7 results about "Aversive agent" patented technology

An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium. The prolonged aversive agent release provides deterrence against extraction of drug from fresh and used patches and serves to prevent accidental misuse of used patches by children. The abuse deterrent and misuse deterrent patch systems can be used for transdermal delivery of therapeutically active agents and particularly those drugs that are highly prone to abuse such as opiate and opioid analgesics and stimulants.

An aerosol-generating article (100) is provided. The aerosol-generating article (100) comprises an aerosol-generating rod. The aerosol-generating rod comprises an aerosol-generating substrate (12) configured to be heated during use of the aerosol-generating article (100). The aerosol-generating article (100) further comprises a removable wrapper (80), the removable wrapper (80) enclosing at least a portion of the aerosol-generating rod. The removable wrapper (80) is configured to be removed prior to heating the aerosol-generating substrate (12). The removable wrapper (80) comprises at least one flavoring agent, including an aversive agent.

There is provided an aerosol-generating article (10, 100) that generates an aerosol that can be inhaled particularly during heating. The aerosol-generating article (10, 100) includes an aerosol-generating substrate (12), a downstream section (14) extending from the downstream end of the aerosol-generating substrate (12) to the downstream end of the aerosol-generating article (10, 100), and an upstream section (16, 116) extending from the upstream end of the aerosol-generating substrate (10, 100) to the upstream end of the aerosol-generating article (10, 100), the upstream section (16, 116) containing an aversion agent.

An aversive coating and an electrochemical cell having at least a portion of an outer surface coated with the aversive coating are provided to prevent a child from swallowing the electrochemical cell. Compositions and methods for making an electrochemical cell coated with an aversive coating are described, wherein the ratio of aversive gustatory agent to water soluble polymer is such that the aversive coating sufficiently adheres to the electrochemical cell.

An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium. The prolonged aversive agent release provides deterrence against extraction of drug from fresh and used patches and serves to prevent accidental misuse of used patches by children. The abuse deterrent and misuse deterrent patch systems can be used for transdermal delivery of therapeutically active agents and particularly those drugs that are highly prone to abuse such as opiate and opioid analgesics and stimulants.

An aerosol-generating article (100) is provided. An aerosol-generating article (100) comprises an aerosol-generating strip. The aerosol-generating strip comprises an aerosol-generating substrate (12) configured to be heated during use of the aerosol-generating article (100). The aerosol-generating article (100) also includes a removable wrapper (80) that defines at least a portion of the aerosol-generating strip. The removable wrapper (80) is configured to be removed prior to heating the aerosol-generating substrate (12). The removable wrapper (80) includes at least one flavoring agent, the at least one flavoring agent including an aversive agent.