206 results about "Cetylpyridinium chloride" patented technology

Antimicrobial compositions and methods are disclosed. The antimicrobial compositions are particularly useful in providing antimicrobial capability to a wide-range of medical devices. In one aspect the invention relates a UV curable antimicrobial coating comprising a UV curable composition comprising an oligomer, a momoner, and a photoinitiator which are together capable of forming a UV curable polymer composition. The compositions include rheology modifiers as necessary. The compositions also include antimicrobial agents, which may be selected from a wide array of agents. Representative antimicrobial agents include cetyl pyridium chloride, cetrimide, alexidine, chlorexidine diacetate, benzalkonium chloride, and o-phthalaldehyde.

This invention encompasses an oral composition for treating or preventing dry mouth with following benefits: antibacterial / anti-fungal efficacy, low irritancy, and moisture retention. The compositions can be a toothpaste, a mouth rinse or a spray and include one or more non-ionic surfactants, as foaming agents, one or more broad spectrum anti-microbial ingredient, such as chlorhexidine and cetylpyridinium chloride, and one or more oral surface adhesive polysaccharides that can encage cationic actives to help the deposition and retention of the agents onto oral surfaces and thus provide antimicrobial efficacy.

Precipitated silica product having low surface area and enhanced flavor compatibility. The precipitated silica product is especially well-adapted for use in dentifrices containing cetylpyridinium chloride, which do not attach to the low surface area silica product in a meaningful level and thus remain available for antimicrobial action. Processes for making the low surface area silica product are also provided.

The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.

Disclosed are oral care compositions effective to control mouth and breath malodour comprising in a pharmaceutically acceptable carrier, a combination of an antibacterial agent and a deodorizing or odor-neutralizing agent comprising a compound having the structurewherein R1, R2, R3, and R5 may be identical or different, each representing H, a linear or branched C1-C6 alkyl or alkenyl, phenyl, —OH or —ORa; R4 is —OH, —ORa, phenyl, or a linear or branched C1-C6 alkyl or alkenyl; and Ra is phenyl or a linear or branched C1-C6 alkyl or alkenyl. The odor-neutralizing agent may further comprise one or more of an additional odor-neutralizing compound selected from α-damascenone, α-isomethylionone, α-ionone, β-ionone, pulegone, piperitone, carvone, coenzyme Q10 or cinnamaldehyde.The antibacterial agent may comprise one or a mixture of a quaternary ammonium compound selected from cetylpyridinium chloride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide; metal ions such as stannous, zinc or copper; chlorhexidine; triclosan; triclosan monophosphate; or selected essential oils.

An improved ophthalmic composition comprising an anionic polymeric substance, such as Hyaluronic Acid and / or Carboxymethylcellulose, in combination with any of various cationic monomeric or dimeric antimicrobial agents, such as Cetylpyridinium Chloride and / or Alexidine Dihydrochloride, wherein said compositions provide additional comfort and biocompatibility with lenses without significantly affecting the antimicrobial efficacy of the antimicrobial agent and without therefore requiring a substantially increased concentration of the agent such as that could expose contact lens wearers to increased levels of the disinfecting agent. Solutions according to the present invention may be used for effective multipurpose contact lens disinfection compositions, lens packaging solution compositions, and / or eye drops such as rewetters and tears.

Disclosed are oral care mouth rinse compositions formulated as stable oil-in-water emulsions comprising:(a) at least about 0.025% by weight of a quaternary ammonium antimicrobial agent,(b) at least about 0.05% by weight of an essentially water-insoluble volatile oil, and(c) at least about 50% by weight water,wherein the emulsion comprises oil droplets having an average mean particle size of about 350 nm or less.Examples of quaternary ammonium antimicrobial agent include cetylpyridinium chloride (CPC), tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide.

