEasy to understandBiocideDead animal preservationBiotechnologyAmmonium compounds
The present invention relates to a composition comprising bittering agent for defense against human or animal attacker. The present invention more particularly relates to a composition comprising denatonium compound for self-defense, method of making and use of said composition as a personal protectant against human or animal attacker.
Owner:UNITED PHOSPHORUS LTD
Chrome-rich grass planting method
InactiveCN107960186AImprove survival ratePromote growthHops/wine cultivationAnimal feeding stuffAversive agentWood pasture
The invention aims to provide a chromium-rich grass planting method. The method comprises the following steps: (1) intercepting the main stalks of the grass as a species of the grass; (2) loosening soil before the stalks are inserted, including deep soil loosing and soil crushing; applying an organic fertilizer after crushing the soil, wherein 0.8 to 1.2 tons of the organic fertilizer is applied per acre; (3) employing a stalk-insertion mode for planting the species of the grass with a depth being 20-25 cm; and after grass cutting planting, watering the grass; (4) when the grass grows to 15-20cm, stocking poultry in grass areas; (5) when the grass grows to 25 to 30 centimeters, spraying an organic chromium solution every other month; (6) spraying an aversive agent to the grass areas during a green returning period of the grass; and spraying a phagostimulant to the grass area during a grass yellowing period; and (7) harvesting the grass once every 45-60 days, watering the grass once after harvesting, and wherein harvesting is carried out 4-5 times per year. The method overcomes the defects of the grass planting in the prior art, has the characteristic of high organic chromium content, and takes consideration to poultry stocking.
Owner:广西博白县玫盛家庭农场
A kind of preparation method of paint remover
ActiveCN107641370BAvoid corrosionEliminate potential safety hazardsChemical paints/ink removersParaffin waxPropanediol
Owner:广东阜和实业有限公司
Sequestering subunit and related compositions and methods
Owner:ALPHARMA INC (US) +1
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