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2results about How to "Improve constipation" patented technology

Guanylate cyclase-c activator peptide and uses thereof

PendingCN122356212Aactivation activityGood water solubilityCyclasePharmaceutical Substances
This invention discloses a guanylate cyclase-C (GC-C) activating peptide and its applications, belonging to the field of bioactive peptide technology. The amino acid sequence of the GC-C activating peptide is PFPGPIPN. The GC-C activating peptide of this invention can significantly activate GC-C activity, increasing intracellular cGMP levels. Furthermore, the GC-C activating peptide of this invention can alleviate constipation and abdominal pain symptoms in mice, thereby effectively preventing or improving irritable bowel syndrome (IBS). Therefore, the GC-C activating peptide provided by this invention has advantages such as high activity, safety and non-toxicity, and good water solubility. It can be used as a candidate molecule for alternative or adjuvant drugs in the clinical treatment of IBS, and also as a health product or food to improve constipation or abdominal pain.
Owner:NORTHWEST A & F UNIV +1

Medical multifunctional inflatable mattress for prone position

ActiveCN224207013UReduce overall body stressRelieve symptoms of chest tightness and breathlessnessChiropractic devicesNursing bedsPhysical medicine and rehabilitationCotton pad
The utility model discloses a medical multifunctional prone position inflatable mattress, which relates to the technical field of medical mattresses and comprises an air cushion bed main body. An air cushion cotton cushion is installed on the upper surface of the air cushion bed body, an air pump is installed on the rear surface of the air cushion bed body, an air bag partition module is installed on the left side of the upper surface of the air pump, a pressure regulator is arranged on the right side of the upper surface of the air pump, and an inflation connector is arranged on the right side surface of the air cushion bed body. Compared with an existing common multifunctional medical prone-position mattress, the medical prone-position multifunctional inflatable mattress has the advantages that the first wedge-shaped air bag and the second wedge-shaped air bag are arranged, so that the medical prone-position multifunctional inflatable mattress is convenient to use; the body position of a patient can be assisted to turn over by 15-30 degrees by independently inflating and pressurizing the wedge-shaped air bag I and the wedge-shaped air bag II, so that the pressure of the whole body of the patient is relieved, the chest distress and suffocation symptoms of the patient are relieved and the constipation incidence rate is reduced on the basis that the traditional position of the patient after the spinal cord and spinal column operation is kept.
Owner:PEKING UNIVERSITY THIRD HOSPITAL (THE THIRD CLINICAL MEDICAL SCHOOL OF PEKING UNIVERSITY)