The invention discloses an alcohol-hydrothermal method for preparing anthoid BiVO4. The method comprises the following steps of: under a stirring condition, adding cetylpyridinium chloride as a surface active agent to a mixed solution, wherein the volume ratio of ethanol to glycol to concentrated HNO3 (the concentration is 67 percent) in the mixed solution is 12:12:1, the concentration of the cetylpyridinium chloride is 0.48mol / L; adding Bi(NO3)3.5H2O and NH4VO3 according to the molar ratio of Bi(NO3)3 to NH4VO3 to nitric acid is 1:1:4 after dissolving; adding NaOH powder to control the pH value of the solution to 3-7; transferring the mixed solution into a stainless steel self compression kettle (the volume filling degree is 63 percent) with a polytetrafluoroethylene lining and putting the stainless steel self compression kettle in a thermostat for treating for 12h at a temperature of 100 DEG C; taking out the stainless steel self compression kettle and cooling to room temperature; and after drying an obtained product for 12h at a temperature of 60 DEG C, obtaining BiVO4 micron particles with monoclinic scheelite structures. Bismuth orthovanadate crystals with specific appearances obtained by the method have good application prospects in the field of photocatalysis, electrode materials, pigment, ionic conductive ceramics, and the like.

An antimicrobial application system is disclosed, comprising an antimicrobial application unit and a recycle unit. An initial, dilute antimicrobial composition is prepared. The composition is provided to the antimicrobial application unit and applied to work pieces, such as raw poultry. After application to the work pieces, the composition is returned to the recycle tank. The concentration of the antimicrobial in the recycle tank is monitored, and additional antimicrobial is automatically added if the concentration of the antimicrobial in the composition falls below a desired amount. The composition is periodically diverted to a capture tank, and the antimicrobial is selectively removed from the composition. The removed antimicrobial and remaining composition are then disposed of in appropriate manners. The antimicrobial is preferably a quaternary ammonium compound, is more preferably an alkylpyridinium chloride, and is most preferably cetylpyridinium chloride.

An antimicrobial application system is disclosed, comprising an antimicrobial application unit and a recycle unit. An initial, dilute antimicrobial composition is prepared. The composition is provided to the antimicrobial application unit and applied to workpieces, such as raw poultry. After application to the workpieces, the composition is returned to the recycle tank. The concentration of the antimicrobial in the recycle tank is monitored, and additional antimicrobial is automatically added if the concentration of the antimicrobial in the composition falls below a desired amount. The composition is periodically diverted to a capture tank, and the antimicrobial is selectively removed from the composition. The removed antimicrobial and remaining composition are then disposed of in appropriate manners. The antimicrobial is preferably a quaternary ammonium compound, is more preferably an alkylpyridinium chloride, and is most preferably cetylpyridinium chloride.

The present invention provides a flavoured product comprising four or more flavour materials having antimicrobial properties and selected from the group comprising nonanol, decanol, nonanal, decanal, amyl propionate, anethole synthetic, anisic aldehyde, basil oil, benzyl benzoate, benzyl butyrate, benzyl formate, camomile oil, cinnamic aldehyde, cis-3-hexenol, clove bud oil, damascone, ethyl acetoacetate, eucalyptus oil, ginger, isoamyl acetate, menthol laevo, methyl cinnamate, methyl salicylate, orange oil, rosemary oil, tarragon, Tea Tree oil, and peppermint oil; and one or more antimicrobial agents selected from the group comprising triclosan, pyrophosphates, zinc salts, cetylpyridinium chloride, parabens, stannous salts, sodium dodecyl sulphate, chlorhexidine, copper salts, strontium salts, peroxides and sanguinarine.

A toothpaste formulation is disclosed which comprises hydrogen peroxide; and cetylpyridinium chloride, and wherein the hydrogen peroxide and the cetylpyridinium chloride have been combined in the toothpaste formulation for not more than about seven minutes prior to administration to an individual. A mouth rinse formulation is disclosed which comprises hydrogen peroxide; and cetylpyridinium chloride, and wherein the hydrogen peroxide and the cetylpyridinium chloride have been combined in the mouth rinse formulation for not more than about seven minutes prior to administration to an individual. A whitening gel formulation is disclosed which comprises hydrogen peroxide; and pH adjuster, and wherein the hydrogen peroxide and the pH adjuster have been combined in the whitening gel formulation for not more than about seven minutes prior to administration to an individual. The toothpaste formulation, the mouth rinse formulation, and the whitening gel formulation further comprise lycopene.

