19results about How to "Reliable source" patented technology

The invention relates to the technical field of image processing, in particular to a numerical simulation method and system based on erosive wear of a titanium alloy pump valve, and the method comprises the steps: eroding the titanium alloy pump valve based on the titanium alloy pump valve, the flow velocity range, the pressure range, the particle concentration and the particle size distribution to obtain a worn workpiece and a three-dimensional scanning wear morphology image, constructing an erosion simulation model, calculating particle impact force, wear depth and particle kinetic energy, constructing a simulated wear depth histogram, calculating a height gradient and a gradient dynamic threshold value, segmenting a gradient segmentation image, calculating a depth dynamic threshold value and depth information, segmenting an actual wear distribution diagram, marking the actual wear distribution diagram to obtain a marked area, calculating the wear degree of the marked area, and calculating the wear degree of the marked area. And an actual abrasion depth histogram is constructed, the erosion simulation model is adjusted, an adjusted erosion simulation model is obtained, and numerical simulation is completed. According to the method, the accuracy of numerical simulation of the erosive wear of the titanium alloy pump valve can be improved.

The present application relates to the technical field of industrial unmanned aerial vehicle application and intelligent scheduling, and particularly discloses an unmanned aerial vehicle highway inspection task intelligent planning management system, which comprises a task input module, an intelligent planning engine, a task execution management module, a data hub and a feedback optimization module; the task input module receives and checks and analyzes inspection task requirements and highway basic information; the intelligent planning engine decomposes task priorities based on highway multi-dimensional attributes, dynamically allocates unmanned aerial vehicle resources and generates an optimal path meeting multiple constraints; the task execution management module issues adaptive instructions, monitors unmanned aerial vehicle states and processes inspection data; the data hub uniformly stores whole-process data; and the feedback optimization module optimizes a decision model based on historical data. The present application improves inspection planning accuracy and resource utilization, guarantees data quality, realizes self-evolution and ensures efficient and reliable highway inspection.

The invention relates to the technical field of marine antifouling, in particular to a brusatol derivative and application of the brusatol derivative in marine biofouling resistance, and structurally modifies brusatol, which is one of main compounds in plant brucea javanica with wide sources, by utilizing a directional multi-target ligand strategy to obtain the brusatol derivative. Strong anti-pollution active groups (halogen, cyano groups, benzene rings, heterocyclic rings and the like) derived from the ocean are hybridized on a brusatol mother nucleus molecule, and a series of novel brusatol derivatives hybridized with the strongly anti-pollution active groups derived from the ocean are successfully synthesized. The compounds show good anti-barnacle adhesion activity in anti-adhesion experiments of barnacles, and have low toxicity to target organisms. According to the method, the variety of candidate compounds of the anti-fouling agent is enriched, a new way is provided for developing novel and efficient anti-fouling coatings, and the method has good application prospects and industrial value.

The present application belongs to the field of microorganism identification, and discloses a biochemical numerical identification method of lactic acid bacteria strains. The present application provides a biochemical numerical identification method for identifying 44 species / subspecies of lactic acid bacteria, including a biochemical reaction positive probability database and a numerical identification kit of 47 biochemical combinations. The lactic acid bacteria biochemical reaction positive rate database in the present application is obtained by statistically analyzing a large number of isolated strains in the laboratory, conducting biochemical experiments and collecting lactic acid bacteria biochemical data from Bac Dive website, thereby ensuring the accuracy and effectiveness of the data. Meanwhile, the present application is used to identify 14 lactic acid bacteria standard strains and 171 lactic acid bacteria isolated strains, and the accuracy rate of the results reaches 98.92%.

This invention discloses a feeding device for the production of hydroxyapatite powder, aiming to solve the problems of uneven feeding, clogging, and dust pollution caused by the poor flowability and easy agglomeration of this type of powder. The device includes a frame, a feeding channel, a crushing device and a dust removal assembly located within the channel. The crushing device includes a fixed rod and a movable crushing shovel driven by a drive assembly, effectively preventing material bridging and agglomeration through active, reciprocating crushing action. The dust removal assembly includes a suction chamber, a filter screen, and a cleaning roller brush. When the crushing shovel moves, this mechanism can be periodically actuated, driving the cleaning roller brush to automatically clean the dust accumulated on the filter screen. This invention cleverly combines active crushing with a mechanically linked self-cleaning dust removal function, eliminating the need for an additional power source for the cleaning function. Its compact structure enables uniform, stable, and dust-free feeding, effectively improving production efficiency and environmental quality.

