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9results about How to "Reliable source" patented technology

An unmanned aerial vehicle highway inspection task intelligent planning management system

ActiveCN121032150BData source is reliableReliable sourceForecastingDecision modelUncrewed vehicle
The present application relates to the technical field of industrial unmanned aerial vehicle application and intelligent scheduling, and particularly discloses an unmanned aerial vehicle highway inspection task intelligent planning management system, which comprises a task input module, an intelligent planning engine, a task execution management module, a data hub and a feedback optimization module; the task input module receives and checks and analyzes inspection task requirements and highway basic information; the intelligent planning engine decomposes task priorities based on highway multi-dimensional attributes, dynamically allocates unmanned aerial vehicle resources and generates an optimal path meeting multiple constraints; the task execution management module issues adaptive instructions, monitors unmanned aerial vehicle states and processes inspection data; the data hub uniformly stores whole-process data; and the feedback optimization module optimizes a decision model based on historical data. The present application improves inspection planning accuracy and resource utilization, guarantees data quality, realizes self-evolution and ensures efficient and reliable highway inspection.
Owner:FUJIAN EXPRESSWAY TECH INNOVATION RES INST CO LTD +1

Biochemical numerical identification method of lactic acid bacterial species

The present application belongs to the field of microorganism identification, and discloses a biochemical numerical identification method of lactic acid bacteria strains. The present application provides a biochemical numerical identification method for identifying 44 species / subspecies of lactic acid bacteria, including a biochemical reaction positive probability database and a numerical identification kit of 47 biochemical combinations. The lactic acid bacteria biochemical reaction positive rate database in the present application is obtained by statistically analyzing a large number of isolated strains in the laboratory, conducting biochemical experiments and collecting lactic acid bacteria biochemical data from Bac Dive website, thereby ensuring the accuracy and effectiveness of the data. Meanwhile, the present application is used to identify 14 lactic acid bacteria standard strains and 171 lactic acid bacteria isolated strains, and the accuracy rate of the results reaches 98.92%.
Owner:GUANGDONG HUANKAI BIOLOGICAL SCI & TECH CO LTD +3

A feeding device suitable for the production of hydroxyapatite powder

ActiveCN224443099UEffectively eliminateprevent bridgingProcess engineeringEnvironmental engineering
This invention discloses a feeding device for the production of hydroxyapatite powder, aiming to solve the problems of uneven feeding, clogging, and dust pollution caused by the poor flowability and easy agglomeration of this type of powder. The device includes a frame, a feeding channel, a crushing device and a dust removal assembly located within the channel. The crushing device includes a fixed rod and a movable crushing shovel driven by a drive assembly, effectively preventing material bridging and agglomeration through active, reciprocating crushing action. The dust removal assembly includes a suction chamber, a filter screen, and a cleaning roller brush. When the crushing shovel moves, this mechanism can be periodically actuated, driving the cleaning roller brush to automatically clean the dust accumulated on the filter screen. This invention cleverly combines active crushing with a mechanically linked self-cleaning dust removal function, eliminating the need for an additional power source for the cleaning function. Its compact structure enables uniform, stable, and dust-free feeding, effectively improving production efficiency and environmental quality.
Owner:BIANKRYPTON MEDICAL TECH (SHANGHAI) CO LTD

A method for extracting high-purity collagen type I

The application provides an extraction method of high-purity type I collagen, and belongs to the technical field of biomedical materials. The application realizes efficient and stable extraction of type I collagen by accurately selecting process conditions, significantly improves the purity and extraction efficiency of the target product, and the obtained collagen has complete three-dimensional structure, extremely low impurity residue and water content, greatly improves the biocompatibility and storage stability of the product, the method is simple in process, easy to control in condition, does not need complex large-scale equipment, is suitable for large-scale production, provides a reliable high-quality raw material source for high-end implant medical devices, and expands the application prospect of collagen in the field of biomedicine.
Owner:TIANXINFU (BEIJING) MEDICAL APPLIANCE CO LTD

A nanobody against Dabie Bandar virus Gn protein, a bispecific antibody and its application

This invention discloses an anti-Dabie Banda virus Gn protein nanobody, a bispecific antibody, and their applications, belonging to the field of biodetection technology. This invention constructs an alpaca natural nanobody library, using recombinantly expressed Gn protein as the antigen. Through multiple rounds of gradient screening using phage display technology, three nanobodies—G15, G20, and G40—that specifically bind to the Dabie Banda virus Gn protein are obtained. All three antibodies exhibit excellent antigen-binding specificity and virus-neutralizing activity; among them, G40 shows the most prominent neutralizing effect. The bispecific antibody G40-C1q, constructed based on G40, combines Gn protein and human C1q protein, achieving a synergistic effect of antiviral activity and inhibition of inflammatory damage. It can be used for the development of drugs for the prevention and treatment of Dabie Banda virus infection and for high-specificity detection reagents, providing candidate antibody drugs for the treatment of fever with thrombocytopenia syndrome, and providing a reliable tool for virus-related research, disease diagnosis, and clinical translation.
Owner:NANJING MEDICAL UNIV

