51 results about "Particle analysis" patented technology

The invention relates to the technical field of fluid dynamic testing, in particular to a multiphase jet flow characterization system and method.The system comprises a control unit, a particle image velocity measurement unit, a phase Doppler particle analysis unit, a laser Doppler velocity measurement unit and a planar laser-induced fluorescence unit, and the particle image velocity measurement unit, the phase Doppler particle analysis unit, the laser Doppler velocity measurement unit and the planar laser-induced fluorescence unit are connected with the control unit; the particle image velocity measurement unit is used for measuring a macroscopic velocity field; the phase Doppler particle analysis unit is used for measuring microdynamics information; the laser Doppler velocity measurement unit is used for measuring a velocity profile; the planar laser-induced fluorescence unit is used for measuring a concentration field of a target component in the multiphase jet flow; the control unit is used for receiving measurement results of all the units, conducting fusion processing on the measurement results and outputting characterization results. The multi-phase jet flow can be comprehensively represented, multi-dimensional physical information can be synchronously obtained, and the solid-liquid-gas interphase coupling and phase change mechanism of the multi-phase jet flow can be accurately revealed.

The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

A computer-implemented method for characterizing a heterogeneous material comprising dispersed components, particularly particulate components, dispersed within a continuous phase of a condensate comprises the steps of: a) providing or selecting a sample of the heterogeneous material to be analyzed; b) acquiring at least one digital image of the sample by a camera of a computing device, particularly a mobile computing device, or by a camera connected to a computing device, particularly a mobile device, and / or by reading into the computing device at least one digital image previously recorded by a stand-alone camera; and c) determining the following characteristics: size parameters, particularly granularity parameters, shape parameters, and the like, determined by image analysis in the at least one digital image. performing image analysis, in particular image particle analysis, of at least one digital image to extract one or more of the following characteristics: particle shape parameters, in particular particle distribution, orientation parameters, in particular particle orientation parameters, surface parameters, in particular particle surface parameters, roughness parameters, in particular particle roughness parameters, packing density, uneven distribution parameters, color, and / or area fraction of components, in particular particulate components; and / or area fraction of continuous phases identified by image analysis in the at least one digital image; d) making one or more of the extracted characteristics in step c) available via a user interface, via a machine interface, and / or on a data storage medium.

The utility model discloses a building foundation soil particle analysis and detection device for engineering supervision, and belongs to the field of building construction.The building foundation soil particle analysis and detection device comprises a frame and a motor, four feeding pipes are fixedly installed on the inner wall of the frame, a power output shaft of the motor is fixedly connected with a rotating rod, and a connecting plate is fixedly installed on the outer edge of the rotating rod; a convex groove is formed in the top of the connecting plate, a convex block is connected to the inner wall of the convex groove in an inserted mode, a screening bin is fixedly installed on the outer side of the convex block, a discharging pipe fixedly communicates with the bottom of the screening bin, and a control valve is rotationally installed on the inner wall of the discharging pipe. By arranging the screening bin, the discharging pipe, the electronic weighing bin, the vibration motor and the filter screen, automatic detection is achieved, the detection time is remarkably shortened, manual intervention is reduced, the operation difficulty is lowered, the detection efficiency and accuracy are improved, the overall design is compact, carrying is easy, the device is particularly suitable for rapid detection on a construction site, and the working efficiency is greatly improved.

The invention relates to a particle analysis system, an information processing method, and a computer readable storage medium. A particle analysis system includes: a light detector that acquires light generated by irradiating particles with excitation light; and an information processing unit that outputs a spectrogram including spectral information of an autofluorescence population specified in a two-dimensional map of measurement data, each measurement data corresponding to the acquired light, and spectral information of the measurement data corresponding to the autofluorescence population specified in the two-dimensional map. And the information processing unit records spectral information of the autofluorescence population as an autofluorescence reference spectrum in the fluorescence separation process.

For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.

This invention discloses a flow cytometer for aggregate particle analysis that enhances the scattering of small particles by tilt angle, comprising a fluid flow system, an optical system, and a control system. The optical system includes an excitation optical path, a forward detection optical path, and a lateral detection optical path. The excitation optical path includes a first laser, a second laser, a reflector, and a quartz cup detection cell. The reflector is used to reflect the first laser beam directly emitted by the first laser. The forward detection optical path includes a forward divergence lens group, a forward divergence bandpass filter, and a forward divergence detector arranged in sequence. The lateral detection optical path includes a lateral objective lens, multiple dichroic mirrors, an SSC filter and an SSC detector, and a VSSC filter and a VSSC detector. This invention utilizes tilt angle scattered light signals to extend the detection capability of existing flow cytometers for smaller submicron particles, further advancing the existing 200nm particle size detection limit to the 80nm particle size range.