The invention provides an etiazepine antigen binding molecule and application thereof, and relates to the technical field of biology. The etiazepine antigen binding molecule contains complementary determining regions HCDR1, HCDR2 and HCDR3 of a heavy chain variable region, and complementary determining regions LCDR1, LCDR2 and LCDR3 of a light chain variable region; the HCDR1, the HCDR2 and the HCDR3 comprise an amino acid sequence which is consistent with the amino acid sequence of the HCDR1, the amino acid sequence of the HCDR2 and the amino acid sequence of the HCDR3 of the heavy chain variable region shown in SEQ ID NO.1; the LCDR1, the LCDR2 and the LCDR3 comprise amino acid sequences which are consistent with the amino acid sequences of the LCDR1, the LCDR2 and the LCDR3 of the light chain variable region as shown in SEQ ID NO.2. The etiazepine antigen binding molecule can bind to an etiazepine antigen, and can be used for a method or a product for detecting the etiazepine antigen based on an immunological principle.

The invention provides an anti-quetiapine antibody or an antigen binding fragment thereof and application thereof, and relates to the technical field of biology. The antibody or the antigen binding fragment thereof contains a complementarity determining region of a heavy chain variable region and a complementarity determining region of a light chain variable region, wherein the complementarity determining region of the heavy chain variable region comprises amino acid sequences consistent with HCDR1, HCDR2 and HCDR3 of the heavy chain variable region as shown in SEQ ID NO.1; the complementarity determining region of the light chain variable region comprises amino acid sequences consistent with LCDR1, LCDR2 and LCDR3 of the light chain variable region as shown in SEQ ID NO.2. The antibody or the antigen binding fragment thereof can be combined with quetiapine, and can be used for a method or a product for detecting quetiapine based on an immunological principle.

The invention belongs to the technical field of biological medicine, and discloses a nano-motor drug-loaded particle and a preparation method and application thereof, the nano-motor drug-loaded particle is formed by loading platinum nanoparticles and a methylene blue drug on a DNA tetrahedral structure; the nano-motor drug-loaded particle can enhance the uptake of tumor cells to a photosensitizer methylene blue (MB) and realize deep penetration to tumors at the same time, can reduce the dosage of drugs required by a conventional system for treating cancers, and is higher in safety and lower in adverse reaction, and the nano-motor drug-loaded particle provided by the invention has a good application prospect. The material is reliable in source, simple to prepare and high in biocompatibility, specifically responds to photodynamic therapy, and efficiently inhibits tumor cell growth.

The application provides an extraction method of high-purity type I collagen, and belongs to the technical field of biomedical materials. The application realizes efficient and stable extraction of type I collagen by accurately selecting process conditions, significantly improves the purity and extraction efficiency of the target product, and the obtained collagen has complete three-dimensional structure, extremely low impurity residue and water content, greatly improves the biocompatibility and storage stability of the product, the method is simple in process, easy to control in condition, does not need complex large-scale equipment, is suitable for large-scale production, provides a reliable high-quality raw material source for high-end implant medical devices, and expands the application prospect of collagen in the field of biomedicine.

This invention discloses an anti-Dabie Banda virus Gn protein nanobody, a bispecific antibody, and their applications, belonging to the field of biodetection technology. This invention constructs an alpaca natural nanobody library, using recombinantly expressed Gn protein as the antigen. Through multiple rounds of gradient screening using phage display technology, three nanobodies—G15, G20, and G40—that specifically bind to the Dabie Banda virus Gn protein are obtained. All three antibodies exhibit excellent antigen-binding specificity and virus-neutralizing activity; among them, G40 shows the most prominent neutralizing effect. The bispecific antibody G40-C1q, constructed based on G40, combines Gn protein and human C1q protein, achieving a synergistic effect of antiviral activity and inhibition of inflammatory damage. It can be used for the development of drugs for the prevention and treatment of Dabie Banda virus infection and for high-specificity detection reagents, providing candidate antibody drugs for the treatment of fever with thrombocytopenia syndrome, and providing a reliable tool for virus-related research, disease diagnosis, and clinical translation.

