4results about How to "Reliable source" patented technology

This invention discloses a feeding device for the production of hydroxyapatite powder, aiming to solve the problems of uneven feeding, clogging, and dust pollution caused by the poor flowability and easy agglomeration of this type of powder. The device includes a frame, a feeding channel, a crushing device and a dust removal assembly located within the channel. The crushing device includes a fixed rod and a movable crushing shovel driven by a drive assembly, effectively preventing material bridging and agglomeration through active, reciprocating crushing action. The dust removal assembly includes a suction chamber, a filter screen, and a cleaning roller brush. When the crushing shovel moves, this mechanism can be periodically actuated, driving the cleaning roller brush to automatically clean the dust accumulated on the filter screen. This invention cleverly combines active crushing with a mechanically linked self-cleaning dust removal function, eliminating the need for an additional power source for the cleaning function. Its compact structure enables uniform, stable, and dust-free feeding, effectively improving production efficiency and environmental quality.

The application provides an extraction method of high-purity type I collagen, and belongs to the technical field of biomedical materials. The application realizes efficient and stable extraction of type I collagen by accurately selecting process conditions, significantly improves the purity and extraction efficiency of the target product, and the obtained collagen has complete three-dimensional structure, extremely low impurity residue and water content, greatly improves the biocompatibility and storage stability of the product, the method is simple in process, easy to control in condition, does not need complex large-scale equipment, is suitable for large-scale production, provides a reliable high-quality raw material source for high-end implant medical devices, and expands the application prospect of collagen in the field of biomedicine.

This invention discloses an anti-Dabie Banda virus Gn protein nanobody, a bispecific antibody, and their applications, belonging to the field of biodetection technology. This invention constructs an alpaca natural nanobody library, using recombinantly expressed Gn protein as the antigen. Through multiple rounds of gradient screening using phage display technology, three nanobodies—G15, G20, and G40—that specifically bind to the Dabie Banda virus Gn protein are obtained. All three antibodies exhibit excellent antigen-binding specificity and virus-neutralizing activity; among them, G40 shows the most prominent neutralizing effect. The bispecific antibody G40-C1q, constructed based on G40, combines Gn protein and human C1q protein, achieving a synergistic effect of antiviral activity and inhibition of inflammatory damage. It can be used for the development of drugs for the prevention and treatment of Dabie Banda virus infection and for high-specificity detection reagents, providing candidate antibody drugs for the treatment of fever with thrombocytopenia syndrome, and providing a reliable tool for virus-related research, disease diagnosis, and clinical translation.

The application discloses a kind of fluorescent optical fiber temperature measurement systems and AI intelligent temperature measurement methods for electric power equipment, including intelligent sensor, temperature sensor and optical fiber link, intelligent sensor, temperature sensor and optical fiber link;Intelligent sensor includes temperature measurement demodulation device and data processing device;Temperature sensor is fluorescent optical fiber temperature measurement probe, contains temperature measurement fluorescent area and light absorption heating area and both are mutually contacted;Temperature measurement demodulation device exports excitation light to obtain fluorescent signal demodulation temperature measurement temperature, and exports heating light to generate self-checking heat pulse;Data processing device is based on temperature change after pulse to obtain temperature drop rate, rate is less than threshold value alarm, rate is greater than or equal to threshold value timing after re-measurement temperature, the present application solves the problem of temperature measurement reliability decline caused by probe adhesion contact degradation in electric power equipment temperature measurement.