A particle analysis device (100) comprises: a light source that emits excitation light (EL1) including light with wavelengths of 400 nm or less; a lens structure (41) that concentrates the excitation light (EL1) onto a predetermined position (51s) in a flow path (53); a detection unit (7) that detects light (FL) radiated from a particle (51) flowing through the predetermined position by the particle being excited by the excitation light (EL1); and a processing unit (120) that processes detection data acquired by the detection unit (7). The lens structure (41) comprises a plurality of lenses (411) arranged along the optical axis of the excitation light (EL1), and a lens frame (412) that holds the plurality of lenses (411), and the position within the lens frame (412) of at least one lens (G12) among the plurality of lenses (411) is determined by the one lens being brought into contact with a lens adjacent thereto.

Methods for determining parameters of particles in a flow stream from scattered light (e.g., in a particle analyzer of a flow cytometer) are described. Methods according to certain embodiments include illuminating particles in a flow stream with a frequency-modulated laser beam modulated at a reference frequency, detecting scattered light from the particles with a photodetector, generating a frequency-encoded data signal from the detected scattered light, synchronizing the frequency-encoded data signal to the reference frequency, and determining one or more parameters of the particles based on the synchronized frequency-encoded data signal. Systems for practicing the subject methods and non-transitory computer-readable storage media having instructions for practicing the subject methods are also provided.

Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and / or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.

A microfluidic device for particle analysis, such as immunophenotyping, includes a plurality of microfluidic channels for the passage of a particle-laden fluid flow, a plurality of dedicated impedance sensors for generating impedance signals relative to each microfluidic sensor. The impedance sensors are CODES Coulter sensors, each having a distinct coded sequence for generating mutually orthogonal signals. The system uses a multi-frequency excitation signal for driving the Coulter sensors, such that the Coulter sensors generate multi-frequency impedance signals. The system outputs the multi-frequency signals of the plurality of impedance sensors as a single multi-frequency multiplexed signal, which is subsequently separated into a plurality of single-frequency multiplexed signals, which are then demodulated into single-frequency component signals corresponding to each of the Coulter sensors.

Particle collection device for collecting particles from surfaces for particle analysis as part of a technical cleanliness test of test specimens, wherein the particle collection device comprises suction air guide means (01) to guide a suction air flow and to separate particles from the suction air flow via at least one particle collection unit (30), wherein the suction air guide means (01) comprise at least two adjacent line sections (02, 03, 06) which form the line of the suction air line via at least one transition (09), wherein at least one first line section (02) has an outer flange (08), and wherein a clamping means (04) is provided associated with the transition (09), which comprises a movable clamping fork (07) which can be moved into a locking state and a release state by a clamping movement, wherein in the release state the line sections (02,03) are unconnected and separable and wherein, in the secured state, the clamping fork (07) exerts force on the outer flange (08) of the first conductor section (02) and thus presses the first conductor section (02) against the second conductor section (03), wherein on an underside (10) of the clamping fork (07) facing the outer flange (08), an elongated, elastically deformable spring element (15) is arranged in end regions (13) of two fork tines (14) of the clamping fork (07).

This invention provides a means to obtain more clinically useful information when analyzing particles contained in blood samples using metachromatic positive dyes. In a particle analysis method for analyzing particles contained in blood samples, particles are stained with a metachromatic positive dye; the stained particles are irradiated with light; the intensity of a first fluorescence from the stacking component of the metachromatic positive dye and the intensity of a second fluorescence from the embedded component of the metachromatic positive dye are measured, the first and second fluorescence being emitted by each particle contained in the blood sample; the intensities of the first and second fluorescence emitted by each particle are normalized according to the size of each particle to obtain the fluorescence concentration of each of the first and second fluorescence in each particle; in a two-dimensional plot of the normalized fluorescence concentrations, each particle is clustered into multiple particle clusters, including at least two of erythrocyte clusters, platelet clusters, and nucleated cell clusters; and a histogram is created where the intensity of the first fluorescence is a histogram of the RNA amount of the class and the intensity of the second fluorescence is a histogram of the DNA amount of the class included in at least one of the multiple particle clusters.