The invention belongs to the field of daily necessities and in particular discloses liquid toothpaste and a preparation method thereof. The liquid toothpaste is prepared from xylitol, vitamin C, cetylpyridinium chloride, sodium fluoride, natural betaine, sodium phytate, traditional Chinese medicine extracting solution, lauryl sodium sulphate, sodium lauroyl sarcosine, glycerol, sorbitol, silica, essence, a freshener, antiseptic, a sweetening agent, edible gum and water. The toothpaste is in a liquid state, so that active ingredients in the liquid toothpaste product can smoothly reach each surface of an oral cavity, quickly go deep into gaps of teeth and cover the whole teeth, the traditional Chinese medicinal extracting solution and cetylpyridinium chloride in the formula can be matched with other components, sterilization can be effectively carried out, bacteria growth can be inhibited, dental plaque can be eliminated, caries can be prevented, gingival and periodontal problems such as gingival bleeding, gingival pain, gingival swelling and ozostomia can be effectively solved, the oral cavity is protected, and teeth are whitened and healthy.

New liquid compositions are described for the relief of the xerostomia and the treatment of associated disorders, in which the compositions contain: a) saline saliva substitute agents selected from the group consisting of sodium chloride, potassium chloride, sodium bicarbonate, monobasic potassium phosphate, and dibasic phosphate potassium; b) saliva production stimulation agents selected from the group consisting of citric acid or its alkali metal salts and malic acid or its alkali metal salts; c) oral antiseptics selected from the group consisting of triclosan, chlorhexidine and its salts, benzalkonium and its salts, and cetylpyridinium chloride; d) anticariogenic agents selected from the group consisting of fluoride sodium, sodium monofluorophosphate, and xylitol; and e) oral mucosa protective agents selected from the group consisting of vitamin E acetate, panthenol, dipotassium glycyrrhizinate and extracts of aloe vera.The aforementioned compositions are presented in the form of mouthwashes, sprays, oral gels, and toothpastes.

The invention discloses an oil gas field exploitation used compound inhibitor and the preparation method. The compound inhibitor contains imidazolinyl organic phosphate, 2 - N-acid butyrate -1, 2, 4-tricarboxylic acid, thiourea, cetylpyridinium chloride. The mixture proportions of all constituents by weight can meet the specified contents of all active substances. The preparation method is that the 2 - N-acid butyrate -1, 2, 4 - tricarboxylic acid is added into imidazolinyl organic phosphate; thiourea is added into and dissolved into water; the solutions obtained by sub-steps are mixed together and are added into the cetylpyridinium chloride; after evenly stirring for 50-90 minutes and keeping the temperature rang within 15-45 DEG C, the inhibitor of the invention is produced. The compound inhibitor uses multifold medicaments for synergia, can prevent scale formation, can kill bacteria or inhabit bacteria from growing with less usage, can be applied to wide range, and can perform excellent efficiency under complex water quality condition.

A cationic-compatible inorganic particulate comprising silica substantially coated with a non-ionic surfactant, such as an ethoxylated hydrogenated hydrocarbon oil. Compositions comprising the cationic-compatible particulate and a cationic active, such as cetyl pyridinium chloride or an ethyl lauryl arginine ester, are also provided.

New liquid compositions are described for the relief of the xerostomia and the treatment of associated disorders, in which the compositions contain: a) saline saliva substitute agents selected from the group consisting of sodium chloride, potassium chloride, sodium bicarbonate, monobasic potassium phosphate, and dibasic phosphate potassium; b) saliva production stimulation agents selected from the group consisting of citric acid or its alkali metal salts and malic acid or its alkali metal salts; c) oral antiseptics selected from the group consisting of triclosan, chlorhexidine and its salts, benzalkonium and its salts, and cetylpyridinium chloride; d) anticariogenic agents selected from the group consisting of fluoride sodium, sodium monofluorophosphate, and xylitol; and e) oral mucosa protective agents selected from the group consisting of vitamin E acetate, panthenol, dipotassium glycyrrhizinate and extracts of aloe vera. The aforementioned compositions are presented in the form of mouthwashes, sprays, oral gels, and toothpastes.