The invention discloses a traditional Chinese medicine composition for treating pet cough and a preparation method thereof, and the traditional Chinese medicine composition comprises the following components in parts by weight: 8-16 parts of ephedra, 5-12 parts of almond, 5-8 parts of houttuynia cordata, 2-5 parts of licorice extract, 2-5 parts of platycodon grandiflorum extract, 3-5 parts of perilla leaf, 2-4 parts of herba siegesbeckiae, 0.5-1.5 parts of almond oil, 0.5-1.5 parts of borneol, 1-2 parts of loratadine and 3-6 parts of mannitol. According to the traditional Chinese medicine composition, through the synergistic effect of various traditional Chinese medicine components and western medicine components, the comprehensive curative effect can be achieved. Traditional Chinese medicine components such as ephedra, almond and houttuynia cordata can effectively relieve cough, clear lung and reduce phlegm; western medicine components such as loratadine and a licorice extract have anti-allergic and anti-inflammatory effects and help to relieve cough caused by allergy or infection.

The invention provides a pramoxine hydrochloride and fluconazole combined pharmaceutical composition for resisting candida albicans biofilm infection and application of the pharmaceutical composition, and belongs to the technical field of biological medicine. Aiming at the problem of inherent drug resistance of a candida albicans biological membrane to azole drugs, drug relocation strategy screening finds that pramoxine hydrochloride can significantly enhance the inhibitory activity of fluconazole to the candida albicans biological membrane. The action mechanism is as follows: pramoxapine hydrochloride is specifically targeted to key protein mevalonate kinase in a farnesyl pyrophosphate synthesis route in candida albicans, biosynthesis of ubiquinone is inhibited, the active oxygen level of mitochondria is increased, the mitochondrial function is destroyed, the hypha length, the biological membrane thickness and extracellular matrix secretion of candida albicans are reduced, and the activity of pramoxapine hydrochloride in the candida albicans is improved. And finally, the anti-biofilm effect of fluconazole is improved. The invention provides a safe and efficient new strategy for resisting Candida albicans biofilm infection, and provides a new pharmaceutical composition and an action target for clinical treatment of biofilm related fungal infection.

The invention belongs to the technical field of traditional Chinese medicine analysis, and particularly relates to a construction method and application of a specific chromatogram of an achyranthes aspera throat-clearing mixture. According to the invention, the spanning from single index control to overall quality evaluation is realized; the specific characteristic spectrum method for the achyranthes aspera throat-clearing mixture is established for the first time, and the limitation that only the content of a single component is measured in the prior art is broken through. By simultaneously monitoring the five key characteristic peaks of chlorogenic acid, caffeic acid, bergenin, geniposide and catechin and the consistency of the overall spectrum of the five key characteristic peaks, the basic material feeding condition and the matching stability of the monarch, minister, assistant and guide medicines in the preparation can be comprehensively reflected, so that the overall quality and the uniformity of the curative effect of the product are more scientifically guaranteed.

The present application discloses a device registration method, a device and a medium, a registration server, and an authentication server, and relates to the field of security authentication technology. The device registration method applied to the registration server comprises: upon receiving a product identification and encrypted registration information sent by an electronic device, retrieving a product public key according to the product identification, wherein the encrypted registration information is information obtained by the authentication server using a product private key to encrypt the registration information and a first character string, and the first character string is a character string obtained by the authentication server using a device public key to encrypt the registration information; decrypting the encrypted registration information using the product public key to obtain the registration information and the first character string, wherein the registration information is information determined by the authentication server when the identity authentication of the electronic device passes; verifying the first character string according to the registration information; and confirming that the electronic device is successfully registered when the first character string verification passes, thereby improving the security of the device self-registration authentication process.