To provide a technique capable of improving reliability of data analysis.SOLUTION: The present technology includes a storage unit that stores event data including light intensity data obtained by irradiating one particle of a plurality of particles with light, and a processing unit that performs processing on a plurality of pieces of event data acquired from the plurality of particles, wherein the storage unit stores a flag that is given when the light intensity data exceeds a threshold value, the processing unit performs processing on the plurality of pieces of event data other than the light intensity data to which the flag is assigned, in response to an instruction to exclude the light intensity data to which the flag is assigned.SELECTED DRAWING: Figure 1

In analysis of a particle by a PTA method, in order to enable each particle to be analyzed for each type while suppressing increase in size and cost of a device even in a case where excitation wavelengths of fluorescent markers or particles having property of autofluorescence overlap each other, a light irradiation unit (2) that irradiates a sample emitting fluorescence of a plurality of colors with excitation light, one or a plurality of filters (5) that transmits the fluorescence of the plurality of colors while cutting off excitation light, an imaging unit (3) having color identification ability to image fluorescence passing through the filter (5), and an analysis unit (43) that obtains a diffusion rate due to Brownian motion of a particle included in a sample from image data of fluorescence obtained by the imaging unit (3) and analyzes physical property of the particle are included.

The invention relates to a training data set acquisition method and a microscopic particle analysis method, and the method comprises the steps: extracting a plurality of particles from an original training data set with labels as seeds, removing a background through an image segmentation method, and storing the background as a transparent channel image; gaussian blur processing is carried out on an original image, and a diversified background image pool is constructed; and placing a plurality of extracted particles in various backgrounds through a plurality of rules to obtain a plurality of combinations, and generating new image data with labels. And mixing the generated new image data with the original training data set in proportion to form a mixed data set. According to the method, a large amount of labeled data can be obtained through expansion of a small amount of original labeled data, and the generated new image data is formed by crossed combination of particles and backgrounds, so that the sample quality is high, the problem of high cost of deep learning labeling in the field is solved, and the industrial application cost is greatly reduced.

The present invention provides a material testing machine and a particle analysis device, which can improve the workability of the operator. The tensile testing machine (1) includes: a testing machine body (2) for performing material tests; a corresponding storage unit (541) for establishing and storing a specific word (KW) and an instruction information (CM) for the testing machine body (2) in a corresponding manner; a voice receiving unit (534) for receiving voice from the user; an extraction unit (535) for extracting the specific word (KW) from the voice through voice recognition processing; a decision unit (536) for determining the instruction information (CM) corresponding to the specific word (KW) extracted by the extraction unit (535) with reference to the corresponding storage unit (541); and an instruction unit (537) for outputting the instruction information (CM) determined by the decision unit (536) to the testing machine body (2).

The invention discloses a method for correcting a densimeter method by using a nylon filter cloth wet screen analysis method, and relates to the technical field of particle analysis in soil mass engineering properties. And for the fine-particle soil body with the particle size smaller than 0.075 mm, based on the particle size division standard of the wet screen analysis method, synchronous adjustment of the particle size of the densimeter method is achieved by adopting an interpolation method, and verification is conducted. The principle is clear, the calculation process is completely programmed, more accurate gradation is obtained, the repeatability is high, the stability is high, and the reliability is high; the defects of time consumption, labor consumption, high cost and the like caused by comprehensive popularization of a wet screen analysis method are avoided, the advantages of simplicity and convenience in operation and good continuity of a densimeter method are reserved, and meanwhile, the precision of fine-grained soil particle analysis is improved; densimeter method system errors caused by Stokes law hypothesis, temperature influence, reading errors and other factors are effectively optimized, so that the finally obtained grain composition curve is closer to the real distribution of soil samples, and the problem of low data accuracy of the densimeter method, which puzzles engineering practice for a long time, is solved.

A main objective of the present technology is to improve separation performance of a fluorescence spectrum.The present technology provides a particle analysis system including: a light irradiation unit including at least one first light source that emits light with a wavelength equal to or greater than 350 nm and at least one second light source that emits light with a wavelength less than 350 nm; and a processing unit configured to perform unmixing processing on light data obtained by irradiating particles with light by the light irradiation unit. In addition, the present technology also provides an information processing method including an unmixing processing step of performing unmixing processing on light data obtained by irradiating particles with light by a light irradiation unit including at least one first light source that emits light with a wavelength equal to or greater than 350 nm and at least one second light source that emits light with a wavelength less than 350 nm.

Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. A contrast pattern for autofocusing is provided on the flowcell, for example at an edge of a rear illumination opening. The image processor assesses focus accuracy from pixel data contrast. A positioning motor moves the microscope and / or flowcell along the optical axis for autofocusing on the contrast pattern target. The processor then displaces microscope and flowcell by a known distance between the contrast pattern and the sample stream, thus focusing on the sample stream. Blood cell images are collected from that position until autofocus is reinitiated, periodically, by input signal, or when detecting temperature changes or focus inaccuracy in the image data.