The invention discloses a Mannich base metal iodide corrosion inhibitor and a preparation method thereof. The Mannich base metal iodide corrosion inhibitor comprises components of the following mass percentage: 15 to 30 percent of the metal iodide of a condensate of ketone, aldehyde and amine, and 70 to 85 percent of complex, wherein the complex is made up of following materials with mass percentof: 5 to 15 percent of cetylpyridinium chloride, 5 to 20 percent of emulsifier, and 65 to 80 percent of solvent. The metal iodide of a condensate of ketone, aldehyde and amine can be obtained by reaction of the metal iodide and the condensate of ketone, aldehyde and amine synthesized with 1-naphthy lamine, paraformaldehyde, and ethyl phenyl ketone. The problem that other corrosion inhibitors can be easily decomposed at high temperature can be solved, the inconvenience in production caused by toxic material can be reduced, acidification and corrosion of hydrochloric acid at high temperature can be inhibited, the problem of corrosion by strong acid during the acidification fracturing of petroleum exploitation can be solved, and the goal of protecting oil pipes can be achieved.

The invention discloses anti-caries and antiallergic mouth wash, which belongs to the field of oral cavity care. The anti-caries and anti-sensitive mouth wash comprises 0.02 to 0.06 mass percent of ammonium fluorosilicate, 0.03 to 0.05 mass percent of cetylpyridinium chloride and auxiliary ingredients such as a moisturizing agent, a surfactant, a preservative and the like. Compared with the conventional antiallergic mouth wash, the anti-caries and antiallergic mouth wash has the advantages that: the ammonium fluorosilicate serving as a functional material is added into the mouth wash, so the antiallergic effect is more obvious and durable; the mouthfeel is good; the anti-caries and antiallergic mouth does not comprise alcohol, so the alcohol carcinogenic danger is reduced and the anti-caries and antiallergic mouth wash is safer; side effects such as teeth discoloring and the like are not generated; and anti-caries and antibacterial effects are achieved and oral health can be maintained better.

The present invention is directed to a preserved liquid aqueous pharmaceutical composition comprising one or more etherified cyclodextrin derivatives; one or more water-soluble preservatives; preferably selected from the group consisting of sorbic acid or salts thereof, preferably sodium sorbate, potassium sorbate, calcium sorbate; benzoic acid or salts thereof, preferably sodium benzoate; benzalkonium chloride; benzethonium chloride; cetylpyridinium chloride; sodium metabisulfite; sodium acetate; parabenes and salts thereof, preferably methylparabene, ethylparabene, propylparabene, butylparabene, butylparabene sodium; or combinations thereof; and at least one pharmaceutically active compound which is poorly water-soluble, very poorly water-soluble or water-insoluble. The liquid aqueous pharmaceutical composition provides an acceptable solubility of the pharmaceutically active compound, such as pimobendan, in aqueous solution whereby the water-soluble preservatives retain their effectiveness in the presence of the etherified cyclodextrin derivatives allowing the use in an oral administration form.

The invention discloses a method for ultra-filtration membrane strengthened ultra-filtration treatment of phenol-containing sewage. The method comprises: first adding cetylpyridinium chloride which is a cationic surfactant, and sodium carbonate into the phenol-containing sewage, stirring uniformly and standing for reaction where cetylpyridinium chloride monomer molecules produce micelles by self-assembly and then solubilize the phenol contained in the water; pumping the water to an ultra-filtration component for filtration where the cetylpyridinium chloride micelles with being solubilized the phenol contained in the water are intercepted by the ultra-filtration membrane so that the phenol contained in the water is removed. The phenol concentration in the sewage is 5mg / L-200mg / L; the addition of cetylpyridinium chloride is 20*10<-3>mol / L-30*10<-3>mol / L; the addition of sodium carbonate is 1*10<-3>mol / L-20*10<-3>mol / L; the weight of molecules intercepted by the ultra-filtration membrane is 6000-10000Dalton; the membrane operation pressure is 0.05MPa-0.20MPa. The method is carried out in an intermittent type, and the standing reaction time is 0.5-10h. In treating the phenol-containing sewage, the invention has excellent phenol removal performance, low energy consumption, simple operation, low surfactant consumption and low cost. In addition, the surfactant and the phenol can be recycled.