The invention relates to a carrying equipment high-performance component thermal forming process quality tracing method, and belongs to the technical field of metal thermal forming machining, and the carrying equipment high-performance component thermal forming process quality tracing method comprises the following steps: carrying out data fusion on collected thermal forming process feature data to obtain fusion data, the thermoforming characteristic data comprises thermoforming process equipment state parameters, thermoforming process parameters, thermoformed workpiece macroscopic morphology and geometric dimension precision, microstructure grain size and phase size and distribution data; constructing a thermoforming digital twin model based on thermoforming process equipment, the geometric model of the thermoforming workpiece and the fusion data; and finishing quality tracing of the thermoforming process based on the thermoforming digital twin model. The problems that in the prior art, due to the fact that the technological process in the process can only be reversely traced from the final result, the hot forming quality traceability difficulty is large, the accuracy is poor, and the efficiency is low are effectively solved.

The application discloses a kind of fluorescent optical fiber temperature measurement systems and AI intelligent temperature measurement methods for electric power equipment, including intelligent sensor, temperature sensor and optical fiber link, intelligent sensor, temperature sensor and optical fiber link;Intelligent sensor includes temperature measurement demodulation device and data processing device;Temperature sensor is fluorescent optical fiber temperature measurement probe, contains temperature measurement fluorescent area and light absorption heating area and both are mutually contacted;Temperature measurement demodulation device exports excitation light to obtain fluorescent signal demodulation temperature measurement temperature, and exports heating light to generate self-checking heat pulse;Data processing device is based on temperature change after pulse to obtain temperature drop rate, rate is less than threshold value alarm, rate is greater than or equal to threshold value timing after re-measurement temperature, the present application solves the problem of temperature measurement reliability decline caused by probe adhesion contact degradation in electric power equipment temperature measurement.

The invention discloses a fluorescent optical fiber temperature measurement system for power equipment and an AI intelligent temperature measurement method. The fluorescent optical fiber temperature measurement system comprises an intelligent sensor, a temperature sensor and an optical fiber link. The intelligent sensor comprises a temperature measurement demodulation device and a data processing device; the temperature sensor is a fluorescent optical fiber temperature measurement probe and comprises a temperature measurement fluorescent area and a light absorption heating area which are in contact with each other; the temperature measurement demodulation device outputs excitation light to obtain a fluorescence signal to demodulate the temperature measurement temperature, and outputs heating light to generate a self-checking thermal pulse; the data processing device calculates the temperature drop rate based on the post-pulse temperature change, an alarm is given when the rate is smaller than a threshold value, and the temperature is measured again after the rate is larger than or equal to the threshold value, and the problem that the temperature measurement reliability is reduced due to probe attachment contact degradation in the temperature measurement process of the power equipment is solved.

The invention discloses a Linux system port multiplexing attack detection method and device, and the method comprises the steps: detecting a setsocket system to call a first process, obtaining corresponding process information, and transmitting the corresponding process information to an application layer; obtaining a first socket inode number in the first process information called by the setsocket system through the application layer; acquiring a first socket corresponding to the inode number of the first socket in the socket socket data table, traversing the socket socket data table, and acquiring a second socket sharing a port with the first socket according to a port sharing detection rule; and on the basis of the first socket and the second socket, judging whether corresponding port multiplexing attack behaviors exist when the setsocket system calls the first process and when the setsocket system calls the second process or not. Through linkage detection of a system kernel and an application layer, real-time automatic detection of a port multiplexing attack behavior is realized.

The invention discloses a storage method and application of cymbidium seeds, and belongs to the technical field of agricultural product storage. According to the method, mixed and sterilized sandy soil and cymbidium orchid seeds are alternately treated at two temperature intervals of 2-6 DEG C and 20-30 DEG C, natural environment temperature change is simulated, seed aging is delayed, and seed vitality, storage stability and germination rate are improved. Meanwhile, mature cymbidium capsules are collected and dried in the shade till the water content of the seeds is smaller than 10%, river sand and matrix soil are mixed and sterilized to serve as a storage medium, the air permeability and the water-retaining property are guaranteed, and the infection risk is reduced; a proper humidity environment is kept by spraying a mixed sterilizing solution, so that the storage effect is further improved; and the effectiveness and the controllability of the storage process are ensured by monitoring the temperature and the humidity in real time. The method is applied to artificial breeding of cymbidium orchid and storage of orchid seeds, the germination rate and the seedling success rate are increased, the genetic stability is kept, and powerful support is provided for production, research and application of cymbidium orchid and orchid.