The utility model provides a device for assisting a wafer transfer box in oscillation. The device comprises an outer frame; the embedded box is rotatably connected to the interior of the outer frame, and the embedded box is used for accommodating the wafer conveying box and is fixedly connected with the wafer conveying box; the telescopic air cylinder is located in the outer frame and located on the lower side of the embedded box. The telescopic air cylinder is provided with a telescopic rod which abuts against the lower surface of the embedded box. The embedded box has an oscillation track which oscillates relative to the outer frame based on the telescopic motion of the telescopic rod. The accuracy of the oscillation frequency of the embedded box in a liquid particle counter method after the wafer conveying box is cleaned can be improved, the manual operation error of an oscillation operator is eliminated, the standardization and repeatability of particle analysis testing are improved, the cleaning cleanliness of the wafer conveying box is improved, the defect caused by the pollution of the wafer conveying box to the wafer is avoided, and the production efficiency of the wafer conveying box is improved. And the yield of the wafer is improved.

The application provides a vertical shaft plane grinding wheel characteristic measuring device and a dynamic abrasive particle analysis method, a first grinding wheel surface three-dimensional digital model is obtained by performing one-time spatial reconstruction on the macro-micro structure characteristics of the grinding wheel surface according to the measurement data; a simulation experiment on the abrasive particle motion track is performed based on the first grinding wheel surface three-dimensional digital model and the grinding process parameters; the dynamic abrasive particle is determined according to the interference state of the abrasive particle and the workpiece; the macro-micro structure characteristics of the grinding wheel surface are subjected to secondary spatial reconstruction after filtering out the characteristics of the non-dynamic abrasive particle, and a second grinding wheel surface three-dimensional digital model is obtained; the two three-dimensional digital models are subjected to discrete processing respectively, each micro-element obtained through the discrete processing is analyzed, and the correlation between the dynamic abrasive particle distribution and the dynamic abrasive particle probability and the macro-micro structure characteristics of the grinding wheel surface and the grinding process parameters is established according to the analysis result, so that the solution of the dynamic abrasive particle distribution and the dynamic abrasive particle probability of the grinding wheel surface under different grinding conditions is realized.

The invention provides a preparation method of a salt-containing structural soil model, and belongs to the technical field of research and development of building construction materials, and the salt-containing structural soil is prepared from the following materials: a soil material, kaolin, cement, urea and salt. A specific gravity test, a particle analysis test and a limit moisture content test need to be carried out on the soil material, and a specific gravity test needs to be carried out on kaolin and cement. The method comprises the following steps: proportioning urea, the dried soil material, kaolin and cement in proportion according to a specific gravity result, layering, putting into a self-made square mold, compacting, putting a sample into a constant-temperature water bath kettle, curing, taking out the sample after the urea is fully dissolved, putting into a drying oven, drying, and saturating by using saline water with a certain concentration. The invention provides a simple and effective preparation scheme for artificially preparing the salt-containing structural soil model, and a reliable basis can be provided for design and construction of buildings in a salt-containing structural soil area.

This invention discloses a dynamic image analysis and measurement method and system for cassiterite mineral particles, specifically relating to the field of industrial vision analysis technology. It addresses the problem that existing methods struggle to accurately distinguish particle motion states and separate motion trails in dynamic flow fields, leading to inaccurate segmentation, tracking, and parameter measurement. By acquiring continuous frame images and extracting flow velocity characteristics of the flow field region, the method determines cross-frame displacement trends based on the overlap of neighboring pixel grayscale distribution and flow velocity characteristics. It extracts the stability of candidate particle contour morphology and performs matching verification. For matched particles, it constructs a flow velocity field constraint range and obtains a motion vector field. Combining the motion vector amplitude corresponding to the cassiterite mineral density, it uses density clustering to distinguish cross-frame displacement from independent multi-particle motion. High-speed moving particles are selected, and inter-frame grayscale gradient difference is used to separate motion trails from the true contour. Based on the motion type and the true contour, it completes target segmentation, contour tracking, and parameter measurement, improving the accuracy of particle analysis under dynamic conditions.