An oral moisturizer is disclosed to provide relief from dry mouth. The moisturizer may be provided in different flavors that are palatable, with clinical benefits such as anti-nausea, appetite stimulant, etc., in addition to relief from the deteriorating dental effects of dry mouth. One disclosed oral moisturizer includes glycerin, xylitol, sodium hyaluronate, cetylpyridinium chloride, polysorbate surfactants and a palatable flavor.

A polyantiseptic antimicrobial pharmaceutical composition for oral use, for the hygiene and treatment of oral diseases of bacterial, mycotic or viral etiology, for over-the-counter sale, without contraindications. The composition does not contain phenolic or, chlorophenolic compounds, and consists of a mixture of hydrogen peroxide, eugenol, natural camphor, zinc sulphate, sodium fluoride, xylitol, cetylpyridinium chloride and excipients. The formulation is used to deodorise, disinfect, astringe and soothe inflammation of the oral area, avoids the neoformation of bacterial plaque, prevents tooth cavities, inhibits the formation of dental tartar, improves the resistance of teeth to cavities, and treats and prevents oral aphthous ulcers.

A multi-purpose contact lens care solution having high antimicrobial activity comprising, in an aqueous liquid medium, cetylpyridinium chloride and a non-ionic surfactant. In one embodiment of the invention, the non-ionic surfactant is a poly(oxypropylene)-poly(oxyethylene) block copolymer. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and / or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.

Disclosed are oral care compositions having reduced tooth staining propensity and comprising in a pharmaceutically acceptable carrier, a cationic antimicrobial agent and an anti-stain agent comprising one or more materials from each of at least two of the following chemical groups:Group 1. anionic agents,Group 2. aldehydes, ketones, and other reactive carbonyl compounds andGroup 3. nonionic ethoxylated surfactants.Examples of cationic antimicrobial agent include quaternary ammonium compounds such as cetylpyridinium chloride, cetyl pyridinium fluoride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride and domiphen bromide; chlorhexidine; and metal ion sources to supply metal ions such as stannous, zinc or copper.

Heparan sulfate originating from rat tissue and its production are disclosed. The procedures is carried out by homogenizing rat tissue, degreasing, hydrolyzing by protease, hydrolyzing by alkali, deproteinizing, centrifugalizing, taking out purified liquor, dialyzing, depositing dialyzate by cetylpyridinium chloride, hydrolyzing by RNase and chondroitinase ABC, and separating by ionic exchanging column. It has special raw material, better product anticoagulant and antiradiation performances, and various Heparan sulfate. It can be used for research on medicinal molecular model structure and protein interaction. I

Precipitated silica comprising porous silica particles having a cumulative surface area for all pores having diameters greater than 500 Å of less than 6 m2 / g, as measured by mercury intrusion, and a percentage cetylpyridinium chloride (% CPC) Compatibility of greater than about 85%. The precipitated silica product is especially well-adapted for use in dentifrices containing cetylpyridinium chloride, which do not attach to the low surface area silica product in a meaningful level and thus remain available for antimicrobial action. Processes for making the silica product including the introduction of sodium sulfate powder during different process steps in order to enhance such a compatibility with CPC are provided.

The invention provides a medical disinfection coupling agent with disinfection and sterilization functions, which comprises the following components in percentage by weight: 0.3 percent of Carbomer 980 raw material powder, 0.12 percent of sodium hydroxide, 3 percent of glycerol, 1 percent of cetylpyridinium chloride, and the balance of purified water. The preparation method comprises the following steps: respectively dissolving Carbomer 980 and sodium hydroxide into purified water; stirring and mixing by virtue of a high-speed stirrer; adding glycerol, the disinfectant, the lubricant and the emollient; and stirring, defoaming and filling, and performing radiation disinfection through cobalt 60. The medical disinfection coupling agent has the characteristics of quick sterilization, broad spectrum of anti-bacterium, long bacteria inhibition time, no antibiotics, drug resistance prevention and the like, and is used for ultrasonic diagnosis, wherein a probe is contacted with mucosa; and the medical disinfection coupling agent has the advantages of wide raw material sources, simple preparation method and cost reduction.