Medical disinfection coupling agent

A coupling agent and disinfectant technology, applied in the field of medical devices, can solve problems such as monotony and difficulty in adapting to various clinical needs, and achieve the effects of reducing costs, reducing the burden of medical expenses, and wide and stable sources

Active Publication Date: 2012-07-18
JIANGSU 139 MEDICAL DEVICES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now the products officially produced in China are all carbomer gel type, but the products are mainly ordinary type for intact skin, which is too monotonous and difficult to meet various clinical needs, especially intracavitary B-ultrasound, due to direct contact with mucous membrane, Sterilized coupling agents should be used first. The existing domestically available sterile coupling agents often use antibiotics as sterilizing agents, which are prone to drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A kind of medical sterilizing coupling agent is preferably formulated with the following raw materials in weight percentage:

[0019] Carbomer 980 0.3%;

[0020] Sodium hydroxide 0.12%;

[0021] Glycerin 3%;

[0022] Cetyl pyridinium chloride 1%;

[0023] Purified water balance.

[0024] Weigh carbomer 980 and sodium hydroxide respectively, and dissolve them completely in purified water; pour the sodium hydroxide solution into the carbomer solution while stirring, and continue stirring for 20-30 minutes; Glycerin and cetylpyridinium chloride are stirred evenly; the stirred mixture is placed in an ultrasonic degassing tank for degassing, and after the liquid is transparent and gelatinous, it is filled and sterilized by cobalt 60 radiation. The cetylpyridinium chloride mentioned above is in a solution state, which is prepared by dissolving anhydrous cetylpyridinium chloride in 95% medical alcohol, stirring and dissolving.

Embodiment 2

[0026] A kind of medical sterilizing coupling agent is preferably formulated with the following raw materials in weight percentage:

[0027] Carbomer 980 0.3%;

[0028] Sodium hydroxide 0.12%;

[0029] Glycerin 3%;

[0030] Chlorine dioxide 1%;

[0031] Purified water balance.

[0032] Weigh carbomer 980 and sodium hydroxide respectively, and dissolve them completely in purified water; pour the sodium hydroxide solution into the carbomer solution while stirring, and continue stirring for 20-30 minutes; Glycerin and chlorine dioxide are stirred evenly; the stirred mixture is placed in an ultrasonic degassing tank for degassing, and after the liquid is transparent and gelatinous, it is filled and sterilized by cobalt 60 radiation.

Embodiment 3

[0034] A kind of medical sterilizing coupling agent is preferably formulated with the following raw materials in weight percentage:

[0035] Carbomer 980 0.3%;

[0036] Sodium hydroxide 0.12%;

[0037] Glycerin 3%;

[0038] Triclosan 0.5%;

[0039] Sodium Laureth Sulfate 0.3%;

[0040] Vitamin B5 0.2%;

[0041] Purified water balance.

[0042] Weigh carbomer 980 and sodium hydroxide respectively, and dissolve them completely in purified water; pour the sodium hydroxide solution into the carbomer solution while stirring, and continue stirring for 20-30 minutes; Glycerin, triclosan, sodium lauryl ether sulfate and vitamin B5, stir evenly; place the stirred mixture in an ultrasonic degassing tank for degassing, wait until the liquid is transparent and gel-like, fill it and sterilize it with cobalt 60 radiation deal with.

[0043] In the above technical solution, the cetylpyridinium chloride is a cationic quaternary ammonium compound, which inhibits and kills bacteria mainl...

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PUM

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Abstract

The invention provides a medical disinfection coupling agent with disinfection and sterilization functions, which comprises the following components in percentage by weight: 0.3 percent of Carbomer 980 raw material powder, 0.12 percent of sodium hydroxide, 3 percent of glycerol, 1 percent of cetylpyridinium chloride, and the balance of purified water. The preparation method comprises the following steps: respectively dissolving Carbomer 980 and sodium hydroxide into purified water; stirring and mixing by virtue of a high-speed stirrer; adding glycerol, the disinfectant, the lubricant and the emollient; and stirring, defoaming and filling, and performing radiation disinfection through cobalt 60. The medical disinfection coupling agent has the characteristics of quick sterilization, broad spectrum of anti-bacterium, long bacteria inhibition time, no antibiotics, drug resistance prevention and the like, and is used for ultrasonic diagnosis, wherein a probe is contacted with mucosa; and the medical disinfection coupling agent has the advantages of wide raw material sources, simple preparation method and cost reduction.

Description

technical field [0001] The invention relates to a medical disinfection coupling agent, in particular to a medical disinfection coupling agent with disinfection function used in ultrasonic detection and treatment of skin and cavity mucous membrane, belonging to the field of medical devices. Background technique [0002] When ultrasound is used clinically for diagnosis and treatment, in order to avoid the interference of gas on the image, a layer of couplant will be applied to the ultrasound probe. In clinical operations, the couplant needs to be in close contact with the skin and the radiating surface of the probe. Therefore, in addition to the acoustic properties, the couplant must also meet the requirements of not irritating the skin, not damaging the probe, and not sticking to the clothes. Cellulosic and paraffin oil based formulations have significant deficiencies in these respects. The national pharmaceutical industry standard "YY 0299-2008 Medical Ultrasonic Coupling A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 孙开源
Owner JIANGSU 139 MEDICAL DEVICES
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