The embodiment of the present application provides a kind of spectrum detector and particle analyzer, including base, positioning plate, photoelectric detection component, multiple circuit board components and power board, positioning plate is fixed on the top side of base and is spaced apart from base along the top-bottom direction of spectrum detector;Multiple circuit board components are at least electrically connected with photoelectric detection component, the bottom end of each circuit board component is fixed on the base, and the top end is fixed on the outer periphery of positioning plate, to realize positioning by positioning plate and base, the top end of circuit board component is provided with multiple electric connection pins;Power board is provided with multiple electric connection sites, when power board is matched with positioning plate along top-bottom direction, the electric connection pin of each circuit board component is inserted into multiple electric connection sites.The spectrum detector of the present application, positioning plate and base accurately solidify the spatial position of each circuit board component, as long as the positioning connection of positioning plate and power board is realized, the plug-in cooperation of power board with multiple circuit board components can be realized, and it is simple and convenient to operate.

The invention discloses a microscopic image particle analysis method and system based on a dynamic window, relates to the technical field of microscopic images, and outputs a corresponding relation between a physical length and a pixel length based on the combination of a microscopic image and a corresponding image scale. Determining a corresponding sampling region by combining the division of the microscopic image; the dynamic window is introduced into the sampling area, the corresponding mark is presented in the sampling area, and the sampling area and the dynamic window are combined, so that the marking accuracy of the sampling area is improved. Corresponding deletion events and marking events are determined based on the operation of the new sampling area, unified deletion of all particle marking data in the coordinate range of the new sampling area is presented in the deletion events, and in the marking events, starting points and ending points of particle line segments completely fall into the new sampling area; and based on the fact that the corresponding diameter length is greater than the minimum diameter threshold value, the particles are subjected to multi-stage analysis, and the accuracy of particle line segments is ensured.

This invention discloses a non-clogging, multi-stage microplastic particle grading and sorting device based on centrifugal microfluidics, belonging to the field of microplastic particle analysis technology in aquatic environments. It includes one or more analysis units arranged around the centrifugal axis of a centrifugal microfluidic chip. Each analysis unit consists of a digestion module and a microplastic particle size sorting and capture module. The microplastic particle size sorting and capture module includes an enhanced liquid chamber, a particle size sorting zone, a squeezing microfluidic channel, a gradient particle size separation zone, and a waste liquid chamber. This invention utilizes the coupling of centrifugal force and Coriolis force, along with an anti-angle array, to classify microplastics of different particle size ranges. The angle between the centrifugal force direction and the anti-angle array is greater than 90°, achieving a non-clogging effect on the array, resulting in a high microplastic particle capture rate and small error. Furthermore, centrifugal force is used to achieve fine sorting of microplastics within different particle size ranges based on size, improving the problem of small particle size sorting range for microplastics on a single chip. This invention also discloses a non-clogging, multi-stage microplastic particle detection method based on centrifugal microfluidics, which can rapidly and accurately sort and detect target microplastics of different particle sizes and compositions, offering significant advantages in rapid on-site detection of microplastics.

The present invention provides technology capable of individually discriminating the states of a plurality of independent particles.　Provided is a particle analysis system comprising: a flow path through which particles flow; a plurality of detection optical systems which are disposed at positions facing each other across the flow path and which have different focal planes in the flow path; and a plurality of detection units which each include a detector that detects light derived from a corresponding detection optical system.

The present application provides a kind of batch production process of bare spot repair area marine substrate of sea grass bed, belong to the field of ecological restoration of sea grass bed, including the following steps, S1: bare spot repair area marine substrate sampling and particle analysis experiment;S2: marine substrate external purchase soil source detection and purchase;S3: external purchase soil source screening and mixing;S4: sampling detection after mixing;S5: bagging and preservation.The present application provides a batch production process of marine substrate, simple and easy to operate, low operation requirement, can rebuild suitable substrate environment for sea grass bed in bare spot repair area of sea grass bed, provides good substrate source for large-scale repair of sea grass in bare spot repair area of sea grass bed.

The utility model discloses soil particle analysis equipment for water erosion detection, which comprises a base and is characterized in that a soil analysis equipment main body and a screening mechanism are mounted on the upper surface of the base, and a driving mechanism for driving the screening mechanism to swing up and down and back and forth is mounted on the upper surface of the base; a pressing mechanism for driving soil particles in the screening mechanism to shake is installed at the outer end of the screening mechanism, the screening mechanism comprises a screening box, three sets of fixing plates are slidably connected to the interior of the screening box, elastic cloth is installed in the fixing plates, and a filter screen is installed in the elastic cloth; when the driving mechanism is pushed to pull the screen box to swing back and forth at the upper end of the base, the screen box is pulled to swing up and down at the upper end of the base, so that the driving mechanism accelerates to drive soil particles in the screen box to be screened, and the time consumed by a worker when the device is used for analyzing the soil particles is shortened; therefore, the practicability of the device is improved.