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1 results about "Chondroitinase ABC" patented technology
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Chondroitinase ABC is purified from Proteus vulgaris. by cation exchange chromatography catalyzes the degradation of chondroitin sulfate A, chondroitin sulfate C, dermatan sulfate, chondroitin and hyaluronan to mainly disaccharideswith D-4hexuronate by the eliminative cleavage of 1,4-B-hexosaminyl linkages.
Targeted chondroitinase ABC fusion proteins and complexes thereof
Described herein are targeted ChABC fusion proteins, complexes thereof, and uses thereof. The targeted ChABC fusion proteins can include a ChABC polypeptide that can be linked to a Gal-3 polypeptide. Monomer targeted ChABC fusion proteins can form homogeneous or heterogeneous complexes. The targeted ChABC fusion proteins and complexes thereof can be formulated as pharmaceutical formulations. The targeted ChABC fusion proteins, complexes thereof, and formulations thereof can be administered to a subject in need thereof.
Owner:UNIV OF FLORIDA RESEARCH FOUNDATION INC