Pharmaceutical composition for resisting candida albicans biofilm infection through combination of pramoxine hydrochloride and fluconazole and application of pharmaceutical composition

PendingCN121943917Ahigh activityReduce inhibitory concentrationOrganic active ingredientsAntimycoticsCell-Extracellular MatrixEnzyme inhibition
The invention provides a pramoxine hydrochloride and fluconazole combined pharmaceutical composition for resisting candida albicans biofilm infection and application of the pharmaceutical composition, and belongs to the technical field of biological medicine. Aiming at the problem of inherent drug resistance of a candida albicans biological membrane to azole drugs, drug relocation strategy screening finds that pramoxine hydrochloride can significantly enhance the inhibitory activity of fluconazole to the candida albicans biological membrane. The action mechanism is as follows: pramoxapine hydrochloride is specifically targeted to key protein mevalonate kinase in a farnesyl pyrophosphate synthesis route in candida albicans, biosynthesis of ubiquinone is inhibited, the active oxygen level of mitochondria is increased, the mitochondrial function is destroyed, the hypha length, the biological membrane thickness and extracellular matrix secretion of candida albicans are reduced, and the activity of pramoxapine hydrochloride in the candida albicans is improved. And finally, the anti-biofilm effect of fluconazole is improved. The invention provides a safe and efficient new strategy for resisting Candida albicans biofilm infection, and provides a new pharmaceutical composition and an action target for clinical treatment of biofilm related fungal infection.
Owner:TONGJI UNIV

Construction method and application of specific chromatogram of achyranthes aspera throat-clearing mixture

The invention belongs to the technical field of traditional Chinese medicine analysis, and particularly relates to a construction method and application of a specific chromatogram of an achyranthes aspera throat-clearing mixture. According to the invention, the spanning from single index control to overall quality evaluation is realized; the specific characteristic spectrum method for the achyranthes aspera throat-clearing mixture is established for the first time, and the limitation that only the content of a single component is measured in the prior art is broken through. By simultaneously monitoring the five key characteristic peaks of chlorogenic acid, caffeic acid, bergenin, geniposide and catechin and the consistency of the overall spectrum of the five key characteristic peaks, the basic material feeding condition and the matching stability of the monarch, minister, assistant and guide medicines in the preparation can be comprehensively reflected, so that the overall quality and the uniformity of the curative effect of the product are more scientifically guaranteed.
Owner:WUYUAN MATERIA MEDICA (SHANDONG) HEALTH TECH CO LTD +1

A fluorescent optical fiber temperature measurement system for power equipment and an AI intelligent temperature measurement method

The application discloses a kind of fluorescent optical fiber temperature measurement systems and AI intelligent temperature measurement methods for electric power equipment, including intelligent sensor, temperature sensor and optical fiber link, intelligent sensor, temperature sensor and optical fiber link;Intelligent sensor includes temperature measurement demodulation device and data processing device;Temperature sensor is fluorescent optical fiber temperature measurement probe, contains temperature measurement fluorescent area and light absorption heating area and both are mutually contacted;Temperature measurement demodulation device exports excitation light to obtain fluorescent signal demodulation temperature measurement temperature, and exports heating light to generate self-checking heat pulse;Data processing device is based on temperature change after pulse to obtain temperature drop rate, rate is less than threshold value alarm, rate is greater than or equal to threshold value timing after re-measurement temperature, the present application solves the problem of temperature measurement reliability decline caused by probe adhesion contact degradation in electric power equipment temperature measurement.
Owner:HEBEI XIAODUN TECH CO LTD

Fluorescent optical fiber temperature measurement system for power equipment and AI intelligent temperature measurement method

The invention discloses a fluorescent optical fiber temperature measurement system for power equipment and an AI intelligent temperature measurement method. The fluorescent optical fiber temperature measurement system comprises an intelligent sensor, a temperature sensor and an optical fiber link. The intelligent sensor comprises a temperature measurement demodulation device and a data processing device; the temperature sensor is a fluorescent optical fiber temperature measurement probe and comprises a temperature measurement fluorescent area and a light absorption heating area which are in contact with each other; the temperature measurement demodulation device outputs excitation light to obtain a fluorescence signal to demodulate the temperature measurement temperature, and outputs heating light to generate a self-checking thermal pulse; the data processing device calculates the temperature drop rate based on the post-pulse temperature change, an alarm is given when the rate is smaller than a threshold value, and the temperature is measured again after the rate is larger than or equal to the threshold value, and the problem that the temperature measurement reliability is reduced due to probe attachment contact degradation in the temperature measurement process of the power equipment is solved.
Owner:HEBEI XIAODUN TECH CO LTD